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postdoc position available

Cardy Raper craper at MOOSE.UVM.EDU
Thu Nov 30 13:49:10 EST 1995

self/nonself recognition in a filamentous fungus with multiple mating
types.  Funding available for at least three years.   Start date  could be
as early as January '96.   Qualified candidates must have experience in
genetics and molecular biology.

We have isolated and sequenced several pheromone and pheromone receptor
genes that reside in the two multispecific B mating-type loci of the
Basidiomycete Schizophyllum commune.  These genes encode molecules for
recognition of self versus many nonselves resulting in the initiation of a
defined pathway of sexual development leading to dikaryosis and mushroom
production.  Many mutants are available to study this process at the
molecular level.  This research involves DNA sequencing and sequence
analyses, PCR amplification and cloning, nucleic acid hybridizations, in
vitro mutagenesis, DNA mediated transformation, and identification of genes
thought to be part of a signal transduction pathway, downstream of the
pheromone/receptor interactions.  Experiments designed to identify and
locate gene products in the cell are also planned.  

Our lab is located in a new building, fully supplied with the necessary and
latest  equipment to carry out this research.  The Department, which has
tripled in size over the past several years, includes 24 faculty members
representing a wide variety of interests in molecular genetics including
signal transduction, morphogenesis and cell-cycle control in yeast, 
mechanisms of DNA damage and repair, transcription complexes, and ribozyme
function.  It provides a cooperative learning environment for students and
postdocs at all levels. 

If interested, please send letter of application, curriculum vitae,  names
and addresses -- including e-mail address and/or phone numbers -- of three
persons who can evaluate you as a candidate. If preferred, reply using
e-mail address. 
                Dr. Carlene A. Raper (craper at moose.uvm.edu)
                Dept. Microbiology and Molecular Genetics
                The L. P. Markey Center for Molecular Genetics
                Stafford Hall, Tel. (802) 656-1115; Fax. (802) 656-8749; 
                University of Vermont, Burlington VT 05405

For published information, look for Wendland et al, 1995, EMBO Journal, vol
14, no. 21, pp. 5271-5278

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