[Arabidopsis] Postdoctoral Position - immediate opening

Copenhaver, Gregory P (Biology) via arab-gen%40net.bio.net (by GCopenhaver from bio.unc.edu)
Tue Mar 24 09:06:00 EST 2009


Postdoctoral Position: Regulation of Meiotic Recombination

University of North Carolina at Chapel Hill

   

A postdoctoral position is open immediately in the lab of Dr. Gregory
Copenhaver (http://www.bio.unc.edu/faculty/copenhaver/lab/) in the
Department of Biology (http://www.bio.unc.edu/) at The University of
North Carolina (http://www.unc.edu/) in beautiful Chapel Hill.  The
position is fully funded for a three year period including health
benefits.  The long-term goal of the project is to understand how
meiotic recombination is regulated in plants.  Specific goals include
characterizing novel recombination mutants recently discovered in the
lab and using reverse genetics to evaluate the influence of specific
target genes on crossover control.  Meiotic recombination results in the
heritable rearrangement of DNA, primarily through reciprocal exchange
between homologous chromosome or gene conversion.  In plants these
events are critical for ensuring proper chromosome segregation,
facilitating DNA repair and providing a basis for genetic diversity.  We
have developed as a facile system for visually assaying recombination
using tetrad analysis in Arabidopsis.  This work builds on the previous
accomplishments of our lab previous accomplishments including: 

 

1. Berchowitz LE, Copenhaver GP (2008) Fluorescent Arabidopsis tetrads:
A visual assay for quickly developing large crossover and crossover
interference datasets.  Nature Protocols 3(1): 41-50.

2.         Berchowitz LE, Francis KE, Bey AL, Copenhaver GP (2007) The
Role of AtMUS81 in Interference-Insensitive Crossovers in A. thaliana.
PLoS Genetics 3(8): e132 doi:10.1371/journal.pgen.0030132.

3.         Francis KE, Lam SY, Harrison BD, Bey AL, Berchowitz LE,
Copenhaver GP (2007) Pollen-tetrad based visual assay for meiotic
recombination in Arabidopsis.  Proc. Natl. Acad. Sci. USA 104:
3913-3918.

The successful applicant will have a strong background in molecular
biology (plant-specific background a plus but not required) and will
have the opportunity to gain experience in forward and reverse genetics,
microscopy and statistical analysis.  Preference will be given to
candidates who are able to begin the position soon.  Applicants should
submit a CV, a short description of research experience and three
references (including phone and email addresses) by email to Dr. Gregory
Copenhaver (gcopenhaver from bio.unc.edu).

 

 

Dr. Gregory P. Copenhaver, Ph.D.

Associate Professor

Department of Biology

Carolina Center for Genome Sciences

UNC at Chapel Hill

CB#3280, Coker Hall 305

Chapel Hill, NC 27599

Phone: 919-843-4026

Fax: 919-962-1625

 



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