From owner-neuroscience@net.bio.net Mon Aug 01 23:00:00 1994 Path: biosci!agate!msuinfo!harbinger.cc.monash.edu.au!yarrina.connect.com.au!werple.apana.org.au!news From: ferrett@werple.apana.org.au (Peter Berrett) Newsgroups: bionet.neuroscience Subject: Help - alpha waves...!!! Date: 3 Aug 1994 01:40:35 +1000 Organization: werple public-access unix, Melbourne Lines: 18 Message-ID: <31lpdj$8th@werple.apana.org.au> NNTP-Posting-Host: werple.apana.org.au Dear all, I saw a program 'The big byte' today which talked about how scientists have discovered a method of improving a persons intelligence, reading skills and concentration by visual and aural feedback from their brain waves. I only caught the tail end of the program but it looked intriguing. It seemed to work by measuring a person's alpha wave(s) and examining the extent to which it is unbalanced and then providing feedback so that people can 'train' their minds to respond more positively. Does anyone know anything further about this? It was also mentioned that nayone with a 386 could use this computer program to 'train' their minds better. Hoping someone can help. Cheers Peter From owner-neuroscience@net.bio.net Mon Aug 01 23:00:00 1994 Path: biosci!agate!msuinfo!netnews.upenn.edu!pender.ee.upenn.edu!avi From: avi@ee.upenn.edu (Avi Freedman) Newsgroups: bionet.neuroscience Subject: Molecular Biologist seeking a postdoc position Date: 2 Aug 1994 14:55:11 GMT Organization: University of Pennsylvania Lines: 33 Message-ID: <31lmof$795@netnews.upenn.edu> NNTP-Posting-Host: pender.ee.upenn.edu X-Newsreader: TIN [version 1.2 PL2] This post is for a friend: I have recently submitted my thesis. During my study I have dissected positive and negative regulatory elements in the 3 non-coding region of a human gene (uPA). For that I have used cell tissue culture and techniques of molecular biology: cloning, construction and manipulation of DNA constructs, transfection of of DNA into cells, PCR, Southern and Northern hybridization and RNase protection. I am also familiar with method of enzymology, protein purification, affinity chromatogra phy and HPLC, which I used during my M.Sc study. I am looking for a post-doc position in one of the following fields: regulation of gene expression, signal transduction pathways and molecular research in neurobiology. Interested persons are requested to contact: Yoel Smicun, Department of Biocemistry, Weizmann Institute of Science, ISRAEL. e-mail: bcsmicun@weizmann.weizmann.ac.il Ph: 972-8-342733, -343205 Fax: 972-8-344118 Curriculum vitae and a list of referees will be mailed to the interested persons. From owner-neuroscience@net.bio.net Mon Aug 01 23:00:00 1994 Newsgroups: bionet.neuroscience Path: biosci!bcm!news.msfc.nasa.gov!europa.eng.gtefsd.com!gatech!swrinde!elroy.jpl.nasa.gov!usc!nic-nac.CSU.net!charnel.ecst.csuchico.edu!olivea!uunet!hearst.acc.Virginia.EDU!liberty!lorigt From: lorigt@liberty.uc.wlu.edu (Tyler Lorig) Subject: Re: Home built EEG Message-ID: <1994Aug2.232336.8249@liberty.uc.wlu.edu> Date: Tue, 2 Aug 1994 23:23:36 GMT References: <318l98$l7t@vixen.cso.uiuc.edu> Organization: Washington & Lee University X-Newsreader: TIN [version 1.2 PL2] Lines: 21 Kevin Spencer (kspencer@iti.org) wrote: : sjacobs@maroon.tc.umn.edu (Steve Jacobson) writes: : >I am building an EEG machine and intend to digitize the amplified analog signals for input into a : >computer. I am considering using a 16 bit A/D for each channel. The question I have is: Is a 16 : >bit A/D overkill? Is 12 bits sufficient. What kind of voltage range am I liable to encounter on : >the EEG electrodes? I intend to use isolation devices between the front-end : >processor and the main computer. : >Any advice would be appreciated. : 12 bits is plenty for good amplitude resolution. I'd say the voltage : range of raw scalp-recorded EEG would be +/- 1000 uV. (Just a guess, : since I study ERPs and seldom look at unfiltered single trials of EEG.) : ----------------------------------------------------------- : Kevin Spencer : Cognitive Psychophysiology Laboratory and Beckman Institute : University of Illinois at Urbana-Champaign : kspencer@p300.cpl.uiuc.edu / kspencer@psych.uiuc.edu : ----------------------------------------------------------- From owner-neuroscience@net.bio.net Mon Aug 01 23:00:00 1994 Path: biosci!galaxy.ucr.edu!ihnp4.ucsd.edu!munnari.oz.au!newsroom.utas.edu.au!Dallas.Grasby@path.utas.edu.au From: Dallas.Grasby@path.utas.edu.au (Dallas Grasby) Newsgroups: bionet.neuroscience Subject: Dolphin sleep Date: 30 Jul 1994 03:51:58 GMT Organization: University of Tasmania Lines: 50 Distribution: world Message-ID: <31ciov$1oa@franklin.cc.utas.edu.au> NNTP-Posting-Host: clinicals101h70.med.utas.edu.au The study of sleep in the marine mammals is a fascinating area of comparative sleep physiology. Cetaceans, such as dolphins and whales (also the order Sirenia or sea cows), must regularly come to the turbulent ocean surface to respire - this requires strict maintenance of posture, muscle tone and reflectory activity. Because hypotonia and hyporeflexia are impermissable conditions for Cetacean sleep, the two hemispheres must enter the state of delta sleep alternately; always leaving one hemisphere to maintain tone and reflex to prevent inhalation of water. In fact, paradoxical sleep (associated with an even greater degree of hyporeflexia and hypotonia) appears to be totally absent in Cetaceans. The Pinnipeds (seals) are fundamentally different in that they can live and sleep in both terrestrial and marine environments. Seals can sleep on land, floating on the water surface or underwater, in the latter case however, they must regularly wake and come to the surface for respiration periods. Unlike Cetaceans, they do demonstrate paradoxical sleep and only some (such as the northern fur seal but not the Caspian seals) exhibit unihemispheric sleep. This difference is a reflection of the fact that seals have considerable adaptations for both terrestrial and marine environs. The neurophysiological mechanisms for unihemispheric sleep are unclear. Dolphins have a relatively small corpus callosum although it is thought that this factor is of little consequence. In other mammals (such as the Opossum), the absence of a true corpus callosum is associated with obligatory unihemispheric sleep, just as is invariably displayed in split-brain preparations of any species. The Cetacean brain offers unique opportunities to study aspects of sleep deprivation. Many interesting insights into sleep physiology have been provided by such research including the observation that absence of sleep in one hemisphere is not compensated for by prolonged periods of sleep in the other. Much of this work has been done by Mukhametov (with many of the reports available only in russian) but for an interesting, albeit 'older' reference I direct you to: Mukhametov, L.M. (1984) Sleep in Marine Mammals. Experimental Brain Research. Supplement 8. Berlin: Springer-Verlag. pp 227-238. also- Mukhametov, L.M., Supin, A.Y., and Polyakova, I.G. (1977) Interhemispheric asymmetry of the electroencephalographic sleep patterns in dolphins. Brain Research 134: 581-584. I was interested to note that some correspondents to bionet.neuroscience mentioned unihemispheric in birds. I would be most interested in any references to studies of this kind - or indeed any recent references with relevance to the topic in general (including work with marine mammals). Dallas.Grasby@path.utas.edu.au From owner-neuroscience@net.bio.net Mon Aug 01 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!gatech!newsfeed.pitt.edu!uunet!newstf01.cr1.aol.com!search01.news.aol.com!not-for-mail From: lizlloyd@aol.com (Liz Lloyd) Newsgroups: bionet.neuroscience Subject: Re: grad schools Date: 2 Aug 1994 17:42:10 -0400 Organization: America Online, Inc. (1-800-827-6364) Lines: 29 Sender: news@search01.news.aol.com Message-ID: <31meji$lph@search01.news.aol.com> References: <2rogha$365@news.bu.edu> NNTP-Posting-Host: search01.news.aol.com In article <2rogha$365@news.bu.edu>, tholeva@bu.edu (Thomas Holeva) writes: >Concerning Thomas' comments about depression/helping students I had a very similar depression experience in undergraduate school that I believe has been my major motivation for getting a higher degree with the ultimate purpose of helping people. Like you, my depression was unrecoginized and I got no compassion nor help from my professors. Now I am into my third year of a PhD program in Neuroscience at Bowman Gray School of Medicine, Wake Forest Univ., Winston-Salem, NC. I enjoy research, but I don't live for it. My ultimate goal is to be a damn good teaching and advising professor. From your message, you sound motivated to help people either through clinical or teaching work. My brief advice to you is: 1. The most important thing in grad school is to have a good relationship with your advisor. I have seen highly intelligent, motivated people stopped short of their goals because of incompassionate, asshole advisors. Good advisors are hard to come by. 2. I suggest that if you decide to go PhD with hopes of teaching instead of MD, go to an undergraduate institution instead of a medical school. Medical schools tend to look down on teaching and discourage it. It is a constant, uphill battle for me to get teaching experience in the medical school. 3. Keep your "humanness". I have been in science for many years and have seen scientists put their work number one and everything else number two. You don't have to conform to this in order to be successful. Good luck. You sound like you have all the right reasons for going on. Liz Lloyd From owner-neuroscience@net.bio.net Mon Aug 01 23:00:00 1994 Path: biosci!agate!usenet From: Joseph_Pullara@Maillink.berkeley.edu (Joe) Newsgroups: bionet.neuroscience Subject: Re: Dolphin sleep Date: 2 Aug 1994 21:34:35 GMT Organization: UC Berkeley Lines: 15 Sender: -Not-Authenticated-[2536] Message-ID: <31me5b$m50@agate.berkeley.edu> References: <31ciov$1oa@franklin.cc.utas.edu.au> NNTP-Posting-Host: gpbt1mac28.berkeley.edu X-Posted-From: InterNews 1.0.1b23@gpbt1mac28.berkeley.edu Xdisclaimer: No attempt was made to authenticate the sender's name. In article <31ciov$1oa@franklin.cc.utas.edu.au> Dallas.Grasby@path.utas.edu.au (Dallas Grasby) writes: > > The study of sleep in the marine mammals is a fascinating area of comparative sleep.... (lots deleted) Great post! Any info on how many hours in a 24 hr period Cetaceans spend in this alternating unihemispheric delta sleep? I know I could look up the references but I'm lazy :-) - Joe Pullara UC Berkeley From owner-neuroscience@net.bio.net Mon Aug 01 23:00:00 1994 Path: biosci!bcm!SPECIALK.IAIMS.BCM.TMC.EDU!ak990140 From: ak990140@SPECIALK.IAIMS.BCM.TMC.EDU (Artur Kania) Newsgroups: bionet.neuroscience Subject: Re: Shaking hands during dissections Date: 2 Aug 1994 18:20:07 GMT Organization: Baylor College of Medicine, Houston, Tx Lines: 19 Sender: ak990140@SPECIALK.IAIMS.BCM.TMC.EDU (Arthur Kania) Distribution: world Message-ID: <31m2on$c5m@gazette.bcm.tmc.edu> References: <31f0r9$jsq@nntp2.Stanford.EDU> <31gbov$16k@search01.news.aol.com> <31jtb6$l9t@lyra.csx.cam.ac.uk> NNTP-Posting-Host: specialk.iaims.bcm.tmc.edu In article <31jtb6$l9t@lyra.csx.cam.ac.uk>, mhe1000@cus.cam.ac.uk (Dr M.H. Evans) writes: |> In article <31gbov$16k@search01.news.aol.com>, |> NigelCoop wrote: |> >In article <31f0r9$jsq@nntp2.Stanford.EDU>, rasch@leland.Stanford.EDU |> >(Christopher Michael Rasch) writes: "cannot dissect due to shaky hands" |> > I frequently dissect Drosophila embryos without any micromanipulators (under a dissecting scope of course), I find that a couple of strong beers before dissecting usually do the trick. Really . -- Artur Kania Department of Molecular and Human Genetics Howard Hughes Medical Institute Baylor College of Medicine Houston, TX USA From owner-neuroscience@net.bio.net Mon Aug 01 23:00:00 1994 Newsgroups: bionet.neuroscience Path: biosci!agate!spool.mu.edu!sdd.hp.com!decwrl!decwrl!netcomsv!netcom.com!starin From: starin@netcom.com (Jeffrey Starin) Subject: corpus collosum Message-ID: Organization: NETCOM On-line Communication Services (408 261-4700 guest) X-Newsreader: TIN [version 1.2 PL1] Date: Tue, 2 Aug 1994 02:52:39 GMT Lines: 17 Well, I hope this is the correct group to post this question. First off, I am *not* a neuro-scientist, rather, a writer. I am writing a story about an individual who has his corpus collosum severed in an attempt to curtail his epileptic seizures. I was told that this operation was performed, but then stopped. My question is really this: I need to know of an operation that could be performed on an indivual which would result in them losing the ability to dream, or remember their dreams. I was told once that the aforementioned operation resulted in loss of dream recall. Is that so? I also need to know that if indeed someone actually loses the ability to dream, would they go crazy? Insane? Any help much appreciated. Jeffrey {New York} -- Jeffrey {New York} From owner-neuroscience@net.bio.net Tue Aug 02 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!usc!sdd.hp.com!col.hp.com!dana From: dana@col.hp.com (Dana Johnson) Newsgroups: bionet.neuroscience Subject: How can I get info on ataxia? Date: 3 Aug 1994 07:08:09 GMT Organization: HP Colorado Springs Division Lines: 19 Message-ID: <31nfop$20c@hp-col.col.hp.com> NNTP-Posting-Host: alien8.col.hp.com X-Newsreader: TIN [version 1.2 PL2] Hi, Could someone please give me advice about how to get information about ataxia via the internet? A friend has asked me to see what might be available. So far I have found reference to Medline, which if I understand correctly, is a means to obtain journal references by subject. Any and all info would be greatly appreciated! dana ------------------------------------------------------------------------------ Dana Johnson Hewlett-Packard Company Email: dana@col.hp.com 1900 Garden of the Gods Road Phone: 719-590-2136 Colorado Springs, CO 80901-2197 Fax: 719-590-2251 From owner-neuroscience@net.bio.net Tue Aug 02 23:00:00 1994 Path: biosci!daresbury!trane.uninett.no!eunet.no!nuug!EU.net!uunet!newsflash.concordia.ca!altitude!Megot!dan From: dan@pmt.qc.ca (Daniel Savard) Newsgroups: bionet.neuroscience Subject: Maladie neuro-musculaire inconnu? Date: 3 Aug 1994 02:39:49 GMT Organization: PMT Video ltee Montreal, Quebec Canada Lines: 57 Message-ID: <31n01l$aej@Tandem.CAM.ORG> NNTP-Posting-Host: pmt-gw.cam.org X-Newsreader: TIN [version 1.2 PL0] X-Newsreader: TIN [version 1.2 PL0] Bonjour, nous sommes a la recherche d'informations ou de pistes qui pourraient elucider le mystere concernant cette maladie supposement inconnu qui affecte notre fille. En effet, il semblerait qu'elle soit affectee d'une maladie neuro-musculaire possiblement d'origine genetique inconnue. Voici un bref appercu de son etat. Une deuxieme opinion serait grandement apreciee. Il s'agit d'une fillette de 2 ans qui est nee apres une grossesse normale sans difficulte. Elle affiche un retard moteur et presente des signes d'hypotonie marquee, predominant au niveau tronculaire, avec une instabilite tronculaire importante, compatible avec une ataxie axiale. On note egalement une certaine dysmetrie lors des mouvements des membres superieurs, les reflexes osteo-tendineux etant presents. Le retard moteur est devenu apparent vers l'age de 11 mois date a laquel nous avons consulte. A l'age de 2 ans, elle ne marche toujours pas, ne se tenant pas debout seule, par contre, au niveau de l'interet et du contact avec l'entourage, elle se developpe bien. Il existe aussi un retard au niveau de la parole. Un Rayon X de la colonne, un EEG et un scan cerebral ont ete fait et le Rayon X ainsi que le EEG se sont averes normaux. Parcontre sur le CT Scan cerebral, il a ete fait mention d'une hypoplasie vermienne. Une etude de vitesse de conduction et un electromyogramme montrent un leger raletissement des vitesses de conduction motrice au niveau des nerfs median et poplite externe. Un ammoniac, un acid lactique et un acid pyruvique sanguin se sont averes normaux, de meme qu'un astrup. Une evaluation en cardio et en ophtalmo, s'est averee negative. Une resonance magnetique cerebrale s'est aussi averee normale. Une biopsie musculaire n'a revelee rien d'anormal. Suite a une investigation faite a l'hopital Sainte-Justine, les medecins en viennent a soupconner une myopathie, qui pourrait etre de type mitochondrial. La courbe de croissance du perimetre cranien est en deceleration depuis la naissance. Elle est passee du 50ieme percentile au 2ieme percentile sur une periode d'un peu plus de 1 an. A partir de l'age de l'age de 16 mois, ce perimetre s'est mis a croitre pour la premiere fois. Desormais a l'age de 26 mois, elle peut s'asseoir sans support, se tenir debout avec appui et se deplacer a quatre pattes avec une base tres large. Son developpement mental semble normal et sa motricite fine au niveau des membres superieurs est celle d'un enfant de 18 mois. Vos opinions? Daniel Savard Dan@PMT.QC.CA From owner-neuroscience@net.bio.net Tue Aug 02 23:00:00 1994 Newsgroups: bionet.neuroscience Path: biosci!agate!howland.reston.ans.net!europa.eng.gtefsd.com!uhog.mit.edu!news.mtholyoke.edu!world!decwrl!netcomsv!netcom.com!starin From: starin@netcom.com (Jeffrey Starin) Subject: Need info Message-ID: Organization: NETCOM On-line Communication Services (408 261-4700 guest) X-Newsreader: TIN [version 1.2 PL1] Date: Tue, 2 Aug 1994 23:41:20 GMT Lines: 8 Does anyone know of some discussion groups or lists dealing specifically with sleep disorders? Jeffrey {New York} -- Jeffrey {New York} From owner-neuroscience@net.bio.net Tue Aug 02 23:00:00 1994 Newsgroups: bionet.neuroscience Path: biosci!agate!ames!elroy.jpl.nasa.gov!usc!howland.reston.ans.net!europa.eng.gtefsd.com!newsxfer.itd.umich.edu!uunet!hearst.acc.Virginia.EDU!murdoch!galen.med.Virginia.EDU!asa3h From: asa3h@galen.med.Virginia.EDU (Adam Stephen Arthur) Subject: Re: Dolphin sleep Message-ID: Sender: usenet@murdoch.acc.Virginia.EDU Organization: uva References: <31ciov$1oa@franklin.cc.utas.edu.au> Date: Wed, 3 Aug 1994 13:57:31 GMT Lines: 11 Thanks for the informative post. I believe the second of your references was the one that originally got me interested, starting this thread. I think its fabulous that one idiotic post here has turned into some truly intriguing info/speculation. While I am not completely certain of all the implications of "unihemisphereic sleep" I find it fascinating. Is there anything remotely like this documented in primates or humans, split-brained or otherwise? I would guess not... From owner-neuroscience@net.bio.net Tue Aug 02 23:00:00 1994 Path: biosci!bcm!news.msfc.nasa.gov!europa.eng.gtefsd.com!howland.reston.ans.net!newsserver.jvnc.net!yale.edu!news.ycc.yale.edu!kentfitz From: kentfitz@minerva.cis.yale.edu (Kent Fitzgerald (GD 1994)) Newsgroups: bionet.neuroscience Subject: Re: Shaking hands during dissections Date: 3 Aug 1994 18:01:15 GMT Organization: Yale University Lines: 23 Message-ID: <31om1b$e0n@news.ycc.yale.edu> References: <31f0r9$jsq@nntp2.Stanford.EDU> NNTP-Posting-Host: minerva.cis.yale.edu X-Newsreader: TIN [version 1.2 PL2] Chris, Try to eiminate any postural strain. If you're hunched over, stretching, or reaching, it's that much harder to keep steady. This means getting your chair, table and scope into the right positions so you're sitting upright and relaxed, with you forarms resting on the table and your feet flat on the ground. Good luck, Kent From owner-neuroscience@net.bio.net Tue Aug 02 23:00:00 1994 Newsgroups: bionet.neuroscience Path: biosci!agate!howland.reston.ans.net!newsserver.jvnc.net!news.caren.net!news.join.ad.jp!wnoc-tyo-news!news.u-tokyo.ac.jp!news.tisn.ad.jp!aist.go.jp!ripspost!b0017 From: b0017@nibh.go.jp (Maurizio MORABITO; Tel.6661) Subject: Tourette Syndrome Message-ID: Sender: news@aist.go.jp Nntp-Posting-Host: 150.29.56.34 Organization: National Institue of Bioscience and Human-Technology(NIBH), Japan. Date: Wed, 3 Aug 1994 04:31:49 GMT Lines: 10 Hi all! I am looking for refs about the Tourette Syndrome, particularly about the "coprolalia" (Dirty language) effect. Is there anybody that can help me please? thanks maurizio -- Maurizio Morabito maurizio@nibh.go.jp From owner-neuroscience@net.bio.net Wed Aug 03 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!europa.eng.gtefsd.com!newsxfer.itd.umich.edu!uunet!newsflash.concordia.ca!canopus.cc.umanitoba.ca!uwpg02.uwinnipeg.ca!wsimpsn2 From: wsimpsn2@uwpg02.uwinnipeg.ca Newsgroups: bionet.neuroscience Subject: crayfish neuroanatomy Date: 4 AUG 94 19:55:41 CST Organization: University of Winnipeg Lines: 8 Message-ID: <4AUG94.19554166@uwpg02.uwinnipeg.ca> NNTP-Posting-Host: uwpg02.uwinnipeg.ca Hello! For an undergrad physiological psych lab, we're planning on doing an invertebrate prep using crayfish. Nothing's definate yet, but we've kicked around ideas such as single cell recording, LTP induction, and electrolyte manipulations. Anyway, does anyone know of a lab manual of some sort dealing with crayfish neuroanatomy? Of particular intrest are neural networks/pathways for particular behaviours such as tail-flick. Your help is greatly appreciated. ~Aaron Newman wsimpsn2@uwpg02.uwinnipeg.ca From owner-neuroscience@net.bio.net Wed Aug 03 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!europa.eng.gtefsd.com!library.ucla.edu!news.mic.ucla.edu!news.bc.net!newsserver.sfu.ca!rs25-annex3.sfu.ca!twahl From: twahl@sfu.ca (Tom Wahl) Newsgroups: bionet.neuroscience Subject: Help - Computer Application Triggers Epileptic Reaction Date: Thu, 4 Aug 1994 13:03:48 Organization: Simon Fraser University Lines: 18 Message-ID: NNTP-Posting-Host: rs25-annex3.sfu.ca Summary: Rate of screen changes believed to cause epileptic reaction. Can anyone help? Keywords: epilepsy, epileptic, seizures, computer X-Newsreader: Trumpet for Windows [Version 1.0 Rev A] One of the staff where I work is having problems with her epilepsy during work sessions with a specific computer application. It appears that the rate at which the screen colours change triggers a seizure. However, we are unable to clearly determine the actual cause of the problem. We have attempted to eliminate as many potential variables as possible, but are well beyond the sphere of our expertise (being computer technicians, not medical experts). Does anyone know where I can find some information or help? Thanks, Tom +-----------+-------------------------+---------------------------+ | Tom Wahl | E-MAIL: twahl@sfu.ca | VOICE: (604) 876-6991 | +-----------+-------------------------+---------------------------+ | Hours at a computer can often save minutes of reading a manual. | +-----------------------------------------------------------------+ From owner-neuroscience@net.bio.net Wed Aug 03 23:00:00 1994 Path: biosci!agate!usenet.ins.cwru.edu!eff!news.duke.edu!godot.cc.duq.edu!newsfeed.pitt.edu!ache.pharm.pitt.edu!user From: drg@prophet.pharm.pitt.edu (Duke Groebe) Newsgroups: bionet.neuroscience Subject: Re: Shaking hands during dissections Followup-To: bionet.neuroscience Date: 4 Aug 1994 12:17:15 GMT Organization: University of Pittsburgh Lines: 20 Distribution: world Message-ID: References: <31f0r9$jsq@nntp2.Stanford.EDU> <31om1b$e0n@news.ycc.yale.edu> NNTP-Posting-Host: ache.pharm.pitt.edu In article <31om1b$e0n@news.ycc.yale.edu>, kentfitz@minerva.cis.yale.edu (Kent Fitzgerald (GD 1994)) wrote: > > Chris, Try to eiminate any postural strain. If you're hunched over, > stretching, or reaching, it's that much harder to keep steady. This means > getting your chair, table and scope into the right positions so you're > sitting upright and relaxed, with you forarms resting on the table and > your feet flat on the ground. Good luck, Kent You know. I make it a point never to shake hands during a dissection. Duke ****************************************************************************** The opinions expressed here are my own. MY very own and NOBODY else's! I THOUGHT OF THEM FIRST, HA HA, AND YOU DIDN'T!! SEE!? There's my name up there! And the date - Ooohh, the DATE! That's important! HEE HEE, I'M GONNA BE RICH! DO YOU HEAR ME!? RICH!! HA HA!! They're mine...heh, heh, all mine.... GOD! I'm so smart! From owner-neuroscience@net.bio.net Wed Aug 03 23:00:00 1994 Newsgroups: bionet.neuroscience Path: biosci!agate!usenet.ins.cwru.edu!news.ecn.bgu.edu!psuvax1!news.pop.psu.edu!news.cac.psu.edu!newsserver.jvnc.net!news.caren.net!news.join.ad.jp!wnoc-tyo-news!news.u-tokyo.ac.jp!news.tisn.ad.jp!aist.go.jp!ripspost!b0017 From: b0017@nibh.go.jp (Maurizio MORABITO; Tel.6661) Subject: Re: Tourette Syndrome In-Reply-To: Dennis Block's message of Wed, 3 Aug 94 20:23:24 -0500 Message-ID: Sender: news@aist.go.jp Nntp-Posting-Host: 150.29.56.34 Organization: National Institue of Bioscience and Human-Technology(NIBH), Japan. References: Date: Thu, 4 Aug 1994 07:34:24 GMT Lines: 17 In article Dennis Block writes: >Please read Dr. Cummings book on TS. He is an authority in the field. >He is based at the >City of Hope in Duarte, Ca. His first name is Bernard. My son also >has been diagnosed with ts but he does not display coprolalia. He tends >to have more obsessive, compulsive behavior. Is the person with ts >a member of your family ? No, I am posting for a friend that is interested in the influence of the surrounding culture on a person affected by TS. maurizio -- Maurizio Morabito maurizio@nibh.go.jp From owner-neuroscience@net.bio.net Wed Aug 03 23:00:00 1994 Path: biosci!VMS2.MACC.WISC.EDU!hxie From: hxie@VMS2.MACC.WISC.EDU ("huiwen xie") Newsgroups: bionet.neuroscience Subject: help needed Date: 3 Aug 1994 18:18:09 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 10 Sender: daemon@net.bio.net Distribution: world Message-ID: <72891.hxie@vms2.macc.wisc.edu> NNTP-Posting-Host: net.bio.net Does anyone in this net know where I can get some purified tetanus toxin for my experiments? I called Sigma, RBI, GIBCO, Boehringheim, and Calbichem. Only the last two carry tetanus toxin product. I don't know fragment C of tetanus toxin or tetanus toxin-recombinant can be used as neurotransmitter release inhibitor. Any help will be highly appreciated! Thanks in advance. Huiwen Xie Physiology UW-Madison From owner-neuroscience@net.bio.net Wed Aug 03 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!gatech!newsfeed.pitt.edu!uunet!news.delphi.com!usenet From: Dennis Block Newsgroups: bionet.neuroscience Subject: Re: Tourette Syndrome Date: Wed, 3 Aug 94 20:23:24 -0500 Organization: Delphi (info@delphi.com email, 800-695-4005 voice) Lines: 6 Message-ID: References: NNTP-Posting-Host: bos1d.delphi.com X-To: Maurizio MORABITO; Tel.6661 Please read Dr. Cummings book on TS. He is an authority in the field. He is based at the City of Hope in Duarte, Ca. His first name is Bernard. My son also has been diagnosed with ts but he does not display coprolalia. He tends to have more obsessive, compulsive behavior. Is the person with ts a member of your family ? From owner-neuroscience@net.bio.net Wed Aug 03 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!noc.near.net!usenet.uchc.edu!usenet From: barry@neuron.uchc.edu Newsgroups: bionet.neuroscience Subject: Re: European Minnow (Phoxinus phoxinus)? Date: 4 Aug 1994 19:17:39 GMT Organization: Univ of CT Health Center Lines: 12 Message-ID: <31resj$6ov@threed.uchc.edu> NNTP-Posting-Host: goat.uchc.edu In article <1994Jul26.170057.4146@news.yale.edu> senseman@fred.mbl.edu (David M. Senseman) writes: >I would like to conduct some physiological studies >on the European minnow, Phoxinus phoxinus. Does >anyone you of a source for these critters? > >Thanks! >No! Why not try aquarium news groups? Some importers of fish, ? European: Jerry Meola 201-343-5588 (African fish) , Merit, NJ 201-652-8808, I don't know how current these numbers are. Mike Barry From owner-neuroscience@net.bio.net Wed Aug 03 23:00:00 1994 Path: biosci!agate!spool.mu.edu!darwin.sura.net!nntp.msstate.edu!saimiri.primate.wisc.edu!news.doit.wisc.edu!news From: KIM@EPISAS.EPI.WISC.EDU (HYON KIM) Newsgroups: bionet.neuroscience Subject: Info on Multi-site neuro/sleep program Date: 4 Aug 1994 15:03:15 GMT Organization: PREVENTIVE MEDICINE Lines: 7 Distribution: world Message-ID: <31qvvj$re@news.doit.wisc.edu> NNTP-Posting-Host: episas.epi.wisc.edu X-News-Reader: VMS NEWS 1.24 I am interested in getting some feedback from currently enrolled students or graduates of the Multi-site training neuroscience/sleep medicine program sponsored by UCLA. I am applying for next year and personal experiences from the program are greatly appreciated(i.e., about anything). hk From owner-neuroscience@net.bio.net Wed Aug 03 23:00:00 1994 Path: biosci!agate!usenet From: Joseph_Pullara@Maillink.berkeley.edu (Joe) Newsgroups: bionet.neuroscience Subject: Re: crayfish neuroanatomy Date: 4 Aug 1994 22:32:44 GMT Organization: UC Berkeley Lines: 16 Sender: -Not-Authenticated-[2536] Message-ID: <31rqac$ivi@agate.berkeley.edu> References: <4AUG94.19554166@uwpg02.uwinnipeg.ca> NNTP-Posting-Host: gpbt1mac28.berkeley.edu X-Posted-From: InterNews 1.0.1b23@gpbt1mac28.berkeley.edu Xdisclaimer: No attempt was made to authenticate the sender's name. In article <4AUG94.19554166@uwpg02.uwinnipeg.ca> wsimpsn2@uwpg02.uwinnipeg.ca writes: > Anyway, does anyone know of a lab manual of some sort dealing > with crayfish neuroanatomy? E-mail me and I'll send you a copy of the manual and protocol we use in our undergraduate neurobiology lab course. Not really neuroanatomy though. Synaptic physiology of crayfish escape (tail flex). - Joe Pullara Joseph_Pullara@Maillink.berkeley.edu From owner-neuroscience@net.bio.net Wed Aug 03 23:00:00 1994 Path: biosci!IPRUNIV.CCE.UNIPR.IT!vetfisio From: vetfisio@IPRUNIV.CCE.UNIPR.IT Newsgroups: bionet.neuroscience Subject: VOLTAGE-SENSITIVE DYES Date: 4 Aug 1994 03:01:21 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 9 Sender: daemon@net.bio.net Distribution: world Message-ID: NNTP-Posting-Host: net.bio.net Could anyone help me in choosing the appropriate voltage sensitive probe for my experiments? I have to test the electrical activity of cultured mammalian olfactory neurons in response to different odorants. I have a fluorescent optic microscope with a connected camera, so I wonder if a fluorescent probe could be a good idea. Pino Silvestri Vetfisio@ipruniv.cce.unipr.it From owner-neuroscience@net.bio.net Wed Aug 03 23:00:00 1994 Path: biosci!bcm!news.msfc.nasa.gov!europa.eng.gtefsd.com!newsxfer.itd.umich.edu!news.itd.umich.edu!med.umich.edu!pwick From: pwick@med.umich.edu (Peter F. Wick) Newsgroups: bionet.neuroscience Subject: tetanus toxins Date: 4 Aug 1994 21:29:21 GMT Organization: University of Michigan - DMSV Lines: 10 Distribution: world Message-ID: <31rmjh$3gr@lastactionhero.rs.itd.umich.edu> NNTP-Posting-Host: renoir.dmsv.med.umich.edu Keywords: Huiwen Xie, have you contacted Dr. B. Das Gupta right in your own back yard? I work in a lab at the U of Mich that studies chromaffin cell biology. We have collaborated with Das Gupta concerning his botulinum toxin work and I think he and his coworkers also deal with tetanus toxins as well. I think he is in Food research facilities at the U of Wisconsin, maybe even at Madison but I'm not sure. Look up his name, as well as Bittner and Holz at the U of Mich. You could also scan the field of annexin research, especially synaptobrevin (VAMPs), synaptotagmin, syntaxins etc. Tetanus toxin's zinc-protease activity has been implicated in disrupting exocytosis but I am unsure just which fragments have been identified as responsible. Peter Wick Pharmacology UM Ann Arbor From owner-neuroscience@net.bio.net Thu Aug 04 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!gatech!newsfeed.pitt.edu!garnet.bns.pitt.edu!mana From: mana@bns.pitt.edu (Michael J. Mana) Newsgroups: bionet.neuroscience Subject: Re: Tourette Syndrome Date: Thu, 4 Aug 1994 20:37:38 Organization: University of Pittsburgh, Behavioral Neuroscience Lines: 11 Message-ID: References: NNTP-Posting-Host: garnet.bns.pitt.edu X-Newsreader: Trumpet for Windows [Version 1.0 Rev A] Advances in Neurology, Vol 58: Tourette's Syndrome: Genetics, Neurobiology, and Treatement. Eds. T.N. Chase, A.J. Freidhoff, and D.J. Cohen. NY: Raven Press, 1992. Handbook of TS and Related Tic and Behavioral Disorders, Ed, R. Kurlan. NY: Marcel Dekker, 1993. These books deal with much more than the coprolalia you are interested in, but should get your foot in the door... MJM From owner-neuroscience@net.bio.net Thu Aug 04 23:00:00 1994 Newsgroups: bionet.neuroscience Path: biosci!rutgers!gatech!howland.reston.ans.net!europa.eng.gtefsd.com!ceylon!news2.near.net!usenet.elf.com!rpi!news.columbia.edu!lamont!news From: larry@ljameson.bcsc.gov.bc.ca Subject: Help with Dystonia Message-ID: <1994Aug5.194527.27584@lamont.ldgo.columbia.edu> Summary: Looking for info re Dystonia Keywords: Dystonia Lines: 20 Sender: news@lamont.ldgo.columbia.edu Reply-To: larry@ljameson.bcsc.gov.bc.ca Organization: Lamont-Doherty Earth Observatory X-Newsreader: IBM NewsReader/2 v1.02 Date: Fri, 5 Aug 1994 19:45:27 GMT Several years ago I was diagnosed as having a movement disorder called dystonia. The specific disorder was spasmodic torticollis which causes my head to constantly turn to one side and makes it extremely difficult to turn the other direction or look straight ahead. In the last year or so the same disorder has also started to affect my voice making it difficult to speak and leaving me with a very hoarse voice. My doctor (neurologist) has stated that the disorder is purely physical and incurable. It can be treated with injections of botulinum toxin to the affected areas but the treatment is expensive, only moderately effective and must be repeated every 12 or 13 weeks. From what little I've managed to read about this disorder there appears to be some question as to whether its physical or psychological in origin. The disorder appears to be quite rare and I would very much like to find out if there is any research, physical treatments, psychological treatments or drug therapies that are directed towards this disorder. Thanks Larry larry@ljameson.bcsc.gov.bc.ca From owner-neuroscience@net.bio.net Thu Aug 04 23:00:00 1994 Path: biosci!rutgers!gatech!newsxfer.itd.umich.edu!uunet!hearst.acc.Virginia.EDU!gems.vcu.edu!jwwilliams From: jwwilliams@gems.vcu.edu Newsgroups: bionet.neuroscience Subject: Re: cerebellum Message-ID: <1994Aug5.163200.1733@gems.vcu.edu> Date: 5 Aug 94 16:32:00 -0400 References: <31ge5q$1nn@search01.news.aol.com> Organization: Medical College of Virginia Lines: 17 In article <31ge5q$1nn@search01.news.aol.com>, footc@aol.com (Foot C) writes: > Doaes anyone have an illustration of the homunculus in the cerebellum? Or > how to locate one. Thanks in Advance- > Kevin Kunz There is a homunculus using to cat in the cerebellum chapter of: Functional Neuroanatomy by N.B. Everett, Lea & Febiger, Philadelphia, 6th ed. 1971. Its not the greatest but it's the only one I've seen. I would be glad to fax a copy to you for prescreening before you take the time to find this text. E-mail me your fax number at jwwilliams@ruby.vcu.edu Jim Williams From owner-neuroscience@net.bio.net Thu Aug 04 23:00:00 1994 Path: biosci!VTBIT.CC.VT.EDU!RLINDEN%BRLNCC.BITNET From: RLINDEN%BRLNCC.BITNET@VTBIT.CC.VT.EDU (Rafael Linden) Newsgroups: bionet.neuroscience Subject: transfection Date: 5 Aug 1994 15:26:22 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 9 Sender: daemon@net.bio.net Distribution: world Message-ID: <199408052226.PAA13384@net.bio.net> NNTP-Posting-Host: net.bio.net Has anyone on the net had any experience in transfection of primary cultures of central neurons? I'd appreciate any hints. Rafael _____________ Rafael Linden IBCCF-UFRJ E-mail: RLINDEN@BRLNCC.BITNET Phone: 55-21-290-6897 Fax: 55-21-280-8193 From owner-neuroscience@net.bio.net Thu Aug 04 23:00:00 1994 Path: biosci!SALK.EDU!alain From: alain@SALK.EDU (Alain Destexhe) Newsgroups: bionet.neuroscience Subject: tutorial of thalamic oscillations on the NEURON simulator Date: 5 Aug 1994 10:49:25 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 86 Sender: daemon@net.bio.net Distribution: world Message-ID: <9408051749.AA08294@salk.edu> NNTP-Posting-Host: net.bio.net Demo Package for Simulations of Thalamic Networks with NEURON ------------------------------------------------------------- Alain Destexhe and Terrence Sejnowski The Howard Hughes Medical Institute and The Salk Institute, Computational Neurobiology Laboratory, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA electronic address: alain@salk.edu This package should be useful for anybody interested in the cellular mechanisms of synchronized oscillations in networks of inhibitory neurons, such as the thalamic reticular nucleus. It should be useful also for anybody interested in starting simulations of networks using the NEURON simulator. The thalamic reticular nucleus can be considered as essentially made of a homogeneous population of inhibitory neurons; its role in the genesis of sleep oscillations, its electrophysiological properties and the underlying ionic and synaptic currents have been extensively characterized by voltage-clamp and current-clamp experiments; its anatomical structure is also relatively simple. Taken together, these properties makes the thalamic reticular nucleus a nice system for building realistic models. Here we make available a package comprising 1. a postscript copy of a paper in press in J. Neurophysiology 2. NEURON files that generated the figures of this paper 3. movie files (mpeg) showing the propagating wave activity of the network All biological details about the ionic currents, synaptic interactions, and the topology of connections in the network, are described in detail in the paper (Destexhe et al., 1994). The package is available by anonymous ftp to salk.edu, in the directory /pub/alain The files contained in the package are: 1. isolRE.ps.Z: postscript copy of the J. Neurophysiol. paper in which the simulations are described (Destexhe et al., 1994). This article is useful as a guide to understand the simulations because all equations, geometries, parameters, etc, are explained in detail. This article also focuses on the biological motivations of the model. 2. demo_network.tar contains all the files needed to run the simulations using the Interviews version of NEURON. These files are commented and should run straighforwardly, provided the NEURON simulator is installed properly (see instructions in README_NETWORKS). 3. re100.mpg, re400.mpg, re400_spiral.mpg, re1600.mpg: set of movies, or animations, which illustrates the propagation of waves of activity in the network. These movies are a good complement to the snapshots of activity illustrated in the paper. There are also other files available (see the README document). WARNING: The simulations presented here have been tested on different machnines and in principle should run straightforwardly provided the Interviews version of NEURON is installed properly. The NEURON simulator is publically available on internet via anonymous ftp from neuron.neuro.duke.edu:/neuron. For more informations about how to get NEURON and how to install it, please refer to Michael Hines directly (hines@ctan.yale.edu). Reference Destexhe, A., Contreras, D., Sejnowski, T.J. and Steriade, M. A model of spindle rhythmicity in the isolated thalamic reticular nucleus. Journal of Neurophysiology 72: 803-818, 1994. From owner-neuroscience@net.bio.net Thu Aug 04 23:00:00 1994 Newsgroups: bionet.neuroscience Path: biosci!rutgers!gatech!howland.reston.ans.net!europa.eng.gtefsd.com!darwin.sura.net!nih-csl!postman From: tate@faxcsl.dcrt.nih.gov (Ramon Tate) Subject: Wanted: GUI compartmental modelling software source for Mac Message-ID: <1994Aug5.172016.28308@alw.nih.gov> Keywords: Mac, compartment, kinetic analysis Sender: postman@alw.nih.gov (AMDS Postmaster) Reply-To: tate@faxcsl.dcrt.nih.gov Organization: Computer Systems Lab., NIH Date: Fri, 5 Aug 1994 17:20:16 GMT Lines: 7 Although this may not be the right group for this question, it's as close as I can get, it seems. I am looking (for someone else) for a commercial [or public domain, for that matter] software package for the Macintosh that will permit the graphical modelling and solution of compartmental models (e.g. cellular, enzyme kinetics, etc.). Such a product has been seen at FASEB April '94, but the reference has been lost. Any help you can give is greatly appreciated. From owner-neuroscience@net.bio.net Thu Aug 04 23:00:00 1994 Path: biosci!rocbi.DNET.roche.com!schierh From: schierh@rocbi.DNET.roche.com Newsgroups: bionet.neuroscience Subject: The "nematode" H.sapiens Date: 5 Aug 1994 11:08:16 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 19 Sender: daemon@net.bio.net Distribution: world Message-ID: <9408051800.AA01791@mailgate.roche.com> NNTP-Posting-Host: net.bio.net Hi. Does anyone knows of any papers about the clonaje or caracterization of any C.elegans homologue gene expressed specificaly in the human brain during the organogenesis. I am not searching for transcription factors. Thank you very much!!! Hernu.- Hernan L. Schier. Facultad de Ciencias Exactas y Naturales Universidad de Buenos Aires; ARGENTINE. schierh@rocbi.dnet.roche.com public@fito.uba.ar From owner-neuroscience@net.bio.net Thu Aug 04 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!EU.net!Germany.EU.net!news.dfn.de!scsing.switch.ch!aragorn.unibe.ch!optolab!larkum From: larkum@optolab.unibe.ch (Matthew Larkum) Newsgroups: bionet.neuroscience Subject: Re: VOLTAGE-SENSITIVE DYES Date: 5 Aug 1994 12:57:55 GMT Organization: Physiological Institute, University of Berne, Switzerland Lines: 35 Distribution: world Message-ID: <31td0j$gpn@aragorn.unibe.ch> References: Reply-To: larkum@optolab.unibe.ch NNTP-Posting-Host: optolab.unibe.ch In article 0100000@ipruniv.cce.unipr.it, vetfisio@IPRUNIV.CCE.UNIPR.IT () writes: >Could anyone help me in choosing the appropriate voltage sensitive probe >for my experiments? I have to test the electrical activity of cultured >mammalian olfactory neurons in response to different odorants. I have a >fluorescent optic microscope with a connected camera, so I wonder if a >fluorescent probe could be a good idea. > >Pino Silvestri > >Vetfisio@ipruniv.cce.unipr.it You might want to get a copy of: Cinelli, A., Kauer, J.S., "Voltage-sensitive dyes and functional activity in the olfactory pathway", Annual Reviews in Neuroscience, 1992, 15:321-51. This reviews a lot of work on salamander olfactory system. Kauer also wrote a good article in Trends in Neuroscience in the last 2 years. Don't have the reference to hand. LaMantia, A.-S., Pomeroy, S.L., Purves, D., "Vital Imaging of Glomeruli in the Mouse Olfactory Bulb", Journal of Neuroscience, March 1992, 12(3): 976-988. They used RH414 and a Bio-Rad MRC500 laser-scanning confocal microscope but also give a list of other dyes they tried (26 of them!). Other dyes not mentioned in these are di-4-ANEPPS and di-8-ANEPPS that I know work well in rat spinal cord. By the way, if you're interested in recording activity in the form of action potentials, you're going to want better than the 25/50 Hz resolution that most European cameras have. Perhaps you have a wizz-bang camera, though. Other options seem to be limited to using a confocal microscope in line scan mode or an array of photodiodes. Matthew. larkum@optolab.unibe.ch From owner-neuroscience@net.bio.net Thu Aug 04 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!europa.eng.gtefsd.com!news.umbc.edu!haven.umd.edu!cs.umd.edu!eff!news.duke.edu!concert!hearst.acc.Virginia.EDU!portal.gmu.edu!mason1.gmu.edu!herwin From: herwin@mason1.gmu.edu (HARRY R. ERWIN) Newsgroups: bionet.neuroscience Subject: Inhibition and Maturation Date: 5 Aug 1994 12:54:00 GMT Organization: George Mason University, Fairfax, Virginia, USA Lines: 32 Message-ID: <31tcp8$sl1@portal.gmu.edu> NNTP-Posting-Host: mason1.gmu.edu Mime-Version: 1.0 Content-Type: text/plain; charset=US-ASCII Content-Transfer-Encoding: 7bit X-Newsreader: TIN [version 1.2 PL2] A few data points: 1. GABAergic synapses can be excitatory or inhibitory depending on the chloride gradient. Different channels are involved. 2. Buspirone and other anti-depressant/anti-anxiety drugs bind to inhibitory GABAergic receptors and facilitate chloride currents. 3. Anxiety often becomes milder during adolescence as the nervous system (particularly the GABAergic component) matures. 4. Post-natal changes in the chloride gradient do occur, with corresponding shifts of the GABAergic synapses from excitatory to inhibitory. Such a shift for a significant percentage of GABAergic synapses in the cortex would have a strongly non-linear effect on the dynamics (and functioning) of pyramidal cells based on some preliminary modeling I've been doing. In particular, activation networks would become more efficient at identifying and classifying non-novel patterns, which would reduce the perceived novelty of the world and the level of arousal of the person. This summer, I've watched an individual go from severe generalized anxiety to almost the opposite type of personality in two months. I didn't think the nervous system could change as fast as what I've observed. It almost looks like there has been a significant shift of GABAergic synapses from excitatory to inhibitory, which is one of those things that can be leveraged by a change in the chloride gradient. Does anyone have a clue? -- Harry Erwin Internet: herwin@gmu.edu Just a dumb engineer working on Katchalsky nets.... From owner-neuroscience@net.bio.net Thu Aug 04 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!EU.net!Germany.EU.net!news.dfn.de!urmel.informatik.rwth-aachen.de!news.rhrz.uni-bonn.de!matthias From: matthias@jersey.meb.uni-bonn.de (Matthias Duempelmann) Newsgroups: bionet.neuroscience Subject: Rotor sclicer system Date: 5 Aug 1994 09:37:25 GMT Organization: Bonn University - Clinic of Epileptology Lines: 12 Distribution: world Message-ID: <31t18l$kvq@news.rhrz.uni-bonn.de> NNTP-Posting-Host: jersey_tr.meb.uni-bonn.de Keywords: We are planning to buy a Rotorslicer system manufactured for npi electronics for our neurophysiology lab. Is anyone already working with this device or has further information on this system? Thanks Heinz E-mail: klaus@jersey.meb.uni-bonn.de From owner-neuroscience@net.bio.net Thu Aug 04 23:00:00 1994 Newsgroups: bionet.neuroscience Path: biosci!agate!doc.ic.ac.uk!daresbury!trane.uninett.no!eunet.no!nuug!EU.net!uunet!news.iij.ad.jp!wnoc-tyo-news!news.u-tokyo.ac.jp!news.tisn.ad.jp!aist.go.jp!ripspost!b0017 From: b0017@nibh.go.jp (Maurizio MORABITO; Tel.6661) Subject: Re: Tourette Syndrome In-Reply-To: mana@bns.pitt.edu's message of Thu, 4 Aug 1994 20:37:38 Message-ID: Sender: news@aist.go.jp Nntp-Posting-Host: 150.29.56.34 Organization: National Institue of Bioscience and Human-Technology(NIBH), Japan. References: Date: Fri, 5 Aug 1994 04:26:30 GMT Lines: 5 thank you very much maurizio -- Maurizio Morabito maurizio@nibh.go.jp From owner-neuroscience@net.bio.net Thu Aug 04 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!gatech!newsxfer.itd.umich.edu!newsrelay.iastate.edu!hobbes.physics.uiowa.edu!newsfeed.ksu.ksu.edu!moe.ksu.ksu.edu!vixen.cso.uiuc.edu!mac5.life.uiuc.edu!user From: jbuberel@uiuc.edu (Jason L. Buberel) Newsgroups: bionet.neuroscience Subject: Skatchard Analysis on the mac? Date: Fri, 05 Aug 1994 18:05:37 -0500 Organization: University of Illinois, Neuroscience Department Lines: 18 Message-ID: NNTP-Posting-Host: mac5.life.uiuc.edu Neuroscientists, Would anyone out there like to reccomend a mac (preferably PowerMac) software that will do a Skatchard analysis? If it will support multiple binding sites/receptor subtypes, that would be great. Reply via e-mail or post, thanks, jason -- Jason L. Buberel Graduate Student Neuroscience Program University of Illinois jbuberel@uiuc.edu 217.244.0115 From owner-neuroscience@net.bio.net Thu Aug 04 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!news.cac.psu.edu!news.pop.psu.edu!ra.nrl.navy.mil!usenet From: mcfarlan@seas.gwu.edu (Daniel McFarlane) Newsgroups: bionet.neuroscience Subject: NervousSystem: Neuron Modeling & Simulation Tool Date: 5 Aug 1994 22:33:41 GMT Organization: George Washington University Lines: 103 Sender: mcfarlan@itd.nrl.navy.mil Message-ID: <31ueo5$5kd@ra.nrl.navy.mil> NNTP-Posting-Host: xoxo.itd.nrl.navy.mil X-Posted-From: InterNews 1.0.1@xoxo.itd.nrl.navy.mil X-Authenticated: mcfarlan on Unix host itd.nrl.navy.mil We announce the release for free distribution of "NervousSystem 1.0.gwu"; a neuron modeling and simulation environment for Apple Macintosh computers (application, source code, and documentation). "NervousSystem" is a useful context for learning/teaching two popular topics: computational neuroscience, and object-oriented programming within a framework. Here are the contents of the "Read Me" file. *** ANNOUNCING: *** NervousSystem 1.0.gwu -- Neuron Modeling and Simulation Environment for Apple Macintosh *** WHAT: *** NervousSystem is an exciting new simulation tool for exploring the behavior of networks of neurons, based on a biological model. 1. Application (Apple Macintosh computers); 2. User's Guide (MS Word format); 3. Source Code & Project File (OOP using the Think Class Library Framework); 4. Programmer's Guide (MS Word format). *** WHY (For Computational Neuroscience): *** NervousSystem has the following attractive properties for investigating a biologically based model of neurons and networks of neurons. 1. free; 2. it is VERY easy to learn and use (direct manipulation interaction style); 3. "easily" expandable and customizable because of well structured OOP source code; 4. free. *** WHY (For Computer Science): *** NervousSystem has the following attractive properties for learning direct-manipulation object-oriented programming within a framework. 1. free; 2. elegant direct-manipulation solution; 3. employs "Model-View-Controller" paradigm; 4. popular OOP language, C++ (Think Class Objects); 5. popular framework (Think Class Library); 6. popular, and inexpensive, development tools (Think C v.5, and AppMaker); 7. well crafted by OOP experts (two doctoral student in human-computer interaction at George Washington University); 8. robust, ample structure, supports expansion and reuse; 9. free. *** WHERE: *** This software is now available by anonymous ftp from Info-Mac, "sumex-aim.stanford.edu", in the directory, "sci". The file is named "nervous-system-10.hqx". I suggest copying NervousSystem from a mirror site, sumex is often too busy (for example, "grind.isca.uiowa.edu" "mac/infomac/sci/nervous-system-10.hqx"). *** WHEN: *** Now!! (as of July 1994) *** HOW: *** It's free (and for non-profit use) -- Copy it by anonymous ftp! "NervousSystem.sea" is a self-extracting compressed file. After copying it to your local directory, double click on it. "NervousSystem.1.0.gwu.sea" will self-extract into a folder named "NervousSystem". The application, source, user's guide, programmer's guide, and "Read Me" are located within this folder. *** WHO: *** Daniel C. McFarlane The Naval Research Laboratory, Code 5513 Human-Computer Interaction Lab 4555 Overlook Ave., N.W. Washington, D.C. 20375-5337 mcfarlan@seas.gwu.edu (internet address) Joe Geigel Pittsburgh Supercomputing Center BioMedical Group *** DETAILS: *** We release these NervousSystem products under the terms of the GNU General Public License Version 2 as published by the Free Software Foundation, Inc., 675 Massachusetts Ave., Cambridge, MA 02139, 617-876-3296. (A copy of this license is included in the Programmer's Guide.) Please feel free to redistribute it as you see fit (according to the provisions of the GNU General Public License). Copyright (c) 1994, Daniel C. McFarlane and Joe Geigel. We hope that you will find this program useful. However, there is NO WARRANTY WHATEVER. We do not offer any warranty or guarantee of any kind, implied or otherwise. The uncompressed "NervousSystem" folder will require about 5MB of hard disk space. I am curious about the future of NervousSystem. If you copy it, and are interested in it, please send me a note at mcfarlan@seas.gwu.edu and just let me know who you are. From owner-neuroscience@net.bio.net Thu Aug 04 23:00:00 1994 Path: biosci!bcm!NewsWatcher!user From: nmoreno@bcm.tmc.edu (Nancy Moreno) Newsgroups: bionet.neuroscience Subject: BrainLink: Neuroscience activities for kids Followup-To: bionet.neuroscience Date: 5 Aug 1994 14:44:14 GMT Organization: Baylor College of Medicine Lines: 50 Distribution: world Message-ID: NNTP-Posting-Host: 128.249.102.75 Are you working with students in schools or interested in helping children discover the excitement of "doing" science? BrainLink offers unique materials and activities in neuroscience to carry out in the classroom with students in grades K-8. Funded by the National Institutes of Health, BrainLink has been developed collaboratively by researchers, clinicians and educators at Baylor College of Medicine and is designed to teach elementary and early middle school students about the brain and nervous system, while fostering awareness of science and health careers, promoting healthy behaviors and allowing teachers and students to explore science concepts through hands-on, discovery-oriented approaches. Each BrainLink unit focuses on a central neuroscience topic that is maintained throughout the three interrelated components described below. - - - - - - - Adventures in Neuroscience is a series of stories about a group of children who call themselves the NeuroExplorers. Neuroscience concepts are introduced within the plot of each story. In the first story, "Skullduggery," for example, the NeuroExplorers learn about the physical brain and the skull while they unravel the mystery behind a stolen archaelogical artifact. Explorations in Neuroscience is a mini-magazine filled with information and fun activities that encourage children and parents to carry out neuroscience activities together. Activities in Neuroscience is a teacher guide that provides activity-based lessons for classroom use, along with necessary background information for teachers. The activities entice students to discover neuroscience concepts through hands-on exploration. For example, in the first unit, "Brain Comparisons," students learn about the weight and fragile nature of the brain, using a three pound water ballon as a model. - - - - - - - Four BrainLink units are available: Brain Comparisons, Motor Highways, Sensory Systems and Memory and Learning. The units have been field tested in Houston-area schools during the past two years. Students reported "liking" and "learning something" from the materials, while teachers rated BrainLink highly for its educational value. For more information about BrainLink, please contact: Nancy Moreno, Ph.D.,Judith Dresden, Barbara Tharp, or Leslie Miller, Ph.D., Division of School-Based Programs, Baylor College of Medicine, 1709 Dryden, Suite 545, Houston, Texas 77030; phone (713) 798-8200; fax (713) 798-8201; email nmoreno@bcm.tmc.edu. From owner-neuroscience@net.bio.net Fri Aug 05 23:00:00 1994 Path: biosci!agate!library.ucla.edu!europa.eng.gtefsd.com!newsxfer.itd.umich.edu!uunet!munnari.oz.au!yoyo.aarnet.edu.au!news.adelaide.edu.au!gateway.dircsa.org.au!cleese.apana.org.au!gastro!terrys From: terrys@gastro.apana.org.au (Terry Smith) Date: 06 Aug 94 15:56:36 -1030 Newsgroups: bionet.neuroscience Subject: melatonin Message-ID: <169_9408061850@gastro.apana.org.au> X-Mail-Agent: GIGO+ sn 133 at gastro vsn 0.99 pl1 X-FTN-To: vgupta@guvax.acc.georgetown.edu Organization: Fidonet: Point Taken. Lines: 23 vage> From: vgupta@guvax.acc.georgetown.edu vage> Date: 1 Aug 94 13:54:42 -0500 vage> Is there any research on Melatonins affect on mood? I suffer vage> from SAD [seasonal affective disorder] and would like to vage> know whether neuroscince has pinned down any definative vage> explanation of winter depression. May I suggest getting in touch with Dr Drew Dawson at Adelaide University, or Dr Leon Lack at Flinder's [both in South Australia]. Both have done work in this field, and both Leon's and Drew's work in entraining methods have been fruitful in treating SAD. I'm sorry I don't have an internet address for either, but they would be a good place to start in any citation /abstract search. Terry Smith ------------------------------------------------------ [This seems a good a place as any for putting useless silly information that people can read to make up for wasting time on the body of the message] ------------------------------------------------------ From owner-neuroscience@net.bio.net Fri Aug 05 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!europa.eng.gtefsd.com!news.umbc.edu!haven.umd.edu!umd5.umd.edu!not-for-mail From: pcanova@hamlet.umd.edu (Pam Canova) Newsgroups: bionet.neuroscience Subject: Need info. on med. problem Date: 6 Aug 1994 09:44:28 -0400 Organization: University of Maryland, College Park Lines: 18 Message-ID: <32043s$vo@hamlet.umd.edu> NNTP-Posting-Host: hamlet.umd.edu Hi, I had a question regarding neurological and possibly psychobiological problems I have been having. I have been suffering from some depersonalization type problems, like extremely poor memory, slow reaction time, not feeling awake or aware, and being very nervous in general. In fact, recently, when someone calls my name from behind I either jump, or I feel a "pulse" of my nerves down my arms and across my face. It happens any time I am surprised or am trying to phsycally do something quickly. I feel extremely tired all the time, though I get plenty of sleep, and have been tried on a number of different medications. Someone recommended that I be tried on tricyclics for at least three months, can anyone say what they are supposed to do? Any and all help appreciated, Pam -- @@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ "If life's a cabaret, then I'm sitting behind a woman with really big hair." from Rita Rudner's smashing book "Naked Beneath My Clothes" Shocking! Pam Canova pcanova@umd5.umd.edu From owner-neuroscience@net.bio.net Sat Aug 06 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!swrinde!pipex!sunic!trane.uninett.no!eunet.no!nuug!EU.net!uunet!zib-berlin.de!rs1-hrz.uni-duisburg.de!news.rz.uni-duesseldorf.de!usenet From: "Andreas Bohlen" Newsgroups: bionet.virology,bionet.neuroscience,bionet.molbiol.hiv Subject: BIOTEC 94 - Forum of Biotechnology in Duesseldorf Nov 16-19,1994 Date: Sun, 7 Aug 94 15:12:33 +0100 Organization: Heinrich Heine Universitaet Duesseldorf Lines: 175 Message-ID: <66512.bohlen@mail.rz.uni-duesseldorf.de> Reply-To: NNTP-Posting-Host: 134.99.128.136 X-Minuet-Version: Minuet1.0_Beta_14 X-POPMail-Charset: English Xref: biosci bionet.virology:741 bionet.neuroscience:3993 BIOTEC 94 Forum of Biotechnology/Biomedicine for Science, Technology and Medicine Duesseldorf, Germany - November 16-19, 1994 **************************************************************** In co-operation with the Institute of Microbiology of the Heinrich-Heine-Universitaet Duesseldorf (Germany) and the Messe Duesseldorf we organize the BIOTEC 94 Forum of Biotechnology, which takes place parallel with the MEDICA Fair, one of the world's largest fairs in the field of medicine. The International Forum of Biotechnology BIOTEC 94 offers you an ideal platform for presenting your state-of-the-art innovations in the field of research and development in industry and higher education. In addition to the scientific BIOTEC Congress we give you the opportunity to present your products, services and developments within the framework of the BIOTEC Special Exhibition. Thanks to its links with the MEDICA and an expected number of about 100,000 visitors, the BIOTEC Special Exhibition promises to generate widespread interest. Additionally you can take part in the Technology Forum, which opens the way to communication with scientists, practitioners, politicians and the industry. ***** PRELIMINARY PROGRAMME ***** BIOTEC 94 International Forum of Biotechnology/Biomedicine for Science, Technology and Medicine THE INTERNATIONAL CONGRESS PRESENTS: Summary lectures by internationally recognized scientists on selected topics in research and development, plus poster sessions to the same topics (Closing date for poster abstracts: October 15, 1994) THE TECHNOLOGY FORUM PRESENTS: A podium for the discussion of the development of biotechnology/biomedicine in Europe and Germany and problems and opportunities of technology transfer to small and large companies. THE INTERNATIONAL BIOTEC/MEDICA SPECIAL EXHIBITION Scheduled parallel with the MEDICA 94 the INTERNATIONAL BIOTEC/MEDICA SPECIAL EXHIBITION offers the chance of show-casing biotechnology and biomedicine products, techniques and equipment. In addition, scientists and companies will have the opportunity to present their projects and products in form of EXHIBITOR SEMINARS. SHORT COURSES on techniques for scientists, clinicians and technicians on the following topics: - new PCR applications; Dr. M. Kroeger, Giessen - new assays in molecular diagnostics; Dr. M. Bielefeld, Duesseldorf - progress in gene diagnosis; Dr. A. Reis, Berlin - clinical prospects of gene therapy; Dr. P. Wehling, Duesseldorf - measuring neurochemical activity in normal and pathological brain function; Dr. R. K. W. Schwarting, Duesseldorf +++ WEDNESDAY, NOVEMBER 16, 1994 +++ CONGRESS Main topic of lectures and poster session: GENE TECHNOLOGY FOR FOOD PRODUCTION Session organizer: Prof. Dr. K.-D. Jany, Karlsruhe Joint meeting with the German Society of Nutrition TECHNOLOGY FORUM Biotechnology/Biomedicine - Fortress Europe? - Position of biotecnology/biomedicine in the USA, Japan, South America and Asia in comparison with Europe +++ THURSDAY, NOVEMBER 17, 1994 +++ CONGRESS Main topic of lectures and poster session: NEW DIAGNOSTIC METHODS IN RESEARCH AND APPLICATIONS Session organizer: Prof. Dr. F. J. Fehrenbach, Berlin Prof. Dr. U. Hadding, Duesseldorf Joint meeting with the German Society of Hygiene and Microbiology, Division of Diagnostic Methods TECHNOLOGY FORUM Location Germany for Research and Development - Perspectives in biotechnology/biomedicine from the view of science and industry including job market for biotechnology +++ FRIDAY, NOVEMBER 18, 1994 +++ CONGRESS Main topic of lectures and poster session: SOMATIC GENE THERAPY Session organizer: Prof. Dr. M. F. Rajewski, Essen Prof. Dr. R. Mertelsmann, Freiburg Joint meeting with the German Cancer Society, Section of Experimental Cancer Research TECHNOLOGY FORUM Technology transfer in biotechnology/biomedicine - Cooperation between universities and research institutes and small and large industrial enterprises - Models to promote a more efficient information and technology exchange +++ SATURDAY, NOVEMBER 19, 1994 +++ CONGRESS Main topic of lectures and poster session: NEUROBIOTECHNOLOGY: NEURONAL DISFUNCTION AND REPAIR Session organizer: Prof. Dr. J. P. Huston, Duesseldorf Joint meeting with the European Brain Behaviour Society (EBBS) TECHNOLOGY FORUM / PANEL DISCUSSION ACCEPTANCE OF GENE TECHNOLOGY IN FOOD PRODUCTION (in German language only) * * * If you are interested in the BIOTEC 94, please don't hesitate to send us the filled-in "info-coupon" below via email. We will send you the information folder, the application forms and the conference material of the BIOTEC 92 Forum. Thank you very much for your interest. Andreas Bohlen Department of Research and Technology Transfer University of Duesseldorf **************************************************************************** * INFO-COUPON * **************************************************************************** I would like more details on BIOTEC 94: [ ] Congress programme [ ] I would like to present a poster on the following congress topic: ................................................................. [ ] As a scientist / company I would like to present at the Special Exhibition the following project: ................................................................. Closing date for posters and projects: October 15, 1994 Applications only in connection with abstracts (1 page). [ ] I would like to attend the following short course: ................................................................. [ ] As a company I would like to exhibit in the Special Exhibition of BIOTEC 94. Please send exhibitor information. Name: .................................... College/Company/Institute: .................................... Street/PO Box: .................................... Town/Postcode: .................................... Phone No. .................................... Fax No. .................................... Email address: .................................... ************************************************************** * Heinrich-Heine-Universitaet Duesseldorf * * Forschungs- und Technologie-Transfer * * Dr. Volker Hempel * * Magdalena Schoenfeld * * Universitaetsstr. 1, Gebaeude 16.11, D-40225 Duesseldorf * * Tel. (0211) 3 11-52 35/-32 65 Fax (0211) 34 22 29 * * E-Mail hempel@uni-duesseldorf.de * ************************************************************** Any mail to Dr. Bohlen of the University of Potsdam, Dept. of Information and Technology Transfer should be sent to: bohlen@hp.rz.uni-potsdam.de He finished working in Duesseldorf on July 31, 1994 and will be only available in Potsdam from now on. From owner-neuroscience@net.bio.net Sat Aug 06 23:00:00 1994 Newsgroups: bionet.neuroscience Path: biosci!agate!howland.reston.ans.net!newsserver.jvnc.net!yale.edu!noc.near.net!news.tufts.edu!opal.tufts.edu!sstrain_ssb From: sstrain_ssb@opal.tufts.edu Subject: PC-12 sub-clone wanted Message-ID: <1994Aug6.212418.1@opal.tufts.edu> Lines: 5 Sender: news@news.tufts.edu (USENET News System) Organization: Tufts University - Medford, MA Date: Sun, 7 Aug 1994 02:24:18 GMT I'm trying to look at receptor-mediated Ca++ flux in cell culture. Does anyone have a sub-clone of PC-12 available which has a high responsiveness to muscarinic agonists? Most of the references I have found have been from Italy and I would like to find a source in the US. Please EMAIL your reply if possible. Thanks!! From owner-neuroscience@net.bio.net Sat Aug 06 23:00:00 1994 Path: biosci!agate!spool.mu.edu!nigel.msen.com!zib-berlin.de!rs1-hrz.uni-duisburg.de!news.rz.uni-duesseldorf.de!usenet From: "Andreas Bohlen" Newsgroups: bionet.virology,bionet.neuroscience,bionet.molbiol.hiv Subject: Symposium FRONTIERS IN BIOSENSORICS in Potsdam, Germany Date: Sun, 7 Aug 94 15:30:45 +0100 Organization: Heinrich Heine Universitaet Duesseldorf Lines: 208 Message-ID: <67505.bohlen@mail.rz.uni-duesseldorf.de> Reply-To: NNTP-Posting-Host: 134.99.128.136 X-Minuet-Version: Minuet1.0_Beta_14 X-POPMail-Charset: English Xref: biosci bionet.virology:743 bionet.neuroscience:3995 Ladies and Gentlemen, the symposium "Frontiers in Biosensorics" will take place at the University in Potsdam on December 15-16. Enclosed you will find the preliminary programme of the symposium. All lectures will be given in German. Thursday, December 15, 1994 ********************************************************************** 10.00 am Opening Prof. Dr. Rolf Mitzner Rector of the University of Potsdam Dr. Jutta Fedrowitz Science Center North Rhine-Westfalia, Duesseldorf 10.30 am Introduction Prof. Dr. Frieder W. Scheller Inst. of Biochemistry and Molecular Physiology, Univ. of Potsdam 11.00 am Coffee Break NEW BIOMOLECULES 11.30 am Screening and characterization of new enzymes for analytics PD Dr. Werner Hummel Univ. od Duesseldorf / KFA Juelich 12.00 am Enzyme mechanisms Prof. Dr. Martin Peter Inst. of Organic Chemistry, Univ. of Potsdam 01.00 pm Lunch Break 02.00 pm Imprinting techniques in synthetic polymers - new prospects for chemosensors Prof. Dr. Guenter Wulff Inst. of Organic Chemistry and Macromolecular Chemistry Univ. of Duesseldorf 02.30 pm Single molecule analytics by fluorescence correlation spectroscopy Dr. Carsten Henco Erotec Biosystems, Hamburg THIN LAYERS 03.00 pm Thin organic layers Prof. Dr. Ludwig Brehmer Inst. of Physics of Condensed Matter, Univ. of Potsdam 03.30 pm Foerster energy transfer and ultra-thin polymer layers as a basis for biosensors Dr. Michael Voelker BAYER AG, Uerdingen 04.00 pm Coffee break 04.30 pm Electropolymers for biosensors, electrochemical microtechnologies Prof. Dr. Joachim Walter Schultze Inst. of Physical Chemistry and Electrical Chemistry Univ. of Duesseldorf 05.00 pm Polymer layer systems Prof. Dr. Moehwald Inst. of Physics of Condensed Matter, Univ. of Potsdam 05.30 pm Microbiosensors Dr. Rainer Hintsche Fraunhofer Institute of Microsystem Technology, Berlin 06.00 pm End of lectures 07.00 pm Reception of the participants + Informal Get Together Friday, December 16, 1994 ********************************************************************* BIOSENSOR APPLICATIONS 09.00 am Connective protein - anti-body - identification systems Prof. Dr. Friedrich Spener Institute of Chemo- and Biosensorics, Muenster 09.30 am Biosensors with modified electrode surfaces for in and ex vivo applications Dr. Gerald Urban Inst. of General Electrotechnics and Electronics, Vienna 10.00 am Integration and miniaturization in the preparation of samples Dr. Andreas Menz Ciba, Basel 10.30 am Coffee break 11.00 am New biosensors for environmental analytics Prof. Dr. Hansen Technical University Berlin 11.30 am Commercial biosensors Dr. Dorothea Pfeiffer BSZ Bio Sensor Technologie, Berlin Additional programme ******************************************************* o Information and Technology Transfer Cooperation Fair Science-Industry Potsdamer Informations- und Technologie-Transfer (PITT) der Universitaet Potsdam o Exhibition "Commercial Biosensors" The participation fee is DM 110,- (students DM 55,-). It includes lunch on both days, coffee and sandwiches during the breaks, the official reception on the evening of the first day the symposium folder. The fee for the participation in the Special Exhibition "Commercial Biosensors" is DM 200,- for companies. It is free of charge for companies sponsoring the symposium. If you are interested in the symposium, please fill in the form below and resend it to us. Thank you very much in advance for your interest. Yours sincerely, Dr. Andreas Bohlen Please send the email reply to the following address: bohlen@hp.rz.uni-potsdam.de >>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>> EMAIL REPLY <<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<< [ ] I will take part in the symposium "Frontiers in Biosensorics" at the University of Potsdam. Please send me the official programme and the application form of the symposium. [ ] I/we will take part in the Special Exhibition "Commercial Biosensors", which will take place parallel with the symposium. [ ] We would like to present our company, whose main fields of research and development are: ............................................................ [ ] We would like to present a cooperation project under the headline: ............................................................ [ ] We would like to sponsor the symposium with a sum of ..... DM. Please send us some more information on the event. [ ] We are interested in the Cooperation Fair Science-Industry and are especially looking for cooperation partners in the follwing field(s): ..................................................................... ..................................................................... [ ] Regrettably we cannot take part in the symposium but we are interested in [ ] information on the symposium "Frontiers in Biosensorics" [ ] contacts with scientists at the University of Potsdam in the following fields of research: ................................................................ [ ] the Department of Information and Technology Transfer (PITT) at the University of Potsdam [ ] biosensorics at the Univ. of Potsdam [ ] the Univ. of Potsdam in general Academic title: ........................................ Name: ........................................ First name: ........................................ Company/Institution: ........................................ Dept./Branch ........................................ Address: ........................................ ........................................ ........................................ Postal code + town: ........................................ Country: ........................................ Phone number: ........................................ Fax number: ........................................ Email: ........................................ >>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>-- --- ************************************************************** * Heinrich-Heine-Universitaet Duesseldorf * * Forschungs- und Technologie-Transfer * * Dr. Volker Hempel * * Magdalena Schoenfeld * * Universitaetsstr. 1, Gebaeude 16.11, D-40225 Duesseldorf * * Tel. (0211) 3 11-52 35/-32 65 Fax (0211) 34 22 29 * * E-Mail hempel@uni-duesseldorf.de * ************************************************************** Any mail to Dr. Bohlen of the University of Potsdam, Dept. of Information and Technology Transfer should be sent to: bohlen@hp.rz.uni-potsdam.de He finished working in Duesseldorf on July 31, 1994 and will be only available in Potsdam from now on. From owner-neuroscience@net.bio.net Sat Aug 06 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!europa.eng.gtefsd.com!newsxfer.itd.umich.edu!zip.eecs.umich.edu!umn.edu!zib-berlin.de!rs1-hrz.uni-duisburg.de!news.rz.uni-duesseldorf.de!usenet From: "Andreas Bohlen" Newsgroups: bionet.virology,bionet.neuroscience,bionet.molbiol.hiv Subject: Symposium FRONTIERS IN BIOSENSORICS in Potsdam, Germany Date: Sun, 7 Aug 94 15:27:31 +0100 Organization: Heinrich Heine Universitaet Duesseldorf Lines: 206 Message-ID: <67329.bohlen@mail.rz.uni-duesseldorf.de> Reply-To: NNTP-Posting-Host: 134.99.128.136 X-Minuet-Version: Minuet1.0_Beta_14 X-POPMail-Charset: English Xref: biosci bionet.virology:742 bionet.neuroscience:3994 Ladies and Gentlemen, the symposium "Frontiers in Biosensorics" will take place at the University in Potsdam on December 15-16. Enclosed you will find the preliminary programme of the symposium. All lectures will be given in German. 1st Day ********************************************************************** 10.00 am Opening Prof. Dr. Rolf Mitzner Rector of the University of Potsdam Dr. Jutta Fedrowitz Science Center North Rhine-Westfalia, Duesseldorf 10.30 am Introduction Prof. Dr. Frieder W. Scheller Inst. of Biochemistry and Molecular Physiology, Univ. of Potsdam 11.00 am Coffee Break NEW BIOMOLECULES 11.30 am Screening and characterization of new enzymes for analytics PD Dr. Werner Hummel Univ. od Duesseldorf / KFA Juelich 12.00 am Enzyme mechanisms Prof. Dr. Martin Peter Inst. of Organic Chemistry, Univ. of Potsdam 01.00 pm Lunch Break 02.00 pm Imprinting techniques in synthetic polymers - new prospects for chemosensors Prof. Dr. Guenter Wulff Inst. of Organic Chemistry and Macromolecular Chemistry Univ. of Duesseldorf 02.30 pm Single molecule analytics by fluorescence correlation spectroscopy Dr. Carsten Henco Erotec Biosystems, Hamburg THIN LAYERS 03.00 pm Thin organic layers Prof. Dr. Ludwig Brehmer Inst. of Physics of Condensed Matter, Univ. of Potsdam 03.30 pm Foerster energy transfer and ultra-thin polymer layers as a basis for biosensors Dr. Michael Voelker BAYER AG, Uerdingen 04.00 pm Coffee break 04.30 pm Electropolymers for biosensors, electrochemical microtechnologies Prof. Dr. Joachim Walter Schultze Inst. of Physical Chemistry and Electrical Chemistry Univ. of Duesseldorf 05.00 pm Polymer layer systems Prof. Dr. Moehwald Inst. of Physics of Condensed Matter, Univ. of Potsdam 05.30 pm Microbiosensors Dr. Rainer Hintsche Fraunhofer Institute of Microsystem Technology, Berlin 06.00 pm End of lectures 07.00 pm Reception of the participants + Informal Get Together 2nd Day ********************************************************************* BIOSENSOR APPLICATIONS 09.00 am Connective protein - anti-body - identification systems Prof. Dr. Friedrich Spener Institute of Chemo- and Biosensorics, Muenster 09.30 am Biosensors with modified electrode surfaces for in and ex vivo applications Dr. Gerald Urban Inst. of General Electrotechnics and Electronics, Vienna 10.00 am Integration and miniaturization in the preparation of samples Dr. Andreas Menz Ciba, Basel 10.30 am Coffee break 11.00 am New biosensors for environmental analytics Prof. Dr. Hansen Technical University Berlin 11.30 am Commercial biosensors Dr. Dorothea Pfeiffer BSZ Bio Sensor Technologie, Berlin Additional programme ******************************************************* o Information and Technology Transfer Cooperation Fair Science-Industry Potsdamer Informations- und Technologie-Transfer (PITT) der Universitaet Potsdam o Exhibition "Commercial Biosensors" The participation fee is DM 110,- (students DM 55,-). It includes lunch on both days, coffee and sandwiches during the breaks, the official reception on the evening of the first day the symposium folder. The fee for the participation in the Special Exhibition "Commercial Biosensors" is DM 200,- for companies. It is free of charge for companies sponsoring the symposium. If you are interested in the symposium, please fill in the form below and resend it to us. Thank you very much in advance for your interest. Yours sincerely, Dr. Andreas Bohlen Please send the email reply to the following address: bohlen@hp.rz.uni-potsdam.de >>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>> EMAIL REPLY <<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<< [ ] I will take part in the symposium "Frontiers in Biosensorics" at the University of Potsdam. Please send me the official programme and the application form of the symposium. [ ] I/we will take part in the Special Exhibition "Commercial Biosensors", which will take place parallel with the symposium. [ ] We would like to present our company, whose main fields of research and development are: ............................................................ [ ] We would like to present a cooperation project under the headline: ............................................................ [ ] We would like to sponsor the symposium with a sum of ..... DM. Please send us some more information on the event. [ ] We are interested in the Cooperation Fair Science-Industry and are especially looking for cooperation partners in the follwing field(s): ..................................................................... ..................................................................... [ ] Regrettably we cannot take part in the symposium but we are interested in [ ] information on the symposium "Frontiers in Biosensorics" [ ] contacts with scientists at the University of Potsdam in the following fields of research: ................................................................ [ ] the Department of Information and Technology Transfer (PITT) at the University of Potsdam [ ] biosensorics at the Univ. of Potsdam [ ] the Univ. of Potsdam in general Academic title: ........................................ Name: ........................................ First name: ........................................ Company/Institution: ........................................ Dept./Branch ........................................ Address: ........................................ ........................................ ........................................ Postal code + town: ........................................ Country: ........................................ Phone number: ........................................ Fax number: ........................................ Email: ........................................ >>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>> ************************************************************** * Heinrich-Heine-Universitaet Duesseldorf * * Forschungs- und Technologie-Transfer * * Dr. Volker Hempel * * Magdalena Schoenfeld * * Universitaetsstr. 1, Gebaeude 16.11, D-40225 Duesseldorf * * Tel. (0211) 3 11-52 35/-32 65 Fax (0211) 34 22 29 * * E-Mail hempel@uni-duesseldorf.de * ************************************************************** Any mail to Dr. Bohlen of the University of Potsdam, Dept. of Information and Technology Transfer should be sent to: bohlen@hp.rz.uni-potsdam.de He finished working in Duesseldorf on July 31, 1994 and will be only available in Potsdam from now on. From owner-neuroscience@net.bio.net Sun Aug 07 23:00:00 1994 Path: biosci!daresbury!not-for-mail From: MJ Duggan Newsgroups: bionet.neuroscience Subject: Inhibition and Maturation (fwd) Date: 8 Aug 1994 13:32:33 +0100 Lines: 62 Sender: lpddist@mserv1.dl.ac.uk Distribution: bionet Message-ID: <3258l1$keq@mserv1.dl.ac.uk> Original-To: neur-sci@dl.ac.uk Harry Erwin wrote > > 1. GABAergic synapses can be excitatory or inhibitory depending on the > chloride gradient. Different channels are involved. NO. All GABA(A) receptors found so far have integral chloride channels although some have a slight rectifying curve on their I/V plots it is only slight. Thus, all GABA(A) recptors should be capable of being inhibitory or excitatory depending only on the chloride gradient. > > 2. Buspirone and other anti-depressant/anti-anxiety drugs bind to > inhibitory GABAergic receptors and facilitate chloride currents. Not true. Buspirone is a 5-HT (serotonin) agonist. All the classic antidepressants have monoaminergic activities (e.g reuptake inhibition) the classical anxiolytics (benzodiazepines such as Valium) do facilitate GABA(A) receptor chloride channels, but this is by no means the only available mechanism. > > 3. Anxiety often becomes milder during adolescence as the nervous system > (particularly the GABAergic component) matures. > > 4. Post-natal changes in the chloride gradient do occur, with > corresponding shifts of the GABAergic synapses from excitatory to > inhibitory. Such a shift for a significant percentage of GABAergic > synapses in the cortex would have a strongly non-linear effect on the > dynamics (and functioning) of pyramidal cells based on some preliminary > modeling I've been doing. In particular, activation networks would become > more efficient at identifying and classifying non-novel patterns, which > would reduce the perceived novelty of the world and the level of arousal > of the person. How far post-natal are we talking about here? e.g adult or immediately post- natal when normal developmental changes are occuring? > > This summer, I've watched an individual go from severe generalized anxiety > to almost the opposite type of personality in two months. I didn't think > the nervous system could change as fast as what I've observed. Hold on a minute. When you can get radical changes in gene expression in a few hours. And learned response changes (presumably involving synaptic reorganiastion over hours/days. Then 2 months is too short a time to get behavioural/personality changes? .................................................................. It almost > looks like there has been a significant shift of GABAergic synapses from > excitatory to inhibitory, which is one of those things that can be > leveraged by a change in the chloride gradient. Does anyone have a clue? > My suggestion is that it is an interesting idea that changes in chloride gradients could lead to behavioural changes in adults but that you need to look at it more critically. How would a change in chloride gradient come about? Decrease in extracellular [Cl]? Increase in intracellular [Cl] The second sounds most likely, but what would this do to the membrane potential as a whole? Not just at GABAergic synapses? Thewhole thing sounds as though you have fallen in love with your own theory just a bit to fast. regards Mike Duggan From owner-neuroscience@net.bio.net Sun Aug 07 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!news.cac.psu.edu!news.tc.cornell.edu!travelers.mail.cornell.edu!newsstand.cit.cornell.edu!news.graphics.cornell.edu!ghost.dsi.unimi.it!univ-lyon1.fr!swidir.switch.ch!cisun2000.unil.ch!pcanat408b.unil.ch!roger From: roger@anatsg1.unil.ch (Roger DuBois) Newsgroups: bionet.neuroscience Subject: Re: Dolphin sleep Date: Mon, 8 Aug 1994 12:02:13 Organization: Institut d'Anatomie Lines: 39 Message-ID: References: <31ciov$1oa@franklin.cc.utas.edu.au> NNTP-Posting-Host: pcanat408b.unil.ch X-Newsreader: Trumpet for Windows [Version 1.0 Rev A] In article asa3h@galen.med.Virginia.EDU (Adam Stephen Arthur) writes: >From: asa3h@galen.med.Virginia.EDU (Adam Stephen Arthur) >Subject: Re: Dolphin sleep >Date: Wed, 3 Aug 1994 13:57:31 GMT >I think its fabulous that one idiotic post here has turned into >some truly intriguing info/speculation. While I am not >completely certain of all the implications of "unihemisphereic >sleep" I find it fascinating. Idiotic? It was meant to be provocative (and light hearted). We are at least now talking about dolphins instead of trying to talk to them. I am very concerned about mechanisms of sensory encoding and in particular, how completelydifferent sensory modalities are processed by neural cortex which is essentially homogenous. Consider, for example, how different are the processes of phototransduction, somatosensory perception, acoustic and sonar detection. While all of these modalities have common elements (frequency, phase etc) the apparently enormous differences are not manifest in the cortical anatomy. Without knowledge of cerebral localization it is not easy (possible) to describe by purely anatomical/histological to which modality a particular piece of cortex belongs. There are always exceptions to this, of course, such as the whisker-to-barrel projection in the mouse and several other mammals including the kangaroos and wallabies. To emphasize this point a little further one can cause visual pathways to grow into different (eg auditory) cortical regions and still obtain what appear to be normal visual responses. Roger DuBois Institut d'Anatomie Faculte de Medicine LAUSANNE 1005 Switzerland From owner-neuroscience@net.bio.net Sun Aug 07 23:00:00 1994 Path: biosci!agate!usenet.ins.cwru.edu!eff!news.duke.edu!godot.cc.duq.edu!ddsw1!a2i!satlink!doctor!daniel From: daniel@doctor.satlink.net (Daniel R.) Newsgroups: bionet.neuroscience Subject: aids. neuropsichiatry psichofarmachology Message-ID: Date: Sun, 7 Aug 94 22:07:33 GMT X-Newsreader: -SatLink- 1.00 (Waffle 1.65) Lines: 0 From owner-neuroscience@net.bio.net Sun Aug 07 23:00:00 1994 Path: biosci!agate!barrnet.net!nntp.crl.com!crl.crl.com!not-for-mail From: raydavis@crl.com (Ray Davis) Newsgroups: bionet.neuroscience Subject: Re: Shaking hands during dissections Date: 8 Aug 1994 09:16:32 -0700 Organization: CRL Dialup Internet Access (415) 705-6060 [login: guest] Lines: 12 Distribution: world Message-ID: <325lp0$5mh@crl.crl.com> References: <31f0r9$jsq@nntp2.Stanford.EDU> <31gbov$16k@search01.news.aol.com> <31jtb6$l9t@lyra.csx.cam.ac.uk> <31m2on$c5m@gazette.bcm.tmc.edu> NNTP-Posting-Host: crl.com X-Newsreader: TIN [version 1.2 PL2] Artur Kania (ak990140@SPECIALK.IAIMS.BCM.TMC.EDU) wrote: : ... I find that a couple of strong beers before : dissecting usually do the trick. Really . One of the symptoms of essential tremor is that a small dose of alcohol will reduce the tremor. However, most physicians are reluctant to prescribe alcohol. (: >,) Ray From owner-neuroscience@net.bio.net Sun Aug 07 23:00:00 1994 Path: biosci!headwall.Stanford.EDU!rasch From: rasch@leland.Stanford.EDU (Christopher Michael Rasch) Newsgroups: bionet.neuroscience Subject: Tremor Remedies Date: 8 Aug 1994 22:12:05 GMT Organization: Stanford University, CA 94305, USA Lines: 41 Message-ID: <326ajl$1sp@nntp2.Stanford.EDU> NNTP-Posting-Host: elaine47.stanford.edu Hi all, Thanks to everyone who posted/e-mailed suggestions for reducing tremors during dissections. Below is a summary of the suggestions I received. 1. Rest forearms/wrist on a support (scope frame, sandbag, books, rubber pads) so that tremor is confined to that originating in the fingers, not the whole arm. The closer the tip of the instrument is to a point of stability, the less tremor there will be. Try holding the forceps only between the thumb and forefinger; don't rest it on the notch in between them. 2. Use your dominant hand to do all of the work; use subordinate hand to stabilize preparation. A number of people reported that bracing the dissecting arm with the other hand increased stability. 3. Avoid stimulants, particularly caffeine (coffee, tea, Mountain Dew, etc) the day of dissection. A number of people report decreased trembling after consuming a small amount of alcohol before the dissection. 4. If possible, time the dissection when you are well-rested and alert. Avoid weight-lifting, or heavy manual labor immediately before the dissection. Take breaks during long dissections. Arrange the layout of the scope and working area to avoid postural strain--no hunching, chin should be tucked in, not jutting out when looking into the microscope. Physical and mental fatigue increase trembling. 5. Sharp, high quality instruments make dissections much easier. Roboz Surgical Instrument Co. (202) 393-1234 manufactures microsurgical equipment. 6. With practice, most people report a decline in tremors. To practice, tie knots in fine suture (10-0 or smaller). Suture rubber bands together using fine suture. Cut and manipulate ultra-thin sections in electron microscopy lab. Anastamose the femoral artery of a rat. Chris Rasch From owner-neuroscience@net.bio.net Sun Aug 07 23:00:00 1994 Path: biosci!galaxy.ucr.edu!ihnp4.ucsd.edu!munnari.oz.au!yoyo.aarnet.edu.au!news.adelaide.edu.au!gateway.dircsa.org.au!cleese.apana.org.au!byron.apana.org.au!byron.apana.org.au!not-for-mail From: dbradley@byron.apana.org.au (David Bradley) Newsgroups: bionet.neuroscience Subject: Serotonin Replenished??? Date: 8 Aug 1994 22:45:34 +0930 Organization: Byron - cheap mail and news Lines: 8 Message-ID: <325b69$aur@hack.byron.apana.org.au> X-Newsreader: TIN [version 1.2 PL2] I was wondering if there have been *any* new research lately into the replenishent of serotonin in the brain. Thanks in return (and excuse me for my non-existent sig! - My first day with this acct.) From owner-neuroscience@net.bio.net Sun Aug 07 23:00:00 1994 Path: biosci!agate!usenet From: Randolph Hampton Newsgroups: bionet.neuroscience Subject: endorphins (or other peptides) and running Date: 8 Aug 1994 17:43:26 GMT Organization: UCBerkeley MCB Lines: 24 Distribution: world Message-ID: <325qru$dkq@agate.berkeley.edu> NNTP-Posting-Host: 128.32.177.131 X-UserAgent: Version 1.1.3 X-XXDate: Mon, 8 Aug 94 17:42:21 GMT Dear neuronetters I turn to this bullitin board to ask about a piece of popular physiological dogma. Everywhere you turn one sees/hears/ reads reference to the notion that running and/or other aerobic exercises bring about enough "enkephalinergic activity " to explain the colloquially described "runner's high". Granted its a nice idea, with all sorts of connected implications, but my question is, is there really any evidence (ie studies with antagonists, measurements of blood levels, animal models, etc. ) for this very popular hypothesis. please inform as you will, and/or add any thoughts or input. thanks, Randy Hampton ------------------------------------------------- Randolph Hampton 401 Barker Hall UC Berkeley MCB Dept Berkeley CA 94720 Phone: 510 642 7070 Fax: 510 642 6420 e mail: randy@mendel.berkeley.edu ------------------------------------------------- From owner-neuroscience@net.bio.net Sun Aug 07 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!usc!nic-nac.CSU.net!charnel.ecst.csuchico.edu!psgrain!nntp.cs.ubc.ca!torn!uunet.ca!uunet.ca!io.org!nobody From: michelbo@io.org (Michel Bordeleau) Newsgroups: bionet.neuroscience Subject: Re: Skatchard Analysis on the mac? Date: 7 Aug 1994 22:36:18 -0400 Organization: Internex Online (io.org) Data: 416-363-4151 Voice: 416-363-8676 Lines: 23 Message-ID: <3245n2$4ab@ionews.io.org> References: NNTP-Posting-Host: nudge.io.org In article , Jason L. Buberel wrote: >Neuroscientists, > >Would anyone out there like to reccomend a mac (preferably PowerMac) >software that will do a Skatchard analysis? If it will support multiple >binding sites/receptor subtypes, that would be great. > Hi... We used to use MacLigand by Munson before we swtiched over to the PC version of the program (and subsequently to Accufit by Lundon). Ligand is available free of charge from Munson at NIH. I do not have the address with me at home, but I'm sure either someone else will be able to give it to you, or failing that, let me know and I'll dig it up at work. BTW, Ligand is one of the most popular data analysis programs, or so I've been told. Michel From owner-neuroscience@net.bio.net Mon Aug 08 23:00:00 1994 Path: biosci!bcm!news.msfc.nasa.gov!europa.eng.gtefsd.com!swiss.ans.net!newstf01.cr1.aol.com!search01.news.aol.com!not-for-mail From: footc@aol.com (Foot C) Newsgroups: bionet.neuroscience Subject: Ear Lobe Date: 8 Aug 1994 20:31:15 -0400 Organization: America Online, Inc. (1-800-827-6364) Lines: 13 Sender: news@search01.news.aol.com Message-ID: <326ioj$n7f@search01.news.aol.com> NNTP-Posting-Host: search01.news.aol.com We are having a debate over the ear lobe. Can you settle a bet? Is the pina of the ear somatotopic or not? A recent study on reflexology says it is. We don't think so. But we need an expert. Thanks in advance. Kevin Kunz Reflexology Research ********************************************************* "All acts of life both conscious and unconscious are reflexes." IM Sechenov- 1829-1905- Pavlov's teacher ********************************************************** From owner-neuroscience@net.bio.net Mon Aug 08 23:00:00 1994 Path: biosci!bcm!cs.utexas.edu!convex!news.duke.edu!concert!bigblue.oit.unc.edu!not-for-mail From: Jimmy.Zhang@launchpad.unc.edu (Jimmy Zhang) Newsgroups: bionet.neuroscience Subject: Looking for a male roommate for Neuroscience Meeting, Miami Date: 8 Aug 1994 19:46:49 -0400 Organization: University of North Carolina Extended Bulletin Board Service Lines: 17 Sender: bbs@lambada.oit.unc.edu Distribution: world Message-ID: <326g59$mte@lambada.oit.unc.edu> NNTP-Posting-Host: lambada.oit.unc.edu X-Disclaimer: LaUNChpad is an experiemental BBS. X-Disclaimer: The views of its users X-Disclaimer: do not necessarily represent those of either X-Disclaimer: OIT, the SysOps, or Charlie Gaddy. Thanks. I am looking for a roommate to share a hotel room during the Neuroscience Annual meeting, which will be held in Miami Beach, Florida from November 13-18, 1994. If you're interested in, please reply me at 214-648-2347 (lab) or zhang03@utsw.swmed.edu. Thank you! P.S. I am a graduate student. If you're also a graduate student and would like to take advantage of the low student rate, please reply to me as soon as possible, since the deadline is 8/31. -- Jimmy -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- Launchpad is an experimental internet BBS. The views of its users do not necessarily represent those of UNC-Chapel Hill, OIT, or the SysOps. -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- From owner-neuroscience@net.bio.net Mon Aug 08 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!europa.eng.gtefsd.com!newsxfer.itd.umich.edu!uunet!newstf01.cr1.aol.com!search01.news.aol.com!not-for-mail From: chipstein@aol.com (Chipstein) Newsgroups: bionet.neuroscience Subject: Re: Home built EEG Date: 8 Aug 1994 23:09:03 -0400 Organization: America Online, Inc. (1-800-827-6364) Lines: 28 Sender: news@search01.news.aol.com Message-ID: <326s0f$q51@search01.news.aol.com> References: NNTP-Posting-Host: search01.news.aol.com In article , sjacobs@maroon.tc.umn.edu (Steve Jacobson) writes: >I am building an EEG machine and intend to digitize the amplified analog signals for input into a computer. I am considering using a 16 bit A/D for each channel. The question I have is: Is a 16 bit A/D overkill? Is 12 bits sufficient. What kind of voltage range am I liable to encounter on the EEG electrodes? I intend to use isolation devices between the front-end processor and the main computer. 16 bits is definitely overkill, since an average scalp EEG is about 50 uV peak-to-peak and the noise is around 2 uV. Although 12 bit resolution is nice, I have done a lot of research with an ancient 8-bit A/D. Isolation is necessary only if you plan to study patients connected to intravenous lines or gadgets, or if for some reason the subjects can't be kept away from earth ground. Noise is in fact the main problem. In addition to a good high-impedance instrumentation amplifier, you should boost the analog signal out of the millivolt range to avoid noise generated by the computer. ________________________________ Charles M. Epstein, M.D. Emory University From owner-neuroscience@net.bio.net Mon Aug 08 23:00:00 1994 Path: biosci!bcm!news.msfc.nasa.gov!europa.eng.gtefsd.com!emory!news.cc.emory.edu!news.cc.emory.edu!not-for-mail From: bioaw124@emoryu1.cc.emory.edu (Claire Maier) Newsgroups: bionet.neuroscience Subject: Re: Shaking hands during dissections Date: 8 Aug 1994 20:19:13 -0400 Organization: Emory University Lines: 17 Distribution: world Message-ID: <326i21$39s@emoryu1.cc.emory.edu> References: <31f0r9$jsq@nntp2.Stanford.EDU> <31gbov$16k@search01.news.aol.com> <31jtb6$l9t@lyra.csx.cam.ac.uk> <31m2on$c5m@gazette.bcm.tmc.edu> <325lp0$5mh@crl.crl.com> NNTP-Posting-Host: emoryu1.cc.emory.edu X-Newsreader: TIN [version 1.2 PL2] Ray Davis (raydavis@crl.com) wrote: : Artur Kania (ak990140@SPECIALK.IAIMS.BCM.TMC.EDU) wrote: : : ... I find that a couple of strong beers before : : dissecting usually do the trick. Really . : One of the symptoms of essential tremor is that a small dose of alcohol : will reduce the tremor. : However, most physicians are reluctant to prescribe alcohol. (: >,) Enhanced physiologic tremor (which is what the tremor during dissection probably is, if tremor is not present at other times) also responds to small amounts of alcohol. But what doctors do prescribe is propanolol. If not contraindicated (for asthma or some other condition), it can be taken for essential tremor, enhanced physiological tremor, or even conditions such as stage fright. From owner-neuroscience@net.bio.net Mon Aug 08 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!news.cac.psu.edu!news.tc.cornell.edu!travelers.mail.cornell.edu!newsstand.cit.cornell.edu!news.graphics.cornell.edu!ghost.dsi.unimi.it!univ-lyon1.fr!swidir.switch.ch!cisun2000.unil.ch!news From: "Nouchine Hadjikhani" Newsgroups: bionet.neuroscience Subject: Re: Tourette Syndrome Date: Tue, 9 Aug 94 17:20:27 CDT Organization: University of Lausanne CH (Switzerland) Lines: 31 Message-ID: <3286rs$895@cisun2000.unil.ch> NNTP-Posting-Host: pcphysioa_porta.unil.ch To: "Maurizio MORABITO; Tel.6661" In-Reply-To: Your message of Wed, 3 Aug 1994 04:31:49 GMT. Encoding: 8 TEXT , 22 MESSAGE There is a whole book written on Tourette: It is called "Gilles de la Tourette syndrome", and is written by A.Shapiro, E.Shapiro, R.Bruun and R. Sweet. It is published by Raven Press, New York. On coprolalia, they say that it develops in about 55% of the patients, with an average age at onset of 13.5 years.It is usually not the first symptom to occur, but it is usually the first to diappear with chemotherapy. It is not an essential characteristic of the syndrome, but its presence confirms it. N.Hadjikhani, MD Newsgroups: bionet.neuroscience Path: cisun2000.unil.ch!swidir.switch.ch!newsfeed.ACO.net!Austria.EU.net!EU.net!uunet!news.iij.ad.jp!wnoc-tyo-news!news.u-tokyo.ac.jp!news.tisn.ad.jp!aist.go.jp!ripspost!b0017 From: b0017@nibh.go.jp (Maurizio MORABITO; Tel.6661) Subject: Tourette Syndrome Message-ID: Sender: news@aist.go.jp Nntp-Posting-Host: 150.29.56.34 Organization: National Institue of Bioscience and Human-Technology(NIBH), Japan. Date: Wed, 3 Aug 1994 04:31:49 GMT Lines: 10 Hi all! I am looking for refs about the Tourette Syndrome, particularly about the "coprolalia" (Dirty language) effect. Is there anybody that can help me please? thanks maurizio -- Maurizio Morabito maurizio@nibh.go.jp From owner-neuroscience@net.bio.net Mon Aug 08 23:00:00 1994 Newsgroups: bionet.neuroscience Path: biosci!agate!library.ucla.edu!europa.eng.gtefsd.com!newsxfer.itd.umich.edu!uunet!newsflash.concordia.ca!sifon!news From: BOUYER@medcor.mcgill.ca (BOUYER, LAURENT(PHYSIOANAESTHE) Subject: Smooth muscle Message-ID: <1994Aug9.135149.13650@sifon.cc.mcgill.ca> Sender: news@sifon.cc.mcgill.ca Organization: McGill University Faculty of Medicine Date: Tue, 9 Aug 1994 13:51:49 GMT X-News-Reader: VMS NEWS v1.25 Lines: 13 Would someone know if any type of smooth muscle contains muscle spindles? If so could you direct me to a textbook or journal article? I need this info for teaching purposes... :-) Thanks Laurent Bouyer Aerospace Medical Research Unit McGill University, Montreal From owner-neuroscience@net.bio.net Mon Aug 08 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!EU.net!Germany.EU.net!netmbx.de!zib-berlin.de!rs1-hrz.uni-duisburg.de!news.rz.uni-duesseldorf.de!usenet From: "" Newsgroups: bionet.neuroscience Subject: K+-sensitive-glass-wanted Date: Tue, 9 Aug 94 15:57:53 +0100 Organization: Heinrich Heine Universitaet Duesseldorf Lines: 11 Message-ID: <27983.kilb@mail.rz.uni-duesseldorf.de> NNTP-Posting-Host: 134.99.200.87 X-Minuet-Version: Minuet1.0_Beta_9 X-POPMail-Charset: German Is there anyone out there who posseses K+-sensitive- glass and can give a few kapillares to us. We need the glass for a experiment for undergraduate students. Since this experiment took place only this semester it will be unreasonable for us to buy this glass. kilb@mail.uni-duesseldorf.de W.Kilb Inst. f. Zoologie 1/Neurobiol. H-Heine-Universitaet 40225 Duesseldorf Germany From owner-neuroscience@net.bio.net Mon Aug 08 23:00:00 1994 Newsgroups: bionet.neuroscience Path: biosci!rutgers!uwvax!sinetnews!news.u-tokyo.ac.jp!news.tisn.ad.jp!riksun!rknss1!rkna50!cateau From: cateau@murasaki.riken.go.jp (Hideyuki Cateau) Subject: Info on Epilepsy wanted Message-ID: <1994Aug9.095651.3229@rkna50.riken.go.jp> Followup-To: poster Sender: news@rkna50.riken.go.jp (News Administrator) Nntp-Posting-Host: aoi Organization: Laboratory for Neural Networks X-Useragent: NewsAgent v1.482 Date: Tue, 9 Aug 1994 09:56:51 GMT Lines: 12 Hi, Netters: I am interested in a quantitative characterization of Epilepsy. I heard that a patient of epilepsy generally experience various degrees of seizure, from micro seizure to big one. In this respect, I am interested in the frequency distribution of seizures. Generally it is expected that there are many small seizures occurring and there are a little big seizures. But, I would like to know more detailed frequency distribution from the theoretical point of view. If any of you tell me some information on this problem, I would greatly appreciate it. H.Cateau From owner-neuroscience@net.bio.net Mon Aug 08 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!gatech!newsxfer.itd.umich.edu!uunet!newstf01.cr1.aol.com!search01.news.aol.com!not-for-mail From: est812@aol.com (EST812) Newsgroups: bionet.neuroscience Subject: Re: Vaso-vagal Syncope Date: 9 Aug 1994 01:38:09 -0400 Organization: America Online, Inc. (1-800-827-6364) Lines: 10 Sender: news@search01.news.aol.com Message-ID: <3274o1$svv@search01.news.aol.com> References: <2t3fo2$com@search01.news.aol.com> NNTP-Posting-Host: search01.news.aol.com In article <2t3fo2$com@search01.news.aol.com>, wboonn@aol.com (WBoonn) writes: >I am an undergraduate student ..... research on vaso-vagal syncope ..... It is my understanding that this reaction is an evolutionary vestige, presumably a variant of the "fight or flight response." Having seen blood spilled either from one's self or another, a rapid "shut-down" occurs, supposidly to reduce the potential blood loss perhaps to allow time to let coagulation occur. From owner-neuroscience@net.bio.net Tue Aug 09 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!pipex!uknet!news.cranfield.ac.uk!xdm090.ccc.cranfield.ac.uk!ea932783 From: ea932783@xdm090.ccc.cranfield.ac.uk (A.R.LAWSON) Newsgroups: bionet.neuroscience Subject: head injury research Date: 10 Aug 1994 14:07:43 GMT Organization: Cranfield University, UK Lines: 2 Distribution: world Message-ID: <32amvf$2ba@xdm001.ccc.cranfield.ac.uk> NNTP-Posting-Host: xdm090.pegasus.cranfield.ac.uk Keywords: Head injury, finite element Is there anyone who can assist From owner-neuroscience@net.bio.net Tue Aug 09 23:00:00 1994 Newsgroups: bionet.neuroscience Path: biosci!agate!howland.reston.ans.net!cs.utexas.edu!usc!nic-nac.CSU.net!charnel.ecst.csuchico.edu!csusac!csus.edu!netcom.com!starin From: starin@netcom.com (Jeffrey Starin) Subject: Hemispheric Dominance Message-ID: Organization: NETCOM On-line Communication Services (408 261-4700 guest) X-Newsreader: TIN [version 1.2 PL1] Date: Tue, 9 Aug 1994 23:59:43 GMT Lines: 8 Would anyone know of a simple test to determine which hemisphere of the brain is dominant? I understand that handedness does not always correspond to it's *opposite* side to prove hemispheric dominance. Jeffrey {New York} -- Jeffrey {New York} From owner-neuroscience@net.bio.net Tue Aug 09 23:00:00 1994 Path: biosci!agate!ihnp4.ucsd.edu!news.service.uci.edu!phar2.medsurge.hsis.uci.edu!user From: mwspitze@uci.edu (matt spitzer) Newsgroups: bionet.neuroscience Subject: Re: Ear Lobe Followup-To: bionet.neuroscience Date: Tue, 09 Aug 1994 21:43:29 -0800 Organization: lacking Lines: 16 Message-ID: References: <326ioj$n7f@search01.news.aol.com> NNTP-Posting-Host: phar2.medsurge.hsis.uci.edu In article <326ioj$n7f@search01.news.aol.com>, footc@aol.com (Foot C) wrote: > We are having a debate over the ear lobe. Can you settle a bet? Is the > pina of the ear somatotopic or not? A recent study on reflexology says it > is. We don't think so. But we need an expert. Yes. Take it from me, an auditory physiologist, the pinna is a map of the body, not a specialization for hearing as some completely insane people have suggested. Consider a comparative approach. If the shape of the pinna is related to auditory function one would expect that animals with the best hearing would have the biggest pinnae. Ever see ears on a barn owl? I should say not! Now consider the alternative hypothesis, that the pinna is a map of the body. Everyone knows that the triangular shape of the cat's pinnae mirrors the triangular shape of its body, and what about the long sleek pinnae of the dolphin? I think it's pretty obvious. From owner-neuroscience@net.bio.net Tue Aug 09 23:00:00 1994 Newsgroups: bionet.neuroscience Path: biosci!agate!howland.reston.ans.net!torn!nott!cunews!ataylor From: ataylor@superior.carleton.ca (alex taylor) Subject: Re: Hemispheric Dominance Message-ID: Sender: news@cunews.carleton.ca (News Administrator) Organization: Carleton University, Ottawa, Canada References: Date: Wed, 10 Aug 1994 02:58:19 GMT Lines: 15 In article , Jeffrey Starin wrote: >Would anyone know of a simple test to determine which hemisphere of the >brain is dominant? I understand that handedness does not always >correspond to it's *opposite* side to prove hemispheric dominance. For task specific questions, sodium amytal injections into the carotid artery have been used by D. Kimura and others. PET scanners have also been used. None of these are really simple, or without some risk to the subject, however. As far as I am aware there is no general simple way to determine overall hemispheric dominance. Generally hemispheric dominance seems to be assessed with respect to a specific cognitive function (eg. language, handedness, visual processing). From owner-neuroscience@net.bio.net Tue Aug 09 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!europa.eng.gtefsd.com!news.uoregon.edu!netnews.nwnet.net!news.u.washington.edu!Eli.Meir From: meir@zoology.washington.edu (Eli Meir) Newsgroups: bionet.neuroscience Subject: Circuit Diagram of Manduca Flight? Date: 10 Aug 1994 03:41:23 GMT Organization: Dept. of Zoology, Univ. of Washington Lines: 10 Sender: -Not-Authenticated-[3641] Message-ID: <329i93$dfr@news.u.washington.edu> NNTP-Posting-Host: quaternary.zoology.washington.edu X-Posted-From: InterNews 1.0@news.u.washington.edu. Xdisclaimer: No attempt was made to authenticate the sender's name. I'm looking for good references on the control of flight muscles in Manduca, including the role of sensory feedback. Particularly useful would be some sort of 'circuit diagram' of the part of the nervous system controlling flight. Thanks in advance Eli Meir Dept of Zoology, Univ of Washington meir@zoology.washington.edu From owner-neuroscience@net.bio.net Tue Aug 09 23:00:00 1994 Path: biosci!agate!darkstar.UCSC.EDU!orchid.UCSC.EDU!mintz From: mintz@orchid.UCSC.EDU (Eric Mintz) Newsgroups: bionet.neuroscience Subject: Re: more dolphin sleep (%24hr) Date: 10 Aug 1994 04:01:33 GMT Organization: UC Santa Cruz Lines: 41 Distribution: world Message-ID: <329jet$jtf@darkstar.UCSC.EDU> References: NNTP-Posting-Host: orchid.ucsc.edu One question which I don't think has been adequately addressed is the question of whether REM sleep exists in dolphins. Since REM sleep results in muscle atonia, and dolphins are continuously swimming, perhaps it is not surprising that they show no overt evidence of REM sleep. However, my own observations of the pigeon lead me to believe that the existence of REM sleep may be easy to miss. In pigeons, REM sleep last for as little as 3 seconds at a time. I would hypothesize that perhaps this is an adaptation for remaining on an unsteady perch while sleeping. You propose that sleep represents some critical aspect of our physiology, and is not simply an evolutionary adaptation. Keeping in mind that by definition it must be some kind of adaptation, there are several lines of evidence which indicate that sleep is not, at least by definition, a critical process. The amount of sleep required by individuals is extremely variable - some individuals are capable of functioning perfectly normally on one hour or less of sleep per day (I speak of humans), perhaps indicating a lack of any strong selective pressure. Pigeons can be completely sleep deprived for over a month simply by keeping them in conditions of continuous light, and yet they show no overt ill effects, and show no sleep "rebound" after being returned to darkness. In fact, some researchers would even claim that dolphins aren't really sleeping at all while showing the unihemispheric slow wave activity (Personally, I do think they are sleeping - this is for discussion's sake). In their minds, if the dolphins are swimming and showing such coordinated movements in a social group than by definition they are not asleep. There is also precedent for high levels of slow wave activity during waking, as this is quite common in birds. I am not saying that sleep is not a critical physiological process in some cases, only that we should be cautious before trying to generalize about the properties of sleep across different species. Eric -- Eric Mintz | "Run! Seek Shelter! The 7-year dung Department of Biology | frogs are migrating!" University of California, Santa Cruz | -- Robotman (actually, his tour guide) From owner-neuroscience@net.bio.net Tue Aug 09 23:00:00 1994 Path: biosci!galaxy.ucr.edu!ihnp4.ucsd.edu!news.service.uci.edu!phar2.medsurge.hsis.uci.edu!user From: mwspitze@uci.edu (matt spitzer) Newsgroups: bionet.neuroscience Subject: Re: Inhibition and Maturation Followup-To: bionet.neuroscience Date: Tue, 09 Aug 1994 21:20:11 -0800 Organization: lacking Lines: 16 Message-ID: References: <31tcp8$sl1@portal.gmu.edu> NNTP-Posting-Host: phar2.medsurge.hsis.uci.edu In article <31tcp8$sl1@portal.gmu.edu>, herwin@mason1.gmu.edu (HARRY R. ERWIN) wrote: > > 3. Anxiety often becomes milder during adolescence as the nervous system > (particularly the GABAergic component) matures. Whoa there! Don't you think that making inferences about mental states from data on cellular functions of GABA receptors is a bit of a cognitive leap? Also, the changes that have been documented in GABA mediated psps take place in the first post-natal week in rats. I don't know how maturation in humans correlates with that in rats, but I'd guess that the developmental events we are talking about would probably be taking place during infancy or prenatally. From owner-neuroscience@net.bio.net Tue Aug 09 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!pipex!uknet!news.cranfield.ac.uk!xdm090.ccc.cranfield.ac.uk!ea932783 From: ea932783@xdm090.ccc.cranfield.ac.uk (A.R.LAWSON) Newsgroups: bionet.neuroscience Subject: Head Injury Research Date: 10 Aug 1994 14:18:33 GMT Organization: Cranfield University, UK Lines: 17 Distribution: world Message-ID: <32anjp$2ba@xdm001.ccc.cranfield.ac.uk> NNTP-Posting-Host: xdm090.pegasus.cranfield.ac.uk Keywords: Head Injury, Finite Element Analysis Is there anyone out there who could provide informatiom that will assist me in developing a 3-D finite element model of the head complex. The model is to be used to examine closed-rotational injuries including DAI, gliding contusions and bridging vein disruption. Information that will provide any assistance would be greatly appreciated. The various elements are; 1. Anatomical and material property details 2. Tissue failure information, including important regional and critical field parameter details 3. Clinical consequences of various injury regions Thank you in advance Mr A.R. Lawson Research Student SME Cranfield University MK43 OAL Email: A.R.Lawson@Cranfield.ac.uk Tel : +44 (0) 234 754708 Fax : +44 (0) 234 750728 From owner-neuroscience@net.bio.net Tue Aug 09 23:00:00 1994 Path: biosci!bcm!cs.utexas.edu!swrinde!news.dell.com!dellgate.us.dell.com!amotz From: amotz@dellgate.us.dell.com (Andy Motz) Newsgroups: bionet.neuroscience Subject: syncope/loc and varicella Date: 10 Aug 1994 21:18:56 GMT Organization: Dell Computer Corporation Lines: 7 Message-ID: <32bg80$8ju@uudell.us.dell.com> NNTP-Posting-Host: dellgate.us.dell.com Although it is something of a moot point at this point (life is irrevocably changed already) does anyone know of any relation between varicella and losses-of-consciousness? I am particularly interested in pre-eruptive loc (anywhere from 10-17 days)? Thanks in advance. Andy amotz@dellgate.us.dell.com From owner-neuroscience@net.bio.net Tue Aug 09 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!EU.net!Germany.EU.net!news.dfn.de!urmel.informatik.rwth-aachen.de!news.rhrz.uni-bonn.de!thomas From: thomas@jersey.meb.uni-bonn.de (Thomas Grunwald) Newsgroups: bionet.neuroscience Subject: Q: nestin human antibody Date: 10 Aug 1994 09:38:00 GMT Organization: Bonn University - Clinic of Epileptology Lines: 14 Distribution: world Message-ID: <32a75p$27v@news.rhrz.uni-bonn.de> NNTP-Posting-Host: jersey_tr.meb.uni-bonn.de I am looking for a commercially available nestin antibody. There was a rumour that a California-based firm had developed such an antibod. Does anyone have a contact address or is even working with a commercially available antibody? Heinz -------- Dr.med. Dr. phil. Thomas Grunwald / University Clinic of Epileptology Sigmund-Freud Str. 25 / 53105 Bonn / Germany phone: 0228 - 287 5864 / fax: 0228 - 287 6294 email: thomas@jersey.meb.uni-bonn.de From owner-neuroscience@net.bio.net Tue Aug 09 23:00:00 1994 Path: biosci!agate!doc.ic.ac.uk!daresbury!trane.uninett.no!eunet.no!nuug!EU.net!uunet!munnari.oz.au!newsroom.utas.edu.au!clinicals101h68.med.utas.edu.au!user From: Dallas.Grasby@path.utas.edu.au (Dallas Grasby) Newsgroups: bionet.neuroscience Subject: more dolphin sleep (%24hr) Followup-To: bionet.neuroscience Date: Wed, 10 Aug 1994 11:16:42 +1000 Organization: neurobiology.pathology.UTAS Lines: 75 Distribution: world Message-ID: NNTP-Posting-Host: clinicals101h68.med.utas.edu.au Excerpts from "Sleep in marine mammals" L.M. Mukhametov Experimental Brain Research Supplement 8...... "Unihemispheric slow wave sleep is the main type of sleep in the dolphin brain. The synchronized EEG patterns in one hemisphere may be accompanied by a desynchronized pattern in the other. The intermediate EEG synchronization (stage 2) could be observed both bilaterally and unilaterally. Delta sleep (stage 3) in dolphins can only be unihemispheric. We have never recorded bilateral delta waves in dolphin brain during natural sleep. Unilateral sleep episodes can last more than 2h." The author stresses "natural" sleep because bilateral delta waves can be evoked by certain pharmacological agents such as Diazepam. "Unihemispheric sleep was observed in all dolphins of the two species (21 bottlenose dolphins and 9 porpoises), in which the electrodes were implanted in both hemispheres. The state with the asynchrony of EEG slow waves in the two hemispheres occupied about 30%-40% of recording time. Simultaneous recordings from the parietal, occipital, and frontal fields of the hemisphere confirm that a hemisphere is always synchronized or desynchronized as a unit. Records from thalamic nuclei demonstrate that the thalamus can also generate slow wave activity unilaterally and concurrently with ipsilateral neocortex. Thus, unilateral slow wave sleep is not only a cortical, but also a subcortical phenomenon." Mukhametov provides a figure in this paper which indicates the time that each hemisphere spends in each stage of sleep over a 24hr period. 7 periods of unilateral delta synchronization are indicated giving a total of about 4 hours (about 2 hours a hemisphere). The sleep times for the two hemispheres is commonly unequal, but while individuals may demonstrate a particular cerebral dominance with respect to sleep, there seems no pattern of left or right dominance that is uniform across the species. It has been observed that "sleeping" dolphins will have either one or two eyes open at any time and that there appears to be no correlation with which hemisphere is wakeful. Observations of the optic chiasm in dolphins (Jacobs MS, Morgane PJ, Mcfarland WL, (1975) Degeneration of the visual pathways in the bottlenose dolphin. Brain Res 88:346-352) suggest that its complete decussation allows either eye to act as a "sentinel" eye during hemispheric sleep. Investigations of sleep in seals is interesting too. One study of the Cape fur seal (Arctocephalus pusillus) found that across a 24hr recording time, 4.6% of this time was spent in paradoxical sleep (absent in dolphins) and 27.4% was spent in slow-wave sleep. 40% of the latter slow-wave sleep was demonstrated to be unilateral. (Lyamin OI, Chetyrbok IS, (1992) Neurosci Letters 143:263-). A study of northern fur seals (Callorhinus ursinus) showed that "the relative amount of interhemispheric slow wave asymmetry was higher during sleep in water comparing to that on land" (Liamin OI, Mukhametov LM, Poliakova IG, (1986) Zh Vyssh Nerv Deiat 36(6):1039-). When sleeping at the water surface, these seals are observed to maintain their position by using just one of their flippers. Some of the interesting mail to bionet.neuroscience that has appeared recently on dolphins and split brains has wondered how much circuitry (if any) must be duplicated in a unilateral sleeper. Probably tricks like these of the seal and adaptations involving the decussation of sensory afferents (as with dolphin vision above) allow a 'lone' hemisphere to tackle the problems of sleep in a marine environment without duplication. I'd be interested in what kinds of functional asymmetries exist in the brains of these animals and see how the temporary absence of a unilateral function is reconciled during unihemispheric sleep eg Can a unilaterally sleeping dolphin produce 'meaningful' vocalizations and respond to other dolphin signals in a normal way? I think that these observations of sleep in the marine mammals further suggest that sleep isn't just an evolutionary adaptation but a critical aspect of our physiology. I've heard that one blind species of marine mammal has adapted to a particularly harsh environment (one where the opportunity to sleep is severely compromised) by sleeping in 90 second periods throughout the day, and clocks up a total of 7 hours sleep every 24! The same conditions that let vision slip from the species' physiological repertoire, couldn't stifle the physiological requirement for sleep. From owner-neuroscience@net.bio.net Tue Aug 09 23:00:00 1994 Path: biosci!bcm!cs.utexas.edu!howland.reston.ans.net!swiss.ans.net!newstf01.cr1.aol.com!search01.news.aol.com!not-for-mail From: dsaussy@aol.com (DSaussy) Newsgroups: bionet.neuroscience Subject: Re: Looking for references to pA2 Date: 10 Aug 1994 18:34:15 -0400 Organization: America Online, Inc. (1-800-827-6364) Lines: 12 Sender: news@search01.news.aol.com Message-ID: <32bkl7$8ho@search01.news.aol.com> References: <30h4bg$jj4@mserv1.dl.ac.uk> NNTP-Posting-Host: search01.news.aol.com In article <30h4bg$jj4@mserv1.dl.ac.uk>, Sistemi Cellulari writes: <> You might also want to try Terry Kenakin's textbook "Pharmacologic Analysis of Drug-Receptor Interaction" (2nd ed. Raven Press, 1993) for an in depth explanation of pA2 and other methods of quantitative analysis of ligand-receptor interactions. From owner-neuroscience@net.bio.net Tue Aug 09 23:00:00 1994 Path: biosci!agate!howland.reston.ans.net!cs.utexas.edu!convex!news.duke.edu!solaris.cc.vt.edu!swiss.ans.net!newstf01.cr1.aol.com!search01.news.aol.com!not-for-mail From: dsaussy@aol.com (DSaussy) Newsgroups: bionet.neuroscience Subject: Re: Skatchard Analysis on the mac? Date: 10 Aug 1994 18:48:01 -0400 Organization: America Online, Inc. (1-800-827-6364) Lines: 15 Sender: news@search01.news.aol.com Message-ID: <32blf1$8op@search01.news.aol.com> References: NNTP-Posting-Host: search01.news.aol.com In article , jbuberel@uiuc.edu (Jason L. Buberel) writes: <> Somewhere out there is a version of LIGAND for the Mac called MacLigand which will do multiple site fitting using iterative nonlinear regression (much better than Scatchard, Rosenthal, etc.). You could also write equations in Excel to do this, or try the great statistics/data visualization program JMP (SAS Institute, Cary NC). Another good alternative (if its still available) is MultiFit from Day Computing in Cambridge, UK. If you have questions about my experience with any of these packages, contact me by phone @ 919-990-5061 or e-mail @ saussy~dl@glaxo.com. David From owner-neuroscience@net.bio.net Wed Aug 10 23:00:00 1994 Path: biosci!agate!spool.mu.edu!darwin.sura.net!nntp.st.usm.edu!whale.st.usm.edu!rbateman From: rbateman@whale.st.usm.edu (Robert Bateman) Newsgroups: bionet.neuroscience Subject: ELISA for TRH Date: 11 Aug 1994 13:56:23 GMT Organization: University of Southern Mississippi Lines: 8 Message-ID: <32dam7$l8c@server.st.usm.edu> NNTP-Posting-Host: whale.st.usm.edu X-Newsreader: TIN [version 1.2 PL1] Has anyone used an ELISA for TRH? There is one published, but everyone seem