Bio.com News and Updates

[Bio.com Newsletter]

Bio.com News & Updates
November 21, 2001
www.bio.com

The Life Sciences Portal

Jobs . News . Research . Reports . Software . Protocols . Tools
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CONTENTS:
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1.  Biotech News & Features: "A New Clue to How Viruses Infect Cells"
2.  InFocus Webcast: "Cell-Based Screening in Drug Discovery"
3.  Career Center: Set Up Your Free Profile Today
4.  Jobs of the Week: "Laboratory Project Coordinator" and others
5.  Featured Employer:  eXegenics
6.  Industry Reports and Software: "LABTrack"
7.  Laboratory Protocols: "In-Gel Kinase Assay"
8.  Product Highlight:  MegaBACE 4000 DNA Analysis System

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1.  BIOTECH NEWS & FEATURES
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-Developing Methods of Genetic Analysis to Improve Cancer Risk Assessment
http://www.bio.com/Redirectors/LinkRedirect11_20.jhtml?link=1
Using genotypic selection, the oncogene and tumor suppressor gene
Mutations that are the earliest persistent changes in tumor development
can be measured and used as biomarkers for cancer risk. Three different
genotypic selection methods have been developed.

-DNA Methylation Potential New Prostrate Cancer Diagnostic
http://www.bio.com/Redirectors/LinkRedirect11_20.jhtml?link=2
Scientists at Johns Hopkins have found that measuring the level of a DNA
methylation could greatly strengthen standard detection of curable,
early-stage prostate cancer. The report is published in the November 21,
2001 issue of the Journal of the National Cancer Institute.

-Space-Travel Stress Reactivates EBV Virus
http://www.bio.com/Redirectors/LinkRedirect11_20.jhtml?link=3
Every time astronauts blast off for outer space, they carry tiny stowaways
with them-viruses that have been latent in their bodies since childhood.
These viruses, typically including Epstein-Barr, herpes simplex and
varicella zoster (which causes chicken pox in children) exist in almost
everyone, but they have a special significance for astronauts, whose
immune systems are weakened by the unique stresses of spaceflight.

-Attractive, Defensive Roles for Flower Pigments
http://www.bio.com/Redirectors/LinkRedirect11_20.jhtml?link=4
When some insects zero in on a flower for nectar, their ultraviolet vision
is guided by a bull's-eye "painted" on the plant by chemical compounds.
Now, chemical ecologists at Cornell University have discovered a second
job for these compounds: warding off herbivores.

-A New Clue to How Viruses Infect Cells
http://www.bio.com/Redirectors/LinkRedirect11_20.jhtml?link=5
In a development that holds ramifications for gene therapy and
infection-fighting drugs, a research collaboration led by Carlos
Bustamante of Berkeley Lab's Physical Biosciences Division has
discovered the mechanism by which at least some viruses infect the
cells of other organisms with their DNA. The mechanism involves one
of the most powerful biomolecular motors ever observed.


For more Industry News, go to:
http://www.bio.com/industryanalysis/industryanalysis_news.jhtml

For more Research News, go to:
http://www.bio.com/newsfeatures/newsfeatures_research.jhtml


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2.  INFOCUS WEBCAST:
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*Click here for a Free T-shirt and a chance to win COBRA 2-way radios
(set of 2) with charger from Amersham Biosciences:
http://www.bio.com/Redirectors/LinkRedirect11_20.jhtml?link=10

*To listen to the audio file from our last panel discussion, "Cell-Based
Screening in Drug Discovery & Development," go to:
http://chat.bio.com:8000/audio/cellscreen_11152001.mp3
(use any mp3 player to listen to archived audio files)

*To read the transcript of the discussion, go to:
http://www.bio.com/newsfeatures/newsfeatures_infocus.jhtml?action=transcript
(Be sure to copy the entire URL and paste it into your browswer)

*Both the transcript and audio file from our panel discussion on
"Chemical Genomics" are now available.

-To read the transcript, go to:
http://www.bio.com/file_temp/chemgenomics.pdf

-To listen to the audio file, go to:
http://chat.bio.com:8000/audio/ChemGene_10042001.mp3

*Our next InFocus feature, "DNA Microarrays: Platforms and Applications,"
begins with a panel discussion on Thursday, December 6 at 1:00pm
Pacific Time.
http://www.bio.com/Redirectors/LinkRedirect11_20.jhtml?link=6

*Archive of past InFocus events:
http://www.bio.com/newsfeatures/newsfeatures_fochives.jhtml


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3.  CAREER CENTER
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Bio.com offers the most comprehensive online Career Center in the life
sciences industry.

Set up your free personal profile today at:
http://career.bio.com/pages/myresume.cfm?object=1&action=New

Browse all job postings:
http://career.bio.com/pages/featured.cfm?1


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4.  JOBS OF THE WEEK
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Look at what's new on Bio.com Career Center this week:

-eXegenics:  Scientist-Informatics and Screening
http://career.bio.com/pages/jobsearch.cfm?object=5&job=774867&action=View

-Genomics-Based Biopharmaceutical Company:  Director of Pharmacogenomics
http://career.bio.com/pages/jobsearch.cfm?object=5&job=775236&action=View

-West Pharmaceuticals Company:  Laboratory Project Coordinator
http://career.bio.com/pages/jobsearch.cfm?object=5&job=775060&action=View

-Sunesis Pharmaceuticals:  Research Associate-Medicinal and Synthetic
Organic Chemistry
http://career.bio.com/pages/jobsearch.cfm?object=5&job=775251&action=View

-Biotechnology Company, California:  Director of Fermentation and Process
Development
http://career.bio.com/pages/jobsearch.cfm?object=5&job=775369&action=View

-Biotechnology Company, California:  Senior Scientist, Toxicologist
http://career.bio.com/pages/jobsearch.cfm?object=5&job=775237&action=View


Browse all jobs at http://career.bio.com/pages/featured.cfm


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5.  FEATURED EMPLOYER
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eXegenics Inc. is a biotechnology company that has developed a suite of
platform technologies - QCT (Quantum Core Technology) and OASIS (Optimized
Anti-Sense Inhibitory Sequence) to accelerate and enhance the discovery and
creation of novel pharmaceutical products.  The company is also
engaged in a collaborative program with Bristol Myers Squibb to optimize
the production of paclitaxel, the active ingredient in Taxol.
http://career.bio.com/pages/job_get.cfm?EmployerID=1619


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6.  INDUSTRY REPORTS & SOFTWARE
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1.  Target Identification and Validation
http://www.bio.com/Redirectors/LinkRedirect11_20.jhtml?link=7

2.  Drug Discovery Industry Review
http://www.bio.com/Redirectors/LinkRedirect11_20.jhtml?link=8

3.  LABTrack
http://www.bio.com/Redirectors/LinkRedirect11_20.jhtml?link=9


For more reports available on Bio.com, visit:
http://bio.com/store/store_publications.jhtml


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7.  LABORATORY PROTOCOLS
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Register here http://www.bioprotocol.com/register.jsp
for access to the highest quality collection of laboratory
protocols on the web, FREE!

*Preview some of our latest additions:

-Infection of Cells with Retroviruses
http://www.bioprotocol.com/transfer.jsp?pgId=11000

-Apoptosis Assay using DNA Laddering
http://www.bioprotocol.com/transfer.jsp?pgId=11001

-In-Gel Kinase Assay
http://www.bioprotocol.com/transfer.jsp?pgId=11002


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8.  PRODUCT HIGHLIGHT
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MegaBACE 4000 DNA Analysis System from Amersham Biosciences

384 capillaries:
   Four times the throughput
   Lowest sequencing cost per base
   More genomes per week
   Better efficiencies: less labor and less space

For more info on MegaBACE visit
http://www.amershambiosciences.com/application/MegaBACE/


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