Very odd abstract found. Any comments?

James james at nospam.com
Wed Sep 9 22:59:42 EST 1998


Excelife wrote:

> In article <35f71d5b.28673484 at nntp.ix.netcom.com>, ufotruth at ix.netcom.com
> says...
> >
> >Everyone,
> >
> >I found the following abstract on the web. I was wondering if anyone
> >had any comments about it. From everything I have read before it
> >seemed like it had been proven that cells taken from younger
> >individuals did indeed divide more times than cells from older
> >individuals.
> >
> >Could the experiment mentioned in the following abstract be flawed or
> >in error? Hey, it might be for real but it seems to me that it has
> >already been tested many times that cells from younger people divide
> >more times than from older people....
> >
> >Anyway.. Here is the abstract.
> >
> >Best Regards,
> >William
> >
> >----
> >
> >Vol. 95, Issue 18, 10614-10619, September 1, 1998
> >
> >
> >Cell Biology
> >Relationship between donor age and the replicative lifespan of human
> >cells in culture: A reevaluation
> >
>
>
> One particular study comes to mind that doesn't contradict these findings but
> does provide an explanation for them.
>
> In this study it shows that telomeric loss is not consistent over the course
> of aging.  Telomeric loss is related to cellular growth rates that vary in
> the course of development and it would not be unexpected that replicative
> life span of cells from persons of diverse ages might be similar.

[snip]

I don't think that explanation works because statistically it should average
out.  If there is a relationship between replicative potential and age, whether
or not there is a lot of varuance, and whether or not it is linear, you should be
able to see it with a large sample size.





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