[Arabidopsis] 2 Post-Doc Positions, RNA Biology and Bioinformatics
(by G.G.Simpson from dundee.ac.uk)
Wed Sep 2 03:52:03 EST 2009
2 x Postdoctoral Research Assistants
College of Life Sciences, Dundee University
Alternative Polyadenylation: RNA Biology and Bioinformatics
Grade 7 (Starting Salary £28,839 – £31,513 pa)
An exciting opportunity to join a £1million BBSRC funded project that
will combine cutting-edge technology for DNA sequencing and
computational analysis with molecular genetics to answer fundamental
questions in gene regulation.
We have discovered genetically independent regulators of alternative
polyadenylation while studying Arabidopsis flower development. Although
this mode of gene regulation is common in eukaryotes, it is surprisingly
poorly understood. This project will dissect the mechanisms and roles of
alternative polyadenylation. Our programme addresses the molecular
mechanisms involved and uses next generation sequencing to reveal and
quantify genome-wide shifts in poly(A) site selection.
The project fuses the extensive experience of Dr Gordon Simpson in
Arabidopsis RNA biology, who will lead the molecular aspects of the
work, with the computational skills of Prof Geoff Barton, who will lead
the bioinformatics analysis. The Barton group has long-standing
expertise in developing computational techniques that are widely applied
and has had recent successful experience in studying RNA processing and
expression by analysis of next generation sequencing data.
integrated nature of this programme offers the opportunity for the
molecular and bioinformatics analyses to be iteratively validated and
The first post (LS/2917) requires a Molecular Biologist and previous
experience with the molecular analysis of either RNA processing or
genetic analysis of Arabidopsis would be an advantage.
The second post (LS/2918) requires an individual with strong data
analysis and software development expertise. These skills may have been
gained in bioinformatics, or in related scientific fields such as
Dundee is a centre of excellence in life sciences research and combines
quality of life with quality of science. Consistently topping polls in
The Scientist magazine of best places to work, staff of more than 50
different nationalities create a vibrant international working
environment, with a particularly active Post-Doc Association.
Gordon Simpson’s lab web site:
Geoff Barton’s lab web site: www.compbio.dundee.ac.uk/
Both positions are full-time for 3 years.
HOW TO APPLY:
Applications in the form of a CV and covering letter,
including the names and addresses of 3 referees and a list of
publications, should be sent to email address (
http://mini.dundee.ac.uk/locate/?2009733650hu250711 ) .
Alternatively, please send 2 hard copies of your CV and covering letter
to Human Resources, College of Life Sciences, MSI/WTB/JBC Complex,
University of Dundee, DD1 5EH. Applicants will only be contacted if
invited for interview.
The University of Dundee is committed to equal
opportunities and welcomes applications from all sections of the
The University of Dundee is a Scottish Registered Charity,
How to apply:
Apply by Curriculum Vitae (CV) and covering letter.
You must also return the Supplementary Information Forms (
) (PDF) 36KB with your application.
Please remember to quote the job reference.
Please return your application to: (use postal or email address from
the advert itself above)
The University of Dundee and the City of Dundee (
Division of Plant Sciences
College of Life Sciences
University of Dundee
g.g.simpson from dundee.ac.uk
Direct Dial: 44 1382 568572
The University of Dundee is a registered Scottish charity, No: SC015096
More information about the Arab-gen