MiFR: Might CLA accelerate aging?

RSAMSON18 at cs.com RSAMSON18 at cs.com
Fri Mar 31 21:11:02 EST 2000


The process of utilizing stored fat for energy is nicely described in the 
book "Role of
Nutrition in Health and Disease" by William Cornatzer, MD, PhD.  First, the 
stored
triglycerides must be hydrolyzed by a hormone-sensitive lipase to release the 
fatty
acid and glycerol.  The fatty acids pass out of the adiocyte, combine with 
serum
albumin and are transported to tissues like heart and muscle to be 
metabolized for
energy.  This hormone-sensitive lipase in the adiocyte is the rate-limiting 
factor in
adipose tissue metabolism.  A number of hormones stimulate this enzyme;
epinephrine, norepinephrine, glucagon, thyroid stimulating hormone and adreno-
corticotropic hormone.
Fatty acids from adipose tissue enter the mitochondria of muscle, heart and 
liver with
the help of carnitine, which is synthesized from lysine and methionine.  The 
beta-oxidation of the fatty acid occurs in the mitochondria of muscle, heart 
and liver with
the help of enzymes including FAD (from Vitamin B-2) and NAD (from Vitamin 
B-3).
CLA may stimulate the pancreas to release glucagon to start this process.
I have been using a gelcap containing 500 mg of LCFFA (Long Chain FREE Fatty
Acid) to directly stimulate the pancreas to release glucagon and get rid of 
body fat.
It is much cheaper than CLA and is probably safer and more effective.  Over 
four years, the only observed side effect is some depletion of fatty 
nutrients such as
Vitamin D, which can be remedied with supplements if needed.
Ralph L. Samson
---





More information about the Ageing mailing list