MFossel mfossel at aol.com
Sun Jul 28 11:42:54 EST 1996


The evidence is sketchy.  The serum level of DHEA falls progressively
after early maturity.  DHEA is the most common (by concentration) steroid
in human serum, its function is unclear, yet there are no known human live
births in which the infant does not have DHEA (suggesting its importance
either per se, as part of a metabolic chain, or as the product of an
enzyme which has other far more important functions than making DHEA). 
Twelve years ago I tried ten related steroids (sterically similar rather)
on Sprague Dawley rats.  All of them had exactly the same average lifespan
and tumor rates...   Oh Well.

Incidentally, if you DO take DHEA, you might try to obtain the sulfated
version (DHEA-S) as it has better first pass kinetics (it gets past the
liver better if you eat it) than does DHEA itself.

Best wishes,
Michael Fossel, MD, PhD
Author, Reversing Human Aging

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