Recent Reviews on Cell Ageing

Sydney Shall bafa1 at
Sun Feb 14 15:31:13 EST 1993

Recently, several people have enquired for reviews on ageing.

There has appeared in the January issue of Physiological Reviews

a review on;

Cellular and Molecular Mechanisms of Aging.

By J. Fred Rice,

of the Department of Physiology, Tufts University School of Medicine,

Boston, massachusetts, U.S.A.

In this review he covers the following arteas;

1. Evolution of Ageing,

2. Life-Prolonginh effects of caloric restriction.

3. long-lived mutants.

4. Cellular Senescence.

5. Cellular senescence and organismal ageing.

6. Senescent phenotype in cultured cells is dominant.

7. Causes of cellular ageing.

                   A. Error theories.

                   B. Program theories.

        I think some people might find this review a useful introduction

to the field; others might find it thought-provoking.

Sydney SHALL.


Sydney SHALL,
Laboratory of Cell and Molecular Biology,
Biology Building,
University of Sussex,
East Sussex BN1 9QG,

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