reply to NAASC letter

Joe Ecker jecker at ATGENOME.BIO.UPENN.EDU
Mon Jun 6 18:25:34 EST 1994


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RESPONSE # 18

I propose that any funded Arabidopsis genomic sequencing center, being 
so efficient as they will claim to be in their application, include as part 
(at least 1/7) of its mission the directed sequencing of virtually any 
cosmid, plasmid, or even multi-kb PCR band that any Arabidopsis worker 
sends it.  This would add efficiency to many projects, and it would cause 
immediate payoff of the government resources committed to the center.  The 
center need not allow itself to be taken advantage of (for instance 
resequence plasmids looking for mutations) and 
it would spread this effort around as much as possible.  

    The resulting sequences would be deposited onto the databases without a 
delay of more than 6 months, or with no delay at all.  

    This would circumvent the inefficient DNA sequencing operations that 
now consume more research resources than they should.  It might help 
to get everyone behind the project, since many would stand to benefit from 
it early.
Barnes at biodec.wustl.edu    -------------------------
Wayne M. Barnes, Ph.D.             fax: 314/362-7183
Dept. Biochemistry 8231, Washington Univ. Med.School
St. Louis, Missouri 63110 USA       ph: 314/362-3351

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