Telomeric Theory of Aging

Beverly Erlebacher bae at cs.toronto.edu
Thu Aug 20 11:34:28 EST 1998


In article <6rh6dv$qug$1 at ostrich.cybercomm.net>,
Jennifer Ann Petersen <jennifer at jenniferpetersen.com> wrote:
>Beverly Erlebacher wrote in message
><1998Aug19.135543.14736 at jarvis.cs.toronto.edu>...
>>Note that the telomerase knock-out mice had normal life spans for *six*
>>*generations* of steadily decreasing telomere length.  THe only apparent
>>effect was that the sixth generation was sterile.
>
>What did the mice die from?

I don't remember if the paper said, but the important point is that the
life span was no different from that of the mouse strain that the knock-out
line originated from.  I don't know what lab mice normally die of.  Boredom?





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