cause of aging

Tony B. Csoka csoka at ITSA.UCSF.EDU
Wed Aug 19 21:04:45 EST 1998


Very interesting discussion going on here. Particularly insightful
comments from Dr. Harris.
 Thought you might find this paper interesting:


> Mech Ageing Dev 1992 Aug;65(1):85-107
>
> The proliferation theory of rejuvenation.
>
> Danner DB
>
> Laboratory of Molecular Genetics, National Institute on Aging, Baltimore, MD 21224.
>
> A theory concerning the molecular basis of rejuvenation is presented that postulates a central role for cell proliferation. This theory assumes that
> aging is due to the accumulation of multiple forms of molecular damage and that rejuvenation is due to repair. The advantages of proliferation
> as a means of repair are described and it is proposed that cell proliferation is required for full rejuvenation. This proliferation theory offers
> several advantages: a different perspective on the question of which organisms age; an explanation of aging-related phenomena that are not well
> handled by traditional aging theories; a novel approach to altering the aging rate; and testable implications for the design of new experimental
> systems and therapeutic interventions.
>

I read it a few years ago, but your discussion has prompted me to read
it again.
How do I sign on to this newsgroup, I've been following from the
archives?

T. Benjamin Csoka






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