HB-EGF as a protooncogene ?

Jana Briestanska briesta1 at JEFLIN.TJU.EDU
Thu Jul 17 12:51:36 EST 1997

What=92s your opinion?

Recently we have discussed in our lab if growth factors like HB-EGF =

can be considered a protooncogenes.

To my opinion:  =

when considering the definition of a protooncogene is a gene involved =

in proliferation and differentiation pathways, and when mutated it
causes in concert with other functionally related genes a cancer, then
HB-EGF could be also considered a protooncogene.

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