Post-Doc, Signaling and Cell Biology

Dan Szymanski dszyman at
Mon Apr 21 16:14:14 EST 2003

Post-Doc Position, Signaling
and the Cell Biology

Leaf and root epidermal development is being used as a model process
to better understand how and why the cytoskeleton is polarized during
cell and tissue morphogenesis. We have recently cloned several genes
that encode signaling proteins (a LRR-domain containing protein, a
putative ROP GTPase activator) and others that encode proteins that
appear to directly regulate cytoskeletal dynamics. In addition to cell
shape and cytoskeletal defects, many of the mutants display altered
organelle and vesicle dynamics. The next phase of the project is
focused on understanding gene function in the context of cell
morphogenesis. Possible lines of investigation include live cell
imaging and protein localization, biochemical analysis of the
composition and activity of the signaling complexes, as well as
genetic dissection of the signaling pathways. Applicants should have
experience in molecular biology and/or biochemistry.

For more information visit:

If interested please contact:

Dr. Dan Szymanski

Assistant Professor

dszyman at

Purdue University

1150 Lilly Hall of Life Sciences

West Lafayette, IN 47907765-494-8092


Purdue University is an equal
opportunity/affirmative action employer.

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