post doc ads

Catherine Ronning cronning at tigr.org
Tue Aug 17 19:56:58 EST 1999




The Institute for Genomic Research has an opening for a
Postdoctoral Research Associate to work
on the NSF-funded project, "Generation of a Tomato EST Database."  In
collaboration with Cornell University, we are sequencing a total of
90,000 - 150,000 ESTs from a variety of tomato tissues, including
shoot, carpel, seed, disease challenged, developing fruit, etc.  The
sequence data are being used to construct the TIGR Tomato Gene Index
(http://www.tigr.org/tdb/lgi/index.html).  Representative clones from
the index will be used to construct a non-redundant tomato clone set
representing the distinct core tissues from which the ESTs were
derived. Microarrays for global gene expression studies will be built
from these clones.  We anticipate that this research will lead to
significant increases in the understanding of growth and development,
metabolic processes, mechanisms determining yield, and other plant
processes.


Requirements include a Ph.D. in plant genetics, physiology, or
pathology, and working knowledge of molecular biology techniques.
Experience with microarray production is highly desirable.  Knowledge
of relational database systems, SQL, and PERL is not necessary but
helpful; however, an aptitude for computer-based analysis, familiarity
with using public databases (eg, GenBank) and willingness to learn such
programs are essential.  The successful candidate will be responsible
for tracking clones and data throughout the pipeline to ensure quality,
and for development and analysis of tomato microarrays.  The candidate
will work with the Gene Index team, and will interface with our
collaborators at Cornell University.  He/she will be expected to use
state- of -the-art bioinformatics tools for data analysis and will have
the opportunity to pursue research interests in functional genomics as
it relates to this project.


TIGR has an active plant genomics research program that includes
structural and functional genomics.  The potato project will complement
existing plant genome projects at TIGR that include: Arabidopsis genome
sequencing and annotation, microarray analysis, disease resistance;
rice genome sequencing and annotation; tomato EST sequencing;
development of computational methods for plant genomics.  Please
contact Dr. C.M. Ronning, Collaborative Investigator, at
cronning at tigr.org.


--------------------------------------------------------------------------------


The Institute for Genomic Research has an opening for a Postdoctoral
Research Associate to work on the NSF-funded project, "Tools for Potato
Structural and Functional Genomics for Application to Analysis of
Responses to Pathogens" in collaboration with  U. of California
Berkeley, Cornell U., U. of Minnesota, and U. of Wisconsin (pending
final notification of award).  At TIGR, we will be sequencing and
annotating BACs  from wild potato genomes identified as containing
genes for Phytophthera  infestans (Late Blight) resistance, and
generating  55,000  ESTs from a variety of potato tissues.  These ESTs
will be annotated and used to construct the TIGR Potato Gene Index
(http://www.tigr.org/tdb). Finally, specific ESTs will be selected and
arrayed to fabricate potato cDNA microarrays, which will be used to
survey gene expression in response to P. infestans infection and during
disease development.  The tools developed from this research will lead
to significant increases in the understanding of molecular genetic and
biochemical events underpinning the response of potato to P.
infestans.


Requirements include a Ph.D. in plant science (genetics, physiology,
pathology), and extensive knowledge of molecular biology techniques.
Experience with microarray production is highly desirable.  Knowledge
of relational database systems, SQL, and PERL is not necessary but
helpful; however, an aptitude for computer-based analysis, familiarity
with using public databases (eg, GenBank) and willingness to learn such
programs are essential.  The successful candidate will be involved in
all aspects of the EST/BAC portions of this project , and will be
responsible for utilizing EST sequence data to develop potato
microarrays.  The candidate will work with the Gene Index team and will
interface with our collaborators .  He/she will be expected to use
state-of-the-art bioinformatics tools for data analysis and will have
the opportunity to pursue research interests in functional genomics as
it relates to this project.


TIGR has an active plant genomics research program that includes
structural and functional genomics.  The potato project will complement
existing plant genome projects at TIGR that include: Arabidopsis genome
sequencing and annotation, microarray analysis, disease resistance;
rice genome sequencing and annotation; tomato EST sequencing;
development of computational methods for plant genomics.  Please
contact Dr. C.M. Ronning, Collaborative Investigator, at
cronning at tigr.org.


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