From owner-7tms_r@net.bio.net Mon May 10 23:00:00 1999 Path: biosci!biosci!not-for-mail From: Dennis Fry Newsgroups: bionet.molbio.proteins.7tms_r Subject: GLP1 receptor Date: 11 May 1999 10:11:51 -0700 Organization: Abbott Laboratories Lines: 4 Sender: daemon@net.bio.net Approved: lfk@gcrdb.uthscsa.edu Distribution: world Message-ID: <7h9ocn$nb@net.bio.net> NNTP-Posting-Host: net.bio.net Greetings, Does anyone out there have or know of an antibody to the GLP-1 receptor? Any information would be appreciated. From owner-7tms_r@net.bio.net Mon May 10 23:00:00 1999 Path: biosci!biosci!not-for-mail From: Florence.Horn@EMBL-Heidelberg.de (Florence Horn) Newsgroups: bionet.molbio.proteins.7tms_r Subject: GPCRDB update Date: 11 May 1999 10:13:55 -0700 Organization: MRC Human Genome Mapping Project Resource Centre Lines: 63 Sender: daemon@net.bio.net Approved: lfk@gcrdb.uthscsa.edu Distribution: world Message-ID: <7h9ogj$or@net.bio.net> NNTP-Posting-Host: net.bio.net Heidelberg, 4-May-1999 Dear all, We are pleased to announce the May release of the GPCRDB (http://www.gpcr.org/7tm/). For the first time, we have made an attempt to import GPCR sequences from the TREMBL databank (Translation of EMBL entries). The software to sensitively search for GPCRs in TREMBL was written by Andreas Heger and Liisa Holm at the EBI. (GPCRDBsup: http://circinus.ebi.ac.uk:8901/html/index.html) The TREMBL entries contain less annotation than the Swiss-Prot ones but their integration allow for a sizeable increase of sequence data. 385 TREMBL entries describe GPCR proteins sharing significant sequence homology with known GPCRS. Since the 17th of March, we also provide cDNA sequences and the corresponding pairwise alignments (protein/cDNA). All the computationally derived data (alignments, CMA results, phylogenetic trees) have been recalculated, as well as the snake-like plots. Thanks to the recent release of the tinyGRAP database version 7.0, our snakes now provide access to data for 7600 mutations (http://www-grap.fagmed.uit.no/GRAP/homepage.html). For those who like numbers the server holds: 1513 GPCR sequences (incl.346 fragments) 209 classes, families, sub-families, etc. 199 Multiple sequence alignments 179 Phylogenetic trees 1293 3D models by 7 depositors. You can get this data via anonymous FTP (see http://www.gpcr.org/7tm/htmls/ftpinfo.html). Please feel free to report any errors or omissions in the GPCRDB. Greetings, Florence Horn & Gerrit Vriend PS:Industrial companies which want to get the complete GPCRDB data content in-house can contact us. - -- 777777777777777777777777777777777777777777777777777777 Florence HORN email:horn@embl-heidelberg.de BIOcomputing phone: (49) 6221-387456 EMBL fax: (49) 6221-387517 Meyerhofstr., 1 69117 Heidelberg http://www.gpcr.org/7tm TMTMTMTMTMTMTMTMTMTMTMTMTMTMTMTMTMTMTMTMTMTMTMTMTMTMTM - ---