Telomerase Expression in Human Cells!

M. Prakash Hande phande at bccancer.bc.ca
Thu Dec 31 15:06:28 EST 1998


Very interesting and unbelievable. The same cell lines were used by these
two groups funded by the same company. Is presence of 6 to 7 % cytogenetic
abnormalities (among them translocation, tetraploid cells and telomere
associations) considered as normal karyotype? If so, why billions of dollars
are spent to understand one translocation or one mutation or one abnormality
which has minimal impact on human health according to these papers.

>Geron Announces First In Vivo Data Indicating Telomerase Expression in
>Normal Human Cells Extends Their Replicative Lifespan Without Oncogenic
>Transformation
>
I am lost here, what is the definition of IN VIVO in those two papers?

Prakash







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