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homologue vs ortholog

Lee Meisel meisel at AESOP.RUTGERS.EDU
Mon Sep 2 16:38:30 EST 1996


Recently when reading a variety of papers I have seen ortholog and
homologue used in similar context.  I'm pretty sure there is a
difference between ortholog and homologue but am unsure of what that
difference is.  Unfortunately, ortholog is not in the Webster's
dictionary or in a genetic dictionary we have available.  Could someone
please explain the difference between ortholog and homologue, as well as
the criteria necessary to define a sequence as an ortholog or a

I will post the responses if anyone else expresses an interest.

Thank you in advance.

Lee Meisel (meisel at aesop.rutgers.edu)
Eric Lam's Lab
Rutgers University

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