From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Path: biosci!news.stanford.edu!logbridge.uoregon.edu!fu-berlin.de!cijadra.dialup.fu-berlin.DE!not-for-mail From: cijadra@zedat.fu-berlin.de (Cijadrachon) Newsgroups: bionet.neuroscience Subject: Re: Dolphin brain Date: Mon, 01 Feb 1999 00:56:01 GMT Organization: Freie Universitaet Berlin Lines: 46 Message-ID: <36b4f551.23958559@news.zedat.fu-berlin.de> References: NNTP-Posting-Host: cijadra.dialup.fu-berlin.de (130.133.216.34) Mime-Version: 1.0 Content-Type: text/plain; charset=iso-8859-1 Content-Transfer-Encoding: 8bit X-Access: 16 17 18 X-Trace: fu-berlin.de 917914631 15099 (none) 130.133.216.34 X-Newsreader: Forte Free Agent 1.11/16.235 >The fact that you are writing this post is ample evidence that >intelligence has in fact increased; humans of 50-200,000 years ago were >completely incapable of this behavior or this level of analysis in any >way; How do you know that, did you teach one from then writing and reading as a child and educated that person similar to the way you were educated? >they would score lower on any intelligence test, even one that was >designed for them. FOR them? BY them should be the correct one. If I were to make a practical one for you (plural) I'd give you sticks and stones and flint stones and ask you to make tools out of them, and maybe send you into the forest without anything on you and observe who is more intelligent in surviving. And if we were in the past, so that here no damage could be done, go akasha surfing with all involved brains, as there I perceive a lot about different capacities. >There is no legimate intelligence defintion you could >use which would not give you that humans today are more intelligent. I might drop all involved naked into different natural areas and afterwards give them some magic tasks, and I would not be sure who is better. And what if I believe that no one truely intelligent would pollute water, and measure intelligence among other aspects by how much beings destroy and how much they protect environments for which their systems are naturally programmed? > I could take two identical twins, raise one in an isolated Just that no one said that back them they grew up as isolated as today some Westie kids are, or some adults are, some of whom then might kill themselves. >impoverished prison, and the other at Oxford, and the Oxford raised twin >would be MUCH MORE intelligent than the one raised in a prison. If you raised him in a like here, depending on the folks there, I would not be sure who would be more intelligent in the end. >Some traits areas >that contribute intelligence are heritable From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Path: biosci!news.stanford.edu!logbridge.uoregon.edu!fu-berlin.de!cijadra.dialup.fu-berlin.DE!not-for-mail From: cijadra@zedat.fu-berlin.de (Cijadrachon) Newsgroups: bionet.neuroscience Subject: Re: Dolphin brain Date: Mon, 01 Feb 1999 00:55:56 GMT Organization: Freie Universitaet Berlin Lines: 77 Message-ID: <36b4ddee.17971844@news.zedat.fu-berlin.de> References: <19990123184419.27486.00001075@ngol03.aol.com> NNTP-Posting-Host: cijadra.dialup.fu-berlin.de (130.133.216.34) Mime-Version: 1.0 Content-Type: text/plain; charset=iso-8859-1 Content-Transfer-Encoding: 8bit X-Access: 16 17 18 X-Trace: fu-berlin.de 917914627 15099 (none) 130.133.216.34 X-Newsreader: Forte Free Agent 1.11/16.235 (SKIP to certain people.) >>| Dolphins may possess a primitive language, this is debatable. More as a joke: Maybe they believe the same about you. ;-) > But, they are not capable of remembering how to avoid the fish nets, Do they get caught repeatedly? >A child can tell another child that a stove is hot. Also if the child did not try himself and does not have a word for stove? Also if I get out of something and I like games, then maybe I consider it some weird game not really dangerous since I am still there and not too much harmed and if I do not get out then maybe I cannot tell another. >No. Development of language may be indicative of intelligence. So if Broca's language center in your brain is damaged and your language capacities get very limited, then this is indicative of your intelligence? > It would be difficult to describe an individual human born without the necessary brain >anatomy to utilize language in some fashion as intelligent. And if I could draw well or me and the other were a good telepaths? >Communication is a valuable ability. But, I did not equate communication with language. :-) >(...) This form of communication is not considered a language. Languages are vocal or symbolic in some form, and >allow the transfer of complex ideas. Compare how much akasha / physics knowledge people good in such can transfer magically (especially with some sense enhancers) and how much with language, say within 4h to someone not knowing much about such stuff. What do you notice? I'd say for some areas magic communication allows the transfer of data within hours that with words I might not be able to transfer in a life time. Also apart from sense censored Westies most into magic never seemed to have had the idea to use much words for such areas, and to me that also seems rather uneffective in many areas. I do not know how dolphins chat, but what I heard on a tape sounded ways close to the old magic communication than to the new word communication. But not like human magic one. Just more related to that than to words. But that was just my fleeting impression. >Do we assign the vicious growling of a dog to language? I think not. Nice you think not for we. (BTW, there was a cool ad once on T.V. where a child and a dog where in telepathic communication. Beautiful, and interesting. Wonder how much CAN be transferred via T.V. But then again maybe it is not wise to wonder about that too much. ;-) > Its communication goal is purely instinctive. THE generalized dog? Actually a lot of humans communication goals seem rather instinctive to me. For some reason I have to think of some German joke. Ein Mann, ein Wort. Eine Frau, ein Woerterbuch. >The dance of the honey bee can communicate the location of nectar. But, this is >not language. This is the communication of a concrete fact, not complex >ideas. Ah, so the communication of concrete facts is not language. > Great apes and humans can communicate complex ideas. Yes, if I look out of the window there are a lot of the results of it, "Bombenaussicht". And nature pretty much gone, people complaining about more and more weird health problems and odd weather, and some even claiming that Earth vibes have altered. From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Path: biosci!agate!newsfeed.berkeley.edu!news-peer.gip.net!news.gsl.net!gip.net!portc01.blue.aol.com!audrey01.news.aol.com!not-for-mail From: jtyburczy@aol.com (JTyburczy) Newsgroups: bionet.neuroscience Subject: Re: Dyslexic Artist Astounds Theoreticians Lines: 20 NNTP-Posting-Host: ladder01.news.aol.com X-Admin: news@aol.com Date: 2 Feb 1999 01:50:22 GMT Organization: AOL http://www.aol.com References: <7951de$qs4$1@news.tamu.edu> Message-ID: <19990201205022.06436.00003161@ng14.aol.com> <> Not the truth. Your very first action was to file a complaint with AOL regarding my posting several harmless newsgroup pointers to a competely noncommercial site. Only after this did you attempt to contact me via "private" email. (Sort of a "shoot 'em in the back first, then ask questions later" method you got there, eh?) I truly hope nothing comes of your actions. If I hear ONE PEEP from AOL regarding your complaints about me, I will be forced to contact Texas A&M University regarding your continuing harassment of legitimate Internet users such as BIOSOUND and myself. JTyburczy From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 From: Brian Sandle Subject: Dental trouble & apnea (lidocaine abstracts) Newsgroups: alt.support.sleep-disorder,sci.med.dentistry,alt.support.chronic-pain,alt.med.fibromyalgia,bionet.neuroscience,alt.support.mult-sclerosis User-Agent: tin/pre-1.4-980226 (UNIX) (SunOS/5.4 (sun4m)) Organization: Southern Internet Services Message-ID: <917915890.461727@mnementh.southern.co.nz> Lines: 505 Date: Tue, 02 Feb 1999 00:38:12 GMT NNTP-Posting-Host: 202.37.188.6 X-Trace: news.clear.net.nz 917915892 202.37.188.6 (Tue, 02 Feb 1999 13:38:12 NZDT) NNTP-Posting-Date: Tue, 02 Feb 1999 13:38:12 NZDT Path: biosci!news.ic.sunysb.edu!news-nysernet-16.sprintlink.net!news.sprintlink.net!news-east1.sprintlink.net!news-peer1.sprintlink.net!-program!newsfeed.berkeley.edu!newsfeed.concentric.net!newsfeed.clear.net.nz!news.clear.net.nz!not-for-mail Apologies for a lengthy article. Perhaps more attention should be given to disturbance of the breathing stimulus mechanism in the sinus area. I have ben asking about licdocaine neurological effects on sci.med.dentistry and bionet.neuroscience. Now I wonder whether lidocaine may affect a person with a tendency to multiple sclerosis in the breathing centre, perhaps, then sleep apnea could set in and produce more nerological symptoms. Or the dental work might produce disturbance in the sinus which could reduce breathing stimulus. My left nostril gets a bit more blocked with pressure since an upper big molar root canal. Now it is 6 days since and I woke with a more blocked nostril than before. It has cleared a bit. I have been having some of the neurological troubles mentioned by stigmata1, but they have been clearing a bit since the root canal. The dentist found a fair bit of pus under the root dressing which had been in for a month. Brian Sandle *********************** Sleep Apnea Author: prepster Date: 1999/01/14 Forum: alt.support.sleep-disorder I have had Sleep Apnea for a while and only recently took action on it. My doctor says he wants to correct a deviated nasal septum, remove my tonsils and do an UPPP. I refuse to do the UPPP; it is painful with side effects and has a low success rate...comments? Would it also help to have my adenoids removed? ********************** Re: Chronic Pain Down Right since April Author: Barry Kaplan Date: 1998/12/22 Forums: alt.support.chronic-pain, alt.med.fibromyalgia more headers author posting history prev next _________________________________________________________________ Dave, What did they fill the root canal with? The most common root canal filling material is called "gutta percha" and it is fairly innocuous. In years past, two other materials were used. One is called "silver points". They are not good, but they shouldn't cause the pain you are reporting. They just corrode over time. The other material that is out of favor is called "sargenti paste" This stuff can be real bad news. I have heard of syptoms similar to yours, but not NEARLY as bad nor widespread in distribution. However, it is also possible that the thing causing the pain may not have been of dental origin. The distribution of the nerves in the mouth has nothing to do with the nerves in your arm and leg. If you reported the pain and tic only in your face, I might suspect things like trigeminal neuralgia (tic Douluoroeux). I know you said you saw 23 doctors, but there are two things you need to be certain to do (if you haven't already). First of all, I would make sure I had a second opinion onthe root canal by a board certified endodontist (root canal specialist) Secondly, you might consider seeing a neurologist about your other complaints. It is possible that the tooth you had the root canal done on may not have been the problem. I have never seen mouth pain refer farther than the sinuses or neck. You may have had a different problem to begin with. There are at least two physicians that often respond to posts an this newsgroup. Hopefully Mike, Todd ,and anyone else with anything to add will pipe up Barry (DDS) stigmata1@hotmail.com wrote in message <75p0a9$tug$1@nnrp1.dejanews.com>... >I hope there's an answer! In April of 1998 I went to get some routine dental >work done, and found that I required a root canal, which I assented to. >Almost immediately after the procedure, I started experiencing excrutiating >pain in that tooth, which seemed to inflame the entire right side of my face. >It was so bad I wanted to be knocked out and have it removed on site. >However, since I'm 23 all doctors advised me against removal and assured me >that within a month the pain would subside. Well, the pain became so bad >twice that I went to the emergency room because I couldn't take it, and they >gave me Percocet, Which I ended up being on for about two months. During this >time period, I started feeling a burning pain sensation "creeping" down my >arm and my leg, as well as the already established pain in my face, eye, >saggital plan, which led to a facial tic that I have to this day. But as this >pain started creeping down my extremities, I found it more and more difficult >to move my hand and my foot, writing was very difficult, I had trouble >holding the pen. Gradually, the excruciating pain gave way to a lesser pain, >and I was moved off of Percocet down to Hydrocodone, Then just OTC pain >relievers. I'm not lying prostrate in pain anymore, but I still have a >constant, low level pain that's down the right side of my body. When I sigh >or yawn or exhale deeply, I feel "bolts" of pain race down my right arm until >it 'hits' at the tips of the fingers. I also experience a phenomenon when I >hold my computer mouse, where my right hand will get 'cold shots' all over >the top of my hand when surrounding the mouse. There seem to be pain focal >points at the top of my spine and the bottom, and I feel the pain connected >and start to run down what feels like the center of my leg and arm where the >limb is subumerged in a burning sensation. Anyone know what this is, how it >came about, and the cure? > >Any answers appreciated, > >Dave Canova, >stigmata1@hotmail.com > ********************* Neurology 1992 Nov;42(11):2088-93 Lidocaine unmasks silent demyelinative lesions in multiple sclerosis. Sakurai M, Mannen T, Kanazawa I, Tanabe H Department of Neurology, School of Medicine, University of Tokyo, Japan. Blockage of a small number of sodium channels may prevent impulse conduction in some demyelinated segments of nerve fibers with low safety factors, thereby unmasking subclinical demyelinative lesions. On the basis of this hypothesis, lidocaine, a sodium channel blocker, was administered intravenously to 28 MS patients and to 19 normal subjects and seven patients with nondemyelinating diseases. As predicted, lidocaine (mean plasma level, 2.7 micrograms/ml) elicited reversible subclinical symptoms in 23 of the MS patients, but it had not effect on the control subjects. We made a quantitative study of the visual functions (visual acuity, color vision, visual evoked potential [VEP]) that were impaired in 15 MS patients. Of the 23 affected eyes, nine showed normal VEPs, indicative of the test's sensitivity to focal lesions. This test should be useful in the diagnosis of MS and in the evaluation of the subclinical activity of MS as well. PMID: 1331868, UI: 93063903 Masui 1998 May;47(5):570-5 [Midazolam for anesthetic induction in neonates]. [Article in Japanese] Kawakami K, Ohata J, Kadosaki M, Saito I, Iwasawa K, Mitono H Department of Anesthesiology, Nagano Children's Hospital. The purpose of this study is to evaluate the effects of midazolam on circulation, respiration, sedation, and liver function of the neonates. The study subjects are 27 neonates (body weight 2.1 to 3.8 kg, gestational age at birth 34 to 41 weeks) who underwent surgery in neonatal period. Of 27, 13 patients received lidocaine (1.5 mg.kg-1) immediately before tracheal intubation (group L), and 14 had midazolam (0.1 mg.kg-1) with lidocaine (group ML). We compared the effects of midazolam in the presence of lidocaine on the following parameters: (1) the incidence of hypotension (systolic blood pressure < 50 mmHg) and bradycardia (heart rate < 100 beats.min-1), (2) the incidence of apnea and desaturation of oxygen (< 80%), (3) the degree of sedation, and (4) the serum levels of bilirubin and unbound bilirubin after surgery. In group L, there were hypotension (1/13) and desaturation (1/13). In group ML, there were desaturation (1/14) and post-operative apnea (1/14). None in both groups developed bradycardia or intracranial hemorrhage. A single-dose of lidocaine induced sedation only in 4 neonates, while combination of midazolam and lidocaine in 11. None had elevation of either total or unbound bilirubin after surgery. In conclusion, the titrated dose of midazolam with lidocaine is useful for anesthetic induction of neonates, although cares should be taken on its adverse effects such as hypotension, desaturation, and post-operative apnea. Publication Types: * Clinical trial PMID: 9621667, UI: 98284687 _________________ Anesthesiology 1998 Mar;88(3):761-7 Hypoxia causes apnea during epidural anesthesia in rabbits. Hogan QH, Amuzu J, Clifford PS, Bosnjak ZJ, Kampine JP Department of Anesthesiology, Medical College of Wisconsin and the Zablocki Veterans Administration Medical Center, Milwaukee 53226, USA. BACKGROUND: Although pulmonary function is minimally changed by neuraxial blockade in most cases, ventilatory arrest may ensue in rare cases. The authors examined the mechanism of apnea in a rabbit model of sudden ventilatory arrest during the combination of epidural anesthesia and hypoxia. METHODS: Rabbits were studied during alpha-chloralose sedation and spontaneous ventilation through a tracheostomy tube. Heart rate and mean arterial pressure were monitored by intraarterial cannulation. Respiratory rate and tidal volume were measured by pneumotachograph. Responses were recorded during administration of oxygen at inspired oxygen concentrations of 11% for 2.5 min and 0% for 40 s, before and after either thoracolumbar epidural blockade (0.4 ml/kg lidocaine, 1.5%) or intramuscular lidocaine (15 mg/kg). In a third group of animals, epinephrine was given intravenously during epidural blockade to return mean arterial pressure to baseline values before hypoxia. In a fourth group of animals, which did not get lidocaine, sympathetic blockade and hypotension were produced with intravenously administered trimethaphan rather than epidural blockade. RESULTS: Thoracolumbar epidural anesthesia decreased mean arterial pressure from 76 +/- 4 mmHg (mean +/- SE) to 42 +/- 2 mmHg. Apnea during hypoxia occurred in 90% of these animals (nine of ten) but in only 11% of animals (one of nine) after intramuscularly administered lidocaine (P < 0.01). Treatment of epidural hypotension with epinephrine prevented apnea (zero of nine animals). Apnea during hypoxia occurred in 50% (three of six) of animals given trimethaphan. Apnea in all groups was sudden in onset, with no preceding decreases in respiratory rate or tidal volume. CONCLUSIONS: Epidural anesthesia results in a narrowed margin of safety for oxygen delivery to the brain and predisposes subjects to ventilatory arrest during hypoxia. This results from the combined effects of decreased blood oxygen content, which is due to decreased inspired oxygen concentration superimposed on circulatory depression due to neural blockade. PMID: 9523821, UI: 98181995 Am J Respir Crit Care Med 1995 Jun;151(6):1857-61 Effect of upper airway anesthesia on obstructive sleep apnea. Berry RB, Kouchi KG, Bower JL, Light RW Department of Medicine, Long Beach VA Medical Center, CA 90822, USA. We hypothesized that upper airway mechanoreceptors contribute to the arousal stimulus that occurs with upper airway occlusion in obstructive sleep apnea (OSA). If so, upper airway anesthesia (UAA) should reduce the arousal stimulus and impair the arousal response. To test this hypothesis, we studied the effects of UAA on apnea duration and the esophageal pressure deflection before arousal in a group of patients with severe OSA. On two study nights separated by one week, subjects were monitored for 2 h after lights out. They were then awakened and either 5 cc of 4% lidocaine or saline (random order) was dripped into the upper airway via the nose over 10 min. Another 2 h of monitoring was then performed. Variables on the first and second parts of the control (C1 and C2) and lidocaine nights (L1 and L2) were compared during non-rapid eye movement sleep using the analysis of variance. With lidocaine, the mean (+/- SEM) apnea duration increased from 24.2 +/- 2.6 (L1) to 30.7 +/- 2.3 (L2) s but with saline the apnea length was unchanged from 23.3 +/- 1.5 (C1) to 23.4 +/- 1.6 (C2) (L2 > [L1, C1, C2], p < 0.01). In addition, the maximum esophageal pressure deflection (cm H2O) before arousal increased after lidocaine from 63.6 +/- 14.5 (L1) to 84.1 +/- 14.7 (L2) but after saline was unchanged from 62.1 +/- 15.4 (C1) to 60.0 +/- 15.2 (C2), (L2 > [L1, C1, C2], p < 0.05). We conclude that UAA impairs the arousal response to airway occlusion. This suggests that input from upper airway mechanoreceptors during obstructive events contributes to the total arousal stimulus in patients with OSA. Publication Types: * Clinical trial * Randomized controlled trial PMID: 7767531, UI: 95285040 _____________________________________________________ Am J Respir Crit Care Med 1995 Apr;151(4):1108-12 Topical oropharyngeal anesthesia in patients with obstructive sleep apnea. Deegan PC, Mulloy E, McNicholas WT Department of Respiratory Medicine, University College, Dublin, Ireland. Topical oropharyngeal anesthesia (TOPA) increases obstructive sleep apnea (OSA) frequency in both normal subjects and loud snorers. The effects of TOPA in established OSA were assessed in six male patients with a mean age (+/- SEM) of 50 +/- 5.3 yr. Following an acclimatization night, each subject underwent two overnight sleep studies, randomly assigned to TOPA (10% lidocaine spray and 0.25% bupivocaine gargle) and control (C) (saline placebo). Patients demonstrated sleep efficiencies of 93 +/- 2.9% (mean +/- SEM) during C and 88 +/- 2.9% during TOPA. Overall apnea-hypopnea (AH) frequency, using inductance plethysmography, showed little change: 21.2 +/- 3.6 on C versus 25.1 +/- 3.5 events/h on TOPA nights (p = 0.12). There was no significant increase in AH duration with TOPA, and oxygen desaturation (> or = 4%) frequency was similar: 21.1 +/- 3.9 per hour during TOPA versus 23.6 +/- 5.9 during C. However, obstructive AHs showed a change in thoracoabdominal motion from C to TOPA nights, with an increase in events with abdominal paradox from 3.1 +/- 1.1 to 10.3 +/- 3.1 per hour (p = 0.03), and a reduction in events with ribcage paradox from 13.1 +/- 1.6 to 8.2 +/- 2.4 per hour (p = 0.08). Central and mixed AHs demonstrated similar frequencies on both nights. These data support an impairment of upper airway (UA) protective reflexes among patients with OSA. Publication Types: * Clinical trial * Randomized controlled trial PMID: 7697239, UI: 95211324 Brain Res 1991 Sep 27;560(1-2):321-5 Trigeminal mediation of the diving response in the muskrat. Panneton WM Department of Anatomy and Neurobiology, St. Louis School of Medicine, MO 63104. Stimulation of the nasal cavity elicits powerful cardiorespiratory responses similar to the diving response. In the present study, bradycardia and apnea were elicited in muskrats by stimulation of the nasal cavity with ammonia vapors. These responses could be blocked by injections of 2% lidocaine made bilaterally into the medullary dorsal horns of the trigeminal sensory complex. However, the bradycardia due to activation of the baroreceptor reflex with intravenous phenylephrine was retained. These data implicate trigeminal neurons in the medullary dorsal horn as modulators of autonomic activity, especially in the cardiorespiratory adjustments after nasal stimulation. PMID: 1760738, UI: 92103521 ________________________________________________________________ Other Formats: [Citation Format] [MEDLINE Format] Links: [114 medline neighbors] Am Rev Respir Dis 1991 Apr;143(4 Pt 1):810-3 Obstructive sleep apnea following topical oropharyngeal anesthesia in loud snorers. Chadwick GA, Crowley P, Fitzgerald MX, O'Regan RG, McNicholas WT Department of Respiratory Medicine, University College, Dublin, Ireland. Previous studies support the presence of an upper airway reflex mechanism that contributes to the maintenance of upper airway patency during sleep. We investigated the possibility that interference with this reflex mechanism contributes to the development of obstructive sleep apnea. Eight otherwise asymptomatic snorers (seven male and one female), age 39 +/- 5.3 yr (mean +/- SEM), underwent overnight sleep studies on three successive nights. An acclimatization night was followed by two study nights randomly assigned to control (C) and oropharyngeal anesthesia (OPA). On the OPA night topical anesthesia was induced using 10% lidocaine spray and 0.25% bupivacaine gargle. A saline placebo was used on night C. All subjects slept well on both study nights (mean sleep duration was 6.2 h on both study nights), and sleep stage distribution was similar on both nights. Obstructive apneas and hypopneas (OAH) rose from 114 +/- 43 during C to 170 +/- 49 during OPA (p less than 0.02). Central apneas and hypopneas (CAH) were unchanged between the two nights (8 +/- 4.9 versus 7 +/- 3). The duration of OAH was similar on both study nights (20 +/- 1.9 s during C versus 20 +/- 1.5 s during OPA). The frequency of movement arousals terminating OAH tended to be higher during OPA (7 +/- 2.9/h) than during C (3 +/- 0.7); P = NS. The frequency of oxyhemoglobin desaturations was also higher during OPA (5 +/- 2.1/h) than during C (3 +/- 1.4), p less than 0.07. PMID: 2008992, UI: 91181783 ________________________________________________________________ Other Formats: [Citation Format] [MEDLINE Format] Links: [109 medline neighbors] Am Rev Respir Dis 1985 Nov;132(5):972-5 The effects of nasal anesthesia on breathing during sleep. White DP, Cadieux RJ, Lombard RM, Bixler EO, Kales A, Zwillich CW Inability to breathe through the nose is an increasingly recognized cause of disordered breathing during sleep. To test the hypothesis that this respiratory dysrhythmia could result from loss of neuronal input to respiration from receptors located in the nose, we anesthetized the nasal passages of 10 normal men during sleep. Each subject spent 4 consecutive nights in the sleep laboratory while sleep stages, breathing patterns, respiratory effort, and arterial oxygen saturation were monitored. Night 1 was for acclimatization with Nights 3 and 4 being randomized to nasal spraying with either 4% lidocaine or placebo. On the lidocaine and placebo nights (Nights 3 and 4) the nasal passages were also sprayed with a decongestant to prevent increased nasal air-flow resistance resulting from mucosal swelling. To control for the possible effects of this decongestant, an additional night (Night 2) was included during which the nasal passages were sprayed with room air. Parallel studies conducted during wakefulness demonstrated low nasal resistance during the lidocaine-decongestant regimen. Because of the short duration of anesthesia with lidocaine, spraying was done at lights out and 2.5 and 5 h later. On the placebo night (decongestant plus saline) there were 6.4 +/- 1.8 (SEM) disordered breathing events (apneas plus hypopneas) per subject, whereas with lidocaine (plus decongestant) this increased fourfold to 25.8 +/- 7.8 events per subject (p less than 0.05). The majority of the disordered breathing events were apneas and were fairly evenly distributed between central and obstructive events. The magnitude of these changes is similar to that previously reported with complete nasal obstruction. These results suggest that nasal receptors sensitive to air flow may be important in maintaining breathing rhythmicity during sleep. Publication Types: * Clinical trial * Randomized controlled trial PMID: 4062052, UI: 86048887 this document Am J Perinatol 1987 Apr;4(2):164-6 Lidocaine toxicity after maternal pudendal anesthesia in a term infant with fetal distress. Bozynski ME, Rubarth LB, Patel JA There have been many reports of lidocaine toxicity especially after maternal paracervical block anesthesia. We recently treated a term infant with evidence of fetal distress who presented with symptoms of lidocaine toxicity after maternal pudendal anesthesia. The infant developed apnea and bradycardia soon after birth which responded to mechanical ventilation and epinephrine. A prolonged Q-T interval was noted on day 1 which normalized by day 3. Cord blood was assayed and revealed an elevated lidocaine level. Lidocaine toxicity has been associated with fetal distress secondary to fetal ion trapping in the presence of acidosis. Although good response to supportive therapy occurred in our patient, other methods of therapy such as exchange transfusion and treatment of seizures may be required in some cases. Awareness of this now uncommon syndrome will lead to prompt diagnosis, appropriate work-up, and management. PMID: 3566884, UI: 87184830 ________________________________________________________________ Other Formats: [Citation Format] [MEDLINE Format] Links: [169 medline neighbors] Am J Physiol 1977 Jul;233(1):R30-6 Properties of the laryngeal chemoreflex in neonatal piglets. Lee JC, Stoll BJ, Downing SE Cardiorespiratory reflex responses to laryngeal chemoreceptor stimulation were studied in 62 piglets of both sexes varying in age from 1 to 79 days. The distal trachea was cannulated to provide a free airway and the proximal end used to introduce fluids into the laryngeal area. Introduction of either water or milk produced apnea, bradycardia, and hypertension. Swab application of test fluids to the laryngeal epithelium produced similar responses. The reflex could be interrupted by flushing the laryngeal region with saline, by cutting the superior laryngeal nerves (SLN) or by anesthetizing the laryngeal epithelium with lidocaine. Electrical stimulation of SLN elicited identical responses. Respiratory inhibition by the reflex was enhanced following central depression with chloralose and overridden by administration of the respiratory stimulant, aminophylline. The relative potency of the laryngeal reflex was estimated to be equivalent to about 40% of the dose of chloralose which produced permanent respiratory arrest. It is concluded that in circumstances where respiratory drive is reduced the laryngeal inhibitory reflex is capable of caused persistent apnea and asphyxial death in the young piglet. PMID: 18025, UI: 77219523 ________________________________________________________________ Other Formats: [Citation Format] [MEDLINE Format] Links: [102 medline neighbors] Rev Bras Pesqui Med Biol 1976 Dec;9(5-6):229-37 Lethal effect of the serotonin-xylocaineR association in ganglion-blocked rats. Valle LB, Oliveira-Filho RM, Armonia PL, Saraceni G Jr, Nassif M, De Lucia R In rats anestetized with urethane and under ganglionic blockade by hexamethonium (20 mg/kg, i.v.), the i.v. injection of serotonin (60 mug/kg) determined apnea, ECG alterations and a brief hypotensive response which is similar to that as elicited when 5-HT is given to intact rats. During the hypertension which follows that initial response, apnea is still present along with more severe ECG changes. After that, blood pressure falls into a prolonged hypotension, which is invariably accompanied by death. Neither norepinephrine, nor respiratory analeptics (CoramineR, RemeflinF) were able to prevent the fatal outcome. Only artificial respiration was found to be useful in some instances. It was concluded that the association serotonin plus lidocaine becomes lethal when given to ganglion-blocked rate, and this toxic effect can be ascribed mainly to the respiratory depressor activity of the drugs. PMID: 1013401, UI: 77103742 ___________________________ Z Orthop Ihre Grenzgeb 1974 Oct;112(5):1053-62 From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Path: biosci!news.stanford.edu!logbridge.uoregon.edu!sunqbc.risq.qc.ca!newspeer.monmouth.com!newsfeed.xcom.net!cam-news-hub1.bbnplanet.com!nyc-news-feed1.bbnplanet.com!news.gtei.net!news.udel.edu!not-for-mail From: who@cares.com (justus) Newsgroups: bionet.neuroscience Subject: Re: Dolphin brain, language, and intelligence Date: Tue, 02 Feb 1999 15:42:28 GMT Organization: University of Delaware Lines: 26 Message-ID: <36b71c96.259162896@news.udel.edu> References: <19990123184419.27486.00001075@ngol03.aol.com> <36B6E488.3655@medphys.ucl.ac.uk> NNTP-Posting-Host: justus.psych.udel.edu X-Newsreader: Forte Free Agent 1.11/32.235 So lets put in another possibel semantic confound: how about the different apparen abilities between organisms within and between species to abtsract? Justus > >This means that it is no good to say "having a language" is intelligent. >Micro-organisms don't need vocal language because they have better. >Language is prone to misinterpretation while chemical and electrical >signals (in some sense ...) are not. > >Ivo > > > >-- >Ivo Kwee, >Department of Medical Physics and Bioengineering, >University College London. > >Office: 0171 - 209 6415 Fax: 0171 - 209 6269 >Home: 0171 - 794 5243 E-mail: kwee@medphys.ucl.ac.uk > From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 From: "Guenther And Rocio Schweigl" Subject: Nicholas Update Date: Tue, 2 Feb 1999 09:43:00 -0500 Lines: 35 X-Newsreader: Microsoft Outlook Express 4.72.3155.0 X-MimeOLE: Produced By Microsoft MimeOLE V4.72.3155.0 Message-ID: Newsgroups: bionet.neuroscience NNTP-Posting-Host: d138-xa101h1-toro-pdi.attcanada.net [142.194.190.138] Path: biosci!news.stanford.edu!su-news-feed2.bbnplanet.com!su-news-hub1.bbnplanet.com!news.gtei.net!nntp.flash.net!newsswitch.lcs.mit.edu!newsfeed.cwix.com!207.68.152.14!upnetnews04!upnetnews05 Nicholas (Born Sept 13, 98) was diagnosed with Stage 3 brain damage after birth due to problems in the womb. At the onset, we as parents turned to this N/G to find some anwers (and thank you to those that did provide them as best as you could) Currently, Nicholas (4-1/2 months old) is doing very well (actual, about 1 to 2 months ahead of milestones set for normal babies). He's happy, alert, vocalizing and active with no signs on any problems so much so that he has impressed the the doctors that did the initial diagnosis. We can only hope that this remains this way (knock on wood). Our approach , for those that may have similar problems. 1. Lot's of love. 2. If you believe and feel that they have no handicap and that the what ever the outcome is normal and not a problem (so will your child) and it will fail to become a problem that can't be dealed with. 3. Learn everything that you can (read, ask, question). 4. Enjoy yourself with your child and play games which help in active learning. 5. Be consistant and ensure that everyone that is in contact with him follows the objects that you set forth. 6. Hope your luck and no problems develop. 7. Pray. Pray Lots! (It doesn't hurt). It pays to stack the deck in your favour for the best outcome. Regards, Guenther Schweigl (Thanks F.F. LeFever for all of the information that you provided). From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Path: biosci!news.stanford.edu!newsfeed.concentric.net!newspeer1.nac.net!news.maxwell.syr.edu!news-peer.gip.net!news.gsl.net!gip.net!portc01.blue.aol.com!audrey01.news.aol.com!not-for-mail From: jtyburczy@aol.com (JTyburczy) Newsgroups: bionet.neuroscience Subject: Re: Dyslexic Artist Astounds Theoreticians Lines: 5 NNTP-Posting-Host: ladder01.news.aol.com X-Admin: news@aol.com Date: 2 Feb 1999 23:38:49 GMT Organization: AOL http://www.aol.com References: <796cc4$162$1@news.tamu.edu> Message-ID: <19990202183849.27832.00003580@ng112.aol.com> If all parties are satisfied, I then herebey close this discussion with an invitation for all to visit the neuroscientifically-relevant images posted at... http://members.aol.com/jrubu/noyes.htm From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Path: biosci!news.stanford.edu!newsfeed.berkeley.edu!awabi.library.ucla.edu!164.67.43.25!news.ucla.edu!not-for-mail From: cheney@ucla.edu (mike cheney) Newsgroups: bionet.neuroscience Subject: Re: Dolphin brain Date: Tue, 02 Feb 1999 23:28:47 GMT Organization: University of California, Los Angeles Lines: 24 Message-ID: <36b789e6.100696801@news.ucla.edu> References: <19990123093149.19507.00000817@ngol01.aol.com> <78v6h5$gfa$1@news0.skynet.be> Reply-To: cheney@ucla.edu NNTP-Posting-Host: 149.142.108.65 X-Newsreader: Forte Free Agent 1.11/32.235 On Sat, 30 Jan 1999 16:01:16 +0100, "dominique.flahaut" wrote: > > >>In article <19990123093149.19507.00000817@ngol01.aol.com>, >>tonyjeffs2@aol.comTonyJ (TonyJeffs2) wrote: >> >>| Dolphins have biger brains than people. I always thought maybe it is a >bigger >>| cerebellum or something to do with movement, but I recently heared that >they >>| have a bigger cerebral cortex, so now I'm intrigued. > > >I've also heared that dolphins have bigger frontal and prefrontal areas. But >I have no any objective or sure information about that. If that was actually >confirmed, I would be profoundly intrigued too... In humans, at least, there is no correlation between brain size and intellegence, so I don't know how much you could infer from the size of the dolphin brains... -mike From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 From: jenrun@newsguy.com (Rauni) Newsgroups: alt.support.sleep-disorder,sci.med.dentistry,alt.support.chronic-pain,alt.med.fibromyalgia,bionet.neuroscience,alt.support.mult-sclerosis Subject: Re: Dental trouble & apnea (lidocaine abstracts) Date: Tue, 02 Feb 1999 21:56:13 GMT Organization: http://extra.newsguy.com Lines: 514 Message-ID: <36c4737b.12725485@207.211.168.90> References: <917915890.461727@mnementh.southern.co.nz> Reply-To: jenrun@newsguy.com NNTP-Posting-Host: p-943.newsdawg.com Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Newsreader: Forte Agent 1.5/32.451 X-No-Archive: yes Path: biosci!news.ic.sunysb.edu!news-nysernet-16.sprintlink.net!news-in-east1.sprintlink.net!news.sprintlink.net!news-peer1.sprintlink.net!-program!newsfeed.berkeley.edu!pln-w!spln!extra.newsguy.com!newsp.newsguy.com!enews1 I have has seizures after shots of lidocaine. I don't know if that is common or not. Makes going to the dentist difficult. I need a melogram and can't get one because of my reaction to lidocaine. BTW I also have a seizure disorder On Tue, 02 Feb 1999 00:38:12 GMT, Brian Sandle wrote: >Apologies for a lengthy article. Perhaps more attention should be given >to disturbance of the breathing stimulus mechanism in the sinus area. > >I have ben asking about licdocaine neurological effects on >sci.med.dentistry and bionet.neuroscience. > >Now I wonder whether lidocaine may affect a person with a tendency to >multiple sclerosis in the breathing centre, perhaps, then sleep apnea >could set in and produce more nerological symptoms. > >Or the dental work might produce disturbance in the sinus which could >reduce breathing stimulus. > >My left nostril gets a bit more blocked with pressure since an upper big >molar root canal. Now it is 6 days since and I woke with a more blocked >nostril than before. It has cleared a bit. > >I have been having some of the neurological troubles mentioned by >stigmata1, but they have been clearing a bit since the root canal. The >dentist found a fair bit of pus under the root dressing which had been in >for a month. > >Brian Sandle > > *********************** > Sleep Apnea > Author: prepster > Date: 1999/01/14 > Forum: alt.support.sleep-disorder > >I have had Sleep Apnea for a while and only recently took action on it. My >doctor says he wants to correct a deviated nasal septum, remove my tonsils >and do an UPPP. > >I refuse to do the UPPP; it is painful with side effects and has a low >success rate...comments? Would it also help to have my adenoids removed? >********************** > > Re: Chronic Pain Down Right since April > Author: Barry Kaplan > Date: 1998/12/22 > Forums: alt.support.chronic-pain, alt.med.fibromyalgia > more headers author posting history prev next > _________________________________________________________________ > >Dave, >What did they fill the root canal with? >The most common root canal filling material is called "gutta percha" and it >is fairly innocuous. >In years past, two other materials were used. One is called "silver >points". They are not good, but they shouldn't cause the pain you are >reporting. They just corrode over time. >The other material that is out of favor is called "sargenti paste" This >stuff can be real bad news. I have heard of syptoms similar to yours, but >not NEARLY as bad nor widespread in distribution. >However, it is also possible that the thing causing the pain may not have >been of dental origin. The distribution of the nerves in the mouth has >nothing to do with the nerves in your arm and leg. If you reported the pain >and tic only in your face, I might suspect things like trigeminal neuralgia >(tic Douluoroeux). >I know you said you saw 23 doctors, but there are two things you need to be >certain to do (if you haven't already). First of all, I would make sure I >had a second opinion onthe root canal by a board certified endodontist (root >canal specialist) >Secondly, you might consider seeing a neurologist about your other >complaints. >It is possible that the tooth you had the root canal done on may not have >been the problem. I have never seen mouth pain refer farther than the >sinuses or neck. You may have had a different problem to begin with. > >There are at least two physicians that often respond to posts an this >newsgroup. Hopefully Mike, Todd ,and anyone else with anything to add will >pipe up > >Barry (DDS) > > > >stigmata1@hotmail.com wrote in message <75p0a9$tug$1@nnrp1.dejanews.com>... >>I hope there's an answer! In April of 1998 I went to get some routine >dental >>work done, and found that I required a root canal, which I assented to. >>Almost immediately after the procedure, I started experiencing excrutiating >>pain in that tooth, which seemed to inflame the entire right side of my >face. >>It was so bad I wanted to be knocked out and have it removed on site. >>However, since I'm 23 all doctors advised me against removal and assured me >>that within a month the pain would subside. Well, the pain became so bad >>twice that I went to the emergency room because I couldn't take it, and >they >>gave me Percocet, Which I ended up being on for about two months. During >this >>time period, I started feeling a burning pain sensation "creeping" down my >>arm and my leg, as well as the already established pain in my face, eye, >>saggital plan, which led to a facial tic that I have to this day. But as >this >>pain started creeping down my extremities, I found it more and more >difficult >>to move my hand and my foot, writing was very difficult, I had trouble >>holding the pen. Gradually, the excruciating pain gave way to a lesser >pain, >>and I was moved off of Percocet down to Hydrocodone, Then just OTC pain >>relievers. I'm not lying prostrate in pain anymore, but I still have a >>constant, low level pain that's down the right side of my body. When I sigh >>or yawn or exhale deeply, I feel "bolts" of pain race down my right arm >until >>it 'hits' at the tips of the fingers. I also experience a phenomenon >when I >>hold my computer mouse, where my right hand will get 'cold shots' all over >>the top of my hand when surrounding the mouse. There seem to be pain focal >>points at the top of my spine and the bottom, and I feel the pain connected >>and start to run down what feels like the center of my leg and arm where >the >>limb is subumerged in a burning sensation. Anyone know what this is, how it >>came about, and the cure? >> >>Any answers appreciated, >> >>Dave Canova, >>stigmata1@hotmail.com >> >********************* > > Neurology 1992 Nov;42(11):2088-93 > >Lidocaine unmasks silent demyelinative lesions in multiple sclerosis. > > Sakurai M, Mannen T, Kanazawa I, Tanabe H > > Department of Neurology, School of Medicine, University of Tokyo, > Japan. > > Blockage of a small number of sodium channels may prevent impulse > conduction in some demyelinated segments of nerve fibers with low > safety factors, thereby unmasking subclinical demyelinative lesions. > On the basis of this hypothesis, lidocaine, a sodium channel blocker, > was administered intravenously to 28 MS patients and to 19 normal > subjects and seven patients with nondemyelinating diseases. As > predicted, lidocaine (mean plasma level, 2.7 micrograms/ml) elicited > reversible subclinical symptoms in 23 of the MS patients, but it had > not effect on the control subjects. We made a quantitative study of > the visual functions (visual acuity, color vision, visual evoked > potential [VEP]) that were impaired in 15 MS patients. Of the 23 > affected eyes, nine showed normal VEPs, indicative of the test's > sensitivity to focal lesions. This test should be useful in the > diagnosis of MS and in the evaluation of the subclinical activity of > MS as well. > > PMID: 1331868, UI: 93063903 > Masui 1998 May;47(5):570-5 > >[Midazolam for anesthetic induction in neonates]. > > [Article in Japanese] > > Kawakami K, Ohata J, Kadosaki M, Saito I, Iwasawa K, Mitono H > > Department of Anesthesiology, Nagano Children's Hospital. > > The purpose of this study is to evaluate the effects of midazolam on > circulation, respiration, sedation, and liver function of the > neonates. The study subjects are 27 neonates (body weight 2.1 to 3.8 > kg, gestational age at birth 34 to 41 weeks) who underwent surgery in > neonatal period. Of 27, 13 patients received lidocaine (1.5 mg.kg-1) > immediately before tracheal intubation (group L), and 14 had > midazolam (0.1 mg.kg-1) with lidocaine (group ML). We compared the > effects of midazolam in the presence of lidocaine on the following > parameters: (1) the incidence of hypotension (systolic blood pressure > < 50 mmHg) and bradycardia (heart rate < 100 beats.min-1), (2) the > incidence of apnea and desaturation of oxygen (< 80%), (3) the degree > of sedation, and (4) the serum levels of bilirubin and unbound > bilirubin after surgery. In group L, there were hypotension (1/13) > and desaturation (1/13). In group ML, there were desaturation (1/14) > and post-operative apnea (1/14). None in both groups developed > bradycardia or intracranial hemorrhage. A single-dose of lidocaine > induced sedation only in 4 neonates, while combination of midazolam > and lidocaine in 11. None had elevation of either total or unbound > bilirubin after surgery. In conclusion, the titrated dose of > midazolam with lidocaine is useful for anesthetic induction of > neonates, although cares should be taken on its adverse effects such > as hypotension, desaturation, and post-operative apnea. > > Publication Types: > * Clinical trial > > PMID: 9621667, UI: 98284687 > _________________ > > Anesthesiology 1998 Mar;88(3):761-7 > >Hypoxia causes apnea during epidural anesthesia in rabbits. > > Hogan QH, Amuzu J, Clifford PS, Bosnjak ZJ, Kampine JP > > Department of Anesthesiology, Medical College of Wisconsin and the > Zablocki Veterans Administration Medical Center, Milwaukee 53226, > USA. > > BACKGROUND: Although pulmonary function is minimally changed by > neuraxial blockade in most cases, ventilatory arrest may ensue in > rare cases. The authors examined the mechanism of apnea in a rabbit > model of sudden ventilatory arrest during the combination of epidural > anesthesia and hypoxia. METHODS: Rabbits were studied during > alpha-chloralose sedation and spontaneous ventilation through a > tracheostomy tube. Heart rate and mean arterial pressure were > monitored by intraarterial cannulation. Respiratory rate and tidal > volume were measured by pneumotachograph. Responses were recorded > during administration of oxygen at inspired oxygen concentrations of > 11% for 2.5 min and 0% for 40 s, before and after either > thoracolumbar epidural blockade (0.4 ml/kg lidocaine, 1.5%) or > intramuscular lidocaine (15 mg/kg). In a third group of animals, > epinephrine was given intravenously during epidural blockade to > return mean arterial pressure to baseline values before hypoxia. In a > fourth group of animals, which did not get lidocaine, sympathetic > blockade and hypotension were produced with intravenously > administered trimethaphan rather than epidural blockade. RESULTS: > Thoracolumbar epidural anesthesia decreased mean arterial pressure > from 76 +/- 4 mmHg (mean +/- SE) to 42 +/- 2 mmHg. Apnea during > hypoxia occurred in 90% of these animals (nine of ten) but in only > 11% of animals (one of nine) after intramuscularly administered > lidocaine (P < 0.01). Treatment of epidural hypotension with > epinephrine prevented apnea (zero of nine animals). Apnea during > hypoxia occurred in 50% (three of six) of animals given trimethaphan. > Apnea in all groups was sudden in onset, with no preceding decreases > in respiratory rate or tidal volume. CONCLUSIONS: Epidural anesthesia > results in a narrowed margin of safety for oxygen delivery to the > brain and predisposes subjects to ventilatory arrest during hypoxia. > This results from the combined effects of decreased blood oxygen > content, which is due to decreased inspired oxygen concentration > superimposed on circulatory depression due to neural blockade. > > PMID: 9523821, UI: 98181995 > > Am J Respir Crit Care Med 1995 Jun;151(6):1857-61 > >Effect of upper airway anesthesia on obstructive sleep apnea. > > Berry RB, Kouchi KG, Bower JL, Light RW > > Department of Medicine, Long Beach VA Medical Center, CA 90822, USA. > > We hypothesized that upper airway mechanoreceptors contribute to the > arousal stimulus that occurs with upper airway occlusion in > obstructive sleep apnea (OSA). If so, upper airway anesthesia (UAA) > should reduce the arousal stimulus and impair the arousal response. > To test this hypothesis, we studied the effects of UAA on apnea > duration and the esophageal pressure deflection before arousal in a > group of patients with severe OSA. On two study nights separated by > one week, subjects were monitored for 2 h after lights out. They were > then awakened and either 5 cc of 4% lidocaine or saline (random > order) was dripped into the upper airway via the nose over 10 min. > Another 2 h of monitoring was then performed. Variables on the first > and second parts of the control (C1 and C2) and lidocaine nights (L1 > and L2) were compared during non-rapid eye movement sleep using the > analysis of variance. With lidocaine, the mean (+/- SEM) apnea > duration increased from 24.2 +/- 2.6 (L1) to 30.7 +/- 2.3 (L2) s but > with saline the apnea length was unchanged from 23.3 +/- 1.5 (C1) to > 23.4 +/- 1.6 (C2) (L2 > [L1, C1, C2], p < 0.01). In addition, the > maximum esophageal pressure deflection (cm H2O) before arousal > increased after lidocaine from 63.6 +/- 14.5 (L1) to 84.1 +/- 14.7 > (L2) but after saline was unchanged from 62.1 +/- 15.4 (C1) to 60.0 > +/- 15.2 (C2), (L2 > [L1, C1, C2], p < 0.05). We conclude that UAA > impairs the arousal response to airway occlusion. This suggests that > input from upper airway mechanoreceptors during obstructive events > contributes to the total arousal stimulus in patients with OSA. > > Publication Types: > * Clinical trial > * Randomized controlled trial > > PMID: 7767531, UI: 95285040 > _____________________________________________________ > > Am J Respir Crit Care Med 1995 Apr;151(4):1108-12 > >Topical oropharyngeal anesthesia in patients with obstructive sleep apnea. > > Deegan PC, Mulloy E, McNicholas WT > > Department of Respiratory Medicine, University College, Dublin, > Ireland. > > Topical oropharyngeal anesthesia (TOPA) increases obstructive sleep > apnea (OSA) frequency in both normal subjects and loud snorers. The > effects of TOPA in established OSA were assessed in six male patients > with a mean age (+/- SEM) of 50 +/- 5.3 yr. Following an > acclimatization night, each subject underwent two overnight sleep > studies, randomly assigned to TOPA (10% lidocaine spray and 0.25% > bupivocaine gargle) and control (C) (saline placebo). Patients > demonstrated sleep efficiencies of 93 +/- 2.9% (mean +/- SEM) during > C and 88 +/- 2.9% during TOPA. Overall apnea-hypopnea (AH) frequency, > using inductance plethysmography, showed little change: 21.2 +/- 3.6 > on C versus 25.1 +/- 3.5 events/h on TOPA nights (p = 0.12). There > was no significant increase in AH duration with TOPA, and oxygen > desaturation (> or = 4%) frequency was similar: 21.1 +/- 3.9 per hour > during TOPA versus 23.6 +/- 5.9 during C. However, obstructive AHs > showed a change in thoracoabdominal motion from C to TOPA nights, > with an increase in events with abdominal paradox from 3.1 +/- 1.1 to > 10.3 +/- 3.1 per hour (p = 0.03), and a reduction in events with > ribcage paradox from 13.1 +/- 1.6 to 8.2 +/- 2.4 per hour (p = 0.08). > Central and mixed AHs demonstrated similar frequencies on both > nights. These data support an impairment of upper airway (UA) > protective reflexes among patients with OSA. > > Publication Types: > * Clinical trial > * Randomized controlled trial > > PMID: 7697239, UI: 95211324 > > > Brain Res 1991 Sep 27;560(1-2):321-5 > >Trigeminal mediation of the diving response in the muskrat. > > Panneton WM > > Department of Anatomy and Neurobiology, St. Louis School of Medicine, > MO 63104. > > Stimulation of the nasal cavity elicits powerful cardiorespiratory > responses similar to the diving response. In the present study, > bradycardia and apnea were elicited in muskrats by stimulation of the > nasal cavity with ammonia vapors. These responses could be blocked by > injections of 2% lidocaine made bilaterally into the medullary dorsal > horns of the trigeminal sensory complex. However, the bradycardia due > to activation of the baroreceptor reflex with intravenous > phenylephrine was retained. These data implicate trigeminal neurons > in the medullary dorsal horn as modulators of autonomic activity, > especially in the cardiorespiratory adjustments after nasal > stimulation. > > PMID: 1760738, UI: 92103521 > ________________________________________________________________ > > Other Formats: [Citation Format] [MEDLINE Format] > Links: [114 medline neighbors] > > Am Rev Respir Dis 1991 Apr;143(4 Pt 1):810-3 > >Obstructive sleep apnea following topical oropharyngeal anesthesia in loud >snorers. > > Chadwick GA, Crowley P, Fitzgerald MX, O'Regan RG, McNicholas WT > > Department of Respiratory Medicine, University College, Dublin, > Ireland. > > Previous studies support the presence of an upper airway reflex > mechanism that contributes to the maintenance of upper airway patency > during sleep. We investigated the possibility that interference with > this reflex mechanism contributes to the development of obstructive > sleep apnea. Eight otherwise asymptomatic snorers (seven male and one > female), age 39 +/- 5.3 yr (mean +/- SEM), underwent overnight sleep > studies on three successive nights. An acclimatization night was > followed by two study nights randomly assigned to control (C) and > oropharyngeal anesthesia (OPA). On the OPA night topical anesthesia > was induced using 10% lidocaine spray and 0.25% bupivacaine gargle. A > saline placebo was used on night C. All subjects slept well on both > study nights (mean sleep duration was 6.2 h on both study nights), > and sleep stage distribution was similar on both nights. Obstructive > apneas and hypopneas (OAH) rose from 114 +/- 43 during C to 170 +/- > 49 during OPA (p less than 0.02). Central apneas and hypopneas (CAH) > were unchanged between the two nights (8 +/- 4.9 versus 7 +/- 3). The > duration of OAH was similar on both study nights (20 +/- 1.9 s during > C versus 20 +/- 1.5 s during OPA). The frequency of movement arousals > terminating OAH tended to be higher during OPA (7 +/- 2.9/h) than > during C (3 +/- 0.7); P = NS. The frequency of oxyhemoglobin > desaturations was also higher during OPA (5 +/- 2.1/h) than during C > (3 +/- 1.4), p less than 0.07. > > PMID: 2008992, UI: 91181783 > ________________________________________________________________ > > Other Formats: [Citation Format] [MEDLINE Format] > Links: [109 medline neighbors] > > Am Rev Respir Dis 1985 Nov;132(5):972-5 > >The effects of nasal anesthesia on breathing during sleep. > > White DP, Cadieux RJ, Lombard RM, Bixler EO, Kales A, Zwillich CW > > Inability to breathe through the nose is an increasingly recognized > cause of disordered breathing during sleep. To test the hypothesis > that this respiratory dysrhythmia could result from loss of neuronal > input to respiration from receptors located in the nose, we > anesthetized the nasal passages of 10 normal men during sleep. Each > subject spent 4 consecutive nights in the sleep laboratory while > sleep stages, breathing patterns, respiratory effort, and arterial > oxygen saturation were monitored. Night 1 was for acclimatization > with Nights 3 and 4 being randomized to nasal spraying with either 4% > lidocaine or placebo. On the lidocaine and placebo nights (Nights 3 > and 4) the nasal passages were also sprayed with a decongestant to > prevent increased nasal air-flow resistance resulting from mucosal > swelling. To control for the possible effects of this decongestant, > an additional night (Night 2) was included during which the nasal > passages were sprayed with room air. Parallel studies conducted > during wakefulness demonstrated low nasal resistance during the > lidocaine-decongestant regimen. Because of the short duration of > anesthesia with lidocaine, spraying was done at lights out and 2.5 > and 5 h later. On the placebo night (decongestant plus saline) there > were 6.4 +/- 1.8 (SEM) disordered breathing events (apneas plus > hypopneas) per subject, whereas with lidocaine (plus decongestant) > this increased fourfold to 25.8 +/- 7.8 events per subject (p less > than 0.05). The majority of the disordered breathing events were > apneas and were fairly evenly distributed between central and > obstructive events. The magnitude of these changes is similar to that > previously reported with complete nasal obstruction. These results > suggest that nasal receptors sensitive to air flow may be important > in maintaining breathing rhythmicity during sleep. > > Publication Types: > * Clinical trial > * Randomized controlled trial > > PMID: 4062052, UI: 86048887 this document > > Am J Perinatol 1987 Apr;4(2):164-6 > >Lidocaine toxicity after maternal pudendal anesthesia in a term infant with >fetal distress. > > Bozynski ME, Rubarth LB, Patel JA > > There have been many reports of lidocaine toxicity especially after > maternal paracervical block anesthesia. We recently treated a term > infant with evidence of fetal distress who presented with symptoms of > lidocaine toxicity after maternal pudendal anesthesia. The infant > developed apnea and bradycardia soon after birth which responded to > mechanical ventilation and epinephrine. A prolonged Q-T interval was > noted on day 1 which normalized by day 3. Cord blood was assayed and > revealed an elevated lidocaine level. Lidocaine toxicity has been > associated with fetal distress secondary to fetal ion trapping in the > presence of acidosis. Although good response to supportive therapy > occurred in our patient, other methods of therapy such as exchange > transfusion and treatment of seizures may be required in some cases. > Awareness of this now uncommon syndrome will lead to prompt > diagnosis, appropriate work-up, and management. > > PMID: 3566884, UI: 87184830 > ________________________________________________________________ > > Other Formats: [Citation Format] [MEDLINE Format] > Links: [169 medline neighbors] > > Am J Physiol 1977 Jul;233(1):R30-6 > >Properties of the laryngeal chemoreflex in neonatal piglets. > > Lee JC, Stoll BJ, Downing SE > > Cardiorespiratory reflex responses to laryngeal chemoreceptor > stimulation were studied in 62 piglets of both sexes varying in age > from 1 to 79 days. The distal trachea was cannulated to provide a > free airway and the proximal end used to introduce fluids into the > laryngeal area. Introduction of either water or milk produced apnea, > bradycardia, and hypertension. Swab application of test fluids to the > laryngeal epithelium produced similar responses. The reflex could be > interrupted by flushing the laryngeal region with saline, by cutting > the superior laryngeal nerves (SLN) or by anesthetizing the laryngeal > epithelium with lidocaine. Electrical stimulation of SLN elicited > identical responses. Respiratory inhibition by the reflex was > enhanced following central depression with chloralose and overridden > by administration of the respiratory stimulant, aminophylline. The > relative potency of the laryngeal reflex was estimated to be > equivalent to about 40% of the dose of chloralose which produced > permanent respiratory arrest. It is concluded that in circumstances > where respiratory drive is reduced the laryngeal inhibitory reflex is > capable of caused persistent apnea and asphyxial death in the young > piglet. > > PMID: 18025, UI: 77219523 > ________________________________________________________________ > > Other Formats: [Citation Format] [MEDLINE Format] > Links: [102 medline neighbors] > > Rev Bras Pesqui Med Biol 1976 Dec;9(5-6):229-37 > >Lethal effect of the serotonin-xylocaineR association in ganglion-blocked >rats. > > Valle LB, Oliveira-Filho RM, Armonia PL, Saraceni G Jr, Nassif M, De >Lucia R > > In rats anestetized with urethane and under ganglionic blockade by > hexamethonium (20 mg/kg, i.v.), the i.v. injection of serotonin (60 > mug/kg) determined apnea, ECG alterations and a brief hypotensive > response which is similar to that as elicited when 5-HT is given to > intact rats. During the hypertension which follows that initial > response, apnea is still present along with more severe ECG changes. > After that, blood pressure falls into a prolonged hypotension, which > is invariably accompanied by death. Neither norepinephrine, nor > respiratory analeptics (CoramineR, RemeflinF) were able to prevent > the fatal outcome. Only artificial respiration was found to be useful > in some instances. It was concluded that the association serotonin > plus lidocaine becomes lethal when given to ganglion-blocked rate, > and this toxic effect can be ascribed mainly to the respiratory > depressor activity of the drugs. > > PMID: 1013401, UI: 77103742 > ___________________________ > Z Orthop Ihre Grenzgeb 1974 Oct;112(5):1053-62 > From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Path: biosci!rutgers!rockyd.rockefeller.edu!newsfeed.nyu.edu!feeder.qis.net!news.maxwell.syr.edu!newsfeed.cwix.com!24.92.226.85!newsf1.twcny.rr.com!newsr1.twcny.rr.com.POSTED!not-for-mail From: ZZZghull@stny.lrun.com (Jerry Hull) Newsgroups: alt.brain,alt.human-brain,bionet.general,bionet.neuroscience,comp.ai.philosophy,sci.bio.misc,sci.cognitive,sci.philosophy.meta,sci.philosophy.tech Subject: Re: machine brains Message-ID: <36b76a45.4511757@news-server> References: <36a5d8ea.0@ns2.wsg.net> <784vkd$pmt$1@pegasus.csx.cam.ac.uk> <36a73cc5.0@ns2.wsg.net> <787me7$gcl$1@pegasus.csx.cam.ac.uk> <36abd06d.0@ns2.wsg.net> <78ir9a$ovj$1@pegasus.csx.cam.ac.uk> <36af4849.0@ns2.wsg.net> <78q0rp$5on$1@pegasus.csx.cam.ac.uk> <36b5cfd6.0@ns2.wsg.net> <797j77$c3r$1@garnet.mint.net> <36bc5261.4648534@news.demon.co.uk> X-Newsreader: Forte Free Agent 1.11/32.235 Lines: 19 Date: Tue, 02 Feb 1999 21:13:31 GMT NNTP-Posting-Host: 204.210.146.103 X-Trace: newsr1.twcny.rr.com 917989561 204.210.146.103 (Tue, 02 Feb 1999 16:06:01 EDT) NNTP-Posting-Date: Tue, 02 Feb 1999 16:06:01 EDT Organization: TWC Syracuse NY Xref: biosci bionet.general:32240 bionet.neuroscience:27565 On Tue, 02 Feb 1999 21:08:16 GMT, malcolm@pigsty.demon.co.uk (Malcolm McMahon) wrote: >On Tue, 2 Feb 1999 14:20:40 -0500, "William Thomas" >wrote: > >>I often wonder how an eagle, with very little brain power left over after >>accounting for optics, can accurately make the complex physics calculations >>required for a 100mph+, 1000' dive to snag a fish that is swimming under >>water while the defecated light creates an optical illusion as to the >>position of the fish that varies depending on the fish's depth, the water >>clarity, and the intensity and angle of the sun. You gotta look out for that defecated light! -- Jer "However far you may travel in this world, you will still occupy the same volume of space". Traditional Ur-Bororo saying. From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Path: biosci!rutgers!rockyd.rockefeller.edu!newsfeed.nyu.edu!news.idt.net!feed1.news.rcn.net!rcn!woodstock.news.demon.net!demon!news.demon.co.uk!demon!pigsty.demon.co.uk!not-for-mail From: malcolm@pigsty.demon.co.uk (Malcolm McMahon) Newsgroups: alt.brain,alt.human-brain,bionet.general,bionet.neuroscience,comp.ai.philosophy,sci.bio.misc,sci.cognitive,sci.philosophy.meta,sci.philosophy.tech Subject: Re: machine brains Date: Tue, 02 Feb 1999 21:08:16 GMT Message-ID: <36bc5261.4648534@news.demon.co.uk> References: <36a5d8ea.0@ns2.wsg.net> <784vkd$pmt$1@pegasus.csx.cam.ac.uk> <36a73cc5.0@ns2.wsg.net> <787me7$gcl$1@pegasus.csx.cam.ac.uk> <36abd06d.0@ns2.wsg.net> <78ir9a$ovj$1@pegasus.csx.cam.ac.uk> <36af4849.0@ns2.wsg.net> <78q0rp$5on$1@pegasus.csx.cam.ac.uk> <36b5cfd6.0@ns2.wsg.net> <797j77$c3r$1@garnet.mint.net> NNTP-Posting-Host: pigsty.demon.co.uk X-NNTP-Posting-Host: pigsty.demon.co.uk:158.152.84.59 X-Trace: news.demon.co.uk 917989738 nnrp-01:9443 NO-IDENT pigsty.demon.co.uk:158.152.84.59 X-Complaints-To: abuse@demon.net X-Newsreader: Forte Agent 1.5/32.451 MIME-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit Lines: 40 Xref: biosci bionet.general:32239 bionet.neuroscience:27564 On Tue, 2 Feb 1999 14:20:40 -0500, "William Thomas" wrote: >I often wonder how an eagle, with very little brain power left over after >accounting for optics, can accurately make the complex physics calculations >required for a 100mph+, 1000' dive to snag a fish that is swimming under >water while the defecated light creates an optical illusion as to the >position of the fish that varies depending on the fish's depth, the water >clarity, and the intensity and angle of the sun. > I've got an idea how these things might work, but I don't think you're going to like it:-) Regard the future as an quantum superposition of possibilities. It's possible the bird might catch the fish, it's possible it might hit the water wrong and break every bone in it's body and there are many intermediate possibilities. All these things are possible both in terms of the aerodynamics of the situaion and in terms of the circuitry of the bird's brain. The past, on the other hand, is fixed and singular. Suppose "now" is not, as we usually regard it, only an instant wide but up to several seconds. The span of time, in fact, between the fixed past and the distance into the future where the multiplication of possibilities becomes, in some sense, unmanageable. Suppose that the bird's will _choses_ one of the possible paths through the now on the basis, not of the method of achivement, but of the outcome. Having chosen the superposition collapses along the length of the now and the now becomes part of the past and a new now provides the next set of choices. (I go into this wild theory at more length on http://www.pigsty.demon.co.uk/time.html) From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Path: biosci!MSN.COM!rcb5 From: rcb5@MSN.COM ("Ron Blue") Newsgroups: bionet.neuroscience Subject: Freedom of speech is not absolutely protected Date: 2 Feb 1999 12:08:40 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 20 Sender: daemon@net.bio.net Distribution: world Message-ID: <008501be4ee7$1731bca0$671bfbd0@default> NNTP-Posting-Host: net.bio.net >: There's an old saying by Will Rogers: "Often the smartest >: thing to do is shut up and mind your own business". I would say >: it's pretty good advice for Mr. Johnson to follow. >>>>> It is important from a legal point of view to notice that freedom of speech is not absolute. You can not yell "fire" in a theater that is not on fire. You can not damage another financial or their standing in the community with false statements as determined by the legal process, not the opinion of truth as determined by the individual. Normally, in the legal process, no one pays the legal expenses of another because almost any opinion of reality is likely to have some merit. Ron Blue From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Path: biosci!rutgers!rockyd.rockefeller.edu!newsfeed.nyu.edu!news.maxwell.syr.edu!newsfeed.cwix.com!204.254.98.218!mint.net!not-for-mail From: "William Thomas" Newsgroups: alt.brain,alt.human-brain,bionet.general,bionet.neuroscience,comp.ai.philosophy,sci.bio.misc,sci.cognitive,sci.philosophy.meta,sci.philosophy.tech Subject: Re: machine brains Date: Tue, 2 Feb 1999 14:20:40 -0500 Organization: Maine InternetWorks Lines: 21 Message-ID: <797j77$c3r$1@garnet.mint.net> References: <36a5d8ea.0@ns2.wsg.net> <784vkd$pmt$1@pegasus.csx.cam.ac.uk> <36a73cc5.0@ns2.wsg.net> <787me7$gcl$1@pegasus.csx.cam.ac.uk> <36abd06d.0@ns2.wsg.net> <78ir9a$ovj$1@pegasus.csx.cam.ac.uk> <36af4849.0@ns2.wsg.net> <78q0rp$5on$1@pegasus.csx.cam.ac.uk> <36b5cfd6.0@ns2.wsg.net> NNTP-Posting-Host: ddialup-r-271.mint.net X-Newsreader: Microsoft Outlook Express 4.72.3110.1 X-MimeOLE: Produced By Microsoft MimeOLE V4.72.3110.3 Xref: biosci bionet.general:32238 bionet.neuroscience:27562 I often wonder how an eagle, with very little brain power left over after accounting for optics, can accurately make the complex physics calculations required for a 100mph+, 1000' dive to snag a fish that is swimming under water while the defecated light creates an optical illusion as to the position of the fish that varies depending on the fish's depth, the water clarity, and the intensity and angle of the sun. Also, how can Michael Jordan's brain calculate the physics of his movements fast enough, and process the dynamic feedback from multiple senses and various appendages to create one of his typical now you see it now you don't dunks. Forget about souls - this stuff is already hard enough to understand without adding in things we can't even define! Anyone have any thoughts on cellular intelligence? the great molecular binary system? From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Path: biosci!agate!newsfeed.berkeley.edu!news2.best.com!news1.best.com!sdd.hp.com!col.hp.com!fc.hp.com!dlc From: dlc@fc.hp.com (Dennis Clark) Newsgroups: comp.ai.philosophy,bionet.neuroscience,comp.robotics.misc,comp.sys.amiga.programmer,comp.lang.cobol Subject: Re: The Art of Computer Mindmaking Followup-To: comp.ai.philosophy,bionet.neuroscience,comp.robotics.misc,comp.sys.amiga.programmer,comp.lang.cobol Date: 2 Feb 1999 19:17:15 GMT Organization: Hewlett-Packard Fort Collins Site Lines: 27 Message-ID: <797ivr$o1v$3@fcnews.fc.hp.com> References: <36b4e81d.0@news.victoria.tc.ca> <5EGt2.2582$Xl5.3042071@news1.mia> NNTP-Posting-Host: hpmckee.fc.hp.com X-Newsreader: TIN [version 1.2 PL1.4] Thane Hubbell (redsky@ibm.net) wrote: : On Tue, 2 Feb 1999 17:31:45, "Judson McClendon" : wrote: : > Arthur T. Murray wrote: : > [snip] : > > Soon, when Mind.forth "quickens" or comes full circle in its ... : > [snip] : > Such we have been hearing from the AI folks for decades. Soon ... : > Actually it's been Looooooooooonnnnnnnnnng, and we're stilllll... : > waiting. But Soon ... : You may not know this, but Mr Murray is a Turing machine. You are : talking to an AI! : (Actually, I don't know that to be a fact.... but it could be......... Sounds like that Mentaflex chap that was so annoying a while back and landed in my kill file. It bugs me to look up someones nostrils while he insists on using $5 words to describe a 10 cent idea. It makes my head hurt. DLC -- ------------------------------------------------------------ | Dennis Clark (970)898-4313 email dlc@fc.hp.com | | Hewlett Packard Ft. Collins NSD Ft. Collins CO 80525 | | Be well, Do good work, stay in touch -- Garrison Keillor | ------------------------- CUT HERE ------------------------- From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Path: biosci!news.stanford.edu!news.ems.psu.edu!news3.cac.psu.edu!newsserver.jvnc.net!198.138.0.5!newshub.northeast.verio.net!fu-berlin.de!cijadra.dialup.fu-berlin.DE!not-for-mail From: cijadra@zedat.fu-berlin.de (Cijadrachon) Newsgroups: bionet.neuroscience Subject: Private comment Date: Mon, 01 Feb 1999 19:06:38 GMT Organization: Freie Universitaet Berlin Lines: 4 Message-ID: <36b5f8b0.5858025@news.zedat.fu-berlin.de> NNTP-Posting-Host: cijadra.dialup.fu-berlin.de (130.133.216.34) Mime-Version: 1.0 Content-Type: text/plain; charset=iso-8859-1 Content-Transfer-Encoding: 8bit X-Access: 16 17 18 X-Trace: fu-berlin.de 917980074 29461 (none) 130.133.216.34 X-Newsreader: Forte Free Agent 1.11/16.235 Wanna alter something to do with the computer, but given the inherent evil viciousness of thingies and my ever so superb skills with such I don't know if I fubar it; so should there be replies lacking it is not meant as ignoring. :-) From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Path: biosci!news.stanford.edu!logbridge.uoregon.edu!howland.erols.net!rill.news.pipex.net!pipex!ams.uu.net!uunet!ffx.uu.net!in2.uu.net!not-for-mail From: redsky@ibm.net (Thane Hubbell) Newsgroups: comp.ai.philosophy,bionet.neuroscience,comp.robotics.misc,comp.sys.amiga.programmer,comp.lang.cobol Subject: Re: The Art of Computer Mindmaking Date: 2 Feb 99 19:57:53 GMT Lines: 19 Message-ID: References: <36b4e81d.0@news.victoria.tc.ca> <5EGt2.2582$Xl5.3042071@news1.mia> NNTP-Posting-Host: 208.214.67.251 Mime-Version: 1.0 Content-Type: text/plain; charset="us-ascii" Content-Transfer-Encoding: 8bit X-Newsreader: ProNews/2 Version 1.50 Beta 1 On Tue, 2 Feb 1999 17:31:45, "Judson McClendon" wrote: > Arthur T. Murray wrote: > [snip] > > Soon, when Mind.forth "quickens" or comes full circle in its ... > [snip] > > Such we have been hearing from the AI folks for decades. Soon ... > Actually it's been Looooooooooonnnnnnnnnng, and we're stilllll... > waiting. But Soon ... You may not know this, but Mr Murray is a Turing machine. You are talking to an AI! (Actually, I don't know that to be a fact.... but it could be......... ) From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Path: biosci!agate!newsfeed.berkeley.edu!news.maxwell.syr.edu!fu-berlin.de!cijadra.dialup.fu-berlin.DE!not-for-mail From: cijadra@zedat.fu-berlin.de (Cijadrachon) Newsgroups: bionet.neuroscience Subject: To F.Frank LeFever, Ph.D. etc. Date: Mon, 01 Feb 1999 18:52:15 GMT Organization: Freie Universitaet Berlin Lines: 51 Message-ID: <36b5e975.1958790@news.zedat.fu-berlin.de> NNTP-Posting-Host: cijadra.dialup.fu-berlin.de (130.133.216.34) Mime-Version: 1.0 Content-Type: text/plain; charset=iso-8859-1 Content-Transfer-Encoding: 8bit X-Access: 16 17 18 X-Trace: fu-berlin.de 917979213 29461 (none) 130.133.216.34 X-Newsreader: Forte Free Agent 1.11/16.235 >Sorry for eg.3ing rather unconstructively at times. >I am not used to taking you serious, unless you quote fact data. >Reminding me: >Which drug stuff did you want me on back then exactly? >How about you tell me, and if I am in the mood I smurf to some >chemo-fryer here and tell him your name and that you said that I >should try that, and that therefore I like to check it out. >Might be fun and might tell me volumes about your healer smurf >capacities and your eg.3 over logic dangers to others. >How about instead of vague words you either apologize for that one >or tell me exactly which stuff and what it is, into which systems it >goes, what it does there, what are the damages it does, and then tell >me what damages that heals? BTW, I was serious about that. You know my opinion about you as a healer in still limited for me still polite form, and a lot the real one you could not even understand because you do not have the education / the basics for it. (Apart from that there'd be too much impolite stuff in it.) I figure if I try that stuff then I see even better how "suited" you are as a healer. I suspect lovely discussion options might sprout from there. ;-)= (And I am already curious if that might be going to be some drowner, "shut-up-drug" or happy pill or other system disturber, as I somehow doubt that you just invented the after concussion super drug or some serious improvement for the form of MBD I have.) I could go to a local chemo-shrink here and tell him "F.Frank Le Fever, Ph.D. (etc.) recommended I take ..." and ask him to prescribe the stuff, my insurance should cover that. I could leave out that you said it in one of your censoring phases and wanted to shut me up, else he might not prescribe it and believe you just some immature idiot from the USA who does not have his rank fighting drives under control. So what stuff were/are you referring to, and what does it do exactly in which area(s) and what do you believe that it will improve? ... Unless of course if are whom I rate a coward, and evade standing to your word or seriously apologizing for your according remarks back then. From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Path: biosci!agate!newsfeed.berkeley.edu!howland.erols.net!outgoing.news.rcn.net.MISMATCH!feed1.news.rcn.net!rcn!newsfeed.atl!upstream.atl!news1.mia.POSTED!not-for-mail From: "Judson McClendon" Newsgroups: comp.lang.cobol,comp.ai.philosophy,bionet.neuroscience,comp.robotics.misc,comp.sys.amiga.programmer References: <36b4e81d.0@news.victoria.tc.ca> Subject: Re: The Art of Computer Mindmaking Lines: 16 Organization: Sun Valley Systems X-Newsreader: Microsoft Outlook Express 4.72.3155.0 X-MimeOLE: Produced By Microsoft MimeOLE V4.72.3155.0 Message-ID: <5EGt2.2582$Xl5.3042071@news1.mia> Date: Tue, 02 Feb 1999 17:31:45 GMT NNTP-Posting-Host: 209.214.105.133 NNTP-Posting-Date: Tue, 02 Feb 1999 12:31:45 EDT Arthur T. Murray wrote: [snip] > Soon, when Mind.forth "quickens" or comes full circle in its ... [snip] Such we have been hearing from the AI folks for decades. Soon ... Actually it's been Looooooooooonnnnnnnnnng, and we're stilllll... waiting. But Soon ... -- Judson McClendon judmc123@bellsouth.net (remove numbers) Sun Valley Systems http://personal.bhm.bellsouth.net/~judmc "For God so loved the world that He gave His only begotten Son, that whoever believes in Him should not perish but have everlasting life." From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Path: biosci!news.stanford.edu!newsfeed.berkeley.edu!newspeer.monmouth.com!solomon.io.com!news.tamu.edu!fox.tamu.edu!not-for-mail From: wej3715@fox.tamu.edu (Walter Eric Johnson) Newsgroups: bionet.neuroscience Subject: Re: Dyslexic Artist Astounds Theoreticians Date: 2 Feb 1999 05:38:45 GMT Organization: Texas A&M University, College Station, Texas Lines: 20 Message-ID: <796315$h3g$1@news.tamu.edu> References: <7951de$qs4$1@news.tamu.edu> <19990201205022.06436.00003161@ng14.aol.com> NNTP-Posting-Host: unix.tamu.edu NNTP-Posting-Date: 2 Feb 1999 05:38:45 GMT X-Newsreader: TIN [UNIX 1.3 950824BETA PL0] JTyburczy (jtyburczy@aol.com) wrote: : <> : : Not the truth. Your very first action was to file a complaint with AOL : regarding my posting several harmless newsgroup pointers to a competely : noncommercial site. Only after this did you attempt to contact me via "private" : email. (Sort of a "shoot 'em in the back first, then ask questions later" : method you got there, eh?) My normal practice when complaining about spam is to do one of the following: 1) Complain to the spammer and cc the ISP or 2) Complain to the ISP and cc the spammer. I made no exception in your case. Only after you posted my private e-mail twice did I complain to AOL without cc'ing you. Eric Johnson From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Path: biosci!agate!newsfeed.berkeley.edu!awabi.library.ucla.edu!164.67.43.25!news.ucla.edu!pool0024-max7.ucla-ca-us.dialup.earthlink.net!user From: cheney@ucla.edu (Michael C. Cheney) Newsgroups: bionet.neuroscience Subject: Re: Dolphin brain Date: Mon, 01 Feb 1999 22:04:27 -0800 Organization: UCLA Computer Science Lines: 62 Message-ID: References: <19990123184419.27486.00001075@ngol03.aol.com> NNTP-Posting-Host: pool0024-max7.ucla-ca-us.dialup.earthlink.net X-Newsreader: Yet Another NewsWatcher 2.0b27.5 In article , "Tim Tillman" wrote: | | Bottem line is that intelligence alone is not sufficient to ensure fitness. No one trait is sufficient to insure fitness. Every functioning gene in the vast human genome has contributed to fitness in one way or another. But I do think that the innate ability to learn is a very important factor in vertibrate fitness. I think you have been postulating that intelligence is not selected for, and that the evidence for this is the fact that human intelligence hasn't changed in the last few thousand years. I think you could argue that very little has changed evolutionarily in ANY animal in that time frame. So this is hardly evidence for or against intelligence being influential in natural selection. | dinner over the threat of the net. I have never seen, but also never looked | for, data that would lead anyone to believe that a pod of dolphins, after | seeing members drowned in nets, would communicate to members that it would | be better to avoid the easy netted cod. | | >Is there evidence for | >this? I was under the impression (mistaken perhaps) that if a dolphin was | >caught in a net, and then set free, that the dolphin would avoid the area | >where it was first caught. | | The individual dolphin might avoid an area where he narrowly escaped death. | But will it choose life over that afore mentioned cod? Wait, so you are just _assuming_ that dolphins probably do things that seem stupid to you? Isn't that sort of circular logic? What would the dolphin do? something stupid. how do you know its stupid? Because I thought it would do that stupid thing. | | > Also, are you saying that communication is a | >prerequisite to your definition of intellegence? | | No. Development of language may be indicative of intelligence. It would be | difficult to describe an individual human born without the necessary brain | anatomy to utilize language in some fashion as intelligent. Communication | is a valuable ability. But, I did not equate communication with language. but you said that dolphins weren't intellegent because they didn't tell the rest of the pod about the fishing nets. what if they just can't communicate, or they don't have the necessary vocabulary to describe the problem? They may be smart, but not have language... (from another post) | That a kitten seems to know to use a litter box does not imply intelligence. I think the fact that you (or the kittens mother) can teach the kitten to use a litter box certainly does imply intelligence. -mike -- Michael Cheney cheney@ucla.edu From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Path: biosci!uvi.edu!rhall From: rhall@uvi.edu (Richard Hall) Newsgroups: bionet.neuroscience Subject: Re: Dolphin brain Date: 2 Feb 1999 05:49:07 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 79 Sender: daemon@net.bio.net Distribution: world Message-ID: References: <7pqt2.150$aC6.601@news5.ispnews.com> NNTP-Posting-Host: net.bio.net Well done. rlh At 6:02 PM -0500 2/1/99, Tim Tillman wrote: >Krakatoa wrote in message >news:stephan-0102991313120001@we-24-130-93-57.we.mediaone.net... > > >>The fact that you are writing this post is ample evidence that >>intelligence has in fact increased; humans of 50-200,000 years ago were >>completely incapable of this behavior or this level of analysis in any >>way; they would score lower on any intelligence test, even one that was >>designed for them. There is no legimate intelligence defintion you could >>use which would not give you that humans today are more intelligent. > >Lacking an encyclopedia at my desk, I resort to Encarta 98 ... > >"intelligence, capacity to learn or to understand. It is generally >synonymous >with intellect but is usually differentiated from intellect in practice to >emphasize ability or efficiency in dealing with concrete situations and in >profiting intellectually from sensory experience." > >Would you reject this definition of intelligence? By this definition, >intelligence is not a measure of accumulated knowledge, but rather as stated >above a 'capacity to learn or to understand.' To say that intelligence is >increasing over time is not measurable, however our say that the amount of >accumulated knowledge is increasing over time is a given. > >There is no evidence that dolphin populations accumulate knowledge. What >skills do they pass on to other generations? What history? What lore? >Great apes and man can teach successive generations. Great apes are less >intelligent than man not because man has accumulated his vast amount of >knowledge, but rather because mankind's capacity to learn is higher, than >that of the great apes. > >That a kitten seems to know to use a litter box does not imply intelligence. >That plants exhibit geotropism and phototropism does not imply intelligence. >That members of species come together for mating does not imply >intelligence. > >>You choose to reject this because you know that human biology probably has >>not changed much over the same time period, but this is not a good reason >to >>reject it. I could take two identical twins, raise one in an isolated >>impoverished prison, and the other at Oxford, and the Oxford raised twin >>would be MUCH MORE intelligent than the one raised in a prison. I don't >>think I need to repeat this point. > >Just as you may take orphaned identical twins from a third world country, >raise one on a subsistance diet, the other on standard American fair. The >child raised in America will be stronger, taller, and overall healthier. In >the twins is is the genetic capacity, analogous to intelligence, to grow >strong. This capacity is only exploited in the environment that can support >it. In your case above, both have the inate capacity to learn. But only in >the Oxford sibling is that capacity exploited. Therefore, they are of equal >intelligence. > >>Some traits that contribute intelligence are heritable, these components >>probably include genes which contribute to the ability to learn. > >And some genetic defects are detrimental to the ability to learn. > >>I would argue there is already very good evidence that the abililtiy to >learn can >>strongly affect reproductive fitness, ergo, natural selection has probably >>favored them. The fact that these learning mechanisms are so highly >>conserved in the entire phylum (e.g., CREB) suggests that they are very >>strongly associated with fitness. > >Tim Richard Hall Comparative Animal Physiologist Division of Sciences and Mathematics University of the Virgin Islands St. Thomas, USVI 00802 809-693-1386 rhall@uvi.edu From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Path: biosci!uvi.edu!rhall From: rhall@uvi.edu (Richard Hall) Newsgroups: bionet.neuroscience Subject: Re: Dolphin brain Date: 2 Feb 1999 05:47:14 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 51 Sender: daemon@net.bio.net Distribution: world Message-ID: References: NNTP-Posting-Host: net.bio.net At 1:13 PM -0800 2/1/99, Krakatoa wrote: >> >> >In article , rhall@uvi.edu >>(Richard >> >> >Hall) wrote: >> >> > >> >> >| Natural selection does not appear to favor humans or dolphins of >>extreme >> >> >| intelligence...at least there is no evidence that the mean has >> >>shifted one >> >> >| way or the other. It is only sufficient that animals possess >>sufficient >> >> >[snip, snip] >The fact that you are writing this post is ample evidence that >intelligence has in fact increased; humans of 50-200,000 years ago were >completely incapable of this behavior or this level of analysis in any >way; they would score lower on any intelligence test, even one that was >designed for them. There is no legimate intelligence defintion you could >use which would not give you that humans today are more intelligent. > >Cheers, >Stephan Hi Stephan, You can repeat your point as often as you wish. However, your criteria for "intelligence", ie., the ability to write, supposes that such a skill would have been relevant 50,000-200,000 years ago. Clearly circumstances have changed, but just because early Homo sapiens did not write or use a computer does not mean they lacked intelligence to solve problems. How many "civilized" folks could survive in a pretechnological world in the absence of information accumulated over the past 5,000 years? In that setting early Homo sapiens would probably fare better and by your sliding scale of intelligence would be more intelligent. The twin studies were invalidated because of fraud, but even so it is irrelevant because there is no way to test infants born 200,000 years ago or to raise them in controlled circumstances. Ditto dolphins. Again there is no credible evidence either way on this argument and the entire issue is frankly silly arm chair speculation. rlh Richard Hall Comparative Animal Physiologist Division of Sciences and Mathematics University of the Virgin Islands St. Thomas, USVI 00802 809-693-1386 rhall@uvi.edu From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Newsgroups: bionet.neuroscience Path: biosci!news.stanford.edu!logbridge.uoregon.edu!sunqbc.risq.qc.ca!newspeer.monmouth.com!baron.netcom.net.uk!netcom.net.uk!server3.netnews.ja.net!ucl.ac.uk!bcc.ac.uk!news From: Ivo Kwee Subject: Re: Dolphin brain, language, and intelligence Sender: news@ucl.ac.uk (Usenet News System) Message-ID: <36B6E488.3655@medphys.ucl.ac.uk> Date: Tue, 2 Feb 1999 11:42:00 GMT Content-Transfer-Encoding: 7bit Content-Type: text/plain; charset=us-ascii References: <19990123184419.27486.00001075@ngol03.aol.com> Mime-Version: 1.0 X-Mailer: Mozilla 3.02 (Win16; I) Organization: University College London, Medical Physics & Bioengineering Lines: 48 Tim Tillman wrote: > > << .....cut out ... >>> > > > Also, are you saying that communication is a > >prerequisite to your definition of intellegence? > > No. Development of language may be indicative of intelligence. It would be > difficult to describe an individual human born without the necessary brain > anatomy to utilize language in some fashion as intelligent. Communication > is a valuable ability. But, I did not equate communication with language. > > Microorganisms can communicate by chemical signals. The pressence of these > signals will induce the population to act in a certain way. Inducing > biolumenescence pathways and aggregation of slime mold individuals into > reproductive structures come to mind. This form of communication is not > considered a language. Languages are vocal or symbolic in some form, and > allow the transfer of complex ideas. Languages are not chemical. Many > animals communicate vocally. Do we assign the vicious growling of a dog to > language? I think not. Its communication goal is purely instinctive. The > dance of the honey bee can communicate the location of nectar. But, this is > not language. This is the communication of a concrete fact, not complex > ideas. Great apes and humans can communicate complex ideas. > > Tim Maybe ultimately it _is_ the prime objective for "general communication" to establish a link between brains. The most _direct_ way in chemical or electrically such as in micro-organims. But chemical diffusion or electrical conductivity is low in air, so animals "developed" sound and language as a link between brains. This means that it is no good to say "having a language" is intelligent. Micro-organisms don't need vocal language because they have better. Language is prone to misinterpretation while chemical and electrical signals (in some sense ...) are not. Ivo -- Ivo Kwee, Department of Medical Physics and Bioengineering, University College London. Office: 0171 - 209 6415 Fax: 0171 - 209 6269 Home: 0171 - 794 5243 E-mail: kwee@medphys.ucl.ac.uk From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Path: biosci!news.stanford.edu!newsfeed.berkeley.edu!cyclone.swbell.net!nntp.giganews.com!solomon.io.com!news.tamu.edu!scully.tamu.edu!not-for-mail From: wej3715@scully.tamu.edu (Walter Eric Johnson) Newsgroups: bionet.neuroscience Subject: Re: Dyslexic Artist Astounds Theoreticians Date: 2 Feb 1999 08:18:12 GMT Organization: Texas A&M University, College Station, Texas Lines: 20 Message-ID: <796cc4$162$1@news.tamu.edu> References: <795ro2$omi@sjx-ixn6.ix.netcom.com> <19990202022833.00995.00002872@ng-fa1.aol.com> NNTP-Posting-Host: unix.tamu.edu NNTP-Posting-Date: 2 Feb 1999 08:18:12 GMT X-Newsreader: TIN [UNIX 1.3 950824BETA PL0] JarryLaw (jarrylaw@aol.com) wrote: : In truth, an organization (i.e., a University) could : theoretically be named as the defendant in a lawsuit : involving the actions of an individual in its employ, : especially if the individual is utilizing an instrument : of University communications (in this instance, an : Internet account) in his official capacity as an instructor : with intent to harass or otherwise inhibit the free : speech of other individuals. For what it's worth, I'm a student at Texas A&M, not an employee. : There's an old saying by Will Rogers: "Often the smartest : thing to do is shut up and mind your own business". I would say : it's pretty good advice for Mr. Johnson to follow. You're probably quite right about that. Eric Johnson From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Path: biosci!news.stanford.edu!su-news-feed2.bbnplanet.com!su-news-hub1.bbnplanet.com!cpk-news-hub1.bbnplanet.com!news.gtei.net!news-peer.gip.net!news.gsl.net!gip.net!portc01.blue.aol.com!audrey03.news.aol.com!not-for-mail From: jarrylaw@aol.com (JarryLaw) Newsgroups: bionet.neuroscience Subject: Re: Dyslexic Artist Astounds Theoreticians Lines: 38 NNTP-Posting-Host: ladder03.news.aol.com X-Admin: news@aol.com Date: 2 Feb 1999 07:28:33 GMT Organization: AOL http://www.aol.com References: <795ro2$omi@sjx-ixn6.ix.netcom.com> Message-ID: <19990202022833.00995.00002872@ng-fa1.aol.com> flefever@ix.netcom.com(F. Frank LeFever) wrote: <> True, but only if said suits can be proven to be unmerited and ruled upon as frivolous within the process of a legal proceeding. As an attorney I can see several factors that would warrant serious attention to this case in favor of BIOSOUND. In truth, an organization (i.e., a University) could theoretically be named as the defendant in a lawsuit involving the actions of an individual in its employ, especially if the individual is utilizing an instrument of University communications (in this instance, an Internet account) in his official capacity as an instructor with intent to harass or otherwise inhibit the free speech of other individuals. With this in mind, the suit becomes even more viable when the evidence of Mr. Johnson's well-recorded proclivity for needlessly harassing posters within Internet newsgroups is presented. In the case of a successful pursuance, judgement could include fines and penalties that range from simple censure to dismissal/loss of tenure from the University, and of course, the bearing of all legal costs associated with the proceeding. There's an old saying by Will Rogers: "Often the smartest thing to do is shut up and mind your own business". I would say it's pretty good advice for Mr. Johnson to follow. Alfred Jarrey, Esq. From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 From: xc11@cornell.edu (Jack Chen) Newsgroups: bionet.neuroscience Subject: Powerful DNA analysis tool at http://128.84.203.244 Date: Tue, 02 Feb 1999 03:34:04 GMT Organization: Cornell Lines: 7 Sender: xc11@cornell.edu (Verified) Message-ID: <795rkk$cpo@newsstand.cit.cornell.edu> NNTP-Posting-Host: d6018.dialup.cornell.edu X-Newsreader: News Xpress 2.01 Path: biosci!news.stanford.edu!newsfeed.berkeley.edu!news.maxwell.syr.edu!news.syr.edu!newsstand.cit.cornell.edu!cu-dialup Powerful DNA analysis tool at http://128.84.203.244 DNAClub 1.5 for Windows 95/NT/98, Freeware for Mol-biol guys DNA sequence editting, find, find ORF, remove vector seq, translation, RE Mapping, PCR primer selection and evluation, multiple DNA/protein sequence alignment. From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Path: biosci!news.stanford.edu!newsfeed.berkeley.edu!newsfeed.enteract.com!ix.netcom.com!news From: flefever@ix.netcom.com(F. Frank LeFever) Newsgroups: bionet.neuroscience Subject: Re: (none) Date: 2 Feb 1999 03:24:19 GMT Organization: Netcom Lines: 55 Message-ID: <795r53$ibi@dfw-ixnews11.ix.netcom.com> References: <000701be4da4$84308460$542910ce@jeremy> NNTP-Posting-Host: nyc-ny64-35.ix.netcom.com X-NETCOM-Date: Mon Feb 01 9:24:19 PM CST 1999 Tell us more. Is this the scam in Switzerland? In <000701be4da4$84308460$542910ce@jeremy> jblackburn@LGCY.COM ("Jeremy Blackburn") writes: > >This is a multi-part message in MIME format. > >------=_NextPart_000_0004_01BE4D69.D6DD8860 >Content-Type: text/plain; > charset="iso-8859-1" >Content-Transfer-Encoding: quoted-printable > >I am interested in any information about Glen Doman and the IAHP. We = >have twin daughters we both have some special needs, and are currently = >considering our options. =20 > >Jblackburn@lgcy.com > > >------=_NextPart_000_0004_01BE4D69.D6DD8860 >Content-Type: text/html; > charset="iso-8859-1" >Content-Transfer-Encoding: quoted-printable > > > > > >http-equiv=3DContent-Type> > > > >
I am interested in any information about Glen Doman = >and the=20 >IAHP.  We have twin daughters we both have some special needs, and = >are=20 >currently considering our options. 
>
 
>
href=3D"mailto:Jblackburn@lgcy.com">Jblackburn@lgcy.com >
 
> >------=_NextPart_000_0004_01BE4D69.D6DD8860-- > From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Path: biosci!news.stanford.edu!newsfeed.berkeley.edu!newsfeed.enteract.com!ix.netcom.com!news From: flefever@ix.netcom.com(F. Frank LeFever) Newsgroups: bionet.neuroscience Subject: Re: Dyslexic Artist Astounds Theoreticians Date: 2 Feb 1999 03:34:26 GMT Organization: Netcom Lines: 64 Message-ID: <795ro2$omi@sjx-ixn6.ix.netcom.com> References: <19990128191437.00998.00000304@ng-fa1.aol.com> <19990201124138.07822.00003181@ng-fr1.aol.com> NNTP-Posting-Host: nyc-ny64-35.ix.netcom.com X-NETCOM-Date: Mon Feb 01 7:34:26 PM PST 1999 If I understand the following correctly, BIOSOUND is seeking to censor free expression by threatening to sue anyone who criticizes their product(s). I do not think a university can be sued for "being responsible for training an incompetent and hiring him", cannot imagine any ethical lawyer purporting to initiate such a suit or any court entertaining it, but such irresponsible threats tend to have a chilling effect on public discourse and should be soundly condemned by all readers of this newsgroup, as well as by the service internet service providers involved. Am I right in thinking that people bringing frivolous and patently unmerited suits can suffer penalties for doing so? including but not limited to paying all legal costs? I urge you all to let Mr. Howe know what you think of his actions. F. LeFever In <19990201124138.07822.00003181@ng-fr1.aol.com> jtyburczy@aol.com (JTyburczy) writes: > >THE MANY TARGETS OF "NEWSGROUP NUISANCE" ERIC JOHNSON. ARE YOU ONE? > >Earlier this month he blasted BIOSOUND for being "off topic" in a newsgroup (a >favorite pastime of the truly powerless, BTW). Then, when it was pointed out he >hadn't really understood the material, he proceeded to publicly disparage their >products, causing BIOSOUND management to post the following: > >******** > >From Jerry Howe >Organization BIOSOUND Scientific >Date Sun, 24 Jan 1999 17:44:27 GMT >Newsgroups rec.pets.dogs.behavior >Message-ID <36AB5BBA.B14D9F3B@bellsouth.net> > >---------------------------------------------------------------------- - > >I am making an exception to the statement I gave you on 12/28, that I would not >respond to >your posts. > >The reason I will not respond to you is because BIOSOUND Scientific is seeking >legal action >against you and Texas A&M University for their being responsible for training >an incompetent >and employing him. > >Jerry Howe, >Director of Research, >BIOSOUND Scientific > Biosound@aol.com > From owner-neuroscience@net.bio.net Mon Feb 01 22:00:00 1999 Path: biosci!news.stanford.edu!newsfeed.berkeley.edu!news.maxwell.syr.edu!netnews.netreach.net!usenet From: "scott" Newsgroups: bionet.neuroscience,bionet.nih,bionet.parasitology,bionet.prof-society,bionet.prof-society.faseb Subject: US-MD LABORATORY SPACE for LEASE Date: Mon, 1 Feb 1999 22:12:32 -0800 Organization: NetReach InterNetNews Lines: 17 Message-ID: <795qr9$jk0$5@tikehau.netreach.net> NNTP-Posting-Host: ppp-207022-102.netreach.net X-Newsreader: Microsoft Outlook Express 4.72.3110.5 X-Mimeole: Produced By Microsoft MimeOLE V4.72.3110.3 Xref: biosci bionet.neuroscience:27544 bionet.parasitology:3787 AMAZING LAB SPACE in BALTIMORE, MARYLAND Pharmaceutical Research & Development Facility AVAILABLE FOR IMMEDIATE LEASE >Lab space from 500-1,000-5,000-20,000-64,000 SF >Prices from $25-$40 Per Square Foot >Full service, Turn-key Labs >Short & Long Term Leases Available For More Information CALL: Rob Freedman Corridor Commercial Real Estate Group, Inc. (410) 363-9500 x109 corridorre@aol.com From owner-neuroscience@net.bio.net Tue Feb 02 22:00:00 1999 Path: biosci!news.stanford.edu!newsfeed.berkeley.edu!chippy.visi.com!news-out.visi.com!hub1.ispnews.com!news5.ispnews.com.POSTED!not-for-mail From: "Tim Tillman" Newsgroups: bionet.neuroscience References: <19990123184419.27486.00001075@ngol03.aol.com> Subject: Re: Dolphin brain Lines: 18 X-Priority: 3 X-MSMail-Priority: Normal X-Newsreader: Microsoft Outlook Express 5.00.0810.800 X-MimeOLE: Produced By Microsoft MimeOLE V5.00.0810.800 Message-ID: NNTP-Posting-Host: 208.153.131.24 X-Trace: news5.ispnews.com 918007347 208.153.131.24 (Tue, 02 Feb 1999 21:02:27 EDT) NNTP-Posting-Date: Tue, 02 Feb 1999 21:02:27 EDT Organization: ISPNews http://ispnews.com Date: Tue, 2 Feb 1999 21:01:01 -0500 In a previous post, I wrote the following: "Witness the "dumb jock" in high school. He may bed tens of girls while in high school on the five year plan. He may unwittingly become a father due to his exploitations. That offspring has a greater chance of coming into existance, than one fathered by a super genius who lacks other qualities. That offspring, by virtue of its existance, has an infinately better chance of reproducing, than the non-existent offspring of a super genius who lacks other qualities." After giving a bit of thought to my previous statement, I have this to offer. The super genius may not contribute his own genes to the population, but his pressence might enable the group to faie better. He may discover a safe way to dispose of nuclear waste. He may cure the common cold. He may end world hunger. Group selection in action. From owner-neuroscience@net.bio.net Tue Feb 02 22:00:00 1999 Path: biosci!news.stanford.edu!logbridge.uoregon.edu!howland.erols.net!nntp.abs.net!hub1.ispnews.com!news5.ispnews.com.POSTED!not-for-mail From: "Tim Tillman" Newsgroups: bionet.neuroscience References: <19990123184419.27486.00001075@ngol03.aol.com> <36B6E488.3655@medphys.ucl.ac.uk> <36b71c96.259162896@news.udel.edu> Subject: Re: Dolphin brain, language, and intelligence Lines: 16 X-Priority: 3 X-MSMail-Priority: Normal X-Newsreader: Microsoft Outlook Express 5.00.0810.800 X-MimeOLE: Produced By Microsoft MimeOLE V5.00.0810.800 Message-ID: NNTP-Posting-Host: 208.153.131.24 X-Trace: news5.ispnews.com 918006855 208.153.131.24 (Tue, 02 Feb 1999 20:54:15 EDT) NNTP-Posting-Date: Tue, 02 Feb 1999 20:54:15 EDT Organization: ISPNews http://ispnews.com Date: Tue, 2 Feb 1999 20:52:43 -0500 justus wrote in message news:36b71c96.259162896@news.udel.edu... >So lets put in another possibel semantic confound: >how about the different apparen abilities between organisms within and >between species to abtsract? > >Justus Exactly what do you mean? Can you give intraspecies and interspecies examples of what you are talking about? Tim From owner-neuroscience@net.bio.net Tue Feb 02 22:00:00 1999 Message-ID: <36B83A54.1ACA@antibodyresource.com> Date: Wed, 03 Feb 1999 06:00:32 -0600 From: The Antibody Resource Page X-Mailer: Mozilla 3.01-C-MACOS8 (Macintosh; I; PPC) MIME-Version: 1.0 Newsgroups: bionet.neuroscience Subject: Are you looking for an Antibody? Visit the Antibody Resource Page! Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit NNTP-Posting-Host: master1-77.dialup.chi.idsonline.com Lines: 19 Path: biosci!rutgers!rockyd.rockefeller.edu!news-nysernet-5.sprintlink.net!news.sprintlink.net!news-east1.sprintlink.net!news-peer1.sprintlink.net!-program!news-peer.gip.net!news.gsl.net!gip.net!cpk-news-hub1.bbnplanet.com!chicago-news-feed1.bbnplanet.com!news.gtei.net!news.idsonline.com!master1-77.dialup.chi.idsonline.com The Antibody Resource Page (http://www.antibodyresource.com/) now maintains a list of custom antibody suppliers. If you are interested in the production of custom monoclonal or polyclonal antibodies see this invaluable guide at: http://www.antibodyresource.com/customantibody.html Also, take a look our "How to Find an Antibody" section (http://www.antibodyresource.com/customantibody.html) which outlines a variety of ways online and offline to locate your antibody of interest. This section has links to online antibody search engines and reference manuals such as the MSRS Catalog of Primary Antibodies and Linscott's Directory. Don't forget to visit our other sections on educational resources and stop by to see our antibody gallery. ps. The ARP was voted among the top 25 biotechnology webpages for 1997 by Genetic Engineering News! From owner-neuroscience@net.bio.net Tue Feb 02 22:00:00 1999 Path: biosci!agate!newsfeed.berkeley.edu!newsfeed.enteract.com!newsswitch.lcs.mit.edu!rill.news.pipex.net!pipex!uu.fr!imaginet.net!imaginet.fr!usenet From: "vermeim" Newsgroups: bionet.neuroscience Subject: Int Sympo Mol Genetics of Mental Disorders Date: Wed, 3 Feb 1999 10:50:17 +0100 Organization: ImagiNET Lines: 9 Message-ID: <7995dv$t3g$1@news.imaginet.fr> NNTP-Posting-Host: 195.68.9.174 X-Newsreader: Microsoft Outlook Express 4.71.1712.3 X-MimeOLE: Produced By Microsoft MimeOLE V4.71.1712.3 International Symposium "Molecular Genetics of Mental Disorders" Date : December 1-3, 1999 Castres (Tarn) France The final scientific program is now available on http://www.entretiens-du-carla.com From owner-neuroscience@net.bio.net Tue Feb 02 22:00:00 1999 Path: biosci!news.stanford.edu!logbridge.uoregon.edu!newspeer1.nac.net!news.maxwell.syr.edu!news-peer.gip.net!news.gsl.net!gip.net!portc01.blue.aol.com!audrey01.news.aol.com!not-for-mail From: jarrylaw@aol.com (JarryLaw) Newsgroups: bionet.neuroscience Subject: Re: Dyslexic Artist Astounds Theoreticians Lines: 11 NNTP-Posting-Host: ladder01.news.aol.com X-Admin: news@aol.com Date: 3 Feb 1999 03:11:38 GMT Organization: AOL http://www.aol.com References: <19990202183849.27832.00003580@ng112.aol.com> Message-ID: <19990202221138.12955.00002097@ng102.aol.com> <<>> Great page. AJ From owner-neuroscience@net.bio.net Tue Feb 02 22:00:00 1999 Path: biosci!MSN.COM!rcb5 From: rcb5@MSN.COM ("Ron Blue") Newsgroups: bionet.neuroscience Subject: interacting wavelets Date: 2 Feb 1999 18:57:33 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 12 Sender: daemon@net.bio.net Distribution: world Message-ID: <008501be4f1f$63ee61a0$241bfbd0@default> NNTP-Posting-Host: net.bio.net People have occasionally asked what is the effect of interacting stimulus wavelets on the nervous system. The below picture illustrates the concept without sine and cosine graphs. Ron Blue THE WIZARD OF FRENCHMAN'S BAY http://members.aol.com/jrubu/noyes.htm From owner-neuroscience@net.bio.net Tue Feb 02 22:00:00 1999 Path: biosci!news.stanford.edu!newsfeed.berkeley.edu!news.maxwell.syr.edu!nntp.news.xara.net!xara.net!server5.netnews.ja.net!daresbury!not-for-mail From: John Shawe-Taylor Newsgroups: bionet.neuroscience Subject: Informal pre-EuroCOLT'99 Workshop on Kernel Methods Date: 3 Feb 1999 17:38:11 -0000 Organization: Daresbury Laboratory, Warrington, U.K. Lines: 18 Message-ID: <79a1i3$j6s$1@mserv2.dl.ac.uk> NNTP-Posting-Host: mserv2.dl.ac.uk Mime-Version: 1.0 Original-To: "'Camelia Voinea - Black Sea University'" , "'colt'" , "'comp-neuro'" , "'connectionists'" , "'NC2-all'" , "'neuron-request'" , "'neur-sci'" content-length: 602 Return-Path: X-Sender: john@sartre.cs.rhbnc.ac.uk We are hosting a one day informal workshop on Sunday 28th March at Nordkirchen Castle, Germany, on the Sunday before the EuroCOLT'99 conference; particular interest of the organisers is the analysis of Kernel Methods and this will be one of the themes of the workshop. To find out more information and registration procedures please go to the web site: http://svm.first.gmd.de/eurocolt99/workshop.html Organizing Committee John Shawe-Taylor, john@dcs.rhbnc.ac.uk Alex J. Smola, smola@first.gmd.de Bernhard. Schoelkopf, bs@first.gmd.de Robert C. Williamson, Bob.Williamson@anu.edu.au From owner-neuroscience@net.bio.net Tue Feb 02 22:00:00 1999 Path: biosci!news.stanford.edu!newsfeed.berkeley.edu!news.maxwell.syr.edu!wn4feed!worldnet.att.net!135.173.83.225!attworldnet!newsadm From: "Gilbert Groehn" Newsgroups: bionet.neuroscience Subject: >>>RESEARCH EQUIPMENT SALE<<< Date: 3 Feb 1999 22:55:27 GMT Organization: ULTRAMED, INC Lines: 812 Message-ID: <01be4fc7$3f3cfbc0$8e404c0c@fpfzqlga> Reply-To: ultramedco@worldnet.att.net NNTP-Posting-Host: 12.76.64.142 Mime-Version: 1.0 Content-Type: multipart/mixed; boundary="----=_NextPart_000_01BE4F9D.5666F3C0" Content-Transfer-Encoding: 7bit X-Newsreader: Microsoft Internet News 4.70.1155 This is a multi-part message in MIME format. ------=_NextPart_000_01BE4F9D.5666F3C0 Content-Type: text/plain; charset=ISO-8859-1 Content-Transfer-Encoding: 7bit Our fourteen page list of currently available surplus research equipment is attached as a text file. There are items for physiology, neurology (several EEG's and Evoked Potential units), lots of MICROSCOPES, top of the line ultrasound equipment, lab gear, electronics, AND MUCH MORE. Hope we can help with your research equipment needs, Ultramed, Inc. Gil Groehn ------=_NextPart_000_01BE4F9D.5666F3C0 Content-Type: application/octet-stream; name="LIST.txt" Content-Transfer-Encoding: quoted-printable Content-Description: List (Text Document) Content-Disposition: attachment; filename="LIST.txt" U L T R A M E D, I N C. Grosse Pointe Farms MI 48236 USA 313-884-1139 email: ultramedco@worldnet.att.net ****NOTICE**** ULTRAMED, INC. has available for immediate sale equipment as described in attached INVENTORY LIST NO. 99111. All equipment has been used in research and/or clinical applications. Note: complete list is approx. twelve pages. Many of these items are priced as low as ten percent of original cost. We believe that this represents exceptional value for quality equipment from leading manufacturers. The equipment is believed to be=20 in very good to excellent operating condition but is offered on an AS IS basis at these prices. Call or write for further information. Thanking you and hoping that we may be able to help with your equipment needs. INVENTORY LIST NO. 99111 ULTRASOUND EQUIPMENT ******************** ACUSON 128-XP10 Ultrasound system. With color doppler and color B-Mode. Comes with L-558 (5.0 Mhz Linear), S-519 (5.0 Mhz Sector), V-328 (3.5 Mhz Vector/sector), and S-228 (2.5 Phased ) Probes, VTR and Matrix or EII B/W camera. Software Rev. 23.143. ACUSON ultrasound equipment is known for "gold standard image quality" and excellent reliability. INQUIRE SHIMADZU Model SDU-700 Sector/Linear Diagnostic Ultrasound System. = With Doppler and (1) 3.5 Mhz Sector Probe, (1) 2.5 Mhz Sector probe with = CW/PW Doppler, (1) Sony UP-850 printer and optional VTR. Does echo- cardiography, general purpose abdominal applications, and doppler echo. This is an exceptionally clean system with very versatile capabilities. All imaging probes are phased array sector type for trouble free = imaging. EXCEPTIONAL VALUE INQUIRE BIOSOUND "PHASE II" Vascular imaging system. With 10 Mhz PHASAR probe. Extremely high resolution vascular imaging. Ideal for research and/or general vascular imaging. Both in-line and side-looking doppler. Biosound 256 gray level technology and ultra-high (0.2mm) resolution provide exceptional image clarity and detail. (2) units are available. INQUIRE =09 TOSHIBA 'Sonolayer' Model SAL-38AS General purpose Linear/Sector ultraound imaging system. With 3.0 Mhz Linear probe (PLB-310M) and 3.5 Mhz sector probe (SM-308M). OB Calculations software. INQUIRE PHILIPS Model SDR-1200 Portable ultrasound imaging system with 3.5 Mhz imaging probe (LA-3510) Comes with cart and additional=20 monitor. INQUIRE PROSCAN by TEKNAR (Now Carolina Electronics) Prostate scanner with bi-plane trans-rectal probe. $3,750.00 = =20 ATL MK-450 Ultrasound system. General purpose imaging and doppler when used with Model 721B or 724B scanhead. Furnished with 721B (3.0Mhz) scanhead. Others available. No VTR. Comes with ATL multi-format camera. $1,200.00 = ATL MK-300I General purpose ultrasound system. Comes with Multi-format camera and choice of 720A or 723A scanhead. $1,000.00 = ATL PROBES Models 722A and 723A for MK-300/MK-450 systems. call for = $ ATL Model 724A Multi Frequency probe for MK-300/450 (2) call for = $ IMEX Model 301-P Vascular doppler system with 8.0 Mhz. doppler transducer and strip chart recorder. $ 750.00 =20 MEDASONICS 'Versatone' Fetal & Vascular doppler. 2.0 & 5.0Mhz. $ 350.00 = IMEX "POCKET DOP-II" Fetal heart beat dopplers ( 3.0 Mhz). Can also be used for vascular work with 8Mhz probe available from IMEX. $ 300.00 = Ea MULTIGON Model 500A CW doppler unit. Can be used for vascular and umbilical cord doppler studies. An integral spectrum=20 analyzer provides bi-directional doppler traces and output can be recorded on VTR or Printer (not included). Comes with=20 5.0 Mhz CW doppler probe. $650.00 PARKS Model 806-CA Bi-Directional doppler with 9.0 Mhz probe. $500.00 HEMODAYNAMICS Model AV-1000 Peripheral vascular diagnostic system. Designed to indicate the presence of deep vein thrombosis or venus incompetence. This system uses Light Reflection Rheography to measure microscopic changes in the dermal plexus that occur when a limb is exercised. Operation is similar to photo plethysmography or impedance plethysmography but the mfg. claims more sensitivity. INQUIRE =09 MATRIX 1010-6 VIDEO IMAGER. The 1010-6 is a six on one microprocessor controlled multi format imager for use with ultrasound, C-Arms, Nuclear medicine and other electronic imaging systems. Uses 8" x 10" BW film. INQUIRE = =20 PHYSIOLOGICAL MONITORS *********************** SPACELABS Model 90623A ECG, (2) Pressure (2) Temperature and respiration channel. With 90651 recorder. Trend feature. $ = 850.00 SPACELABS Model 90623A Same as above except no recorder. $ = 600.00 SPACELABS Model 90603A ECG, (2) Pressure (2) Temperature and pulse (plethysmography type) with 90651 recorder and trend. $ = 850.00 SPACELABS Model 514 with 551 recorder. Does ECG, Pulse, (2) Pressure and temperature. Has trend feature. $ = 750.00 SPACELABS (Tektronix) Model 414 Opt. 21 Monitor. $ = 425.00 AIR-SHIELDS Model AS-461 Neonatal monitor. No recorder. $ = 450.00=20 Designed to monitor ECG, Respiration, Apnea and Temp. HEWLETT-PACKARD Model 78354-C Patient monitor. ECG with trends amd two invasive pressure channels. No recorder output. This is the latest of the 78534 series monitors. $ 950.00 HEWLETT-PACKARD Model 78354-A Patient monitor. ECG with non-invasive blood pressure and one channel of invasive pressure. With H.P. Model 78173W strip chart recorder. = $1,250.00 HEWLETT-PACKARD Model 78353-A Patient Monitor. ECG, (2) invasive pressures, (2) Temperature inputs. * $ = 650.00 With H.P. Model 78172A (2) channel recorder.* = $1,000.00 H.P. 78339 carts are also available. HEWLETT-PACKARD Model 78801 Neonate monitors. ECG, RESP and some have invasive B.P. (2) available. Ideal VET units. $ = 450.00 PULSE OXIMETERS *************** DATASCOPE 'ACCUSAT' Pulse Oximeter. With Finger probe. $ 500.00 NELLCOR N-100C Pulse Oximeters. 5 button model. Can supply with or without preamp cable and finger sensor. INQUIRE STRESS TEST SYSTEMS ******************* MARQUETTE "CASE 12" Stress Test System with Marquette 1800 treadmill. System is in exceptional condition. = $6,800.00 HOLTER MONITORS *************** DMI "SIMPLICITY-I" Compact full disclosure holter monitor. Provides a full disclosure report automatically. Comes with a Spacelabs Model 90205 Holter recorder.. = $2,450.00 HOLTER RECORDERS Spacelabs Models 90205 and 90201 INQUIRE TELEMETRY SYSTEMS ***************** MENNEN Telemetry system. (4) Patient system with (4) transmitters and central station receiver w/ recorder. = $1,600.00 QUINTON Q-TEL-400 Telemetry system. Four channel system with Three transmitters included. Many features. = $2,250.00 HEWLETT-PACKARD Telemetry sets Model 78100/78101. Transmitter and matching receiver. (6) available) $ = 450.00 ea HEWLETT-PACKARD OB/GYN TELEMETRY SETS. HP-78120 Transmitter with TOCO and Ultrasound transducers. 78100 receiver with 80140 adapter for connection to 8040 Fetal monitor. Can be used as stand alone units (for research applications only) with suitable power supply for 80140. (2) sets available $ = 500.00 ea VET MEDICINE MONITORS ********************* HEWLETT-PACKARD 78801B Neonate monitors. These are ideal for vet medicine. ECG, pressure and respiration channels. $ = 450.00 Ea TEKTRONIX 413A Neonate monitors. ECG, Pressure and Respiration.$ = 350.00 Ea TEKTRONIX 408 ECG monitors. Basic unit. $ 200.00 MENNEN Model 744 Patient Monitors. ECG only. Storage scope. $ = 285.00 Ea MENNEN Patient Monitor with recorder. Does ECG & Respiration. $ = 375.00 D MENNEN Model 740 with recorder. ECG only. $ = 475.00=20 Note: Patient cables are not included with VET monitors but we can supply customized cable sets with alligator clips or other electrodes of your choice at additional cost. ELECTROCARDIOGRAPHS - ECG's *************************** HEWLETT-PACKARD Model 4760A 'PAGEWRITER' Electrocardiograph. Full alphanumeric keyboard to input Patient data. Advanced signal processing and internal ECG storage. Convenient one page records of 12 lead ECG. Full operator control over recording formats. $1,500.00 CARDIOLINE 'DELTA 30D' compact INTERPRETIVE 12 lead ECG. $1,250.00 =20 NIHON-KOHDEN Model ECG-8240A "Cardio-Fax V" INTERPRETIVE (12) lead ECG. Compact unit with the world renowned quality of Nihon-Kohden. Many features. = $1,700.00 FUKUDA-DENSHI Model FCP-2201A 12 lead INTERPRETIVE ECG. Nice compact unit. AC or Battery operation. Many features. $1,250.00 CAMBRIDGE VS-550 EKG single channel. $ = 350.00 CAMBRIDGE (Picker) Model CM-3000 ten lead (3) channel ECG $ = 650.00 BURDICK E-310 ten lead (3) channel ECG. = $1,150.00 TELEMED three channel, (12)lead electrocardiograph. $ = 350.00 D MARQUETTE MAC-I three channel 12 lead EKG. $ = 350.00 D CAMBRIDGE VS-500 Single Channel ECG. Some cosmetic damage on case but works fine. Good Vet unit. $ = 200.00 FUKUDA-DENSHI compact portable ECG. Battery operated with ac charger. (4" X 6" X 9") Ideal for field work. (1) channel $ = 275.00 SEISMED "SEISMOCARDIOGRAPH" Model SCG-2000. This is a highly specialized instrument that combines ECG with SEISMOCARDIOGRAPHY for increased diagnostic accuracy. A preliminary multi center trial validated this technology in 1992. This unit sold for over $20,000.00 in 1992 and appears in pristine condition. Ideal for research. = $1,200.00 MONITORS & RECORDERS ********************* HEWLETT-PACKARD Model 78171A Strip Chart Recorder. $ = 150.00 HEWLETT-PACKARD Model 78534C Monitor/Terminal with 78553A Pressure module. Does (2) Channels of EKG and Two Pressures and Two Temperature inputs. $ = 750.00 STRIP CHART RECORDERS: a variety of H.P. recorders are available. = INQUIRE NON-INVASIVE BLOOD PRESSURE MONITORS ************************************ PHYSIO-CONTROL 'Lifestat 200' NIBP with printer. $ = 750.00 AIR-SHEILDS (Healthdyne) Model BP-203NA. NIBP with printer. $ = 350.00 DATASCOPE ACCUTOR-2A NIBP monitor (no printer) $ = 650.00 CRITIKON Model 847XT Neonate N.I.B.P. monitors. Ideal for veterinary medicine. $ = 550.00 Ea CRITIKON Model 845 N.I.B.P. monitor. With hose and cuff. $ = 450.00 PHYSIO-CONTROL 'LIFESTAT 100' NIBP. With charger. This unit is 'beat up' cosmetically but works fine. $ = 200.00 KENDALL System 9200 N.I.B.P. monitors with cuff. $ = 225.00 D DEFIBRILLATORS ************** HEWLETT-PACKARD Model 43110A with monitor and strip chart recorder. (3) units available = INQUIRE =20 HEWLETT-PACKARD Model 78660A Defibrillator with monitor strip chart recorder and charger. = INQUIRE HEWLETT-PACKARD Model 78619 Defibrillator. NO MONITOR. = INQUIRE HEWLETT-PACKARD Model 78672A Defibrillator NO MONITOR with Model 78668 charger base. INQUIRE Note: Operating (open heart) paddles are available for the 43110A defibs. DEFIBRILLATORS sold only to qualified EMS, BIOMED or other medical professionals. NEUROLOGY EQUIPMENT ****