Longevity Senescence and the Genome: looking for similar,but up to date review of literature

Mike Reilly mike_reilly_no_spam at bc.sympatico.ca
Sat May 13 12:41:33 EST 2000


That sounds like a decent place to start in terms of the free radical
theory.  I'm also looking for views on hormonal effects, a sound discussion
on the telomere theories (as opposed to the snake oil available on the net),
and other genetic components.  I liked Finches book for it's breadth of
coverage and grand overview.

My friend Stuart Carmichael did some work on Drosophila SOD a while back for
his Masters thesis, but has since gone to the private sector and no longer
works on it. Too bad, he kept me up to date (at least on the oxidative
theory) for quite a while.


>Finch's book is encyclopedic in its descriptions of aging or the
>lack thereof in many diverse species, but really sheds little light on the
>causes of aging.  I would strong recommend Aubrey de Grey's 1999 book
>"The Mitochondrial Free Radical Theory of Aging" for an admirable, though
>controversial, full frontal attack on the cause and possible prevention
>of mammalian aging.

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