From owner-molreps@hgmp.mrc.ac.uk Tue Mar 14 08:50:58 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id B115C17ADC; Tue, 14 Mar 2000 08:50:57 +0000 (GMT) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 1) id 3AB4917A91; Tue, 14 Mar 2000 08:50:55 +0000 (GMT) To: molreps@net.bio.net Newsgroups: bionet.molecules.repertoires From: grizzlyan@mindspring.com ("Michael Sherrell") Subject: Sequencers, synthesizers, Mass Specs, NMRs available Date: 14 Mar 2000 00:15:53 -0000 Organization: BIOSCI/MRC Human Genome Mapping Project Resource Centre Message-ID: <003b01bf8d4a$87e08d80$e56079a5@rossbranch> Sender: owner-molreps@hgmp.mrc.ac.uk Precedence: bulk Sequencers, synthesizers, Mass Specs, NMRs for sale: *Peptide and oligo synthesizers and sequencers: Expedite 8909: $16,000. Rebuilt; 90-day warranty Expedite 8909: $23,000. Includes M.O.S.S., warranty     ABI 392: $5,000. Complete and working; + $2,000 for rebuild and warranty     ABI 394: $12,500. Valve blocks rebuilt; 90-day warranty; +$1K/1 yr. warr.     ABI 390Z: $11,000. 50-100uM yields. Rebuilt w/ 90-day warranty     ABI 3948: $49,000 obo. Working well in lab now.     ABI 310: $39,000       Includes Genotyper software     ABI 373 stretch: $9,000. 36-lane 5-filter, Big Dye upgrade     ABI 373 stretch: $15,000. 64-lane 5-filter non-Big Dye     ABI 377: $45,000(!). 96-lane; Sequencing mod.; under svc. contract.     Li-Cor 4200L-2: $31,500     ABI 430: $11,500. Rebuilt, 90-day warranty     ABI 431: $12,500. Rebuilt, 90-day warranty     ABI 433: $19,000. Rebuilt, 90-day warranty     ACT 200, 357-MPS and 400: call for pricing *LC/MS & MS/MS:     [Sciex is a Perkin Elmer product]     Sciex API III+: $48,000. Triple quad: ES, APCI; +$10K/intall w/ 90-day warr.     Sciex API 365: $94,500. TurboIonspray + APCI; + $15,000/PE install/warranty     Sciex 100: $39,000. Same specs as the 150 but slightly larger. +$8,000/install & 90-day warr.     Micromass Quattro II: $79,000. 1995 model; non-Z spray. Install, license & 90-day warr. + $14,500; Z-spray upgrade available.     Finnigan TSQ 7000: $ 82,500. LC + GC; current software (Y2K-ok); API-1 source     Finnigan TSQ 700: $ 60,000. 1993; API 1, electrospray, APCI, DCI; new Alpha workstn (Y2K-ok); includes factory install + factory 90-day warranty     HP 1100 MSD: $92,000. APCI & API-es, ~14 mos. old     Kratos Concept H: make offer. 1994 double sector hi res: EI, CI, FAB, LS, ESI, APCI; GC & LC.     MAT 95: $260,000. Hi res mag sector. 1994, ES, APCI, FAB, Thermospray, GC interface, install, delivery, 1 yr warranty     Finnigan MAT 90: <$50,000. Hi-resolution magnetic sector *NMRs:     Varian Unity 500+: $200-250,000, depending on options; incl. install & warranty     Varian Unity 500: $185,000. BB and C-P probes; price includes install & warranty     Varian Unity 300: $80-120,000. Install/warranty included; price depends on probes, other accessories     Bruker AM 500: $125,000. 52mm magnet; Aspect 3000; 1H/13C probehead; install available     Bruker AMX 500: $85,000. Install extra     Bruker AM360: $85,000. Broadband; widebore; U.S. install included     Bruker AC270: $39,500. Install included     Bruker AC200: $39,000. Install included. Excellent hold time.     Bruker NR80: $19,000. Non-cryo; price includes install but not shipping. *Other expensive hi-tech items: Bio-Dot sub-microliter 8-channel aspirate/dispense system (typically 96-well microplate source, glass slide, microwell plate or membrane target), ~ 2 years old. New Brunswick Bioflow 4000 fermenter, 14 liter model, sterilizable in place, 1 yr. old, used 4x, pd $39,800 incl. some accessories, $26,000. Process Engineers 29 liter mammalian cell bioreactor, new/unused, ~$35,000 or best offer. *Too hard to classify:     PE 9600 thermocyclers: $4,500 guaranteed working     PE 480 thermocyclers: $3,000 guaranteed working; have several     MD Fluorimager SI, 1995 model, $14,500     MD Cytosensor, ~ 50% of new price     PerSeptive Cytofluor II, ~1997, was $20,000 new; virtually unused; $12,500     Perkin Elmer LS-50B luminescence spectrophotometer w/ plate reader upgrade, WINLab software; $12,500; plate reader = + $6,000     ABI Catalyst 877 turbo, $13,000     PerSeptive Cytofluor II, ~1997, virtually unused, ~$12,000     Tekne Geneous PCR machines, 1 yr old, have 2, $1,750 ea. *Service: We rebuild valve blocks for ABI 430, 431 and 39x @ $65/port, 90-day warranty Service and contracts on ABI 39n and PerSeptive 8909/8905s available. Service contracts on Hewlett Packard HPLCs, GCs and MSs available at a savings over HP rates *Also available: HPLCs, ICs, CEs, FPLCs: microbore to prep scale Beckman, Tecan, Hamilton robots/liquid handlers A variety of other lab instruments     Please call or email with your request. Michael Sherrell Grizzly Analytical (USA) 707 887 2919/fax 707 887 9834 www.grizzlyanalytical.com --- From owner-molreps@hgmp.mrc.ac.uk Tue Mar 14 10:56:44 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 45F2517B01; Tue, 14 Mar 2000 10:56:43 +0000 (GMT) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 1) id 5CD2117A8D; Tue, 14 Mar 2000 10:56:38 +0000 (GMT) To: molreps@net.bio.net Newsgroups: bionet.molecules.repertoires From: Guenter Grethe Subject: REMINDER -- REMINDER ------ CALL FOR PAPERS-PACIFICHEM2000 Date: 14 Mar 2000 08:56:06 -0000 Organization: BIOSCI/MRC Human Genome Mapping Project Resource Centre Message-ID: <8E13FBBA26A9DA119ED400A0C9AB2CE502F33BCF@shepherd.mdli.com> Sender: owner-molreps@hgmp.mrc.ac.uk Precedence: bulk The co-organizers of the symposium 'Use of Chemical Information in Organic Synthesis' at Pacifichem2000 in Honolulu are asking you again to consider contributing a paper to this important symposium. Several eminent scientists working in this area of reasearch have already accepted an invitation to present a talk. The original 'Call for Papers' follows below. We are especially encouraging young scientist to apply for 'Travel Grants for Young Chemistry Scholars'. Please check http://www.acs.org/meetings/pacific2000/tgrants.html for details. The following Call for Papers has been listed on several servers, I apologize for any duplication. CALL FOR PAPERS The 2000 International Chemical Congress of Pacific Basin Societies will take place in Honolulu, Hawaii, from December 14 - 19, 2000. The congress is cosponsored by the American Chemical Society , the Chemical Society of Japan, the Canadian Society for Chemistry, the New Zealand Institute of Chemistry and the Royal Australian Chemical Institute. Chemical Societies in the countries that border the Pacific Ocean will be Official Participating Organizations. Overall, 6,000 reports on current research and development will be presented in 179 symposia and in oral and poster general sessions in 10 topical areas. If previous congresses are any indication, this year's program should be highly interesting and attendance should be very large. You are invited to submit an abstract for a paper or poster to be considered for presentation at symposium #175 "Use of Chemical Information in Organic Synthesis", co-organized by Prof. Kimito Funatsu, Toyohashi University of Technology, Japan, Dr. David Winkler, CSRIO Division of Molecular Science, Australia, and Dr. Guenter Grethe, MDL Information Systems, Inc., USA. Abstracts of approximately 150 words must be submitted to the Congress Secretariat at ACS by April 3, 2000, for paper versions, or April 14 electronically. The congress abstract form is available for electronic retrieval and submission from the Pacifichem 2000 web site at http://www.acs.org/meetings/pacific2000 Paper forms can be obtained by contacting the Congress Secretariat at Pacifichem Congress Secretariat American Chemical Society 1155-16th S., N.W. Washington, DC 20036, USA e-mail: pacifichem@acs.org To encourage attendance at the congress by young chemistry professionals from developing countries that border the Pacific Ocean, the sponsoring societies of Pacifichem 2000 are making available up to 40 grants of $1,000 (U.S.) plus complimentary registration to assist with travel and attendance costs. Details about the scholarship are to be found on the congress web site. Why is participation in this symposium essential for synthetic chemists and information specialists? During the last two decades various programs and databases, large comprehensive and smaller thematic ones, covering a broad range of synthetic chemistry, have been developed to assist synthetic chemists with their tasks. Additionally, these databases have the potential to serve as a rich source for extracting data into knowledge bases for reaction planning and reaction prediction programs. Speakers at the symposium will address issues important to the various areas of reaction information management, such as synthesis planning, reaction retrieval and prediction, reagent selection, integrated web-based information, information needs in combinatorial chemistry, database generation and management, and other related topics. Emphasis of the symposium will be on the integration of various programs and data from multiple sources to simulate the working habits of synthetic chemists in gathering necessary information, thereby generating an environment in which they will use electronic tools comfortably and efficiently - the synthetic workbench of the future. Papers describing the use of the various tools and information sources available to synthetic chemists and information specialists alike are solicited. Presentations for contributed papers will be restricted to 25 minutes, including 5 minutes for Q & A. Following is a description of some of the topics we hope to cover in the symposium: Reaction retrieval Retrieval of relevant information from existing databases to plan the synthesis of discrete compounds or libraries and to search for applicable methodologies and efficient functional group transformations is the most frequently used and therefore the most important part of any reaction information system. Presentations on available systems and associated applications to facilitate their use, the contents of available reaction databases, efficient management of large datasets, such as classification, post-search tools to manage large hitlists and other retrieval related topics are invited. Reaction prediction Reaction prediction plays an important role in synthesis, particularly in process development and combinatorial chemistry. Presentations addressing the use of available programs and the generation of knowledge bases from reaction databases to assist in the validation of reaction proposals in the planning process will be part of the symposium. Other topics for discussion are applications of methodologies to use physico-chemical parameters in predicting the outcome of reactions and the importance of functional group perception and their dependency on reaction conditions as criteria for reagent selection and automated synthesis. Synthesis planning Synthesis planning is experiencing rejuvenation, largely due to developments in combinatorial chemistry. Emphasis of programs has shifted from planning syntheses of complex molecules to generating efficient and economic preparations of libraries of compounds, frequently involving the use of solid-phase methodology. We invite speakers to discuss progress made in this important area as well as talk about validation procedures used in the planning process and methods to select viable starting materials. Combinatorial chemistry Combinatorial synthesis continues to have an immense impact on the developments in managing chemical information. Finding the most relevant methodologies, planning a library, and selecting the most viable reagents and solid supports are some of the important tasks to be carried out by the synthetic chemist. Presentations on these topics as well as discussions about the utilization of available information for automated synthesis and effective data management are desirable. Electronic workbench The future and success of using electronic information in synthesis is heavily dependent on the smooth integration of the required tools in an electronic workbench through friendly graphical interfaces and smooth operations. To guarantee good results, the workbench must provide easy access to large amounts of data in diversified databases - online and inhouse - and in electronic versions of the primary and secondary literature. The electronic labjournal must serve both as an archiving and registration tool. We are soliciting papers describing the use of any of these tools, particularly web-based applications. If you have any questions please contact any of the organizers at the addresses shown below: Dr. Guenter Grethe MDL Information Systems, Inc. 14600 Catalina Street San Leandro, CA 94577 (+1) 510-357-2222, ext. 1430 (voice) (+1) 510-614-3616 (fax) guenter@mdli.com Prof. Kimito Funatsu Department of Knowledge-Based Information Engineering Toyohashi University of Technology Tempaku, Toyohashi 441-8580 Japan (+81) 532-44-6879 (voice) (+81) 532-47-9315 (fax) funatsu@tutkie.tut.ac.jp Dr. David A. Winkler CSIRO Molecular Science Private Bag, Clayton South MDC 3169 Australia (+61) 3-9545-2477 (voice) (+61) 3-9545-2446 (fax) dave.winkler@mo9lsci.csiro.au Dr. Guenter Grethe Director, Scientific Applications Product Development MDL Information Systems, Inc. 14600 Catalina Street, CA 94577 Tel.: (+1) 510-357-2222 ext.1430 Fax: (1) 510-614-3616 e-mail: guenter@mdli.com --- From owner-molreps@hgmp.mrc.ac.uk Wed Mar 15 14:33:21 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 9EDAA17B0F; Wed, 15 Mar 2000 14:33:20 +0000 (GMT) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 1) id D46B217AEF; Wed, 15 Mar 2000 14:33:14 +0000 (GMT) To: molreps@net.bio.net Newsgroups: bionet.molecules.repertoires From: Asim Kumar Debnath Subject: collaboration Date: 14 Mar 2000 08:55:12 -0000 Organization: BIOSCI/MRC Human Genome Mapping Project Resource Centre Message-ID: <38BFFD76.F79008D7@nybc.org> Sender: owner-molreps@hgmp.mrc.ac.uk Precedence: bulk Hi! We are actively looking for collaboration with research groups who have non-proprietary drug-like small molecule libraries to screen in our newly developed rapid screening technique to identify drugs targeted to HIV-1 gp41 as entry inhibitors. As some of you know we are very active in this area and recently received NIH funding for this research. We also have more than 12 years expertise in structure-based drug design and related techniques. If you are interested in this endeavor, please contact me directly by e-mail or fax. We will discuss in detail about the collaboration related issues. I would like to apologize to all of you, if this e-mail is not suitable to post to this group. Thank you. Asim Debnath -- ======================================================================= *** *** **** Asim K. Debnath, Ph.D. **** Lindsley F. Kimball Research Institute **** *** The New York Blood Center **** **** 310 E 67 Th Street **** ** **** New York, NY 10021 **** **** **** Tel. (212) 570-3373 **** ** **** Fax. (212) 570-3299 **************** E-mail: adebnath@nybc.org ************** ======================================================================== --- From owner-molreps@hgmp.mrc.ac.uk Wed Mar 15 14:36:58 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id AA02417B11; Wed, 15 Mar 2000 14:36:57 +0000 (GMT) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 1) id 8FF6817B0F; Wed, 15 Mar 2000 14:36:54 +0000 (GMT) To: molreps@net.bio.net Newsgroups: bionet.molecules.repertoires From: mrc7@cam.ac.uk (Mike Clark) Subject: Therapeutic Antibodies Date: 15 Mar 2000 13:31:27 -0000 Organization: Cambridge University, Department of Pathology. Message-ID: Sender: owner-molreps@hgmp.mrc.ac.uk Precedence: bulk Hi, I am an academic with a long history and a strong interest in the field of therapeutic antibodies. You may be aware of my web site Mike's Immunoglobulin Structure and Function Home Page http://www.path.cam.ac.uk/~mrc7/mikeimages.html The reason for this posting is that I would like to bring to your attention a new initiative on my website and also if possible ask for your assistance. The new initiative is called the 'Therapeutic Antibody Human Homology Project' You can find the main web pages as http://www.path.cam.ac.uk/~mrc7/humanisation/TAHHP.html and an introduction to why I started it at http://www.path.cam.ac.uk/~mrc7/humanisation/index.html How can you help? This project requires that I identify the correct sequences which go along with each therapeutic antibody. Unfortunately most antibodies go through multiple name changes during their commercial development. This makes it rather time consuming to track the antibodies currently in trials back to the description of their original sequences. However if you are able to point me to details of a therapeutic antibody and it's sequence I will endeavour to include it in the list. Please remember that I only wish to include sequences and data which is in the public domain and readily verifiable as such. Also of value would be published details of antiglobulin responses to these antibodies and I will eventually try to cross reference this data. I hope this project will prove to be of use in trying to interpret the data arising from the steadily increasing numbers of therapeutic immunoglobulins in clinical trials. My summary of results will of course be made available in the public domain. Cheers, Mike -- o/ \\ // || ,_ o M.R. Clark, PhD. Division of Immunology <\__,\\ // __o || / /\, Cambridge University, Dept. Pathology "> || _`\<,_ // \\ \> | Tennis Court Rd., Cambridge CB2 1QP ` || (_)/ (_) // \\ \_ Tel.+44 1223 333705 Fax.+44 1223 333875 --- From owner-molreps@hgmp.mrc.ac.uk Thu Mar 23 09:31:37 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 0A31617B82; Thu, 23 Mar 2000 09:31:35 +0000 (GMT) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 1) id AA8E617A81; Thu, 23 Mar 2000 09:31:34 +0000 (GMT) To: molreps@net.bio.net Newsgroups: bionet.molecules.repertoires From: mrc7@cam.ac.uk (Mike Clark) Subject: Therapeutic Antibody Human Homology Project Date: 21 Mar 2000 19:33:11 -0000 Organization: Cambridge University, Department of Pathology. Message-ID: Sender: owner-molreps@hgmp.mrc.ac.uk Precedence: bulk I have just uploaded some more pages to my web site. The pages concern my recently announced Therapeutic Antibody Human Homology Project. In particular I have compiled a list of therapeutic antibodies currently in clinical trials or approved by the FDA. http://www.path.cam.ac.uk/~mrc7/humanisation/antibodies.html I would love to trace these antibodies back to their original descriptions and sequences if possible. If you can help speed up the process please let me know either by email or if you wish by posting to this group. Thanks, Mike Clark, -- o/ \\ // || ,_ o M.R. Clark, PhD. Division of Immunology <\__,\\ // __o || / /\, Cambridge University, Dept. Pathology "> || _`\<,_ // \\ \> | Tennis Court Rd., Cambridge CB2 1QP ` || (_)/ (_) // \\ \_ Tel.+44 1223 333705 Fax.+44 1223 333875 --- From owner-molreps@hgmp.mrc.ac.uk Thu Mar 23 16:46:11 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 90F4817B66; Thu, 23 Mar 2000 16:46:10 +0000 (GMT) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 1) id 68B3317AB4; Thu, 23 Mar 2000 16:46:08 +0000 (GMT) To: molreps@net.bio.net Newsgroups: bionet.molecules.repertoires From: Dori Luzbetak Subject: Announcements from MDL Information Systems, Inc. Date: 23 Mar 2000 09:33:34 -0000 Organization: BIOSCI/MRC Human Genome Mapping Project Resource Centre Message-ID: <8E13FBBA26A9DA119ED400A0C9AB2CE50324617B@shepherd.mdli.com> Sender: owner-molreps@hgmp.mrc.ac.uk Precedence: bulk FROM: MDL Information Systems, Inc. http://www.mdli.com or http://www.mdli.co.uk MDL Information Systems, Inc. recently made several announcements that may be of interest to you. Be sure to regularly check WHAT'S NEW and EVENTS on our home page for the latest news about MDL. * See MDL at ACS San Francisco * ISIS/Direct - Chemically Intelligent Data Cartridge * LitLink/Pro Server - FREE Demo Offered * Toxicity and EcoPharm Databases Released * Chime Pro 2.5 - JavaBean Component Added * MDL Ports to Sun Solaris * PBS's NOVA Online Uses Chime for "Hot Science" * FREE Software & Support ================================================== SEE MDL AT ACS SAN FRANCISCO ================================================== MDL and Beilstein are exhibiting in Booth 1112 at the ACS Meeting & Exposition March 26-30 in San Francisco. MDL is also giving three presentations at the Division of Chemical Information (CINF) symposium. For more information, go to: http://www.mdli.com/cgi/dynamic/events.html?uid=&key=&id=15 ================================================== ISIS/DIRECT: CHEMICALLY INTELLIGENT DATA CARTRIDGE ================================================== MDL announced the release of ISIS/Direct, a data cartridge that enables research organizations to search chemical data and structures inside Oracle8i databases. For more information, go to: http://www.mdli.com/cgi/dynamic/whatsnew.html?uid=&key=&id=15 ================================================== LITLINK/PRO SERVER FREE DEMO OFFERED ================================================== The future of citation linking is here! LitLink/Pro Server, the latest innovation from MDL, links from citations in your Windows, Web, or Java applications to internal and third-party sources for journal articles, patents, reports, and proprietary documents. Go to http://www.litlink.com for a FREE interactive demo of LitLink/Pro Server. ================================================== TOXICITY AND ECOPHARM DATABASES RELEASED ================================================== MDL and Beilstein announced the release of two new databases, Toxicity and CrossFire EcoPharm. Toxicity provides in-depth coverage of over 145,000 chemical substances. CrossFire EcoPharm surveys pharmacological, toxicological, and ecological data from 180 leading journals. For more information, go to: http://www.mdli.com/cgi/dynamic/whatsnew.html?uid=&key=&id=2 ================================================== CHIME PRO 2.5 - JAVABEAN COMPONENT ADDED ================================================== MDL announced an extension to its popular plug-in for platform-independent chemical structure visualization and database searching. Chime Pro 2.5 adds a JavaBean component to the software's existing HTML-based tools, enabling developers to provide chemical structure rendering and visualization in pure Java applications and applets as well as in Web pages. For more information, go to: http://www.mdli.com/cgi/dynamic/whatsnew.html?uid=&key=&id=27 ================================================== MDL PORTS TO SUN SOLARIS ================================================== MDL announced the release of its core chemical information management server software on Sun servers running the Solaris 7 operating system. MDL has released ISIS/Host, Chemscape Server, and ISIS/Direct on Sun. Other server products will be released later this year. For more information, go to: http://www.mdli.com/cgi/dynamic/whatsnew.html?uid=&key=&id=28 ================================================== PBS's NOVA ONLINE USES CHIME FOR "HOT SCIENCE" ================================================== NOVA Online, the companion Web site to the popular PBS science program, is using MDL's free Chime plug-in for their "Hot Science" feature on diamonds. "Hot Science" enables you to explore the world of science via the Internet. Download Chime at http://www.mdli.com/download and try some "Hot Science" on NOVA Online at http://www.pbs.org/wgbh/nova/diamond/inside.html ================================================== FREE SOFTWARE & SUPPORT ================================================== Go to: http://www.mdli.com/download Chime - Chemical structure plug-in to render and view "live" 2D and 3D chemical structures within a Web page ISIS/Draw - Chemical drawing package with chemical intelligence (ISIS/Draw is free for academic and personal home use only.) Chime technical support http://www.mdli.com/support/chime/default.html ================================================== Questions? Send an email to info@mdli.com. #### Dori Luzbetak Web Communications Manager MDL Information Systems, Inc. 14600 Catalina Street San Leandro, CA 94577 --- From owner-molreps@hgmp.mrc.ac.uk Thu Mar 23 16:48:24 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 99ECB17B75; Thu, 23 Mar 2000 16:48:23 +0000 (GMT) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 1) id 0466B17B66; Thu, 23 Mar 2000 16:48:21 +0000 (GMT) To: molreps@net.bio.net Newsgroups: bionet.molecules.repertoires From: Steve Heller Subject: ChemInt2000 Workshops Date: 23 Mar 2000 09:29:40 -0000 Organization: BIOSCI/MRC Human Genome Mapping Project Resource Centre Message-ID: Sender: owner-molreps@hgmp.mrc.ac.uk Precedence: bulk This note is to announce that three workshops have been arranged as part of the ChemInt2000 meeting program. These will be workshops by MDL, ACD, and SciVision. The ChemInt2000 meeting web Abstract Submission form is operational for the Chemistry and the Internet (ChemInt2000) meeting being held in at Georgetown University in Washington DC on September 23-26, 2000. The draft program of invited speakers, workshops, markup langauge tutorial, and panel sessions (one on e-commerce chaired by Wendy Warr and one on Intranets and Internets chaired by Tom Pierce) is available on the meeting web site: http://www.chemint.org You are urged to look at the program and to consider submitting a poster paper to the meeting. Some 8-10 of poster papers will be selected for oral presentation at the meeting. The main lecturers for the meeting will be: Rene DePlanque, FIZ - Berlin Jim Myers, Pacific Northwest Labs Glen Hopkinson, Synopsys Scientific Systems Wolf-Dietrich Ihlenfeldt, University of Erlangen-Nurenberg Miloslav Nic, ICT Prague Jim Ostell, NIH/NLM/NCBI Engelbert Zass, ETH Henry Rzepa, Imperial College, London Peter Murray-Rust, Nottingham University Technical Sponsors are: ACS CINF Division ACS COMP Division The Chemical Structure Association (CSA) Georgetown University - Department of Chemistry Special Libraries Association (SLA) Chemistry Division Royal Society of Chemistry (RSC) Steve Heller Steve Heller, Guest Researcher NIST/SRD, Mail Stop: 820/113 820 Diamond Avenue, Room 101 Gaithersburg, MD 20899-2310 USA E-mail: chem@feldmann.nist.gov --- From owner-molreps@hgmp.mrc.ac.uk Wed Mar 29 10:01:44 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 64C2817B5C; Wed, 29 Mar 2000 10:01:43 +0100 (BST) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 1) id 4788917A6A; Wed, 29 Mar 2000 10:01:40 +0100 (BST) To: molreps@net.bio.net Newsgroups: bionet.molecules.repertoires From: Shu-Kun Lin Subject: MOLECULES and other online-only chemistry journals are promising Date: 29 Mar 2000 09:46:29 +0100 Organization: BIOSCI/MRC Human Genome Mapping Project Resource Centre Message-ID: <38DFCCF6.DAC0947B@mdpi.org> Sender: owner-molreps@hgmp.mrc.ac.uk Precedence: bulk (Excuse me for sending to several mailing lists) If one checks the online-only chemistry journals monitored by CAS (http://info.cas.org/EO/ejourn2.html) you would find that many of them have been able to publish only a small number of papers every year. Online journal editors, do not give up. MOLECULES now continuously publishes "thick" issues this year. Its vol.5 issue 3 (March 2000, pages 200-636) just released has 437 pages (http://www.mdpi.org/molecules/list00.htm#new). We publish many more papers recently and publish very quickly after peer reviewing procedure. (A long list of referees who helped evaluating manuscripts will be published soon.) Contributions of manuscripts are welcomed. I would like to acknowledge that this is the achievements of the Assistant Editor Dr. Derek J. McPhee (e-mail: mcphee@mdpi.org) who carefully and promptly handled many manuscripts, and the Production Editor Dr. Andrey Gutnov (e-mail: gutnov@mdpi.org), who did layout and final pdf files generation. Could you please help us by listing our journal MOLECULES (http://www.mdpi.org/molecules/) on your website and recommend it to your colleagues? Shu-Kun Lin Managing Editor, MOLECULES (ISSN 1420-3049) E-mail: lin@mdpi.org Dr. Shu-Kun Lin, President of MDPI Molecular Diversity Preservation International (MDPI) Saengergasse 25, CH-4054 Basel, Switzerland Tel. +41 79 322 3379, Fax +41 61 302 8918 E-mail: lin@mdpi.org http://www.mdpi.org/lin/ --- From owner-molreps@hgmp.mrc.ac.uk Wed Mar 29 10:40:01 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 9813C17B60; Wed, 29 Mar 2000 10:40:00 +0100 (BST) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 1) id 3399D17B5C; Wed, 29 Mar 2000 10:39:58 +0100 (BST) To: molreps@net.bio.net Newsgroups: bionet.molecules.repertoires From: Shu-Kun Lin Subject: MDPI news release: Int. J. Mol. Sci. (http://www.mdpi.org/ijms/) Vol. 1, 2000 Date: 29 Mar 2000 10:31:25 +0100 Organization: BIOSCI/MRC Human Genome Mapping Project Resource Centre Message-ID: <38E1C775.4D5A26C5@mdpi.org> Sender: owner-molreps@hgmp.mrc.ac.uk Precedence: bulk (Exculse me for sending to many mailing lists) MDPI launched one more new journal International Journal of Molecular Sciences (ISSN 1422-0067) at the http://www.mdpi.org/ijms website. The background regarding IJMS is at http://www.mdpi.org/ijms/htm/i1010003.htm. Access to the IJMS online edition is FREE. Please obtain your free and unique userID and password from ijms_request@mdpi.org (put "free subscription" as the subject title and your name and address in the text of your e-mail). A "Call for Papers to the IJMS" message as a pdf can be downloaded at http://www.mdpi.org/ijms/ijmsadvert.pdf. Shu-Kun -- Dr. Shu-Kun Lin Molecular Diversity Preservation International (MDPI) Saengergasse 25, CH-4054 Basel, Switzerland Tel. +41 79 322 3379, Fax +41 61 302 8918 E-mail: lin@mdpi.org http://www.mdpi.org/lin/ ---