genomic sequencing

Dr S T May lsrei at csv.warwick.ac.uk
Wed Aug 10 17:33:32 EST 1994


Hi,

You might like to take a look at the GCG utility
'testcode'.

This predicts the coding/non-coding region of
a stretch of DNA without any knowledge of codon-usage 
for the given species.

As I understand it, it effectively makes its own
codon frequency table in all three frames and analyses
non-random usage of codons vs. random usage.
It then plots out the probability of coding (non-random)
and non-coding (random) against position such that you
get a graphical prediction of intron/exon regions.

If you have a codon-table file .. you can use 'frames'
with GCG.

Hope this helps,
Sean



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