A/T profiles of genomic seq
dan_szymanski at QMS1.LIFE.UIUC.EDU
Wed Feb 8 01:02:29 EST 1995
Subject: Time:11:49 PM
OFFICE MEMO A/T profiles of genomic sequences Date:2/7/95
I am analyzing the distribution of A/T sequence motifs in Arabidopsis
genomic sequences; specifically the distribution of 6 contiguous A/T base pair
motifs. This is a functional binding site for HMGa (high mobility group)
chromosomal proteins. Preliminary analyses have shown that the "A/T profile"
of HMGa sites for Arabidopsis genes depends on the expression profile of the
gene. Constitutively expressed genes differ substantially from inducible or
genes with a specific tissue specificity.
I would like to extend this work to as many genomic sequences as possible to
see if this pattern holds true for all genes.
I would greatly appreciate it if anyone who is working with a well
characgterized promoter to send me some further information. The best case is
that of a gene family where members have unique expression patterns. In terms
of describing the expression of the gene, three parameters are important:
level of expression,
The more responses I get the better. If you have a gene that fits the bill, I
would greatly appreciate it if you would provide the following information.
Genebank Accession number:
Thanks a lot,
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