clustering of mutations within an EMS mutated population?

Gary Vanzin gfv94001 at uconnvm.uconn.edu
Sun Nov 17 22:30:12 EST 1996


Has anyone experienced a clustering of mutations within an EMS mutated 
population?  The seven alleles I'm sequencing have shown unique 
mutations, all within 400 bases of each other (in a 1.2Kbp gene).  My 
only idea is that the gene may be highly expressed during the time in 
which the EMS is doing it's job, leaving the gene easily mutated within 
a certain region.  Any Ideas?  




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