free radical production and aging
tmatth at netcom.ca
Mon Feb 15 22:25:41 EST 1999
hazel at springnet1.com wrote:
> > A comprehensive study was performed on the brains of various vertebrate
> > species showing different life energy potentials in order to find out if
> > free radicals are important determinants of
> > species-specific maximum life span.
> What is life energy potential?
I, too, was surprised to see such an 'non-scientific' phrase in the
abstract, but I assume they were using it as a euphemism for maximum
life span which is actually what they related things to.
I put it down to the fact that the authors were non-english speaking
> > Brain superoxide dismutase, catalase,
> > Se-dependent and independent GSH-peroxidases, GSH-reductase, and ascorbic
> > acid showed significant inverse correlations with maximum longevity, whereas
> > GSH, uric acid, GSSG/GSH, in vitro peroxidation (thiobarbituric acid test),
> > and malondialdehyde (measured by HPLC), did not correlate with maximum life
> > span.
> What is GSH and GSSG?
This is simpler.
GSH is reduced glutathione and GSSG is oxidized glutathione.
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