News & Updates Newsletter newsletter at
Tue Oct 23 20:37:52 EST 2001 News & Updates
October 24, 2001

The Life Sciences Portal

Jobs . News . Research . Reports . Software . Protocols . Tools

1.  Science News: "Anthrax Toxin Receptor Identified"
2.  InFocus Webcast: Audio file for "Apoptosis"
3.  Career Center: Set Up Your Free Profile Today!
4.  Jobs of the Week: "Cell Biologist" and others
5.  Featured Employer:  R&D Systems
6.  Industry Reports: "Short-Cuts to Drug Discovery"
7.  Laboratory Protocols: "Double-Stranded cDNA Synthesis for Cloning"


This newsletter is sponsored by:  Accelrys

Accelrys is a leading provider of simulation and informatics tools that
accelerate the design, discovery and development of new chemicals and
pharmaceuticals.  Our solutions enhance scientific insight and promote the
flow of data, information, and knowledge throughout your discovery
program, supporting your decision making process and enabling you to make
the most intelligent use of your resources.


Microarrays Identify Genetic Changes in Biofilms
Using a technology known as microarray analysis, University of Iowa
researchers and their collaborators at Harvard University, Northwestern
University and the University of Washington, Seattle, have identified a
subset of genes in a bacterium that behave differently when the organism
exists as a biofilm. These findings may lead scientists to the genetic
causes of increased antibiotic resistance in biofilms. The study results
appear in the October 25, 2001 issue of the journal Nature.

Anthrax Toxin Receptor Identified
Researchers at UW Medical School's McArdle Laboratory for Cancer Research
and their collaborators at Harvard Medical School have found the receptor
that anthrax toxin binds to in order to enter cells. The finding, to
appear in the November 8, 2001 issue of Nature, represents a major
advance in understanding exactly how the toxin kills host cells,
leading quickly to death. The structure consists of a single protein
the researchers call anthrax toxin receptor (ATR).

Advanced Tissue Sciences Demonstrates Success of Tissue-Engineered Blood
Advanced Tissue Sciences, Inc. presented research at the annual Biomedical
Engineering Society Meeting at Duke University in North Carolina
supporting the potential of the company's tissue-engineering technology
to replace life-threatening damaged blood vessels in the heart, legs or
other areas of the body prone to vascular disease.

Expert: Anthrax Scare Overblown
The current anthrax scare would abate if the public understood the basic
science behind the disease and its transmission, according to Swarthmore
College microbiologist Amy Cheng Vollmer.

Featured Molecules: Poliovirus and Rhinovirus
Picornaviruses, or "little RNA viruses," are among the most simple
viruses.  They are composed of a modular protein shell, which seeks out
and binds to a target cell surface, surrounding a short piece of RNA,
which contains all of the information needed to co-opt the cell's
machinery and direct the construction of new viruses.

Geron Licenses Telomerase Technology to Dendreon
Geron Corporation announced today that the Company has licensed its
telomerase technology to Dendreon Corporation for use in cancer
immunotherapy. Dendreon has been granted a non-exclusive license to use
telomerase as an antigen in a vaccine intended to induce a specific immune
response against malignant tumors.

For more Industry News, go to:

For more Research News, go to:


* "Therapeutic Drug Targets: Apoptosis,":  To listen to the audio file
from our last panel discussion go to:
(use any mp3 player to listen to archived audio files)

*To read the transcript of our recent panel discussion on Chemical
go to:

*Our next InFocus feature, "Therapeutic Drug Targets: Angiogenesis,"
begins with a panel discussion on Thursday, November 1 at 10:00am Pacific Time.

=========================================================================== offers the most comprehensive online Career Center in the life
sciences industry.

Set up your free personal profile today at:

Browse all job postings:


Look at what's new on Career Center this week:

1.  R&D Systems Inc.:  Scientist

2.  Medical Device Company, Boston:  Quality Assurance Engineer/Quality

3.  Harmonia Medical Technologies:  Cell Biologist

4.  Biotechnology Company, Ohio:  Principal Scientist/Group Leader

5.  Pharmaceutical Company, Ohio:  Quality Control Manager

6.  Pharmaceutical Company, New York:  Cardiovascular Product Manager

7.  Start- up Biotechnology Company, Pennsylvania:  Director of Antibody

Browse all jobs at


R&D Systems, Inc., which is located in Minneapolis, Minnesota,
develops and manufactures biotechnology products
including purified proteins (cytokines) and antibodies that
are sold exclusively to the research market, and assay kits
which are sold to the research and clinical diagnostic markets.

Browse and apply for a job at R&D Systems today:


1.  Bones and Joints: Drugs, Devices and Regenerative Technologies

2.  The Business Case for Pharmacogenomics (2nd Edition)

3.  Functional Proteomics: Short-Cuts to Drug Discovery

For more reports available on, visit:


Register here
for access to the highest quality collection of laboratory
protocols on the web, FREE!

*Preview some of our latest additions:

-Double-Stranded cDNA Synthesis for Cloning

-Nested Deletions Using Exonuclease III and Mung Bean Nuclease

-Antiphosphotyrosine Western Blot Analysis


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