From owner-recombination@net.bio.net Sat Feb 06 22:00:00 1999 Path: biosci!biosci!not-for-mail From: daemon@net.bio.net Newsgroups: bionet.molbio.recombination Subject: Int Symposium Molecular Genetics of Mental Disorders Date: 7 Feb 1999 06:57:01 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 22 Approved: genestructure@yahoo.com Distribution: world Message-ID: <79k9jt$hjf@net.bio.net> NNTP-Posting-Host: net.bio.net International Symposium "Molecular Genetics of Mental Disorders" Date : December 1-3, 1999 Castres (Tarn) France The final scientific program is now available on http://www.entretiens-du-carla.com > > > > == Moderated bionet.genome.gene-structure _________________________________________________________ DO YOU YAHOO!? Get your free @yahoo.com address at http://mail.yahoo.com From owner-recombination@net.bio.net Mon Feb 08 22:00:00 1999 Path: biosci!biosci!not-for-mail From: "SciMedWeb" Newsgroups: bionet.molbio.recombination Subject: SciMedWeb news Date: 9 Feb 1999 01:08:32 -0800 Organization: EUnet Belgium, Leuven, Belgium Lines: 22 Sender: daemon@net.bio.net Approved: genestructure@yahoo.com Distribution: world Message-ID: <79otug$4q0@net.bio.net> NNTP-Posting-Host: net.bio.net Breast cancer metastasis - Molecular aspects: a selection of papers September-October 1998: http://www.geocities.com/HotSprings/Spa/3430/1998_5.htm Breast cancer-gene therapy: a selection of papers 1998: http://www.geocities.com/HotSprings/Spa/3430/bcther98.htm > > > == Moderated bionet.genome.gene-structure _________________________________________________________ DO YOU YAHOO!? Get your free @yahoo.com address at http://mail.yahoo.com From owner-recombination@net.bio.net Fri Feb 12 22:00:00 1999 Path: biosci!biosci!not-for-mail From: "Scott Shanes" Newsgroups: bionet.molbio.recombination Subject: US-NY-IN VIVO IMMUNOLOGY SCIENTIST Date: 13 Feb 1999 03:33:30 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 40 Sender: daemon@net.bio.net Approved: genestructure@yahoo.com Distribution: world Message-ID: <7a3nua$65d@net.bio.net> NNTP-Posting-Host: net.bio.net US-NY-IN VIVO IMMUNOLOGY SCIENTIST I am looking for a Scientist to work in a lab in which they will be involved in setting up and designing in vivo immunology animal models to support drug discovery efforts, as well as, evaluating small molecule inhibitors in these animal models. The candidate will have experience with in vivo / ex vivo immunology with a focus on T-cell biology. Additional experience would include, graft rejection and transplantation models, allergy, psoriasis and autoimmune disease models. Experience working with cytokines and theirreceptors and peripheral blood lymphocytes including mixed lymphocyte reactions would be a plus. The candidate should possess a Ph.D. degree in Immunology. Our client is a leading bio-tech firm with research facilities in Westchester, New York and can provide excellent benefits (health insurance, dental, and vision plan, paid vacation and more). A high impact, high profile position with excellent opportunity for advancement. Please contact Stan Smith by phone at 609-584-8733 Ext. 218, fax CV and cover letter to 609-584-9575 or E-Mail to sis@diedremoire.com. == Moderated bionet.genome.gene-structure _________________________________________________________ DO YOU YAHOO!? Get your free @yahoo.com address at http://mail.yahoo.com From owner-recombination@net.bio.net Fri Feb 12 22:00:00 1999 Path: biosci!biosci!not-for-mail From: BIOSCI Administrator Newsgroups: bionet.molbio.recombination Subject: BIOSCI/bionet miniFAQ & Fundraiser Date: 13 Feb 1999 04:12:56 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 250 Sender: daemon@net.bio.net Approved: genestructure@yahoo.com Distribution: world Message-ID: <7a3q88$7jc@net.bio.net> NNTP-Posting-Host: net.bio.net > > (LAST REVISION: 30-JUL-95) > > This BIOSCI "miniFAQ" is designed to answer the questions that come up > the *most frequently*. The main BIOSCI FAQ (Frequently Asked > Questions) is accessible on the World Wide Web at URL > http://www.bio.net/. > > If you can not find an answer to your question in this or other > documentation, the BIOSCI technical support staff answers e-mail > queries sent to > > biosci-help@net.bio.net > > We can only answer questions about the use of the newsgroups and > mailing lists. We unfortunately do not have the staff to do Internet > information searches or answer scientific questions. Please post > those to the appropriate BIOSCI/bionet newsgroups. > > > Contents: > -------- > 0) BIOSCI NEEDS YOUR SUPPORT!! > > 1) Using the WWW to access the BIOSCI/bionet newsgroups. > > 2) What to do about "spams," i.e., junk mail, ads, etc. > > 3) Examples of subscribing and unsubscribing to the mailing lists. > > 4) The BIOSCI user address and research interest directory. > > > 0) BIOSCI NEEDS YOUR SUPPORT!! > ------------------------------ > BIOSCI's government funding has been expended, and we are now > operating solely from advertising revenue that we have raised from our > Web site at http://www.bio.net/. We need just a few minutes of your > time to help us serve you. > > You can do two important things which will take very little time for > you individually and will immensely help us continue to help you. > > First, please use our WWW system at http://www.bio.net/ to access the > archives. You can post or reply to messages via your Web browser as > described in item #1 below. Your usage helps attract sponsors. If you > contact any of our sponsors, please be sure to thank them for > supporting BIOSCI. It is critical for them to get this feedback if > they are to continue their sponsorship for the long term. > > Second, if you work for a company or organization that provides > products or services of interest to the biology community, please pass > this message on to your marketing or marketing communications > department or other appropriate group. Please ask them to help > support BIOSCI by sponsoring our Web site and explain the uses and > benefits of the system to the biology community. If they are > interested, they can then contact us for further information at our > tech support address, biosci-help@net.bio.net. > > > 1) Using the WWW to access the BIOSCI/bionet newsgroups. > -------------------------------------------------------- > As of 10 December 1995, all BIOSCI/bionet full newsgroups are > accessible through the World Wide Web (WWW) at URL http://www.bio.net. > One can read and reply publicly or privately to both recent postings > and archived messages through one's Web browser if it is configured > properly to send e-mail. Each newsgroup is equipped with its own WAIS > index. The main BIOSCI home page also has access to the BIO-JOURNALS > Table of Contents database WAIS index and the BIOSCI user address > database described in another item further below. > > > 2) What to do about "spams," i.e., junk mail, ads, etc. > ------------------------------------------------------- > BIOSCI is a set of parallel USENET newsgroups (the "bionet" groups), > mailing lists, and a hypermail archive at URL http://www.bio.net/. > The same postings are distributed on all media (except for a small > number of mailing-list-only groups at net.bio.net). Unfortunately it > is becoming a despicable practice on the Internet (by a few people out > to make a fast buck) to do automated mass postings to thousands of > newsgroups and mailing lists. These attempts to grab free advertising > are refered to as "spams" in the usual, somewhat boneheaded, net > terminology. USENET is more susceptible to this practice, and many > spams originate on the USENET groups and then are passed on to the > mailing lists. However, spammers also get lists of mailing addresses > and hit these too, so neither medium is immune. > > What should you do personally if you get junk mail? > --------------------------------------------------- > Just delete it and move on without reading it further. Filing a > protest is becoming increasingly useless because spammers are often > disguising the addresses where the messages are sent from. Unless you > really understand Internet mail systems, your attempt at protest by > sending replies to the message will often end up being sent to the > address of an innocent person that the spammer is victimizing. > > What can BIOSCI/bionet do to protect its newsgroups? > ---------------------------------------------------- > The only solution currently available is to moderate the newsgroup. > If this newsgroup is already moderated, then you are in good shape. > Moderation protects the USENET distribution from about 95% of the > spams that are being sent to date and protects the mailing lists > completely. Moderation means, however, that someone has to take the > time to review each message before it goes out. We have set up > software here that simply allows the moderator to forward to an > address at net.bio.net messages that (s)he wishes to have distributed. > This takes no more time than that needed to read the message and pass > it on, say about 1 min. per message. > > Most newsgroups currently have a discussion leader who is responsible > for their newsgroup. The discussions leaders and their e-mail > addresses are listed in the BIOSCI Information Sheet which is > available on the Web at http://www.bio.net/. If a newsgroup is being > hit with too many junk postings, please contact the discussion leader > for that group and see if there is interest in moderating the group. > Please do not assume that by simply posting a complaint to the > newsgroup itself, anyone on the BIOSCI staff will act on your > complaint. With close to 100 newsgroups to run, the BIOSCI staff has > to rely on the discussion leaders of each newsgroup to report problems > directly to us at biosci-help@net.bio.net. > > We will moderate any of our newsgroups if the discussion leader tells > us that the readership of the group wishes to do so and if a moderator > is willing to do the work. For most BIOSCI/bionet groups, this > entails only a few minutes of work each day. > > Moderating a newsgroup will resolve probably 95% of the junk postings > on the USENET distribution. Unfortunately there are easy ways for > determined spammers to override the moderation mechanism on USENET, > but we can protect our e-mail subscribers from unwanted postings if > the newsgroup is moderated. You can also access our newsgroups over > the WWW at URL http://www.bio.net. While this Web interface will not > stop spammers from trying to post to the groups, this will give you > yet another way, besides using USENET news, to keep the junk out of > your personal mail files. For those of you with local USENET news > systems, the Web interface will also give you faster access to new > newsgroups and recent postings. > > > 3) Examples of subscribing and unsubscribing to the mailing lists. > ------------------------------------------------------------------ > PLEASE NOTE: The BIOSCI management does NOT act on > subscription/unsubscription requests that are posted improperly to the > newsgroups and mailing lists. People who do this only bother everyone > on the lists to no avail. Please be sure to follow the proper > procedures below. > > Gory details are in the BIOSCI Information sheets on the Web at > http://www.bio.net. Below we give an example utilizing the > METHODS-AND-REAGENTS list at both of our two BIOSCI sites: > > Users in the Americas and Pacific Rim countries who use the BIOSCI > ------------------------------------------------------------------ > node at computer net.bio.net: > ---------------------------- > > A) Determine the "listname" which is the <=8 character mail address > ^^^^^^^^^^^^^ > for the group. These can be found in the BIOSCI Info. Sheet. For > the METHODS-AND-REAGENTS group the mailing address is > methods@net.bio.net. The listname is the portion of the address to > the left of the @ sign, i.e., "methods". The listname is used with > the "subscribe" and "unsubscribe" commands illustrated below. > > B) Mail all commands in the body of a mail message addressed to > biosci-server@net.bio.net. Do NOT send commands to the newsgroup > posting addresses! Leave the Subject: line blank, any text on it > will be ignored. > > C) In the body of your message put one or more of the following > commands with an "end" command on the last line, e.g., > > subscribe methods > unsubscribe methods > end > > Do NOT put your e-mail address or other text on these lines. The > server only allows you to cancel your subscription if the address > on your mail header matches the address on our mailing list. > Please ask for help at biosci-help@net.bio.net if your address has > changed, e.g., if you know you are on the list but the server tells > you that you are not a member. > > > Users in Europe, Africa, and Central Asia who use the BIOSCI node at > -------------------------------------------------------------------- > computer daresbury.ac.uk (also known as dl.ac.uk): > ------------------------------------------------- > > To subscribe and unsubscribe to/from the BIOSCI lists, you need to > specify the full USENET newsgroup name with "bionet-news." prepended. > The USENET newsgroup names are listed in the BIOSCI Information sheet > on the Web at http://www.bio.net/. For the METHODS-AND-REAGENTS list > the USENET newsgroup name is bionet.molbio.methds-reagnts, thus the > appropriate commands are > > sub bionet-news.bionet.molbio.methds-reagnts > > unsub bionet-news.bionet.molbio.methds-reagnts > > These commands are included in a message addressed to mxt@dl.ac.uk, > NOT to the newsgroup mailing addresses. As usual, include the text in > the body of the message as text on the Subject: line is ignored. > > To unsubscribe from all the lists at the UK node, use > > unsub bionet-news > > Please note that if the address in the list is different than the one > in your mail message header, you will not be able to unsubscribe by > this method. If you have problems, please mail biosci@daresbury.ac.uk. > > > 4) The BIOSCI user address and research interest directory. > ----------------------------------------------------------- > Please take this opportunity to add your name, address, and research > interest information to the BIOSCI User Address Database if you have > not already done so. > > You can fill out the address form directly through our Web page at URL > http://www.bio.net/adrform.html. > > The address database is reindexed nightly for WWW access (the URL is > http://www.bio.net/). If you are not directly on the Internet but can > reach it by e-mail, please use our waismail server to access the user > directory. waismail use is described above. You can also request a > user address form by e-mail from biosci-help@net.bio.net. > > Please check your database entry from time-to-time to see if your > address information is still up-to-date. Because of our limited > personnel resources, we ask that you resubmit a *complete* form to > revise your entry; we only replace complete entries and do not have > resources to edit old forms. > > == Moderated bionet.genome.gene-structure _________________________________________________________ DO YOU YAHOO!? Get your free @yahoo.com address at http://mail.yahoo.com From owner-recombination@net.bio.net Sat Feb 13 22:00:00 1999 Path: biosci!biosci!not-for-mail From: "G. Dellaire" Newsgroups: bionet.molbio.recombination Subject: Bioinformatics session in TMBM'99 conference Date: 14 Feb 1999 08:21:37 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 842 Sender: daemon@net.bio.net Approved: genestructure@yahoo.com Distribution: world Message-ID: <7a6t6h$c0d@net.bio.net> NNTP-Posting-Host: net.bio.net Dear Colleague, There is a big international conference in the Netherlands from 30 une to 3 July on "Theory and Mathematics in Biology and Medicine". It includes a session on 'Sequencing, folding, and molecular stucture' (ets say: bioinformatics), which focuses on theoretical and mthematical aspects of bioinformatics. We, as session organisers, would like to point out to you that the deadline for abstracts is 1 March 1999. If you wish to take part in this exciting conference, took a look at the website http://www.bio.vu.nl/tmbm99 for further details or read the conference announcement and call for abstracts that we have included in this messages. We hope to see you there as presenter or participant! The session organisers "Sequencing, Folding, and Molecular Structure" F.H.D. van Batenburg (University of Leiden, The Netherlands) J.J.M. Riethoven (European Bioinformatics Institute, UK) -------------------------------------- SECOND AND FINAL ANNOUNCEMENT > > > Theory and Mathematics in Biology and Medicine > > > June 29 - July 3, 1999 > Vrije Universiteit Amsterdam, The Netherlands > > > > >A meeting organised under auspices of: > >- The European Society for Mathematical and Theoretical Biology (ESMTB) > >- The Society for Mathematical Biology (SMB) > >- The Netherlands Society for Theoretical Biology (NVTB) > > > > > >------------------------------------------------------------------------ > >------ > >WELCOME > > > >The international conference on Theory and Mathematics in Biology and > >Medicine 1999 will be held in Amsterdam, the Netherlands from Tuesday > >June > >29 through Saturday July 3, 1999. The organising committee is pleased > to > >invite colleagues all over the world to join this conference. > > > >Theoretical and mathematical biology and medicine is a diverse field in > >which interdisciplinary collaboration is essential for progress. The > >field > >ranges from experimental research linked to mathematical modelling to > >the > >development of more abstract mathematical frameworks in which > >observations > >about the real world can be interpreted and with which new hypotheses > >for > >testing can be generated. More recently, much attention is also paid to > >the > >development of efficient algorithms for complex computations and > >visualisation, notably in molecular biology and genetics (i.e. genome > >mapping). > > > >The TMBM99 conference aims to stimulate interdisciplinary collaboration > >between mathematicians and the bioscientists and to act as the main > >forum > >for the exchange of recent research results and new research directions > >to > >the widest possible community in theoretical biology and medicine. The > >meeting is unique in that it is the fourth official tri-annual congress > >of > >the European Society for Mathematical and Theoretical Biology (ESMTB) > >joined with the annual conference of the Society for Mathematical > >Biology > >(SMB) for 1999. The conference is organised by the Netherlands Society > >for > >Theoretical Biology, the world's oldest society for theoretical > >biology. Through these links, this will be the first World Congress > >devoted > >to one of the fastest growing domains in science where experimental > >biology > >and medicine, biochemistry, mathematics, computational science, physics > >and > >various fields of technology come together to attack many problems of > >great > >relevance to society. > > > >In this second and final announcement you will find information about > >the scientific program and about the possibilities to present oral and > >poster contributions. In addition we provide some information on > >registration and submission of abstracts and we guide you to our web > >page for actual registration and submission. > > > >We are looking forward to see you at the conference. > > > >The organising committee > > > >------------------------------------------------------------------------ > >------ > >ORGANISATION > > > >Organising committee: > >Andre de Roos, Frank van den Bosch, Paul Doucet, Odo Diekmann, Patsy > >Haccou, Hans Heesterbeek, Lia Hemerik, Jaap Kaandorp, Carolien de > >Kovel, Mirjam Kretzschmar, Bob Kooi, Matthijs Luger, Jaap van Pelt, > >Hans Westerhoff. > > > > > >Scientific committee: > >Zvia Agur, Wolfgang Alt, Albert Goldbeter, Lou Gross, Mats Gyllenberg, > >Reinhart Heinrich, Andreas Herz, Paulien Hogeweg, Yoh Iwasa, Vlastimil > >Krivan, Yuri Kuznetsov, Alan Perlson, Andrea Pugliese, Chris Sander, > >Angela Stevens. > > > >Sponsors: > >As of December 1998, the conference is financially supported by: > >The Society of Mathematical Biology (SMB), and > >The Netherlands Organisation for Scientific Research (NWO) > > > >------------------------------------------------------------------------ > >------ > >SCIENTIFIC PROGRAM > > > >The scientific program is organised on the basis of a subdivision into > >specific subjects. Oral and poster contributions by participants are > >possible. > > > >There will be several parallel sessions each day. Three different > >types of sessions are planned: > > > >(i) Day sessions: > >These sessions cover an entire day. They include two invited speakers > >in the morning and shorter contributions (15 min.) during the rest of > >the day. > > > >(ii) Afternoon sessions: > >These sessions consist exclusively of a series of shorter > >contributions (15 min.). > > > >(iii) Poster sessions: > >Poster sessions will be organised in the central hall of the Vrije > >Universiteit. During the afternoon there will be time to visit the > >poster sessions and discuss the research presented with the author. > > > >------------------------------------------------------------------------ > >------ > >INVITED SPEAKERS > > > >A number of speakers have been invited to give plenary presentations > >at the conference. The majority of the invited speakers are scheduled > >in sessions with a particular topic. Below you will find a list of > >these sessions with the invited speakers and some information about > >the session contents. > > > >Besides the invited speakers within these sessions the organising > >committee has invited six additional, plenary speakers. > > > >- Prof. Karl P. Hadeler (Tuebingen University, Germany): > >Competition, Variability, and Exclusion: Elimination of some and > >survival for many. > > > >- Prof. Dr. Bruce R. Levin (Emory University, USA): > >Mathematical models of the within and between host population biology > >of antibiotic treatment and resistance > > > >- Prof. Dr. Lila Kari (The University of Western Ontario, Canada): > >DNA computing in vitro and in vivo > > > >- Prof. Dr. Karl Sigmund (University of Vienna, Austria): > >Reciprocal altruism, direct and indirect > > > >- Prof. Dr. Bela Novak (Technical University Budapest, Hungary): > >Modelling the cell division cycle > > > >- Prof. Dr. Eshel Ben-Jacob (Tel-Aviv University, Israel): > >Bacterial wisdom and the challenge of antibiotic resistance > > > > > >- The closing lecture of the conference will be a distinguished lecture > >by > >the first Okubo Prize laureate. This prize is an initiative of the > >Society > >of Mathematical Biology, together with colleagues in Japan to honor the > >memory of Professor Okubo. > > > >------------------------------------------------------------------------ > >------ > >DAY SESSIONS > > > >1. Non-Linear Population Dynamics > >--------------------------------- > >Organisers: > >M. Kirkilonis (Utrecht University, The Netherlands) > >M.P. Boer (Centre for Biometry Wageningen (DLO), The Netherlands) > > > >Invited speakers: > >1. D. Rand (University of Warwick, United Kingdom)) > >2. H.L. Smith (Arizona State University, USA) > > > >Abstract: > >Mathematical population dynamics is one of the oldest disciplines of > >theoretical biology, and has become a major subject in the study of > >ecological and other related problems. Different biological situations > >are described by a wide range of models, mathematically formulated as > >non-linear dynamical systems. Solutions of such systems show a rich > >variety of behaviour hinting at the possible complexity of biological > >interaction between individuals, populations and their environment. > > > > > > > >2. Epidemiology of Infectious Diseases > >-------------------------------------- > >Organisers: > >M. Kretzschmar (National Institute of Public Health and the > >Environment (RIVM), The Netherlands) > >J.A.P. Heesterbeek (Centre for Biometry Wageningen (DLO), The > >Netherlands) > > > >Invited speakers: > >1. R.M. Anderson (University of Oxford, United Kingdom) > >2. K. Dietz (Tuebingen University, Germany) > > > >Abstract: > >This session focuses on the mathematical modelling of the spread of > >infectious diseases in human and animal populations. In particular, we > >invite talks dealing with the effects of contact patterns, stochastic > >phenomena, multiple hosts and evolutionary aspects of infectious > >diseases. > > > > > > > >3. Sequencing, Folding and Molecular Structure > >---------------------------------------------- > >Organisers: > >J.J.M. Riethoven (European Bioinformatics Institute, United Kingdom) > >F.H.D. van Batenburg (Leiden University, the Netherlands) > > > >Invited speakers: > >1. M.S. Waterman (University of Southern California, USA) > >2. P.G. Higgs (University of Manchester, United Kingdom) > > > >Abstract: > >Focusing on the more theoretical and mathematical issues and advances > >in this exciting field of bioinformatics, this one-day session will > >include topics on DNA fragment assembly, sequence/protein comparison, > >sequence analysis, secondary and tertiary structure (prediction) of > >macro- molecules such as RNA, DNA and proteins, sequence analysis, and > >gene prediction. > > > > > > > >4. Evolution, Game Theory and Adaptive Dynamics > >----------------------------------------------- > >Organisers: > >F.J.Weissing (Groningen University, The Netherlands) > >C.G.F. de Kovel (Utrecht University, The Netherlands) > > > >Invited speakers: > >1. J.A.J. Metz (Leiden University, the Netherlands) > >2. (To Be Confirmed) S.C. Stearns (University of Basel, Switzerland.) > > > >Abstract: > >The last three decades have revolutionized the way we think about > >evolution at various levels of organisation. New theoretical ideas on > >topics as molecular evolution, genetic conflicts, frequency- and > >density-dependent selection, sexual selection, spatial interactions, > >or non-equilibrium dynamics have played a major role in this > >process. Still there are major challenges as, for example, the > >integration of genetic and phenotypic approaches to natural selection, > >or the incorporation of developmental genetics into evolutionary > >theory. Several of these topics will be addressed in this session. We > >will also consider the empirical relevance of present-day models and > >discuss whether new modelling approaches are required to improve the > >testability of evolutionary theories. > > > > > > > >5. Computational Neuroscience > >----------------------------- > >Organisers: > >J. van Pelt (Netherlands Institute for Brain Research, The Netherlands) > >A. van Ooyen (Netherlands Institute for Brain Research, The > Netherlands) > > > >Invited speakers: > >1. D. Willshaw (University of Edinburgh, United Kingdom) > >2. (To Be Confirmed) T. Sejnowski (The Salk Institute for Biological > >Studies,USA) > > > >Abstract: > >Understanding the brain in health and disease is perhaps the greatest > >challenge for science in the next century. Because the brain is an > >extremely complex and organised system from the molecular up to the > >behavioural level, this goal can not be achieved without modelling and > >computational approaches. This Session aims at emphasizing this role > >of Mathematical Modelling and Computer Simulation in > >Neuroscience. Participants are invited to present progress in > >understanding the structure, function and development the brain. > > > > > > > >6. Immunology and Within-Host Dynamics of Pathogens > >--------------------------------------------------- > >Organisers: > >R. Mehr (Princeton University, USA) > >R.J. de Boer (University of Utrecht,The Netherlands) > > > >Invited speakers: > >1. L.A. Segel (The Weizmann Institute of Science, Israel) > >2. T.B. Kepler (North Carolina State University, USA) > > > >Abstract: > >The immune system is a typical example of a complex system having many > >feedback interactions. Our intuition for understanding the functioning > >of the immune system is therefore be markedly sharpened by studying > >mathematical models. These models involve regulatory networks, > >competition, and evolution. Recent mathematical work on the > >within-host dynamics of viruses like HIV, HBV, and HCV have had great > >impact on our understanding of such infections. > > > > > >------------------------------------------------------------------------ > >------ > >AFTERNOON SESSIONS > > > >1. Individual-Based Population Dynamics > >--------------------------------------- > >Organiser: > >S.A.L.M. Kooijman (Vrije Universiteit, The Netherlands) > > > >Abstract: > >We like to welcome contributions that highlight > >- problems that relate individual dynamics to population performance > >- mass and energy conservation at the population level > >- relationships between structured and unstructured population dynamics > > (effects of aggregation, simplification) > >- analyze structured population dynamics in terms of bifurcation > > analysis and transient behaviour > >- interactions between (structured) populations (food chains, food > webs) > > > > > > > >2. Gene Networks > >---------------- > >Organisers: > >D. Thieffry (University of Brussels, Belgium) > >L. Glass (McGill University, Canada) > > > >Abstract: > >Structure and Dynamics of Gene Networks: As molecular data about > >specific regulatory mechanisms of gene expression are rapidly > >accumulating, there is an increasing need for integrative and formal > >tools. This session aims to review the different theoretical > >approaches dealing with the dynamical analysis of gene networks. It > >will cover the analysis of specific functional modules, as well as > >methodologies addressing gene networks at the level of whole > >organisms. It will encompass some of the tools to derive the dynamical > >behaviour resulting from specific network structures, but also > >attempts to infer regulatory architectures from temporal and/or > >spatial data of gene expression. > > > > > > > >3. Pattern Formation and Morphogenesis > >-------------------------------------- > >Organiser: > >P.K. Maini (University of Oxford, United Kingdom) > > > >Abstract: > >Recently, many advances have been made in understanding pattern > >formation in certain chemical and biological systems, and in the > >derivation of macroscopic models from observations at the microscopic > >level. This session will focus on the modelling and analysis of > >pattern formation in these areas. > > > > > > > >4. Education in Mathematical Biology > >------------------------------------ > >Organiser: > >J.R. Jungck (Beloit College, USA) > > > >Abstract: > >Not available > > > > > > > >5. Parasites and Diseases in Wildlife > >------------------------------------- > >Organiser: > >A. Pugliese (University of Trento, Italy) > > > >Abstract: > >This session aims at developing a common thread through different > >biological systems (micro- and macro-parasites; single or multi-host) > >and different modelling approaches. Topics will range from parasite > >interactions within hosts, through classical host-parasite systems, up > >to parasites' effect on communities. > > > > > > > >6. Metabolic Control Networks > >----------------------------- > >Organiser: > >H. Westerhoff (University of Amsterdam, The Netherlands) > > > >Abstract: > >The living cell is one of the most complex objects studied by the > >natural sciences and mathematics. To a great extent this complexity > >derives the great many processes that occur in parallel, in a highly > >coordinated manner. Most of these processes lead to steady states, but > >others give rise to stationary oscillations, or even more complex > >patterns in space and time. The networks that are responsible for > >these dynamic processes, are structurally adaptable, as in a neural > >network. Intracellular 'compartments' are crowded with > >macromolecules. As a consequence of all this, functional processes of > >living cells are not controlled by a single 'rate-limiting' step in > >the corresponding metabolic pathway. Rather, control tends to be > >distributed over various levels of intracellular organisation, > >including metabolism, signal transduction, gene expression, and time, > >reflecting adaptation of the cell to earlier challenges. Only > >intensive mathematical modelling in conjunction with experiments > >entering the living cell, can make the living cell, and therewith the > >essence of life, understood. It will be the challenge of the next > >century to intensify the application of mathematics to cellular > >biochemistry. In this symposium, the most recent developments in > >theory and biomathematics concerning the living cell as a complex > >object, will be highlighted. > > > > > > > >7. Whole Heart Modelling > >------------------------ > >Organiser: > >S.A. Panfilov (University of Utrecht, the Netherlands) > > > >Abstract: > >This section will be devoted to major problems of mathematical > modelling > >in > >cardiac electrophysiology. We are planing to discuss questions related > >to > >development of anatomically accurate models of the heart and human > torso > >and questions on the best models for cardiac tissue. We also encourage > >participation of researchers interested in mechanisms of cardiac > >arrhythmias and in development of new methods for fighting these > >diseases. > > > > > > > >8. Metapopulation Dynamics > >-------------------------- > >Organiser: > >J. Verboom (Institute for Forestry and Nature Research (IBN-DLO), The > >Netherlands) > > > >Abstract: > >Metapopulation models have been derived and analyzed for gaining > >insight into the dynamics of fragmented populations. The issue is > >still of interest, because of the ongoing destruction and > >fragmentation of habitat, and the hypothetical extinction vortex that > >may lead to extinction of many plant and animal species worldwide > >(also referred to as the extinction debt). > > > > > > > >9. Toxicology > >------------- > >Organisers: > >J.I. Freijer (National Institute of Public Health and the > >Environment (RIVM), The Netherlands) > >M.J. Zeilmaker (National Institute of Public Health and the > >Environment (RIVM), The Netherlands) > > > >Abstract: > >This session on Toxicology focuses on the development of models of the > >toxic working mechanism of chemicals and radiation. The main emphasis > >is on the translation of model concepts into mathematical/computer > >models and the parameterisation and application of the latter. > > > > > > > >10. Particle Based Modelling > >---------------------------- > >Organiser: > >J. Kaandorp (University of Amsterdam, the Netherlands) > >A.M. de Roos (University of Amsterdam, The Netherlands) > > > >Abstract: > >Particle based techniques (for example cellular automata,lattice > >gases, lattice Boltzmann method) are being applied in biological > >models at the molecular, complex, cel, individual, population and > >ecosystem level. This session will focus on the application and > >analysis of models that use any of these methods. > > > > > > > >11. Networks, Cellular Signalling and Biological Rhythms > >------------------------------------------------------- > >Organiser: > >R. Heinrich (Humboldt-University Berlin, Germany) > > > >Abstract: > >This session focuses on the theoretical elucidation of the regulatory > >and dynamical properties of metabolic networks and of pathways of > >extracellular and intracellular signalling, as based on their > >stoichiometric and kinetic properties. Mathematical models concerning > >the whole variety of cellular mechanisms for energy transfer, > >phosphoryl transfer etc., for the action of different messengers, and > >for signalling via cell surface receptors or gap junctions are invited > >for presentation. Different modes of dynamic behaviour, such as > >amplification, oscillations, synchronization, transitions and > >multistationarity will be of interest. Attention is payed to the > >confrontation with experimental data. Besides the results of > >simulating specific systems new methods for the modelling of these > >types of nonlinear dynamic systems may be presented. > > > > > > > >12. Classification Methodology > >------------------------------ > >Organiser: > >(To be confirmed) T. Koski (Royal Institute of Technology, Sweden) > > > >Abstract: > >Important classification problems in biology and medicine include > >taxonomy > >and clinical diagnostics. The recent availability of DNA sequence data > >has > >had a great impact on the mathematical research in taxonomy and this is > >a > >field in rapid progress. This session will focus on recent developments > >and > >new approaches. > > > > > >13. Miscellaneous > >----------------- > >Abstract: > >There will certainly be scientists willing to present interesting work > >at the conference that do not fit into one of the above sessions. The > >organising committee will evaluate the abstract submitted in this > >category separately and if possible organise a suitable way to include > >the presentations in the conference program. > > > > > >------------------------------------------------------------------------ > >------ > >OTHER PROGRAM PARTS > > > >On Tuesday June 29, the organising committee invites the conference > >participants to a welcoming reception. This reception will be held at > >the > >Vrije Universiteit. The reception does not include dinner. > > > >On Wednesday June 30, the annual meeting of the ESMTB will be held. > This > >meeting will take place in the evening at the Vrije Universiteit. > > > >On Thursday July 1, the conference dinner will take place in the > >historic > >city of Volendam. Participants will enjoy fine food in the Spaanders > >Restaurant. > > > > > >------------------------------------------------------------------------ > >------ > >REGISTRATION > > > >Registration fees include admission to all sessions, a program and > >abstract book, coffee, tea and admission to the welcoming reception. > > > >Registration is possible through our web-site. You can find the > >instructions on the following web-site: http://www.bio.vu.nl/tmbm99 > > > >Registration in advance is recommended. On site registration is > strongly > >discouraged but possible. > > > >The registration desk will be located on the ground floor of the Main > >building of the Vrije Universiteit. It will be open on: > > > > Tuesday June 29, 1999 from 10.00-18.00 > > Wednesday June 30, 1999 from 08.00-18.00 > > Thursday July 1, 1999 from 08.30-18.00 > > Friday July 2, 1999 from 08.30-18.00 > > Saturday July 3, 1999 from 08.30-12.00 > > > > > >Registration fee > >---------------- > >Early registration (before April 1, 1999) > >1) ESMTB or SMB member* (NLG 275,-) > >2) Non member (NLG 350,-) > >3) Student** (NLG 150,-) > > > >Late registration (after April 1, 1999) > >1) ESMTB or SMB member* (NLG 375,-) > >2) Non member (NLG 450,-) > >3) Student** (NLG 250,-) > > > >* Membership will be checked against membership lists provided by > ESMTB > >and > > SMB. Note that the ESMTB requires members to pay their 1999 > > contribution before January 31, 1999, to qualify for the reduced > > registration fee. > >** Student fee applicable only if a photocopy of the student > >registration card > > is sent to the University Conference Service, De Boelelaan 1105, > > NL-1081 HV Amsterdam, The Netherlands. > > > > > >Other costs > >----------- > >The Amsterdam City Council has a discouragement policy concerning the > >use > >of cars in the city center. Therefore there is very limited free > parking > >in > >the city. Since Amsterdam has a dense public transport network, > >including > >bus, tram and subway, participants are strongly advised to take > >advantage > >of it. You can book a 5-day "go as you please ticket" (NLG 27,-) on > the > >registration form. > > > >Attending the conference dinner will be an additional NLG 75,- > > > >The registration form on our web-site (http://www.bio.vu.nl/tmbm99) > >gives > >you options for booking the public transport ticket or tickets for > >attending the conference dinner. > > > > > >Payment > >------- > >You can pay by cheque, bank remittance and credit card. Registration > >will > >not be valid until the required fee has been received. All payments > must > >be > >in Dutch currency (NLG). Participants' registration will not be > >confirmed > >until receipt of the registration fee. > > > > > >Cancellation > >------------ > >In case of cancellation the total fee minus the handling charges (NLG > >80,-) will be refunded, provided a written request is received by the > >VU Conference Service before June 1 1999. > > > >Please visit the web-site http://www.bio.vu.nl/tmbm99 for more details > >and actual registration. > > > >------------------------------------------------------------------------ > >------ > >CALL FOR ABSTRACTS > > > >We invite all participants to submit an abstract for an oral > >presentation or for a poster. Abstracts will be reviewed by the session > >organiser(s) and by a responsible member of the scientific committee. > > > >A PARTICIPANT CAN ONLY SUBMIT 1 ABSTRACT AS FIRST AUTHOR. If a > >participant sends in more than a single abstract we will only take the > >first one submitted into consideration. > > > >The abstract submission deadline is March 1, 1999. > > > >Oral presentations: These are 15 minutes presentations (plus 5 minutes > > discussion). You can indicate in which session > > your presentation fits best. The first author has > > to give the presentation at the conference. > > > >Poster presentation: Posters will be displayed for one day. You are > >required > > to be present at the poster viewing time for > > discussions with other participants. > > > >Please visit the web-site http://www.bio.vu.nl/tmbm99 for more details > >and submission of an abstract. > > > >------------------------------------------------------------------------ > >------ > >HOTEL ACCOMMODATION > > > >Preliminary reservations of rooms have been made in a range of hotels > >within the city of Amsterdam. Hotels in different categories are > >available > >for booking. > > > >Hotel reservations will be handled by: > > > >Carlson Wagonlit Travel > >Dam 19 > >1012 JS Amsterdam, The Netherlands > >Phone# +31-(0)20-6241361 > >Fax# +31-(0)20-6235107 > >e-mail: agm@keytours.nl > > > > > >Cancellation > >------------ > >In case of cancellation the total amount minus handling charges (NLG > >50,-) will be refunded, provided a written request is received by > >Carlson Wagonlit Travel before June 21 1999. > > > >Visit our web-site http://www.bio.vu.nl/tmbm99 for a list of hotels > >and booking of accommodation. > > > > > >------------------------------------------------------------------------ > >------ > >IMPORTANT DATES > > > >March 1, 1999: abstract submission deadline > > > >April 1, 1999: early registration deadline > > > >May 15, 1999: notification of acceptance of abstract > > > >June 1, 1999: deadline of cancellation with partial reimbursement > > > >June 21, 1999: deadline of hotel cancellation with partial > reimbursement > > > > > >------------------------------------------------------------------------ > >------ > >IMPORTANT ADDRESSES > > > >- For the most complete source of the latest information: > > > >The conference web-site http://www.bio.vu.nl/tmbm99 > > > > > >- For answers to some Frequently Asked Questions: > > > >http://toranaga.bio.uva.nl/~aroos/tmbm99-faq.html > > > > > >- For information concerning registration, abstract forms, etc.: > > > >University Conference Service > >De Boelelaan 1105 > >NL-1081 HV Amsterdam, The Netherlands > >Phone# +31-(0)20-444 5790 > >Fax# +31-(0)20-444 5825 > >e-mail: vu_conference@dienst.vu.nl > > > > > >- For hotel reservation: > > > >Carlson Wagonlit Travel > >Dam 19 > >1012 JS Amsterdam, The Netherlands > >Phone# +31-(0)20-6241361 > >Fax# +31-(0)20-6235107 > >e-mail: agm@keytours.nl > > > > > >-For contacting the organising committee: > > > >e-mail: tmbm99@bio.vu.nl > > > == Moderated bionet.genome.gene-structure _________________________________________________________ DO YOU YAHOO!? Get your free @yahoo.com address at http://mail.yahoo.com From owner-recombination@net.bio.net Sun Feb 21 22:00:00 1999 Path: biosci!biosci!not-for-mail From: Michael Sherrell Newsgroups: bionet.molbio.recombination Subject: ABI 377 for sale Date: 22 Feb 1999 12:00:32 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 59 Sender: daemon@net.bio.net Approved: genestructure@yahoo.com Distribution: world Message-ID: <7asd10$gsj@net.bio.net> NNTP-Posting-Host: net.bio.net > Newly for sale: > ABI 377 DNA sequencer, XL, 96 lanes, under transferrable Perkin Elmer service contract until March 2000. Price: $105,000. > > I also have these peptide and oligo synthesizers and sequencers, LC-mass specs and NMRs for sale: > > Synthesizers and sequencers: > ABI 394 synthesizer, valve blocks rebuilt, warranteed: $12,500          > ABI Procise 492 protein sequencer, $59,000 > ABI 3948 synthesizer: inquire > ABI 390Z synthesizer, 50-100uM yields: $4,000        > ABI 373 stretch, 5-filter, Genescan, under ABI service: $19,500 > Li-Cor 4000LS, 1994 model: <$20,000 > ABI 430, working: $6,000 > ABI 430, rebuilt, warranteed: $10,500 > ABI 433, upgraded by ABI from 431: $39,000 > Advanced ChemTech 396 Multiple Biomolecule Synthesizer, unused: $45,000 > PerSeptive 9050+, $6,000 > + a variety of other ABI, PerSeptive, HP, Biosearch, ACT, etc. synthesizers and sequencers > > LC-MS: > PE Sciex API III+, 5yrs old, ES, APCI (installation available): $82,000 > Finnigan TSQ 7000, installed, warranty: $149,000      > Finnigan TSQ 700, 1995; NOT Y2K compliant; under Finnigan service now: $80,000 > HP 5989B, extended mass range (2000 amu), hex ion guide (HPLC, installation & warranty available): $45,000 > > NMRs: > Bruker AMX-500, installed: $175,000 > Bruker AC-250, running in lab now: $30,000 > Varian Gemini 300: $70,000 > . > Please contact me to discuss any of these, or if you have any items you might like to sell. > > Michael Sherrell > Grizzly Analytical > 707 887 2919/fax 707 887 9834 > www.grizzlyanalytical.com > == Moderated bionet.genome.gene-structure _________________________________________________________ DO YOU YAHOO!? Get your free @yahoo.com address at http://mail.yahoo.com From owner-recombination@net.bio.net Thu Feb 25 22:00:00 1999 Path: biosci!biosci!not-for-mail From: daemon@net.bio.net Newsgroups: bionet.molbio.recombination Subject: Anyone knowledgeable about RecA? Date: 26 Feb 1999 10:26:44 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 54 Approved: genestructure@yahoo.com Distribution: world Message-ID: <7b6p14$4rd@net.bio.net> NNTP-Posting-Host: net.bio.net > > Hello; > > I am a graduate student doing some work on RecA strand exchange > reactions. Unfortunately, my original background is not in biology > (it's in physics) so there are rather a lot of questions I have which > may be trivial background knowledge to somebody with a biology > background. > > I would greatly appreciate any help on some of these questions. > My email address is > > kklap@biomath.medsch.ucla.edu > > Two of my main questions are: > > 1) For a strand exchange reaction in which one of the substrates had a > heterologous insert is completed, is the heterologous region incorporated > into the final product as a loop (a D loop?) of ssDNA? > 2) During recombination events in prokaryotes where foreign DNA is > incorporated into the DNA of the organism, I assume that in the scenario > described above, the backbone of the DNA strand without the heterologous > insert would eventually be broken, and the heterologous region used as a > template for synthesis. This would lead to lengthening of the DNA over > time, with many recombination events. What are the biological implications > of this? (I know of several physical implications). > > Cheers, > > Kevin > > > > == Moderated bionet.genome.gene-structure _________________________________________________________ DO YOU YAHOO!? Get your free @yahoo.com address at http://mail.yahoo.com