Necrosis versus Apoptosis

LOCKSHIN, RICHARD A YPRLBIO at sjumusic.stjohns.edu
Thu Jan 5 09:54:23 EST 1995


In article <9412291617.AA15897 at pclsp2> vinz at PCLSP2.KUICR.KYOTO-U.AC.JP (Vincenzo Nardi-Dei) writes:
>Gold wrote:
>
>>Hey, has anyone out there read "Ideas in Pathology, Programmed Cell Death:
>>Necrosis versus Apoptosis" in Modern Pathology, Volume 7, pages 605-609
>>(1994).
>>
>>The gist of the article is that the term "apoptosis" adds to the confusion
>>of the
>>study of cell death, rather than clarifying it.  And that the distinction
>>between necrosis and apoptosis lacks clarity and is "confusing and ...
>>unintelligible".
>>
>>Comments, netters...
>
>So how do they propose to define programmed cell death?
>
programmed cell death refers to the identification of a sequence
of events, now presumed to be gene activity, that leads a cell
to become irreversibly committed to death.  See articles on
original use of term (Lockshin and Williams, 1964-1965, J.
Insect Physiology) or review by Saunders, Science, 1966, or
any of several recent reviews (Lockshin, Zakeri & Lockshin,
etc) in Ann Rev NY Acad Sci, FASEB J, Cold Spring Harbor Symp,
elsewhere.
Richard A. Lockshin/Dept. Biol. Sci. St. John's U.8000 Utopia Pkwy
Jamaica NY 11439 USA/Phone 718: 990-1854/ Fax 718: 380-8543
>Vincenzo Nard-Dei
>
>Institute for Chemical Research
>Kyoto University
>
>
>.
>.





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