A POSTDOCTORAL POSITION is available at the Biotech Center, Rutgers Univers=
ity, in the laboratory of Prof. Eric Lam (http://aesop.rutgers.edu/~lamlab)=
for a highly motivated scientist interested in studying chromatin organiza=
tion and global regulation of genes via epigenetic control. Recently, we h=
ave established a set of about 300 mapped lines of novel transposants in Ar=
abidopsis with single Ds insertions that allows functional and structural c=
haracterization of global epigenetic control in living plants. This unique=
resource promises to reveal interesting new insights to the complex networ=
k of the epigenome using Arabidopsis as a paradigm. The successful applica=
nt will apply this collection of lines to examine global epigenetic control=
as a function of development and in response to stresses. In addition, th=
ese lines will also be used to screen for novel chemicals that can regulate=
epigenetic pathways using chemical biology approach. =20
The ideal applicant should have prior experience with molecular (ChIP a=
ssay, PCR, cloning, northern/Southern blotting, etc.) and biochemical (west=
ern blotting, enzyme assay, etc) techniques, advanced microscopy, and/or ch=
emical biology approaches. Knowledge of epigenetic mechanisms is desirable =
but not required. If you are interested in this position, please email a co=
ver-letter stating your research interests, a curriculum vitae, and contact=
information for three references to: Prof. Eric Lam, ericL89 from hotmail.com
The Biotech Center at Rutgers University is located in New Brunswick, N=
ew Jersey, and enjoys a convenient location close to the famous Jersey Shor=
e and Pocono Mountains while also easily accessible (within 1 hour by car o=
r train) to metropolitan areas such as New York City and Philadelphia. The=
Biotech Center at the School of Environmental and Biological Sciences in t=
he Cook Campus is well-equipped with advanced instrumentations for molecula=
r biology, biochemistry and microscopy. Rutgers University is an equal opp=
ortunity employer that strongly encourages underrepresented groups to apply=
for open positions.
=20
Related Publications:
"Genome-wide transposon tagging reveals location-dependent effects on trans=
cription and chromatin organization in Arabidopsis" Plant J. Published On=
line: Apr 12 2008; DOI: 10.1111/j.1365-313X.2008.03517.x
=93DNA hypomethylation reduces homologous pairing of inserted tandem repeat=
arrays in somatic nuclei of Arabidopsis thaliana=94 Plant J. 2005 Nov;44(=
4):531-40.
"Visualizing chromosome structure/organization" Annual Rev. of Plant Biolo=
gy, 2004; 55: 537-554.
"Chromatin of endoreduplicated pavement cells has greater range of movement=
than that of diploid guard cells in Arabidopsis thaliana" J. of Cell Scie=
nce, 2003; 116: 2195-2201.
"Detection of green fluorescence protein tagged chromosomes in live Arabido=
psis thaliana" Genome Biology, 2001; 2: 0045.1-0045.10.
Prof. Eric Lam=20
Biotechnology Center for Agriculture and the Environment
Professor of Plant Science,=20
Rutgers, The State University of New Jersey, U.S.A.
=
