Positions in functional genomics of RLKs in Arabidopsis

Ramesh Raina rxr21 at psu.edu
Mon Apr 29 16:48:55 EST 2002


Receptor-like kinases (RLKs) are involved in signal perception 
through the cell surface. In Arabidopsis RLKs constitute a large 
family consisting of more than 600 family members (Shiu and Bleecker, 
2001, PNAS, 98:10763-68). However, the function of very few of these 
genes is known. The goal of this project is to develop Arabidopsis 
plants expressing chimeric RLKs which induce visible responses 
(hypersensitive response-like necrotic lesions and express GFP 
reporter gene) when they sense various chemical and biological agents 
of interest. Several hundred genes have been targeted for this 
project. Transgenic plants expressing these chimeric RLKs will be 
screened to identify the receptor(s) involved in perception of many 
stimuli of interest. A combination of transient and transgenic 
approaches will be used to construct transgenic plants expressing 
chimeric RLKs. This is a collaborative project which merges molecular 
biology, biochemistry and chemical ecology, and involves the 
laboratories of Dr. Jack Schultz and Dr. Ramesh Raina at Penn State 
University; it is funded by DARPA.

1. POSTDOCTORAL RESEARCH ASSOCOATES (several positions): A Ph.D. in 
molecular biology is required. Successful candidates will have a 
strong background in Plant Molecular Biology, experience with DNA/RNA 
analysis, and construction and analysis of transgenic plants. 
Experience with transient assays (protoplast or cell suspension), 
plant-pathogen interactions, or receptor kinases is a plus but not 
necessary. Successful candidates should be able to work independently 
and as team players.

2. RESEARCH TECHNICIANS (several positions): A BS. or equivalent 
degree in Biology or related area is required. Applicants with more 
than 2 years of experience in molecular biology can be considered for 
the Senior Research Technician position. Successful candidates will 
assist the members of the group with molecular biology experiments 
such as DNA and RNA analysis, PCR, plant transformation, plant 
responses to stimuli, etc. Organizational skills and the ability to 
work collaboratively with various members of the groups is essential.

These positions are available starting July 1, 2002. Earlier start 
dates will also be considered. Applications for these positions 
should include a letter stating experience and interest along with a 
curriculum vitae and the names, addresses, e-mail addresses and 
telephone numbers of three references. Applications or further 
enquiries about the project or these positions should be directed to: 
Dr. Ramesh Raina, Department of Biology, 505 Wartik Laboratory, Penn 
State University, University Park, PA 16802, USA. Telephone: 
814-865-7127, FAX: 814-863-1357, email: rxr21 at psu.edu OR Dr. Jack 
Schultz, Department of Entomology, Penn State University, University 
Park, PA 16802, USA. Tel: 814-863-4438, FAX: 814-863-4439, email: 
ujq at psu.edu.

Penn State University is an equal opportunity employer.

Ramesh Raina
Department of Biology  
505 Wartik Laboratory                                              
The Pennsylvania State University
University Park, PA 16802  USA
Tel:  814-865-7127 (Office)
Tel:  814-865-0924 (Lab)
Fax: 814-863-1357

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