longevity in C. elegans 9

Vladimir V. Bakaev vlad at bakaev.nsk.ru
Sat Oct 18 08:10:14 EST 1997


>From The Worm Breeder's Gazette, 1996, v. 14, No. 5, p. 69.

    AN ATTEMPT TO SLOW AGING IN C. elegans. 6. NO EFFECT OF
      ROYAL JELLY EXTRACT WATER SOLUION IN CONCENTRATION
                         1:100 000 000

     Vladimir V. Bakaev, box 45, Novosibirsk, 630107, USSR

In this investigation nematodes C.  elegans lived in liquid me-
dium  with  E.  coli  and water solution of royal jelly extract
in concentration 1:100 000 000 in order to study its effect  on
longevity of these worms in comparison with control,  where ne-
matodes lived without this extract.  Three adult animals (3 - 5
days  old)  were kept in microtitre wells containing 0,75 ml of
liquid medium (with E.  coli and without royal  jelly  extract)
during 4 hours, then they were discarded and newborn larvae we-
re transferred in next wells (with royal jelly extract  in  any
concentration) every day (one worm in one well).  This investi-
gation was carried out in room temperature  and  in  the  dark-
ness.
The obtained results were as follows (mean and standard error):

               Control group        Experimental group
                      Longevity (in days)
Mean          17,19 +/- 1,03        16,31 +/- 1,08
Maximal       29                    30
Minimal        8                    7
                       Number of animals
              36                    35

Conclusion: The water solution of royal jelly  extract  has  no
effect on C. elegans longevity.
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