Dear Arabidopsis Community,
We would like to draw your attention to a new database that we have =20
recently released at: http://signal.salk.edu/cgi-bin/exosome. This =20
database displays a genome-wide atlas of RNA targets of the exosome =20
complex, which plays a central and essential role in RNA metabolism. =20
These genome-wide high-resolution analyses have revealed novel aspects =20=
of stable structural RNA metabolism as well as uncovered numerous =20
novel exosome substrates including hundreds of noncoding RNAs, the =20
vast majority of which have not been previously described and belong =20
to a =93deeply hidden=94 layer of the transcriptome that can only be =20
visualized upon inhibition of exosome activity. We hope this database =20=
will provide another useful resource to the entire community of =20
Arabidopsis researchers.
Sincerely,
Brian D. Gregory
Postdoctoral Research Fellow
Ecker Lab
Salk Institute for Biological Studies=
