Telomerase

Sydney Shall S.Shall at sussex.ac.uk
Thu Jan 13 15:12:09 EST 1994


In answer to recent query as to where the enzyme telomerase is found;
my understanding is that it is found in germ cells, but it is also
found in cancer cell lines that grow indefinitely.  This latter fact
is part of the evidence that this enzyme is required for immortal
growth, and that its absence is responsible for mortalization of a
culture, becuase without this enzyme the telomeres in the cells will
shorten till they finally reach a fatal threshold.

	I hope this helps.

	
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Sydney SHALL,
Laboratory of Cell and Molecular Biology,
Biology Building,
University of Sussex,
Brighton,
East Sussex BN1 9QG,
ENGLAND.

Telephone: +44.273.67.83.03

FAX: +44.273.67.84.33

E-Mail:

	Janet:		S.Shall at uk.ac.sussex

	Elsewhere:	S.Shall at sussex.ac.uk

	EARN/BITNET:	S.Shall%sussex at ukacrl


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