clustering of mutations within an EMS mutated population?
gfv94001 at uconnvm.uconn.edu
Sun Nov 17 22:30:12 EST 1996
Has anyone experienced a clustering of mutations within an EMS mutated
population? The seven alleles I'm sequencing have shown unique
mutations, all within 400 bases of each other (in a 1.2Kbp gene). My
only idea is that the gene may be highly expressed during the time in
which the EMS is doing it's job, leaving the gene easily mutated within
a certain region. Any Ideas?
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