Longevity in C. elegans

[Jim Cummins]

A recent paper in Nature (Kenyon C, Chang J, Gensch E, Rudner A,
Tabtiang, R: "A  C. elegans mutant that lives twice as long as wild
type". Nature 366: 461-646: 1993) demonstrated that a single mutation
in a gene involved in development (daf-2) results in a 2.3  fold
increase in healthy, fertile lifespan.    Anyone have any ideas on how
this might function?

Jim Cummins                   
School of Veterinary Studies
Murdoch University
Western Australia 6150  Tel +61-9-360 2668 Fax +61-9-310 4144
For every complex problem there's a simple solution.  And it's wrong!