News & Updates Newsletter newsletter at
Wed Oct 10 20:33:12 EST 2001 News & Updates
October 10, 2001

The Life Sciences Portal

Jobs . News . Research . Reports . Software . Protocols . Tools

1.  Science News: "Mass Spectrometry: The Basics" and others
2.  InFocus Webcast: Audio file for "Chemical Genomics "
3.  Career Center: Find the Latest Job Search Tools on's Career Center!
4.  Jobs of the Week: "Computer Validation Engineers" and others
5.  Industry Reports: "The Business Case for Pharmacogenomics" and others
6.  Laboratory Protocols: "Dot Blotting of DNA"


This newsletter is sponsored by:  BioWorld Today

The BioWorld Executive Compensation Report 2002, a top-selling
report containing complete rankings of CEO, CFO and R&D executive
compensation at 256 biotechnology companies, is now available!
This report is the only objective study of current salaries,
stock options, and bonuses of top biotechnology executives!


Ion Channel Protein, CatSper, Controls Sperm Motility
An ion channel protein that plays a central role in sperm motility could
be an enticing target for a new type of contraceptive that could be taken
by either men or women to block fertilization. The newly discovered
protein, called CatSper, controls the flow of calcium into the tails of

Featured Molecules: Poliovirus and Rhinovirus
Viruses are biological hijackers. They attack a living cell and force it
to make many new viruses, often destroying the cell in the process.
Picornaviruses or "little RNA viruses,"  such as rhinovirus and poliovirus
are among the most simple viruses.  They are composed of a modular protein
shell, which seeks out and binds to a target cell surface, surrounding a
short piece of RNA, which contains all of the information needed to co-opt
the cell's machinery and direct the construction of new viruses.

Promising Results with Antisense Drug ISIS 2302
Data from a Phase II clinical trial demonstrated that the antisense drug
ISIS 2302 improved symptoms of patients with active distal ulcerative
colitis (UC). Patients receiving an enema formulation of ISIS 2302
experienced a dose-dependent reduction in disease activity index score
(DAI) and clinical activity index score (CAI).

Nanogen Receives U.S. Army Grant to Develop Biowarfare Detection Systems
Nanogen, Inc. (Nasdaq: NGEN) announced today that it has been awarded a
three-year, $1.5 million grant from the U.S. Army to continue development
of miniaturized electronic devices for isolating and detecting biological
warfare and infectious disease agents from human blood samples.

Mass Spectrometry: The Basics
Mass spectrometry has become a powerful tool for studying proteins, peptides
and proteomes. This article provides a brief overview of the basic concepts
involved, and lists the main instrument and software providers.

For more Industry News, go to:

For more Research News, go to:


*To listen to the audio file from our last panel discussion, "Drug
Discovery 2001: Chemical Genomics," go to:
(use any mp3 player to listen to archived audio files)

*To read the transcript of an interview with Randy King, from the
Institute of Chemistry and Cell Biology at Harvard, go to:

*Our next InFocus feature, "Therapeutic Targets: Apoptosis," begins with a
panel discussion on Thursday, October 18 at 10am Pacific Time.

=========================================================================== offers the most comprehensive online Career Center in the life
sciences industry.

Set up your free personal profile today at:

Browse all job postings:


Look at what's new on Career Center this week:

1.  Global Health Company, MA:  HTS Sales Specialist

2.  Biotechnology Company, Boston, MA:  Quality Assurance Director/Quality
Assurance Manager/Quality Manager

3.  Biotechnology Consulting Company, Philadelphia:  Computer Validation
(Be sure to copy the entire URL and paste it into your browser)

Browse all jobs at


**To view each report, please be sure to copy the entire URL and paste it
into your browser

1.  Bones and Joints: Drugs, Devices and Regenerative Technologies

2.  The Business Case for Pharmacogenomics (2nd Edition)

3.  Functional Proteomics: Short-Cuts to Drug Discovery

For more reports available on, visit:


Register here
for access to the highest quality collection of laboratory
protocols on the web, FREE!

*Preview some of our latest additions:

-Synthesis of Degenerate Oligonucleotide Inserts for Phage-Display

-Calibrating a pH Meter and Measuring the pH of a Solution

-Dot Blotting of DNA


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