fas gene

[VERPHELD at VTVM1.CC.VT.EDU]

Autoimmune prone MRL/lpr mice have been reported to have deffective Fas genes
which would presumably alter the negative selection process in the thymus.  I
would like to know if anybody has any thoughtson why this deffective fas gene w
ould alter T cell development and yet have no effect on other developmental
processes mediatred through apoptosis.
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  Daniela I. Verthelyi
  Virgina Tech.
  USA
  VERPHERLD at VTVM1