From owner-p450@hgmp.mrc.ac.uk Tue Mar 5 14:50:30 2002 Return-Path: Received: from localhost (localhost [127.0.0.1]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 7928617BBF for ; Tue, 5 Mar 2002 14:50:28 +0000 (GMT) Received: from localhost (localhost [127.0.0.1]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id A181217BC0 for ; Tue, 5 Mar 2002 14:50:21 +0000 (GMT) Received: from niobium.hgmp.mrc.ac.uk (niobium [193.62.192.41]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id CE2BC17BBB for ; Tue, 5 Mar 2002 14:50:15 +0000 (GMT) Received: (from news@localhost) by niobium.hgmp.mrc.ac.uk (8.9.3+Sun/8.8.8) id OAA07042 for p450-list@hgmp.mrc.ac.uk; Tue, 5 Mar 2002 14:41:37 GMT X-Authentication-Warning: niobium.hgmp.mrc.ac.uk: news set sender to using -f From: irpikule@utmb.edu ("Pikuleva, Irina") X-Newsgroups: bionet.molecules.p450 Subject: US/TX Postdoctoral Position in Protein Crystallography of P450s Date: 5 Mar 2002 14:41:36 -0000 Organization: BIOSCI/MRC Human Genome Mapping Project Resource Centre Lines: 36 Message-ID: Mime-Version: 1.0 Content-Type: text/plain; charset=windows-1252 X-Complaints-To: news@net.bio.net Content-return: allowed X-Received: from localhost (localhost [127.0.0.1]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 76C4617ACF for ; Tue, 5 Mar 2002 14:41:34 +0000 (GMT) X-Received: from is1.utmb.edu (mx2.utmb.edu [129.109.195.2]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 2CFF817A68 for ; Tue, 5 Mar 2002 14:41:30 +0000 (GMT) X-Return-Receipt-To: irpikule@utmb.edu X-Received: from exchange3.utmb.edu (email.utmb.edu [129.109.52.245]) by utmb.edu (PMDF V6.1 #38124) with ESMTP id <0GSI00MFH8S6DW@utmb.edu> for p450@net.bio.net; Tue, 05 Mar 2002 08:40:54 -0600 (CST) X-Received: by exchange3 with Internet Mail Service (5.5.2653.19) id ; Tue, 05 Mar 2002 08:41:28 -0600 X-To: "'p450@net.bio.net'" X-Mailer: Internet Mail Service (5.5.2653.19) To: p450@hgmp.mrc.ac.uk Sender: owner-p450@hgmp.mrc.ac.uk Precedence: bulk US/TX Postdoctoral Position in Protein Crystallography of P450s Applications are invited for a postdoctoral position in X-ray crystallography at the University of Texas Medical Branch. The position is available for applicants with research experience in either protein crystallography, who want to gain experience in crystallization of membrane proteins, or those with experience in biochemistry, who want to learn protein crystallography. The project will focus on improvement of the quality of the crystals of three membrane-bound cytochromes P450 (P450 7A1, 27A1 and 11A1) followed by determination of their structures. P450s 7A1 and 27A1 play key roles in degradation of cholesterol to bile acids, the major pathway of cholesterol disposal from the body, whereas P450 11A1 catalyses the conversion of cholesterol to pregnenolone, the first and rate limiting step in steroid hormone biosynthesis. Expression, purification and crystallization of P450s will be carried out in the laboratory of Irina Pikuleva (http://www2.utmb.edu/phtox/facres/pikuleva/index.htm). Analysis of crystals, data processing, phase determination, model building and protein structure refinement will be carried out under the supervision of Dr. Robert O. Fox (http://www.hbcg.utmb.edu/faculty/fox/index.html), the Director of the X-ray Crystallography Center at UTMB (http://www.hbcg.utmb.edu/xray/). X-ray and computational facilities include a MacScience imaging plate detector, a Siemens 2K CCD detector, two rotating anode X-ray generators, and access to a MAD beamline at the CAMD synchrotron, SGI computers and graphic workstations, and a Cray J90 supercomputer. Initial appointment is for one year and then renewable. Salary is competitive and based on the NIH guidelines. UTMB is located at Galveston Island, 2 miles off the Texas mainland and 50 miles southeast of Houston. UTMB is an equal opportunity/affirmative action employer, M/F/D/V. Please submit CV and contact information for three references to: Dr. I. Pikuleva, Dept. of Pharmacology & Toxicology, University of Texas Medical Branch, 301 University Blvd., Galveston, TX 77555-1031, USA. Phone (409)772-9657, fax (409)772-9642, mailto://irpikule@utmb.edu. --- From owner-p450@hgmp.mrc.ac.uk Mon Mar 11 01:20:40 2002 Return-Path: Received: from localhost (localhost [127.0.0.1]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 91F1217A61 for ; Mon, 11 Mar 2002 01:20:39 +0000 (GMT) Received: from localhost (localhost [127.0.0.1]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id C93F817A97 for ; Mon, 11 Mar 2002 01:20:35 +0000 (GMT) Received: from niobium.hgmp.mrc.ac.uk (niobium [193.62.192.41]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id AC01617A61 for ; Mon, 11 Mar 2002 01:20:33 +0000 (GMT) Received: (from news@localhost) by niobium.hgmp.mrc.ac.uk (8.9.3+Sun/8.8.8) id BAA20913 for p450-list@hgmp.mrc.ac.uk; Mon, 11 Mar 2002 01:18:53 GMT X-Authentication-Warning: niobium.hgmp.mrc.ac.uk: news set sender to using -f From: heather691@cranfield.ac.uk X-Newsgroups: bionet.molecules.p450 Subject: Hello Tim Date: 11 Mar 2002 01:18:51 -0000 Organization: BIOSCI/MRC Human Genome Mapping Project Resource Centre Lines: 11 Message-ID: <200203110116.g2B1GtJ30034@mywebready.com> X-Complaints-To: news@net.bio.net X-Received: from localhost (localhost [127.0.0.1]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 83CC117A97 for ; Mon, 11 Mar 2002 01:18:48 +0000 (GMT) X-Received: from mywebready.com (unknown [64.215.52.110]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 88C8C17A83 for ; Mon, 11 Mar 2002 01:18:45 +0000 (GMT) X-Mailer: Microsoft Outlook, Build 10.0.2616 X-Reply-To: X-To: To: p450@hgmp.mrc.ac.uk Sender: owner-p450@hgmp.mrc.ac.uk Precedence: bulk Tim, It was great to talk to you today I should have the propsal done by tommorrow Take Care, Susan --- From owner-p450@hgmp.mrc.ac.uk Thu Mar 14 14:06:00 2002 Return-Path: Received: from localhost (localhost [127.0.0.1]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 456E317ABC for ; Thu, 14 Mar 2002 14:05:59 +0000 (GMT) Received: from localhost (localhost [127.0.0.1]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 81E5317A8A for ; Thu, 14 Mar 2002 14:05:56 +0000 (GMT) Received: from niobium.hgmp.mrc.ac.uk (niobium [193.62.192.41]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id E55DF17ABC for ; Thu, 14 Mar 2002 14:05:45 +0000 (GMT) Received: (from news@localhost) by niobium.hgmp.mrc.ac.uk (8.9.3+Sun/8.8.8) id NAA28619 for p450-list@hgmp.mrc.ac.uk; Thu, 14 Mar 2002 13:52:43 GMT X-Authentication-Warning: niobium.hgmp.mrc.ac.uk: news set sender to using -f Reply-To: "People-Reach Consulting" From: "People-Reach Consulting" X-Newsgroups: bionet.molecules.p450 Subject: Toronto-Senior Research Scientist-P450s Lines: 56 X-Priority: 3 X-MSMail-Priority: Normal X-Newsreader: Microsoft Outlook Express 5.50.4807.1700 X-MimeOLE: Produced By Microsoft MimeOLE V5.50.4807.1700 Message-ID: Date: Thu, 14 Mar 2002 13:52:41 GMT X-Complaints-To: abuse@nbnet.nb.ca Organization: NBTel Internet To: p450@hgmp.mrc.ac.uk Sender: owner-p450@hgmp.mrc.ac.uk Precedence: bulk Do you have a Ph.D. with a focus in dermatology or Vitamin D biochemistry? Does the thought of working on a world-class team actively developing cutting-edge therapeutics for psoriasis, acne and photo-aging with a particular emphasis on Vitamin D metabolic pathways appeal to you? Are you interested in working with industry, but want to keep your status within the scientific community? If so, this position will be of interest to you. My client is a rapidly growing biotechnology company involved in the discovery of small molecule therapeutic agents targeting a physiologically important class of enzymes known as cytochrome P450s. They are currently seeking creative, innovative research scientists with a background in dermatology or Vitamin D biochemistry to join their dermatology team in Toronto. You will participate in the development of novel therapeutics in dermatology with particular emphasis on vitamin D metabolic pathways. This may include pre-clinical testing of proprietary drugs using in vitro assays and the development of functional assays. The ideal candidate will have a Ph.D in a relevant discipline, and will have demonstrated expertise in Vitamin D biochemistry or dermatology (psoriasis, ketatinocytes) as well as a passion for continuously seeking out new and innovative technologies. Experience in the pharmaceutical or biotechnology industry and previous supervisory experiences are assets. In return for your skills and expertise you will receive an above industry average salary and benefits package as well as a stock option plan. The work environment is challenging and stimulating and both team and individual accomplishments are rewarded. You will also have the opportunity to be involved in discovery research - from discovery right through to product development. And you will have the opportunity to remain active in scientific research community - publication is encouraged by the employer. Relocation expenses are also provided. If you are interested in the above position, please e-mail your resume in confidence to Liane Thibodeau at liane@people-reach.com. We will treat any inquiry or resume received with the utmost confidentiality. Under no circumstances will we submit your resume to any client without your prior approval. If you are not personally interested in this opportunity, but know of someone who might be, please pass the posting on. We do pay a referral fee for candidates who are placed successfully. Thank you for your time and I look forward to hearing from you. -- Liane Thibodeau People-Reach Consulting Reaching People and Developing Potential http://www.people-reach.com 50 Summerville Road, Summerville, NB E5S 1G7 Tel: (506) 763-3655 Fax: (506) 763-3656 Toll-Free: 1-888-265-1001 From owner-p450@hgmp.mrc.ac.uk Sat Mar 23 13:21:17 2002 Return-Path: Received: from localhost (localhost [127.0.0.1]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id B6FDA17A4E for ; Sat, 23 Mar 2002 13:21:16 +0000 (GMT) Received: from localhost (localhost [127.0.0.1]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 9ED2517A43 for ; Sat, 23 Mar 2002 13:21:14 +0000 (GMT) Received: from niobium.hgmp.mrc.ac.uk (niobium [193.62.192.41]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 107D517A4E for ; Sat, 23 Mar 2002 13:21:11 +0000 (GMT) Received: (from news@localhost) by niobium.hgmp.mrc.ac.uk (8.9.3+Sun/8.8.8) id NAA27350 for p450-list@hgmp.mrc.ac.uk; Sat, 23 Mar 2002 13:07:25 GMT X-Authentication-Warning: niobium.hgmp.mrc.ac.uk: news set sender to using -f From: brenda_malik@lycos.com X-Newsgroups: bionet.molecules.p450 Subject: re: new extensions now available Date: 23 Mar 2002 13:07:23 -0000 Organization: BIOSCI/MRC Human Genome Mapping Project Resource Centre Lines: 45 Message-ID: <028e31b70a7c$4382d7d5$5ca45bc1@ggspwa> Mime-Version: 1.0 Content-Type: text/plain; charset="iso-8859-1" Content-Transfer-Encoding: 8bit X-Complaints-To: news@net.bio.net X-Received: from localhost (localhost [127.0.0.1]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id E416B17A91 for ; Sat, 23 Mar 2002 13:07:21 +0000 (GMT) X-Received: from lycos.com (unknown [211.250.206.130]) by mercury.hgmp.mrc.ac.uk (Postfix) with SMTP id 7A98417A43 for ; Sat, 23 Mar 2002 13:07:07 +0000 (GMT) X-Received: from unknown (85.125.102.83) by asy100.as122.sol.superonline.com with QMQP; Sat, 23 Mar 2002 18:14:41 -0500 X-Reply-To: X-To: Admin@hgmp.mrc.ac.uk X-Priority: 3 (Normal) X-MSMail-Priority: Normal X-Mailer: Microsoft Outlook Express 5.50.4133.2400 X-Importance: Normal To: p450@hgmp.mrc.ac.uk Sender: owner-p450@hgmp.mrc.ac.uk Precedence: bulk Pertinent Domain Info Dear Internet User: The three new Internet domain extensions: .NAME .BIZ .INFO . have now been officially launched on the Internet. However, many users are still unfamiliar with how these names work. The following are some tips on what these names are and where you can register. ============== NAME Extension ============== - Currently in pre-registration stage. - Designed for personal use. - 2-level domain format (eg. FirstName.LastName.name) - Used for web URL (www.FirstName.Lastname.name) or email (FirstName@LastName.name) - Registry accepts submissions once a week, first come first serve basis. - Where to pre-register: http://www.namesforeveryone.com. ============== BIZ Extension ============== - Currently operational. - Designed for business use. - No registration restrictions. - Works just like a .COM name - Where to register: http://www.dotbiztoday.com ============== INFO Extension ============== - Currently operational. - Designed for information on products / organizations - No registration restrictions - Works just like a .COM name - Where to register: http://www.infograb.com Over one million of the above extensions have already been registered by other users. Therefore, if your name is still available, you should secure it immediately to avoid possible disputes. Yours truly, Domain Administrator International Registry Services 2646taVd3-310xwyt3743WJdF3-659NCFo7689uJps9-702FDGI1212cBYf5-091NQAS5271Zbqdl72 ---