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Autoimmune prone MRL/lpr mice have been reported to have deffective Fas genes
which would presumably alter the negative selection process in the thymus.  I
would like to know if anybody has any thoughtson why this deffective fas gene w
ould alter T cell development and yet have no effect on other developmental
processes mediatred through apoptosis.
  Daniela I. Verthelyi
  Virgina Tech.

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