Antiaging Research Priorities [was Re: Major Criticisms of
browley at GALAXY.UCR.EDU
Thu Sep 17 15:28:48 EST 1998
Thomas Mahoney/ Excelife wrote:
>> While CR mice do live longer than mice whose diet is not restricted they
>> no longer than than other mice on CR. Their life span has not been
>> by CR only their life expectancy has been increased.
>I really have no idea what this is supposed to
>mean. I assume that it has something to do with an average versus maximum
>argument that you are trying to make.
>Regardless, I do not believe that you are correct. Caloric restriction
>shown to increase both average and maximal lifespan (see Yu et al. 1990,
>al. 1982, Sohal R et al. 1996, Weindruch R, 1996, etc.)
I think Tom Mahoney was making the point that CR is an environmental, not
genetic treatment for aging.
I agree that CR extends both average and maximal life span/expectation.
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