Mutant Gene Symols of Arabidopsis thaliana

Mike Cherry 726-5955 CHERRY at FRODO.MGH.HARVARD.EDU
Wed Dec 30 10:54:43 EST 1992

Note: A printed copy of the following table, created by David Meinke,
was included in the recent postal mailing from the ABRC at Ohio State.
This table is now electronically available from the Arabidposis
Research Companion Gopher in the "Arabidopsis Genetic Maps and Tables"
folder. The information contained within this table has been
incorporated into the AAtDB database available via gopher and wais.
The next version of the Unix AAtDB database, release 1-4, will also
contain this information.

Special thanks go to David Meinke for volunteering to be the Genetics
Curator for Arabidopsis.

Mike Cherry
AAtDB Project

       Overview of Mutant Gene Symbols of Arabidopsis thaliana
		       David W. Meinke, Curator
		Phone: 405-744-6549; FAX: 405-744-7673
		     email: btnydwm at osucc.bitnet

The attached list presents a comprehensive summary of mutant gene
symbols currently being used in research with Arabidopsis thaliana.

This list is (hopefully) limited to mutants with viable seeds and
established phenotypes that have been examined in some detail.

Additional information on certain mutant phenotypes is given in

Reference laboratory refers to the individual(s) involved in the
initial identification or subsequent characterization of each class of
mutants.  This reference is included to help locate individuals who
could provide further information on specific symbols.

This list does not include information on the total number of loci
given the same mutant gene symbol.  For example, there are 250
distinct emb loci (emb1 to emb250) and one bio locus (bio1), but each
symbol is given a single line.

A separate list summarizing all well-characterized mutant loci by
symbol and number will need to be prepared in the future.

Note that in some cases on the attached list (*) the same gene symbol
has already been assigned to unrelated mutants.  These conflicts will
need to be resolved to avoid further confusion in the literature.

Suggested Protocol for the Future:  

Mutants should be characterized in some detail before a formal gene
symbol is chosen and published.  This analysis should include
(whenever possible) mapping the chromosomal location of the mutant

Complementation tests should be performed with mutants that map to
similar regions and/or exhibit similar phenotypes to ensure that the
"new" mutant has not already been identified and assigned a different

The standard system of nomenclature for Arabidopsis should be

A.  Mutant gene symbols should have 3 letters (underlined or italics)
in lower case.

B.  The wild-type allele should have these letters (underlined or
italics) in CAPS.

C.  Different genes with the same symbol are
distinguished by different numbers (for example: emb25 and emb26).

D.  Different alleles of the same gene are distinguished with a number
following a hyphen (for example: emb20-1 and emb20-2).

E.  When only a single allele is known, the hyphen (-1) is not needed
(thus: emb33 equals emb33-1 if only a single allele is known).

F.  When only a single gene is given a particular symbol, the number
is not needed (thus: lec equals lec1)

G.  The same nomenclature applies to both dominant and recessive

H.  Cloned wild-type genes should be in CAPS (underlined or italics)
and the protein products of these genes should be in CAPS only.

I.  When picking a mutant gene symbol, avoid the use of symbols that
might have another meaning (for example, CHS currently refers to both
the wild-type allele of a chilling sensitive mutant (chs), and the
cloned chalcone synthase gene).
A large number of form and color mutants obtained from the Kranz
collection are currently available through the Nottingham stock
center.  These mutants have names that do not correspond to the
nomenclature described above.  The best approach with this collection
may be to select new symbols for mutants that have been further
characterized in preparation for publication.

In Order to Minimize Duplication of Gene Symbols:  

The attached list of mutant gene symbols will be added immediately to
AIMS, AAtDB, and stock center catalogs, and will be periodically
updated.  Check this list before you choose a new gene symbol.

Then contact the current curator of gene symbols (David Meinke: phone
405-744-6549; FAX 405-744-7673; email btnydwm at osucc.bitnet) to reserve
your new symbol prior to publication and ensure that someone else was
not also planning to use the same symbol.

This protocol must be followed in order to minimize problems in the

Symbols can be reserved without details on mutant phenotype if there
is concern about providing too much information prior to publication.

Editors of journals will be informed of this policy to minimize the
chances of publishing a paper with a duplicate symbol.

Please report any mistakes or changes to the attached list to the curator as
soon as possible.  

Comments regarding this new system are also welcome.  Contact David
Meinke, Department of Botany, Oklahoma State University, Stillwater,
OK 74078, USA.

       Overview of Mutant Gene Symbols for Arabidopsis thaliana
	 This List Excludes Gene Symbols for Cloned Sequences
	    (*) = Change Suggested;  (**) = No Longer Used
	      Updated December 15, 1992; David W. Meinke

Symbol     Full Descriptive Name for Gene Symbol     Reference Laboratory
aba        ABA deficient                             Koornneef
abi        ABA insensitive                           Koornneef
aca        azetidine-2-carboxylic acid resistant     Lehle and Khan
acd        accelerated cell death                    Ausubel; Dangl
acf        suppressor of fca                         Dean
act        chloroplast glycerol-3-phosphate          Kunst and Somerville
           acyltransferase deficient                                   
adg        ADP glucose pyrophosphorylase deficient   Caspar
adh        Alcohol dehydrogenase deficient           Jacobs
ag         agamous (floral defective)                Koornneef
agr        agravitropic                              Maher 
ain        ethylene insensitive                      Van der Straeten 
alb        albina (white embryo and seedling)        Van der Veen; Relichova
ali        alien (abnormal trichomes)                Jurgens
amt        a-methyl tryptophan resistant (see mtr)   Town
an         angustifolia (narrow leaf)                Redei
ap         apetala (floral defective)                Koornneef
apt        adenine phosphoribosyl transferase        Moffatt and Somerville
ara        arabinose sensitive                       Cobbett
arc        accumulation and replication of           Pyke and Leech
as         asymmetric leaves                         Redei
aux        auxin-resistant                           Maher 
axr        auxin-resistant                           Estelle
bel        bell-shaped ovules, female sterile        Pruitt and Gasser
bic        bacterial induced chlorosis               Dangl
bio        biotin auxotroph                          Meinke
blu        blue light response defective             Hangarter
bp         brevipedicellus (downward siliques)       Koornneef
ca         caespitosa (short stems; bushy plants)    McKelvie; Redei
cad        cadmium sensitive                         Cobbett
cal        cauliflower (defective inflorescence)     Bowman and Meyerowitz
cdo        chardonnay (abnormal trichomes)           Jurgens
cer        eceriferum (shiny stems; reduced wax)     Dellaert; Koornneef
ch         chlorina (yellow green)                   Redei; Relichova
cha        chablis (abnormal trichomes)              Jurgens
chl        chlorate-resistant                        Feenstra; Crawford
chm        chloroplast mutator                       Redei
chm*       chlorominuta (light green)                Relichova
chp        chlorophyll mutant                        Koornneef 
chs        chilling sensititve                       Hugly and Somerville
ckr        cytokinin resistant                       Howell
clv        clavata (extra carpels)                   McKelvie; Koornneef
cn         convoluta (leaf shape; twisted stem)      Relichova
cnx        chlorate resistant (NR cofactor)          Braaksma and Feenstra
co         late flowering (replaces fg)              Redei
cob        cobra (root)                              Benfey
cop        constitutive photomorphogenic             Deng
           (light response in dark)
cp         compacta (semi dwarf)                     Koornneef
cp*        cupuliformis (leaf shape)                 Relichova
crc        crabs claw (floral defective)             Smyth
crk        crooked (abnormal trichomes)              Jurgens
crl        curly (defective cotyledons and leaves)   Medford
csi        cesium resistant                          Sussman
csr        acetolactate synthetase;                  Haughn and Somerville
           imidazolinone resistant
ctr        constitutive triple response              Ecker
dct        dicarboxylate transport defective         Somerville and Ogren
det        de-etiolated (light response in dark)     Chory
dip        disrupted (defective leaves, meristem)    Medford
dis        distorted trichomes                       Feenstra
dn         dentata (broad leaves, late flowering)    Relichova
doc        dark over-expression of cab               Chory
dwf        dwarf                                     Koornneef; Feldmann
dwf        auxin-resistant dwarf                     Mizra; Olsen
ein        ethylene insensitive                      Ecker
eir        ethylene insensitive root                 Ecker
ela        enhanced linolenate accumulation          Browse and Somerville
elf        early flowering                           Meeks-Wagner
emb        embryo-defective; includes lethals,       Meinke
           defectives, and pigment mutants
emf        embryonic flower                          Sung
er         erecta (short, upright stems)             Redei
esd        early flowering in short days             Coupland
eto        ethylene overproducer                     Ecker
etr        ethylene-insensitive                      Bleeker
ett        ettin (floral defective)                  Roe and Zambryski
fab        fatty acid biosynthesis defective         James and Dooner
fad        fatty acid desaturase deficient           Somerville
fae        fatty acid elongation defective           Kunst; Browse/Somerville
fas        fasciated (like clavata)                  Furner
fb**       (now gi)                                  Koornneef
fca        late flowering                            Koornneef
fd         late flowering                            Koornneef
fdh        fiddlehead (organ fusion)                 Lolle and Sussex
fdi        factor differentiation instability        Vizir
fe         late flowering                            Koornneef
fey        forever young (altered shoot apex)        Medford
fg**       (now co)                                  Koornneef
fha        late flowering                            Koornneef
fk         fackel (embryo defective)                 Jurgens
fl         folliculiformis (like clavata)       

More information about the Arab-gen mailing list