postdoctoral position

Nilgun Tumer tumer at AESOP.RUTGERS.EDU
Tue Aug 5 12:04:18 EST 2003

Postdoctoral Research Position
Rutgers University
New Brunswick, NJ

   A postdoctoral research associate position is available at the Biotech
Center at Cook College/Rutgers University to study the regulation of
expression of ribosomal protein L3 in plants and its role in plant growth
and development.  Studies of ribosomal protein L3 in yeast have revealed
important functions for this protein in translation, ribosome biogenesis
and virus resistance. L3 participates in the formation of the
peptidyltransferase center. Mutations in L3 confer resistance to the
peptidyltransferase inhibitors, trichodermin and anisomycin, affect
assembly of the 60S ribosomal subunit and inhibit translation of the double
stranded RNA of the M1 killer virus by increasing the programmed -1
frameshifting efficiency.  L3 acts as a receptor for pokeweed antiviral
protein (PAP), a plant ribosome inactivating protein that binds the
ribosome and depurinates the large rRNA.  Our recent results indicate that
L3 plays an important role in rRNA processing, cell division and plant
growth.  A postdoctoral research associate is sought to characterize the
mechanism by which the two different L3 genes regulate their expression and
affect translation, ribosome biogenesis and cell cycle in
plants.  Qualifications include a Ph.D. in a related field, experience with
RNA biochemistry and molecular biology and demonstration of an active
publication record.  Please send the names and addresses of three
references to Dr. Nilgun Tumer, Biotech Center, Foran Hall, 59 Dudley Road,
Cook College, Rutgers University, New Brunswick, NJ 08901-8520.

email:  <mailto:tumer at>tumer at

Dr. Nilgun E. Tumer                                     Tel:  732-932-8165X215
Professor                                               Fax: 732-932-6535

Biotechnology Center
Rutgers, The State University of New Jersey
Cook College
Foran Hall
59 Dudley Road
New Brunswick, NJ 08901-8520



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