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Telomerase Expression in Human Cells!

Excelife excelife at earthlink.net
Fri Jan 1 05:53:49 EST 1999

I lost a few brain cells last night due to the effects of a few bubbles in a 
glass but let me see if I can straighten out some of the confusion in regards 
to Gerons recent announcement, which Tom was so thoughtful in providing.

Although the complete paper is not yet available, (and I was hoping to wait 
for its publication before responding), it seems that they are merely saying 
that the cells transfected with telomerase in their Science 1998 Jan 
16;279(5349):349-352  article are still reproducing in a phenotypically 
normal state.

They do, however, seem to be foreshadowing a future announcement with their 
references to "in vivo" determinations.

These pronouncements seem to confirm some of my own conjectures as to the 
potential of telomeric therapy on the effects of aging in reproducing 
cellular systems.

Those interested in the potential of the telomeric theory of aging can see my 
article with complete references at; 

Geron Corp. has patented some of the basic processes involved in this 
potential therapy but numerous other patents are necessary to achieve a 
viable therapeutic application of these procedures.  Lifeline Laboratories is 
funding some other basic research into this research so that no one company, 
country nor organization can obtain a monopoly on its application.

In conjunction with the insulin like growth factor (IGF-1), which can restore 
some functioning of muscle cells, and recent advances in the restoration of 
nerve cells, the basic outlines of procedures to extend the human life span 
are beginning to take shape.

Thomas Mahoney, Pres.
Lifeline Laboratories, Inc.

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