extension of life-span with superoxide/catalase mimetics
Paul S. Brookes.
brookes at uab.edu
Tue Sep 5 08:46:09 EST 2000
If they're talking about MnTBAP and the other related porphyrins, it should
be remembered that they don't only scavenge superoxide, but also
peroxynitrite and to some extent nitric oxide and a whole host of other
reactive species. Whilst these compounds might work in worms, mammalian
studies haven't been so successful - they are quite toxic in rats.
Dr. Paul S. Brookes. (brookes at uab.edu)
UAB Department of Pathology, G004 Volker Hall
1670 University Blvd., Birmingham AL 35294 USA
Tel (001) 205 934 1915 Fax (001) 205 934 1775
The quality of e-mails can go down as well as up
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