Postdoc Position in plant pathogen interactions

Sarah Grant sgrant at
Thu Jul 29 13:27:39 EST 2004

Postdoctoral Position Available

Laboratory of Sarah Grant and Jeff Dangl
Department of Biology
University of North Carolina at Chapel Hill
Chapel Hill, NC 27599
Tel: (919) 962-7253
Email: <mailto:sgrant at>sgrant at

Little is known about molecular host-pathogen interactions in natural 
settings. We are initiating a new NSF funded study on the evolution 
and diversity of virulence factors in the agronomically important 
bacterial pathogen of potatoes, Erwinia carotovora pv. carotovora 
(Ecc). The goal of this project is identification of translocated 
virulence factors from Ecc collected from a variety of diverse hosts 
and environments in order to understand the extent of pathogen 
diversity and characterize the mechanisms of virulence used by this 
pathogen. This project is a collaboration with three laboratories at 
the University of Wisconsin with expertise in Ecc-host interactions 
(Charkowski and Yang) and evolution of bacterial pathogenicity 
(Perna). We have developed a high-throughput screening method to 
identify virulence factors that are translocated into host cells from 
bacterial pathogens. We are looking for someone to direct this high 
throughput screening effort, develop methods to manage and utilize 
the data generated and initiate novel studies of the virulence 
mechanisms of Ecc.
     The successful applicant will need to demonstrate, via 
publications in peer-reviewed journals: 1) expertise in microbial 
genetics/genomics, 2) all standard molecular cloning skills including 
construction of genomic libraries, 3) some knowledge of database 
management, 4) the ability to communicate effectively in both written 
and spoken English and 5) the desire and ability to interact with 
researchers in distant laboratories and to work in a research team 
environment. Please send a CV and publication list and the names and 
email addresses of three references to Sarah Grant at 
<mailto:sgrant at>sgrant at
     Preferred start date will be between October 2004 and January 2005.

Sarah R. Grant
Research Assistant Professor
Department of Biology
University of North Carolina at Chapel Hill
Chapel Hill NC, 27599-3280
Tel: (919) 962-7253
Fax: (919) 962-1625
Email: <mailto:sgrant at>sgrant at
Url: <>

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