Telomerase Expression in Human Cells!

Jennifer Ann Petersen jennifer at jenniferpetersen.com
Thu Dec 31 09:33:54 EST 1998


Doug Hosack wrote in message <76g0kt$jhc1 at icet.net.nih.gov>...
><snip>
>telomerase into some strain of immunocompromised mice, such as SCID mice or
>nude mice.  Technically, this would be *in vivo* expression of telomerase.
>Since the immune systems of these mice could not reject the human cells,
the
>researchers could gather data about "cancer-associated physical and
>biochemical characteristics."


Wouldn't the reduced functionality of the immune system skew the results? It
seems to me the mice would be more susceptible to cancer.






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