>Just some wild speculation here -
>>An opinion I have read is that increased lifespan under CR may be a way of an
>organism making the "best of a bad lot" when conditions are so bad that it
>would be unlikely that offspring would survive. Extending life until
>conditions improved may be a strategy that has evolved that optimises
>reproductive fitness under difficult conditions.
This would jibe with the observation, that CR started in older mice
(in post-reproductive age) does not have a life-prolonging effect.
Tolerance is wisdom's finest fruit