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different genes or splice variants?

Tobias McNultey yando.geo at yahoo.com
Sun Jul 7 17:12:46 EST 2002


I  looked for  the ortholog of  a  gene in 
Drosophila,
(where  there is  only one member of this  gene 
family)
in  another genome, Anopheles gambiae.

I  found the ortholog  but also two other isoforms
of this  gene.
Three isoforms *adjacent* to each other  on the
chromosome.
What's  more, the   intron/exon  boundaries between 
the
two most  similar  are conserved! 
Can someone  tell me  if  this is novel? I   don't
know  where to look.
I  have heard of clustering but these  are right
next to each other.
It  is  not alternative splicing  right?
I  observe:
  
-------A------------B------------C------------------a----b------c---

 where A and  are  homologous exons. If you had 
 alternativeplicing  the 
 genomic orgization would be different, right?  I
 would expec this:
 
--------A--------a-------B--------b--------C--------c-----
>  Can someone  clue me in. I am  just  getting
started
>  Genomics.
>  

=====



Moderated
bionet.genome.gene-structure



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