From BIOSCI-REQUEST  Mon Jun  9 02:00:04 1997
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Date: Mon, 9 Jun 1997 02:00:02 -0700
From: BIOSCI Administrator <biohelp>
Message-Id: <199706090900.CAA25536@net.bio.net>
To: rna@net.bio.net
Subject: BIOSCI/bionet miniFAQ & Fundraiser

(LAST REVISION: 30-JUL-95)

This BIOSCI "miniFAQ" is designed to answer the questions that come up
the *most frequently*.  The main BIOSCI FAQ (Frequently Asked
Questions) is accessible on the World Wide Web at URL
http://www.bio.net/.

If you can not find an answer to your question in this or other
documentation, the BIOSCI technical support staff answers e-mail
queries sent to

		       biosci-help@net.bio.net

We can only answer questions about the use of the newsgroups and
mailing lists.  We unfortunately do not have the staff to do Internet
information searches or answer scientific questions.  Please post
those to the appropriate BIOSCI/bionet newsgroups.


	Contents:
	--------
	0) BIOSCI NEEDS YOUR SUPPORT!!

	1) Using the WWW to access the BIOSCI/bionet newsgroups.

	2) What to do about "spams," i.e., junk mail, ads, etc.

	3) Examples of subscribing and unsubscribing to the mailing lists.

	4) The BIOSCI user address and research interest directory.


0) BIOSCI NEEDS YOUR SUPPORT!!
------------------------------
BIOSCI's government funding has been expended, and we are now
operating solely from advertising revenue that we have raised from our
Web site at http://www.bio.net/.  We need just a few minutes of your
time to help us serve you.

You can do two important things which will take very little time for
you individually and will immensely help us continue to help you.

First, please use our WWW system at http://www.bio.net/ to access the
archives.  You can post or reply to messages via your Web browser as
described in item #1 below.  Your usage helps attract sponsors. If you
contact any of our sponsors, please be sure to thank them for
supporting BIOSCI. It is critical for them to get this feedback if
they are to continue their sponsorship for the long term.

Second, if you work for a company or organization that provides
products or services of interest to the biology community, please pass
this message on to your marketing or marketing communications
department or other appropriate group.  Please ask them to help
support BIOSCI by sponsoring our Web site and explain the uses and
benefits of the system to the biology community. If they are
interested, they can then contact us for further information at our
tech support address, biosci-help@net.bio.net.


1) Using the WWW to access the BIOSCI/bionet newsgroups.
--------------------------------------------------------
As of 10 December 1995, all BIOSCI/bionet full newsgroups are
accessible through the World Wide Web (WWW) at URL http://www.bio.net.
One can read and reply publicly or privately to both recent postings
and archived messages through one's Web browser if it is configured
properly to send e-mail.  Each newsgroup is equipped with its own WAIS
index.  The main BIOSCI home page also has access to the BIO-JOURNALS
Table of Contents database WAIS index and the BIOSCI user address
database described in another item further below.


2) What to do about "spams," i.e., junk mail, ads, etc.
-------------------------------------------------------
BIOSCI is a set of parallel USENET newsgroups (the "bionet" groups),
mailing lists, and a hypermail archive at URL http://www.bio.net/.
The same postings are distributed on all media (except for a small
number of mailing-list-only groups at net.bio.net).  Unfortunately it
is becoming a despicable practice on the Internet (by a few people out
to make a fast buck) to do automated mass postings to thousands of
newsgroups and mailing lists.  These attempts to grab free advertising
are refered to as "spams" in the usual, somewhat boneheaded, net
terminology.  USENET is more susceptible to this practice, and many
spams originate on the USENET groups and then are passed on to the
mailing lists.  However, spammers also get lists of mailing addresses
and hit these too, so neither medium is immune.

What should you do personally if you get junk mail?
---------------------------------------------------
Just delete it and move on without reading it further.  Filing a
protest is becoming increasingly useless because spammers are often
disguising the addresses where the messages are sent from.  Unless you
really understand Internet mail systems, your attempt at protest by
sending replies to the message will often end up being sent to the
address of an innocent person that the spammer is victimizing.

What can BIOSCI/bionet do to protect its newsgroups?
----------------------------------------------------
The only solution currently available is to moderate the newsgroup.
If this newsgroup is already moderated, then you are in good shape.
Moderation protects the USENET distribution from about 95% of the
spams that are being sent to date and protects the mailing lists
completely.  Moderation means, however, that someone has to take the
time to review each message before it goes out.  We have set up
software here that simply allows the moderator to forward to an
address at net.bio.net messages that (s)he wishes to have distributed.
This takes no more time than that needed to read the message and pass
it on, say about 1 min. per message.

Most newsgroups currently have a discussion leader who is responsible
for their newsgroup.  The discussions leaders and their e-mail
addresses are listed in the BIOSCI Information Sheet which is
available on the Web at http://www.bio.net/.  If a newsgroup is being
hit with too many junk postings, please contact the discussion leader
for that group and see if there is interest in moderating the group.
Please do not assume that by simply posting a complaint to the
newsgroup itself, anyone on the BIOSCI staff will act on your
complaint.  With close to 100 newsgroups to run, the BIOSCI staff has
to rely on the discussion leaders of each newsgroup to report problems
directly to us at biosci-help@net.bio.net.

We will moderate any of our newsgroups if the discussion leader tells
us that the readership of the group wishes to do so and if a moderator
is willing to do the work.  For most BIOSCI/bionet groups, this
entails only a few minutes of work each day.

Moderating a newsgroup will resolve probably 95% of the junk postings
on the USENET distribution.  Unfortunately there are easy ways for
determined spammers to override the moderation mechanism on USENET,
but we can protect our e-mail subscribers from unwanted postings if
the newsgroup is moderated.  You can also access our newsgroups over
the WWW at URL http://www.bio.net.  While this Web interface will not
stop spammers from trying to post to the groups, this will give you
yet another way, besides using USENET news, to keep the junk out of
your personal mail files.  For those of you with local USENET news
systems, the Web interface will also give you faster access to new
newsgroups and recent postings.


3) Examples of subscribing and unsubscribing to the mailing lists.
------------------------------------------------------------------
PLEASE NOTE: The BIOSCI management does NOT act on
subscription/unsubscription requests that are posted improperly to the
newsgroups and mailing lists.  People who do this only bother everyone
on the lists to no avail.  Please be sure to follow the proper
procedures below.

Gory details are in the BIOSCI Information sheets on the Web at
http://www.bio.net.  Below we give an example utilizing the
METHODS-AND-REAGENTS list at both of our two BIOSCI sites:

Users in the Americas and Pacific Rim countries who use the BIOSCI
------------------------------------------------------------------
node at computer net.bio.net:
----------------------------

A) Determine the "listname" which is the <=8 character mail address
                                         ^^^^^^^^^^^^^
   for the group.  These can be found in the BIOSCI Info. Sheet.  For
   the METHODS-AND-REAGENTS group the mailing address is
   methods@net.bio.net.  The listname is the portion of the address to
   the left of the @ sign, i.e., "methods".  The listname is used with
   the "subscribe" and "unsubscribe" commands illustrated below.

B) Mail all commands in the body of a mail message addressed to
   biosci-server@net.bio.net.  Do NOT send commands to the newsgroup
   posting addresses!  Leave the Subject: line blank, any text on it
   will be ignored.

C) In the body of your message put one or more of the following
   commands with an "end" command on the last line, e.g.,

   subscribe methods
   unsubscribe methods
   end

   Do NOT put your e-mail address or other text on these lines.  The
   server only allows you to cancel your subscription if the address
   on your mail header matches the address on our mailing list.
   Please ask for help at biosci-help@net.bio.net if your address has
   changed, e.g., if you know you are on the list but the server tells
   you that you are not a member.


Users in Europe, Africa, and Central Asia who use the BIOSCI node at
--------------------------------------------------------------------
computer daresbury.ac.uk (also known as dl.ac.uk):
-------------------------------------------------

To subscribe and unsubscribe to/from the BIOSCI lists, you need to
specify the full USENET newsgroup name with "bionet-news." prepended.
The USENET newsgroup names are listed in the BIOSCI Information sheet
on the Web at http://www.bio.net/.  For the METHODS-AND-REAGENTS list
the USENET newsgroup name is bionet.molbio.methds-reagnts, thus the
appropriate commands are

    sub bionet-news.bionet.molbio.methds-reagnts

    unsub bionet-news.bionet.molbio.methds-reagnts

These commands are included in a message addressed to mxt@dl.ac.uk,
NOT to the newsgroup mailing addresses.  As usual, include the text in
the body of the message as text on the Subject: line is ignored.

To unsubscribe from all the lists at the UK node, use

    unsub bionet-news

Please note that if the address in the list is different than the one
in your mail message header, you will not be able to unsubscribe by
this method. If you have problems, please mail biosci@daresbury.ac.uk.


4) The BIOSCI user address and research interest directory.
-----------------------------------------------------------
Please take this opportunity to add your name, address, and research
interest information to the BIOSCI User Address Database if you have
not already done so.

You can fill out the address form directly through our Web page at URL
http://www.bio.net/adrform.html.

The address database is reindexed nightly for WWW access (the URL is
http://www.bio.net/).  If you are not directly on the Internet but can
reach it by e-mail, please use our waismail server to access the user
directory.  waismail use is described above.  You can also request a
user address form by e-mail from biosci-help@net.bio.net.

Please check your database entry from time-to-time to see if your
address information is still up-to-date.  Because of our limited
personnel resources, we ask that you resubmit a *complete* form to
revise your entry; we only replace complete entries and do not have
resources to edit old forms.

				Sincerely,

				Dave Kristofferson
				BIOSCI/bionet Manager

				biosci-help@net.bio.net

From BIOSCI-REQUEST  Wed Jun 11 02:13:58 1997
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From: Staff <212@212.net>
To: rna@net.bio.net
Subject: cool pixels
Date: Mon, 09 Jun 1997 17:30:53 EST
Message-ID: 970609173053.1CBDF6E@212.net>
Reply-To: 212@212.net
X-Sender: 212@212.net (Staff at 212.net)
X-Mailer: e-Merge for Windows
Content-Type: TEXT/PLAIN; charset=US-ASCII

Cool site! Interested in a link exchange?

Visit http://www.212.net and check out the
most complete free list of search engines
on the net. Over 500 engines and indices
conveniently arranged for your submit and
search needs. And of course pulp & pixels.

          http://www.212.net

        Nice, neat and hard to beat!

Best regards,
staff at 212.net

..................................................
hate this kind of mail? visit http://deleteme.com
..................................................


From BIOSCI-REQUEST  Fri Jun 13 14:13:56 1997
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Date: Fri, 13 Jun 1997 16:25:39 -0400 (EDT)
From: Marcela Madrid <mm6n+@andrew.cmu.edu>
To: rna@net.bio.net
Subject: PSC Sequence Analysis Workshop announcement incorrect
Cc: editor@newsmaster.tgc.com, chemistry@osc.edu

The registration date for the workshop is June 20, not July 20. Please
correct this before you post the announcement. Thank you 

From BIOSCI-REQUEST  Fri Jun 13 17:13:08 1997
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Date: Fri, 13 Jun 1997 15:24:18 -0400 (EDT)
From: Marcela Madrid <mm6n+@andrew.cmu.edu>
To: rna@net.bio.net
Subject: PSC Sequence Analysis Workshop

The Pittsburgh Supercomputing Center is offering a
NUCLEIC ACID AND PROTEIN SEQUENCE ANALYSIS
workshop, July 20-25, 1997.

This intense workshop will teach the basics of sequence analysis, including
remote supercomputing, database searching and pairwise sequence alignment,
multiple sequence alignments, pattern identification, inverse structure
prediction, and visualization of macromolecular structures. Special
emphasis will be placed on parameter selection, and the mathematical and
statistical properties of the algorithms and methods presented.
Information will also be presented on the latest pattern identification
techniquesincluding hidden markov models, advanced position-specific
weight matrix techniques and bayesan estimation.

The workshop will consist of both lectures and extensive hands-on lab sessions.

In addition to the lab exercises, participants can work on their own research
problems, with the help of the instructors.  Participants are encouraged to
bring their research data, but not required.

Instructors
Dr. Gary Churchill, Cornell University
Dr. David W. Deerfield II, Pittsburgh Supercomputing Center
Dr. Michael Gribskov, San Diego Supercomputer Center
Dr. Hugh B. Nicholas Jr., Pittsburgh Supercomputing Center
Alexander J. Ropelewski, Pittsburgh Supercomputing Center

For more information, please see
http://www.psc.edu/biomed/workshops/wk-97/NAPSA-97/napsa.html
or contact Nancy Blankenstein, biomed@psc.edu,  (412) 268-4960.

To register, please send the following registration form
to biomed@psc.edu

Registration deadline is July 20, 1997.

_____________________________________________________________________________

                        Pittsburgh Supercomputing Center
    
                      Biomedical Supercomputing Initiative



                                 APPLICATION FORM


Please complete the following form and return it with the corresponding
documentation. Direct inquiries to: Nancy Blankenstein
biomed@psc.edu or (412) 268-4960.

Application Deadline: July 20, 1997



                      PITTSBURGH SUPERCOMPUTING CENTER
                           BIOMEDICAL INITIATIVE


     NUCLEIC ACID AND PROTEIN SEQUENCE ANALYSIS WORKSHOP, July 20-25, 1997.
                                APPLICATION


Name:          ______________________________________________________________

Affiliation:   ______________________________________________________________

Address:       ______________________________________________________________
               (Business)
               ______________________________________________________________

               ______________________________________________________________
               (Home)
               ______________________________________________________________

Telephone:  ____________________________         ____________________________
                   (Business)                                (Home)

*Social Security Number:  _______-_____-_______ 

Citizenship:___________________

Electronic Mail Address:_____________________________________________________

Status: ___Graduate  ___Post-doctoral Fellow  ___Faculty  ___Other (specify)

Please indicate specifically any special housing, transportation or dietary
arrangements you will need: 

___________________________________________________

How did you learn about this workshop:_______________________________________


REQUIREMENTS:

Applicants must submit a completed application form and a cover letter. The
letter should describe, in one or two paragraphs, your current research,
and how participating in the workshop will enhance this research. Please
include a brief statement describing your level of experience with
computers. Faculty members, staff and post-docs should provide a
curriculum vitae. Graduate students must have a letter of recommendation
from a faculty member.

Please return all application materials six weeks before the workshop you are
applying for to

     Biomedical Workshop Applications Committee
     Pittsburgh Supercomputing Center
     4400 Fifth Avenue, Suite 230C
     Pittsburgh, PA 15213

Direct inquiries to: Nancy Blankenstein biomed@psc.edu, or (412)268-4960.

*Disclosure of Social Security Number is voluntary.

PSC does not discriminate on the basis of race, color, religion, sex, age,
creed, national or ethnic origin, or handicap.


From BIOSCI-REQUEST  Mon Jun 16 12:27:57 1997
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Message-ID: <UndNCFO00YUy0CDOE0@andrew.cmu.edu>
Date: Mon, 16 Jun 1997 15:27:13 -0400 (EDT)
From: Marcela Madrid <mm6n+@andrew.cmu.edu>
To: rna@net.bio.net
Subject: PSC Sequence Analysis Workshop - CORRECTED REGISTRATION DATE

The Pittsburgh Supercomputing Center is offering a
NUCLEIC ACID AND PROTEIN SEQUENCE ANALYSIS
workshop, July 20-25, 1997.

This intense workshop will teach the basics of sequence analysis, 
including remote supercomputing, database searching and pairwise 
sequence alignment, multiple sequence alignments, pattern 
identification, inverse structure prediction, and visualization of
macromolecular structures. Special emphasis will be placed on parameter
selection, and the mathematical and statistical properties of 
the algorithms and methods presented. Information will also be 
presented on the latest pattern identification techniques
including hidden markov models, advanced position-specific weight 
matrix techniques and bayesan estimation.

The workshop will consist of both lectures and extensive hands-on lab sessions.

In addition to the lab exercises, participants can work on their 
own research problems, with the help of the instructors.  
Participants are encouraged to bring their research data, but not 
required.

Instructors
Dr. Gary Churchill, Cornell University
Dr. David W. Deerfield II, Pittsburgh Supercomputing Center
Dr. Michael Gribskov, San Diego Supercomputer Center
Dr. Hugh B. Nicholas Jr., Pittsburgh Supercomputing Center
Alexander J. Ropelewski, Pittsburgh Supercomputing Center

For more information, please see
http://www.psc.edu/biomed/workshops/wk-97/NAPSA-97/napsa.html
or contact Nancy Blankenstein, biomed@psc.edu,  (412) 268-4960.

To register, please send the following registration form
to biomed@psc.edu

Registration deadline is June 20, 1997.

_____________________________________________________________________
 
                 Pittsburgh Supercomputing Center

               Biomedical Supercomputing Initiative



                         APPLICATION FORM


Please complete the following form and return it with the 
corresponding documentation. Direct inquiries to: 

Nancy Blankenstein
biomed@psc.edu or (412) 268-4960.

Application Deadline: June 20, 1997



                     PITTSBURGH SUPERCOMPUTING CENTER
                          BIOMEDICAL INITIATIVE


NUCLEIC ACID AND PROTEIN SEQUENCE ANALYSIS WORKSHOP,
July 20-25, 1997.

                              APPLICATION


Name:          _______________________________________________________

Affiliation:   _______________________________________________________

Address:       _______________________________________________________
               (Business)
               _______________________________________________________

               _______________________________________________________
               (Home)
               _______________________________________________________

Telephone:  _________________________         ________________________
                   (Business)                          (Home)

*Social Security Number:  _______-_____-_______ 

Citizenship:___________________

Electronic Mail Address:______________________________________________

Status: ___Graduate  ___Post-doctoral Fellow  ___Faculty  ___Other (specify)

Please indicate specifically any special housing, transportation or dietary
arrangements you will need: ___________________________________________________

How did you learn about this workshop:_______________________________


REQUIREMENTS:

Applicants must submit a completed application form and a cover 
letter. The letter should describe, in one or two paragraphs, 
your current research, and how participating in the workshop
will enhance this research. Please include a brief statement 
describing your level of experience with computers. Faculty 
members, staff and post-docs should provide a curriculum vitae.
Graduate students must have a letter of recommendation from 
a faculty member.

Please return all application materials by June 20, 1997 to

     Biomedical Workshop Applications Committee
     Pittsburgh Supercomputing Center
     4400 Fifth Avenue, Suite 230C
     Pittsburgh, PA 15213

Direct inquiries to: Nancy Blankenstein biomed@psc.edu, 
or (412)268-4960.

*Disclosure of Social Security Number is voluntary.

PSC does not discriminate on the basis of race, color, religion, 
sex, age, creed, national or ethnic origin, or handicap.


From BIOSCI-REQUEST  Thu Jun 26 03:32:35 1997
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          MSSERV.RZ-Berlin.MPG.DE (MX V4.1 VAX) with SMTP; Thu, 26 Jun 1997
          12:33:07 +0100
Message-ID: <33B24358.6D5A@mpimg-berlin-dahlem.mpg.de>
Date: Thu, 26 Jun 1997 14:24:25 +0400
From: "Pavel V. Baranov" <baranov@mpimg-berlin-dahlem.mpg.de>
Reply-To: baranov@mpimg-berlin-dahlem.mpg.de
Organization: Moscow State University
X-Mailer: Mozilla 3.01Gold (Win95; I)
MIME-Version: 1.0
To: rna@net.bio.net
Subject: Need your help
Content-Type: text/plain; charset=koi8-r
Content-Transfer-Encoding: 7bit

Dear collegues!
	Does anybody know enzyme that catalyzes hydrolysis of 3'-phosphate
group from  ribo- and deoxyribonucleotide?
	Thanks in advance
-- 
		Pavel Baranov
		Moscow State University

