Telomerase Expression in Human Cells!

Deacon Sweeney sweeney.2 at
Tue Dec 29 16:49:29 EST 1998

OK, so the telomerase gene being expressed in cells does not cause
cancer... but, as I understand it, telomerase has never been posited to
cause cancer.  Telomerase resupplies telomeres, but does not interfere
with cell-cycle controls, eg, does not cause cancer.  The limited number
of telomeric repeats keep cell populations from making too many babies,
something which keeps benign tumors benign.  Why would anyone want to
allow their constanly forming benign tumors to reproduce indefinitely? 
Wouldn't malignancy skyrocket?

Deacon Sweeney
Wright State University

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