bionet.software.acedb FAQ

Bradley K. Sherman bks at s27w007.pswfs.gov
Mon Sep 27 13:37:28 EST 1993


Archive-name: acedb-faq
Last-modifed: 9/27/93
Version: 1.1

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Common Questions and Answers about ACEDB.

    This is the zeroth posting of this document.  Errors of
    commission or omission are unintentional.

    Please send comments and corrections to acedbfaq at s27w007.pswfs.gov.
    Curators of ACEDB databases should take note of Question 4 and
    keep me apprised of changes.

    I will submit the next version of this FAQ for Usenet
    archival storage.
        --Bradley K. Sherman

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List of questions in the ACEDB FAQ:

Q0:  What is ACEDB?
Q1:  What is the current version of ACEDB?
Q2:  What {hardware | software} do I need to run ACEDB?
Q3:  Where can I get ACEDB?
Q4:  What ACEDB databases exist?
Q5:  What written documentation exists for ACEDB?
Q6:  Where can I find further information about ACEDB?
Q7:  How should ACEDB be cited?
Q8:  Is ACEDB object-oriented?
Q411:Who contributed to this document?

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Q0:  What is ACEDB?

A0:  ACEDB is an acronym for A Caenorhabditis elegans Database.  It can
     refer to a database and data concerning the nematode C.  elegans,
     or to the database software alone.  This document is concerned
     primarily with the latter meaning.  ACEDB is being adapted by many
     groups to organize data about diverse species [see Q4].

     ACEDB allows for automatic cross-referencing of items when loaded
     and allows for hypertextual navigation of the links using a mouse.
     Certain special purpose graphical displays have been integrated
     into the software.  These reflect the efforts of molecular
     biologists in constructing genetic and physical maps of genomes.

     ACEDB was written and developed by Richard Durbin (MRC LMB
     Cambridge, England) and Jean Thierry-Mieg (CNRS, Montpellier,
     France), beginning circa 1990.  It is written in the C programming
     language and uses the X11 windowing system to provide a platform
     independent graphical user interface.  The source code is publicly
     available [See Q3].  Durbin & Thierry-Mieg continue to develop
     the system, with contributions from other groups including
     Lawrence Berkeley Laboratory and the European integrated Genome
     Project.

     A description by Durbin & Thierry-Mieg:
         ACEDB does not use an underlying relational database
	 schema, but a system we wrote ourselves in which data
	 are stored in objects that belong in classes.  This is
	 nevertheless a general database management system using
	 caches, session control, and a powerful query language.
	 Typical objects are clones, genes, alleles, papers,
	 sequences, etc.  Each object is stored as a tree,
	 following a hierarchical structure for the class (called
	 the "model").  Maps are derived from data stored in tree
	 objects, but precomputed and stored as tables for
	 efficiency.  The system of models allows flexibility
	 and efficiency of storage -missing data are not stored.
	 A major advantage is that the models can be extended
	 and refined without invalidating an existing database.
         Comments can be added to any node of an object.

         Current display modes are:
             TREE   for text type objects: papers, authors, genes
	            etc.
             GMAP   genetic map
             PMAP   physical map (Sulston contig style)
             SEQ    DNA sequence - symbolic, features, sequence
	            and translation
             GRID   hybridisation patterns for a probe to a clone
	            grid
             BIBLIO bibliography attached to any object display
	            modules under development:
             CMAP   whole chromosome physical map plot
             GEL    agarose gel simulation derived from sequence

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Q1:  What is the current version of ACEDB?

A1:  1-10.  It was released Summer 1993.  The next release will be
     2.0.

----------------------------------------------------------------------
Q2:  What {hardware | software} do I need to run ACEDB?

A2:  ACEDB currently runs on the following Unix sytems, under X11:
         Sun SPARCstation 1, 1+, 2, IPC, IPX:
         SPARCstation 10 running Solaris:
         DEC  DECstation3100, 5100 etc.
         DEC  Alpha/OSF-1
         Silicon Graphics Iris series
         PC 386/486 with Linux (public domain Unix)
    Other Unix:
        There exist, or have existed, ports onto Alliant, Hewlett-
	Packard, IBM R6000, NeXT, Convex.   You may have to contact
	the developer responsible for the port to make these real.
    Macintosh:
        A port to the Macintosh may become available by the end of 1993.


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Q3:  Where can I get ACEDB?

A3:  All the files are available in the following public access
     accounts (anonymous ftp sites) accessible via Internet:
          lirmm.lirmm.fr         (193.49.104.10)  genome/acedb
          cele.mrc-lmb.cam.ac.uk (131.11.84.1)    pub/acedb
          ncbi.nlm.nih.gov       (130.14.20.1)    repository/acedb

----------------------------------------------------------------------
Q4:  What ACEDB databases exist?

A4:  Database : ACeDB
     Species : Caenorhabditis elegans
     Availability :
     Current version: 1-10
     Curator : Jean Thierry-Mieg
     Curator : Richard Durbin
     Contact : rd at cele.mrc-lmb.cam.ac.uk
     Contact : mieg at kaa.cnrs-mop.fr
     Last_update : Sept. 1993

     Database : AAtDB
     Species : Arabadopsis thaliana
     Availability : 
     Curator : John Morris
     Current version: 1-5
     Contact : curator at frodo.mgh.harvard.edu
     Last_update : Sept. 1993

     Database : GrainGenes
     Species : Wheat, barley, oats, relatives
     Availability : Gopher greengenes.cit.cornell.edu port 70
     Availability : ACEDB version by ftp, on request from the curators
     Curator : David E. Matthews
     PI : Olin D. Anderson
     Contact : matthews at greengenes.cit.cornell.edu
     Contact : oandersn at wheat.usda.gov
     Last_update : Sept. 1993

     Database : SolGenes
     Coverage: Solanaceae - tomato, potato, pepper (eventually)
     Availability : Beta ACEDB via login or tar file
     Curator : Edie Paul
     Contact : epaul at nightshade.cit.cornell.edu
     Last_update : Sept. 1993

     Database : RiceGenes
     Species : Rice (O. sative)
     Availability : under development, login at own risk
     Curator : Edie Paul
     Contact : epaul at nightshade.cit.cornell.edu
     Last_update : Sept. 1993

     Database : SoyBase
     Species : Soybeans
     Curator :  Lisa Lorenzen
     PI : Randy Shoemaker
     Contact : lorenzen at mendel.agron.iastate.edu
     Last_update : Sept. 1993

     Database : TreeGenes
     Species : Forest trees, Pinus taeda
     Availability : contact curator
     Curator : Bradley K. Sherman
     PI : David B. Neale
     Contact : Dendrome at s27w007.pswfs.gov
     Contact : bks at s27w007.pswfs.gov
     Contact : dbn at s27w007.pswfs.gov
     Last_update : Sept. 1993

     Database : 21Bdb
     Species : Homo sapiens
     Availability : by request, via ftp, gopher
     Curator : Donn F. Davy
     Contact : DFDavy at lbl.gov
     Contact : aggarwal at genome.lbl.gov
     Focus : STS content mapping & sequencing of Human Chromosome 21
     PI : Jasper Rine
     PI : Michael Palazzolo
     PI : Chris Martin
     PI : Jan-Fang Cheng
     Last_update : Sept. 1993

     Database : Flydb
     Species : Drosophila melanogaster
     Availability : by request only, via ftp
     Curator : Suzanna E. Lewis
     Contact : SELewis at lbl.gov
     Focus : STS content mapping project summary
     PI : Gerald Rubin
     PI : Mike Palazzolo
     PI : Dan Hartl
     PI : Alan Spradling
     Last_update : Sept. 1993

     Database : ChlamyDB
     Species : Chlamydomonas
     PI : Elizabeth Harris
     Last_update : Sept. 1993

     Database : AAnDB
     Species : Aspergillus nidulans
     PI : LeLand Ellis
     Last_update : Sept. 1993

     Species : Bovine
     PI : LeLand Ellis
     Last_update : Sept. 1993

     Species : Sorghum
     PI : LeLand Ellis
     Last_update : Sept. 1993

     Darabase : MycDB
     Species : Mycobacterium
     PI : Staffan Bergh
     PI : Thierry Garnier
     Last_update : Sept. 1993

     Database : EcoDB
     Species : E. coli
     PI : Staffan Bergh
     Last_update : Sept. 1993

     PI : Scott Chasalow
     Species : Potato
     Contact : Scottish Crop Institute, Dundee
     Last_update : Sept. 1993

     PI : George Murphy
     PI : David Flanders
     Species : Arabidopsis t.
     Contact : J. Innes Center, Norwich, England
     Last_update : Sept. 1993

     PI : David Bentley
     Species : Homo sap.
     Contact : Sanger Centre, Cambridge, England
     Last_update : Sept. 1993

     Database : MaizeDB
     Species : Maize
     Curator : Mary Polacco
     Contact : University of Missouri, Columbia, MO
     Last_update : Sept. 1993

     [Curators:  Please submit an entire paragraph in
      this format for inclusion or update. --bks]


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Q5:  What written documentation exists for ACEDB?

A5:  The primary documents are included in the Software
     distribution in the wdoc subdirectory:
         acedb -- A C. elegans Database: I. Users' Guide.
         acedb -- A C. elegans Database: II. Installation Guide.
         acedb -- A C. elegans Database: III. Configurat



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